Preface |
Sweetness and Sweeteners: What Is All the Excitement About? / Grant E. DuBois1: |
Structural Studies of the Sweetener Receptor |
Genetic Architecture of Sweet Taste / Alexander A. Bachmanov2: |
Making Sense of the Sweet Taste Receptor / Peihua Jiang ; Emeline Maillet ; Meng Cui ; Roman Osman ; Marianna Max ; Robert F. Margolskee3: |
T1R2, T1R3, and the Detection of Sweet Stimuli / Stephan Vigues ; Jeanette R. Hobbs ; Yiling Nie ; Graeme L. Conn ; Steven D. Munger4: |
In Vitro Models to Study Taste: Can Sweetness Be Modeled in a Dish? / Nancy E. Rawson ; M. Hakan Ozdener5: |
Modeling of the Sweetener Receptor |
Structure-Activity Relationship and AH-B after 40 Years / Terry E. Acree ; Michael Lindley6: |
Crystal Structures of the Sweet Protein MNEI: Insights into Sweet Protein-Receptor Interactions / 7: |
Molecular Models of Sweet Taste Receptors Provide Insights into Function / 8: |
Pharmacophore Modeling of Sweet and Bitter Tasting Molecules / Nicolas Froloff9: |
Multiple Receptors or Multiple Sites? Modeling the Human T1R2-T1R3 Sweet Taste Receptor / Gabriella Morini ; Angela Bassoli ; Piero A. Temussi10: |
Computational Docking to Sweet Taste Receptor Models / D. Eric Walters11: |
Sweet Taste Transduction |
What Can Psychophysical Studies with Sweetness Inhibitors Teach Us about Taste? / Veronica Galindo-Cuspinera ; Paul A. S. Breslin12: |
A Method to Measure Taste Qualities, Taste Intensity, and Temporal Profile of Compounds Aimed at Human Consumption by Taste Nerve Recordings in Monkeys / Göran Hellekant ; Yiwen Wang13: |
The Bittersweet Search for Bitter-Sweet Interactions: Cell to Cell Communication in the Taste Bud / M. Scott Herness ; Fang-li Zhao ; Yu Cao14: |
cAMP: A Role in Sweet Taste Adaptation / Nirupa Chaudhari ; Sue C. Kinnamon15: |
Saccharin: Artificial Sweetener, Bitter Tastant, and Sweet Taste Inhibitor / Marcel Winnig ; Christina Kuhn ; Oliver Frank ; Bernd Bufe ; Maik Behrens ; Thomas Hofmann ; Wolfgang Meyerhof16: |
Permeation of Amphipathic Sweeteners into Taste-Bud Cells and Their Interactions with Post-Receptor Signaling Components: Possible Implications for Sweet-Taste Quality / M. Naim ; M. E. Shaul ; A. I. Spielman ; L. Huang ; I. Peri17: |
Quantifying the Responses of Sweet-Sensitive Taste Bud Cells |
We Are What We Eat, but Why? Relationships between Oral Sensation, Genetics, Pathology, and Diet / Derek J. Snyder ; Valerie B. Duffy ; Susan E. Marino ; Linda M. Bartoshuk18: |
Perception and Acceptance of Sweeteners / Jeannine F. Delwiche ; Amanda R. Warnock19: |
Interindividual Differences of Taste Sensitivity in Humans and Hamsters: Multiple Receptor Sites for Single Organic Molecules / Annick Faurion20: |
The "Bitter-Sweet" Truth of Artificial Sweeteners / C. T. Simons ; C. Adam ; G. LeCourt ; C. Crawford ; C. Ward ; W. Meyerhof ; J. P. Slack21: |
The Use of Rodent Models to Link Neurobiological Processes with the Psychophysics of Sweet Taste / A.C. Spector ; S. Eylam ; C. D. Dotson22: |
Modulation of Sweet-Sensitive Taste Bud Cell Signaling |
Functional Characterization of the Human Sweet Taste Receptor: High-Throughput Screening Assay Development and Structural Function Relation / Xiaodong Li ; Guy Servant23: |
Development of Transient Receptor Potential Melanostatin 5 Modulators for Sweetness Enhancement / R. W. Bryant ; K. S. Atwal ; I. Bakaj ; M. T. Buber ; S. Carlucci ; R. Cerne ; R. Cortés ; H. R. Devantier ; C. J. Hendrix ; S. P. Lee ; R. K. Palmer ; C. Wilson ; Q. Yang ; F. R. Salemme24: |
Enhancers for Sweet Taste from the World of Non-Volatiles: Polyphenols as Taste Modifiers / Jakob P. Ley ; Maria Blings ; Susanne Paetz ; Günter Kindel ; Kathrin Freiherr ; Gerhard E. Krammer ; Heinz-Jürgen Bertram25: |
Evaluation of High-Intensity Sweetener Modulators / Cheryl R. Mitchell ; Richard Ray ; Marian Schwartz26: |
Improving the Taste of Artificial Sweeteners Using Flavors / Masashi Ishikawa ; Akio Nakamura ; Ayano Fujiki ; Junichi Ide ; Kensaku Mori27: |
Advances in the Discovery and Commercial Development of Synthetic Non-Caloric Sweeteners |
Why Should an Organic Chemist Study Sweet Taste? / Gigliola Borgonovo ; Gilberto Busnelli28: |
Sweeteners and Sweetness Modulators: Requirements for Commercial Viability / 29: |
Development of New, Low Calorie Sweetener: New Aspartame Derivative / Yusuke Amino ; Kenich Mori ; Yasuyuki Tomiyama ; Hiroyuki Sakata ; Takeshi Fujieda30: |
Challenges to Reducing Sugar in Foods / D. Kilcast ; C. den Ridder ; C. Narain31: |
Development of a New, No Calorie Commercial Sweetener Neotame / Indra Prakash ; Ihab E. Bishay32: |
Sensory Properties of Neotame: Comparison with Other Sweeteners / Susan S. Schiffman ; Elizabeth A. Sattely-Miller33: |
Recent Developments in Structure-Taste Studies of Sulfamates / William J. Spillane ; Damien P. Kelly ; Jean-Baptiste Malaubier ; Gary G. Hanniffy ; Brendan G. Feeney ; Catherine C. Coyle ; Lorraine M. Kelly ; Emer F. Thompson ; Danny G. Concagh ; Maryanne B. Sheahan34: |
Advances in the Discovery and Commercial Development of Natural Non-Caloric Sweeteners |
Neoculin as a New Sweet Protein with Taste-Modifying Activity: Purification, Characterization, and X-ray Crystallography / A. Shimizu-Ibuka ; Y. Morita ; K. Nakajima ; T. Asakura ; T. Terada ; T. Misaka ; K. Abe35: |
How Sweet It Is: Detailed Molecular and Functional Studies of Brazzein, a Sweet Protein and Its Analogs / Fariba Assadi-Porter ; Marco Tonelli ; James T. Radek ; Claudia C. Cornilescu ; John L. Markley36: |
Steviol Glucuronide as Excretion Product of Stevioside in Human volunteers: Lack of Carcinogenic Properties of Steviol Glycosides and Steviol / Jan M. C. Geuns37: |
Stevioside: A Safe Sweetener and Possible New Drug for the Treatment of the Metabolic Syndrome / 38: |
Indexes |
Author Index |
Subject Index |
Preface |
Sweetness and Sweeteners: What Is All the Excitement About? / Grant E. DuBois1: |
Structural Studies of the Sweetener Receptor |