Life, luck and logic in biochemical research / F. LynenChapter 1: |
Memories of Heidelberg - and of other places / T. Wieland2: |
Stepping stones - building bridges / B. Witkop3: |
Recollections: Vacillation of a classical biochemist / E.J.M. Helmreich4: |
These are the moments when we live! From thunberg tubes and manometry to phone, fax and fedex / H. Beinert5: |
Chorismic acid and beyond / F. Gibson6: |
Charge separation: A personal involvement in fundamental biological process / R.N. Robertson7: |
A biochemical autobiography / C. Rimington8: |
The importance of asking questions / P.N. Campbell9: |
Preface to Volume 40 |
Contributors to this Volume |
Wandering in the Fields of Science / S. Lifson |
Keilin and the Molteno / M.F. PerutzChapter 2: |
Introduction |
Keilin's favourite |
Warburton and the Siberian tick |
Frail health |
Lack of tenure |
An Australian Biochemist in Four Countries / E.C. SlaterChapter 3: |
Early life in Australia 1917-1939 |
Family background |
Schooling |
University education |
First research |
Australian Institute of Anatomy 1939-1946 |
World War II work interlude (1942-1943) |
Return to Canberra |
Cambridge 1946-1949 |
Molteno Institute |
Australian National University |
USA 1949-1950 |
Return to Cambridge 1950-1955 |
Enzyme kinetics |
Stability of isolated mitochondria |
Oxidative phosphorylation |
Offer of Amsterdam Chair |
Amsterdam 1955-1985 |
Starting in Amsterdam |
First five years in Amsterdam 1955-1960 |
Second five years 1961-1965 |
The second decade (1965-1975) |
Reorganization of Netherlands universities as a result of student pressure |
The last decade in Amsterdam 1975-1985 |
Extra-university activities |
Biochimica et Biophysica Acta |
Nomenclature |
EMBO and EMBL |
The Royal Netherlands Academy of Science |
The Netherlands Organization of Pure Scientific Research (ZWO) |
International Union of Biochemistry (IUB) |
China |
Retirement |
Concluding remarks |
References |
A Lifetime Journey with Photosynthesis / A.A. KrasnovskyChapter 4: |
Preface |
Childhood and primary education |
Professional education in chemistry |
War and the beginning of the biochemical career |
Photochemistry of chlorophyll |
Reversible chlorophyll photoreduction |
Reversible chlorophyll photooxidation |
Chase for free radicals |
Chlorophyll-photosensitized electron transfer |
The state of the photosynthetic pigments in living cells |
Reaction centers |
Inorganic models of reaction centers |
Involvement in problems of the origin of life |
Teaching at the Moscow University |
Epilogue |
Efraim Racker: 28 June 1913 to 9 September 1991 / G. SchatzChapter 5: |
A Life with the Metals of Life / B.G. MalmstromChapter 6: |
Introduction: the shaping of a bioinorganic chemist |
Early influences on my intellectual development |
A gymnasium with a university curriculum |
A book with a mission |
From gymnasium to college studies in the United States |
The graduate school years |
The beginnings of research |
Intellectual influences on a graduate student |
Enzyme research in Uppsala |
Metal-ion activation of enolase |
Uppsala friends |
Instructor in Minnesota |
Teaching and research |
A short army career |
'Docent' in Uppsala |
The embryo of an enzyme group |
An expanding research program |
An interlude in Utah |
The beginnings of oxidase research |
The end of the Uppsala period |
Visiting professor in California |
A bioinorganic course |
The transition from Uppsala to G oteborg |
Professor at Goteborg University |
A glimpse of the Swedish academic system of the 1960s |
The building of a new department |
A number of visitors |
My research 1964-93 |
Laccase and other blue copper proteins |
Three sabbaticals |
Early cytochrome oxidase investigations |
My collaboration with Harry Gray |
Electron transfer and proton pumping |
The Cu A site |
The Nobel Committee for Chemistry 1972-1988 |
The composition of the committee |
