| Introductory Comments / Robert W. Ledeen |
| Sphingosine and Its Derivatives as Signaling Molecules / Part 1： |
| Signal Transduction Through Glyco(sphingo)lipids: Introduction and Recent Studies on Glyco(sphingo)lipid-enriched Microdomains / Sen-itiroh Hakomori ; Soichiro Yamamura ; Kazuko Handa |
| Sphingosine-1-Phosphate in Cell Growth and Cell Death / Sarah Spiegel ; Olivier Cuvillier ; Lisa C. Edsall ; Takafumi Kohama ; Ramil Menzeleev ; Zoltan Olah ; Ana Olivera ; Grisha Pirianov ; Dianne M. Thomas ; Zhenxing Tu ; James R. Van Brocklyn ; Fang Wang |
| Sphingosine-1-Phosphate as an Intercellular Signaling Molecule / Yasuyuki Igarashi |
| Coupling of the p75 Neurotrophin Receptor to Sphingolipid Signaling / Rick T. Dobrowsky ; Bruce D. Carter |
| Metabolic Fate of Exogenous Sphingosine in Neuroblastoma Neuro2A Cells: Dose-dependence and Biological Effects / Laura Riboni ; Rosaria Bassi ; Antonella Caminiti ; Alessandro Prinetti ; Paola Viani ; Guido Tettamanti |
| Sphingolipids as Receptor Modulators / Part 2： |
| Sphingolipids as Receptor Modulators: An Overview / Allan J. Yates ; Arfaan Rampersaud |
| Differential Involvement of Gangliosides versus Phospholipids in the Process of Temperature Adaptation in Vertebrates: A Comparative Phenomenological and Physicochemical Study / H. Rahmann ; U. Jonas ; T. Kappel ; H. Hildebrandt |
| Myelin-associated Glycoprotein Binding to Gangliosides: Structural Specificity and Functional Implications / Ronald L. Schnaar ; Brian E. Collins ; Latasha P. Wright ; Makoto Kiso ; Michael B. Tropak ; John C. Roder ; Paul R. Crocker |
| GM1 Ganglioside-induced Modulation of Opioid Receptor-mediated Functions / Stanley M. Crain ; Ke-Fei Shen |
| The Role of GM1 Ganglioside in Regulating Excitatory Opioid Effects / G. Wu ; Z.-H. Lu ; T. J. Wei ; R. D. Howells ; K. Christoffers ; R. W. Ledeen |
| Sphingolipid Metabolism and Transport / Part 3： |
| Sphingolipid Metabolism: Sphingoid Analogs, Sphingolipid Activator Proteins, and the Pathology of the Cell / K. Sandhoff ; T. Kolter ; G. van Echten-Deckert |
| Use of BODIPY-labeled Sphingolipids to Study Membrane Traffic along the Endocytic Pathway / Richard E. Pagano ; Chii-Shiarng Chen |
| Gangliosides and Neuronal Differentiation / Part 4： |
| The Role of GM1 and Other Gangliosides in Neuronal Differentiation: Overview and New Findings / Gusheng Wu ; Zi-Hua Lu ; Diane Kozireski-Chuback ; Yu Fang |
| Regulatory Roles for Sphingolipids in the Growth of Polarized Neurons / Anthony H. Futerman ; Swetlana Boldin ; Adi B. Brann ; Andreas Schwarz ; Rivka Zisling |
| GM2 Ganglioside as a Regulator of Pyramidal Neuron Dendritogenesis / Steven U. Walkley ; Donald A. Siegel ; Kostantin Dobrenis ; Mark Zervas |
| Significance of Gangliosides in Neuronal Differentiation of Neuroblastoma Cells and Neurite Growth in Tissue Culture / Harald Rosner |
| Glycosphingolipid Biosynthesis May Not Be Necessary for Vertebrate Brain Development / John V. Brigante ; Thomas N. Seyfried |
| A Synthetic Ceramide Analog (L-PDMP) Up-regulates Neuronal Function / Jin-ichi Inokuchi ; Akihiro Mizutani ; Masayuki Jimbo ; Seigou Usuki ; Kiwamu Yamagishi ; Hideo Mochizuki ; Kazuyo Muramoto ; Kazuo Kobayashi ; Yoichiro Kuroda ; Katsunori Iwasaki ; Yusuke Ohgami ; Michihiro Fujiwara |
| Gangliosides as Neuroprotective Modulators / Part 5： |
| GM1 and the Aged Brain / Maria Hadjiconstantinou ; Norton H. Neff |
| Gangliosides and Related Sialylcholesterol as Modulators of Synaptic Functions / Susumu Ando ; Yasukazu Tanaka ; Hatsue Waki ; Kazuo Kon ; Michiko Iwamoto ; Fumiko Fukui |