Some small reforms |
The happy life of a professor emeritus |
Mutants of bacterial cytochrome oxydases |
Cu A and PNA |
Acknowledgements |
Harland Goff Wood: An American Biochemist / R. Singleton, Jr.Chapter 7: |
Early years and education |
Affiliation with C. H. Werkman at Iowa State |
Graduate research |
Postdoctoral work |
The propionic acid cycle |
Early studies on propionic acid metabolism |
Expansion of the research project |
Discovery of the transcarboxylation reaction |
Isolation of the transcarboxylase enzyme |
Completion of the propionic acid cycle |
Conclusions |
Coda |
Fermentation balances / Appendix A: |
Fate has Smiled Kindly / S.V. PerryChapter 8: |
Early |
Preface to Volume 41 Contributors to this Volume |
Enemy Alien |
Kaj Linderstroslash;m-Lang (1896ndash;1959) / J. Schellman ; C. Schellman |
A late-blooming scientist |
The Carlsberg Laboratory |
Lang's scientific career |
Linderstroslash;m-Lang, the man |
Acknowledgements and references for further reading |
Strife and Hope in the Lives of a Scientist Couple / M. Barany ; K. Barany |
Years of 1939ndash;1945 |
The Szentndash;Gyorgyi Institute |
The Straub Institute |
The Weizmann Institute |
The Weber Institute |
Institute for Muscle Disease |
University of Illinois at Chicago |
Half a Century with TMV and Biophysics / M.A. Lauffer |
Beginnings |
The Princeton years |
The move to Pittsburgh |
The Virus Research Program |
The Biophysics Department |
The Lipoprotein Program |
Hydration |
Form and function |
Deaning |
Inactivation of viruses by X-rays |
Fort Dietrich |
Compliments |
The McCarthy era |
Whiskers |
Hydrodynamics |
The middle 1950s to the middle 1960s |
The education enterprise |
Motion in biological systems |
Entropy-driven processes in biology |
The meaning of entropy-driven processes |
Retired living |
The Initial Step in my Science Career / H. Fujita |
Prologue |
Getting a job at the Department of Fisheries |
Non-linear diffusion |
My stay in Leiden |
Moving to the United States |
Days on the Madison campus |
Fascination in Modeling Motifs / H. Kuhn |
1920s and 1930s |
Werner Kuhn and modeling polymer molecules |
Linus Pauling and attempts in quantum chemistry |
Niels Bohr and the branched pgr; electron systems |
Tests and refinements of the free electron model |
Coupled oscillator approach |
The 1950s and today |
Supramolecular machines |
Scheibe aggregates |
Copying at the molecular level |
Manipulating electron and proton motion |
Origin of life |
Erik Jorpes - A Pragmatic Physiological Chemist / V. Mutt ; M. Blomback |
Erik Jorpes' childhood and youth |
Jorpes as a grantee in America: nucleic acids, endocrine secretion of pancreas, secretin, insulin, and heparin |
Erik Jorpes and other studies by his colleagues in clinical medicine |
Other important research in the department |
Edman and protein characterization |
Viktor Mutt's recollections of Erik Jorpes in the research environment in 1944 |
Recollections of Margareta Blomback on the working environment in the 1950s and the early 1960s |
Erik Jorpes as historian and teacher |
Jorpes and the international research community |
Jorpes as a person |
Half a Century Between Carbohydrates and Proteins / N. Sharon |
Family and childhood in Poland |
Growing up in Palestine |
Choosing biochemistry as a profession |
How I started with carbohydrates |
Into protein biosynthesis |
Returning to carbohydrates |
Learning about enzyme mechanisms |
Back in the Laboratory for Carbohydrate Research |
Lysozyme, peptidoglycan and penicillin |
My first glycoprotein and first lectin |
Obscure proteins as markers for cancer cells |
Chemical and biological characterization of soybean agglutinin |
Enter peanut agglutinin |
A life-saving application |
Bacterial surface lectins and infectious disease |
Carbohydrates in anti-adhesion therapy |
Early evidence for innate immunity |
Atomic basis of carboh |