| Gangliosides and Neurotrophic Growth Factors in the Retina: Molecular Interactions and Applications as Neuroprotective Agents / Henri Dreyfus ; Jose Sahel ; Valerie Heidinger ; Saddek Mohand-Said ; Bernard Guerold ; Emmanuelle Meuillet ; Valerie Fontaine ; David Hicks |
| The Semisynthetic Glycosphingolipid LIGA[subscript 20] Potently Protects Neurons Against Apoptosis / Mariko Saito ; Alessandro Guidotti ; Martin J. Berg ; Neville Marks |
| Promotion of Neuronal Survival by GM1 Ganglioside: Phenomenology and Mechanism of Action / Giovanna Ferrari ; Lloyd A. Greene |
| Effects of GM1 Ganglioside Treatment on Dopamine Innervation in the Striatum in MPTP-treated Mice / David S. Rothblat ; J. S. Schneider |
| Exogenous Gangliosides: How Do They Cross the Blood-Brain Barrier and How Do They Inhibit Cell Proliferation? / Cara-Lynne Schengrund ; Christine M. Mummert |
| Sphingolipids in Neuropathology / Part 6： |
| The Role of Glycosphingolipids in Neurological Disorders: Mechanisms of Immune Action / Robert K. Yu ; Toshio Ariga |
| Molecular Mimicry in the Guillain-Barre Syndrome / K. A. Sheikh ; T. W. Ho ; I. Nachamkin ; C. Y. Li ; D. R. Cornblath ; A. K. Asbury ; J. W. Griffin ; G. M. McKhann |
| Antiglycolipid Antibodies in Motor Neuropathies / Nicole Baumann ; Marie-Luce Harpin ; Yannick Marie ; Karine Lemerle ; Benedicte Chassande ; Pierre Bouche ; Vincent Meininger ; Jean-Marc Leger |
| Guillain-Barre Syndrome and Fisher's Syndrome Following Campylobacter jejuni Infection / Nobuhiro Yuki ; Tadashi Miyatake |
| The Role of Antiglycolipid Antibodies in Neurological Disorders / Pam Fredman |
| Antiglycosphingolipid Immune Responses in Neurology: The Vienna Experience with Isotypes, Subclasses, and Disease / B. Gatterbauer ; A. Neisser ; H. Bernheimer ; B. Schwerer |
| Gangliosides as Potential Therapeutic Agents / Part 7： |
| GM1 Ganglioside in the Treatment of Parkinson's Disease |
| Clinical Trials of Pharmacotherapy for Spinal Cord Injury / Fred H. Geisler |
| The Role of the Monosialoganglioside, GM[subscript 1], as a Neuroprotectant in an Experimental Model of Cardiopulmonary Bypass and Hypothermic Circulatory Arrest / William A. Baumgartner ; J. Mark Redmond ; Kenton J. Zehr ; Malcolm V. Brock ; Elaine E. Tseng ; Mary E. Blue ; Juan C. Troncoso ; Michael V. Johnston |
| GM[subscript 1] Ganglioside for Acute Ischemic Stroke: Trial Design Issues / Milton Alter |
| Poster Papers |
| GM1 Administration Prevents Alterations in BCL-2 and Bax Expression in Substantia Negra Neurons Following MPTP Administration / D. W. Anderson ; J. C. Reed ; S. Krajewski |
| GM1 Ganglioside Inhibits Amyloid [beta] Protein Induced-Cytokine Release |
| Effects of Monosialoganglioside GM1 on Scopolamine-induced Amnesia / R. G. Bellot ; R. H. Silva ; R. Frussa-Filho |
| Inhibition of Neurite Growth by Ceramide in Rat Sympathetic Neurons / Elena P. de Chaves ; Miguel Bussiere ; Robert Campenot ; Dennis Vance ; Jean Vance |
| Induction of Trk Phosphorylation in Rat Brain by GM1 Ganglioside / A. M. Duchemin ; N. H. Neff ; M. Hadjiconstantinou |
| Effect of GM1 on TrkA Dimerization / Tahira Farooqui |
| GM1, Like IGF-I and GDNF, Prevents Neuronal Apoptosis / G. Ferrari ; M. C. Minozzi ; A. M. Zanellato ; B. Silvestrini |
| Photoreceptor Ganglioside Composition Changes During Postnatal Maturation of Retina |
| Cloning of Promoter for Rat GD3-Synthase Gene / L. Gao ; G. Zeng ; R. K. Yu |
| Glycolipids in Acoustic Neurinoma / Shizuo Handa ; Atsuko Ikeda ; Atsushi Komatsuzaki ; Takao Taki |
| GM1 Does Not Affect PDGF-BB-Stimulated [[superscript 3]H] Thymidine Incorporation or Neuritogenesis in SH-SY5Y Cells Treated with Phosphorothioate Oligonucleotides Antisense to PDGF-A / DiAnna L. Hynds ; Douglas Kniss |
| Coordinate Regulation of Stress-activated Protein Kinase and Mitogenactivated Protein Kinase Cascades in the Apoptotic Actions of Ceramide and Sphingosine / W. David Jarvis ; Frank A. Fornari, Jr. ; Michael J. Birrer ; Alex J. Freemerman ; Kelly L. Auer ; Paul Dent ; Steven Grant |
| Neuritogenic and Neuroprotective Activities of GM3 Ganglioside Derivatives / G. Kirschner ; E. Marchetto |
| Ganglioside GM1 Potentiates the Stimulatory Effect of Nerve Growth Factor on Peripheral Nerve Regeneration In Vivo / Raquel D. Lainetti ; Francisco C. Pereira ; Ciro F. Da-Silva |
| Expression of Recombinant [beta]-Platelet-derived Growth-factor Receptor in Sf9 Insect Cells as a Model to Study Receptor-Ganglioside Interactions / Scott W. McGee ; Hany E. Saqr ; Arfaan A. Rampersaud |
| Role of 9-O-Acetyl Gangliosides on Neurite Extension / Rosalia Mendez-Otero ; Helena Araujo ; Jonathan E. Friedman ; Meiga Menezes ; Erika M. A. Negreiros ; Marcelo F. Santiago |
| Long-term Effects of a Ganglioside Mixture on Chronic Chagasic Cardioneuropathy: Preliminary Results / J. Mitelman ; L. Gimenez ; N. J. Aparicio |
| Gangliosides: A Potential Therapeutic Approach in Retinal Ischemia / S. Mohand-Said ; M. Weber ; D. Hicks ; H. Dreyfus ; J. Sahel |
| Anti-GM2 Antibodies in Guillain-Barre Syndrome with Acute Cytomegalovirus Infection / Kazuo Nakamura ; Sachiko Irie ; Naomi Kanazawa ; Toyokazu Saito ; Yoichi Tamai |
| GM1 Activates the Map Kinase Cascade Through a Novel Wortmannin-Sensitive Step Upstream from c-RAF / A. A. Rampersaud ; J. R. Van Brocklyn ; A. J. Yates |
| Effects of Neonatal GM1 Administration on the Discriminative Avoidance Behavior of Adult Rats / M. Bergamo ; B. M. B. F. Vital |
| Ultramicroanalysis of Individual Molecular Species of Different Glycosphingolipids in Various Brain Tissues / T. Taketomi ; A. Hara ; K. Uemura ; E. Sugiyama |
| N,N-Dimethylsphingosine Induces Apoptosis by Inhibiting Sphingosine Kinase but Not Protein Kinase C. / L. C. Edsall ; G. Pirianov ; Z. Olah ; B. Kleuser ; O. Cuvillier ; A. Olivera ; T. Kohama ; R. Menzeleev ; S. Spiegel |
| Monosialoganglioside Increased the In Vivo Affinity of D[subscript 2] Receptors for Apomorphine in Supersensitive Rats / M. A. B. F. Vital ; J. Palermo-Neto |
| Developmental Expression of Rat Brain GD3- and GT3-Synthases / B. Freischutz ; A. Tokuda |
| Permanent Alteration of Endogenous Gangliosides in Neuroblastoma Cells by Stable Transfection with Antisense Vector / D. D. Li |
| Index of Contributors |
| Introductory Comments / Robert W. Ledeen |
| Sphingosine and Its Derivatives as Signaling Molecules / Part 1： |
| Signal Transduction Through Glyco(sphingo)lipids: Introduction and Recent Studies on Glyco(sphingo)lipid-enriched Microdomains / Sen-itiroh Hakomori ; Soichiro Yamamura ; Kazuko Handa |
| Sphingosine-1-Phosphate in Cell Growth and Cell Death / Sarah Spiegel ; Olivier Cuvillier ; Lisa C. Edsall ; Takafumi Kohama ; Ramil Menzeleev ; Zoltan Olah ; Ana Olivera ; Grisha Pirianov ; Dianne M. Thomas ; Zhenxing Tu ; James R. Van Brocklyn ; Fang Wang |
| Sphingosine-1-Phosphate as an Intercellular Signaling Molecule / Yasuyuki Igarashi |
| Coupling of the p75 Neurotrophin Receptor to Sphingolipid Signaling / Rick T. Dobrowsky ; Bruce D. Carter |