Preface to Volume 44 |
Contents |
Glucose Catabolism in Yeast and Muscle / James A. Barnett |
Abstract |
Glycolysis: The Pathway of Ethanolic Fermentation in Yeasts and Lactic Acid-Formation in Muscles |
Some Background: The 19th Century and After |
Some Remarkable Investigators |
Fermentation by Yeast Extracts |
The Role of Phosphates in Fermentation |
Harden's Finding that Phosphate Increases Fermentation |
The Equation for Fermentation and Harden and Young's Discovery of D-Fructose 1,6-Bisphosphate |
Isolation of Additional Hexose Phosphates of the Glycolytic Pathway |
Phosphate Bond Energy |
The Discovery of NAD and NADP |
The Formation of Glycerol in Fermentation |
Recognition of an Identical Glycolytic Pathway in Yeasts, Animals and Plants |
Neuberg's Theory of 1913 |
Embden's Pathway of 1933 |
Elucidating Some Enzymes of Glycolysis |
Hexokinase |
Glucose-6-Phosphate Isomerase |
6-Phosphofructokinase |
Triose Phosphate Isomerase and Fructose-Bisphosphate Aldolase |
Glyceraldehyde 3-Phosphate Dehydrogenase and Phosphoglycerate Kinase |
Phosphoglycerate Mutase |
Phosphopyruvate Hydratase ("Enolase") |
Pyruvate Kinase |
Pyruvate Decarboxylase |
Alcohol Dehydrogenase (ADH) |
l-Lactate Dehydrogenase |
The Main Respiratory Pathway |
The Tricarboxylic Acid Cycle |
"Active Acetate" |
Coenzyme A |
The Tricarboxylic Acid Cycle in Yeasts |
Membrane Impermeability |
The Concept of Oxidation |
Intracellular Oxidation |
Concepts of Biological Oxidations up to 1925 |
Cytochrome |
The Respiratory Chain: A Summary |
Conclusion |
Acknowledgments |
A Lifetime with Microbes / Georges N. Cohen |
L'Institut Pasteur de Paris |
Gif sur Yvette |
Back to the Pasteur Institute (1969-83) |
Wearing Two Hats / Guy Dirheimer |
The War Years, 1939-1945 |
Secondary School and University |
Starting Research at the CNRS in J.-P. Ebel's Lab |
Crossing Africa |
Inorganic Polyphosphates |
Military Service and Lysozyme |
Polyphosphates and RNAs |
Professor of Biochemistry |
Starting with tRNAs in Holley's Lab |
Countercurrent Distribution of tRNAs |
Starting Toxicology with Ricin |
Analogues of Nucleotides |
CNRS Commissions |
The Events of May 1968 |
Dean of the Faculty of Pharmacy |
Sequencing tRNAs |
Ricin Toxic Peptides |
Aminoacyl-tRNA Synthetases |
Specific Modifications of tRNAs: Lead and Carcinogens |
Building the IBMC |
Mitochondrial tRNAs |
Ricin, Final Episode |
tRNA Modification |
Continuing the Sequencing of tRNAs |
Yeast Mitochondrial tRNA Structures and the Genetic Code |
Workshops and Congresses |
FEBS Officer |
DNA Methylation |
Applied Research |
EST Congress in Strasbourg and EUROTOX |
Cloning and Sequencing of Aminoacyl-tRNA Synthetases Genes |
Teaching and Committees |
Reorganisation of the IBMC |
Toxicology of Madagascar Plants and Mushrooms |
Evolution of the IBMC |
Ochratoxine A |
FEBS Meeting 1999 in Nice |
President of FEBS |
Of Mice and Men - The Mx Connection / Jean Lindenmann |
By Way of Introduction |
From London via Zurich to Bern |
The A2G Saga, First Part |
The Second Chance |
A Case of Innate Resistance |
The A2G Saga, Second Part |
Putting Two and Two Together |
Gainesville |
A Foray into Mouse Genetics |
From Gainesville to Zurich |
Another Try at Genetics |
Back to Basics |
The Dawn |
Into Molecular Biology |
Discussion |
By Way of Closing |
An Unconventional Journey to Neuroscience / Richard Rodnight |
Early Years |
The Years as a Medical Laboratory Technician |
The Move into Research |
Higher Education |
Research at the Institute of Psychiatry |
Basic Research |
Teaching and Administrative Responsibilities in the Institute of Psychiatry |
The Years in Brazil |
The Final Move and Envoy |
Nikolai Vavilov: Life in the Cause of Science or Science at a Cost of Life / Elena S. Levina ; Vladimir D. Yesakov ; Lev L. Kisselev |
Abbreviations |
Brilliant Beginning |
Nikolai Vavilov: Nature Scientist, Leader and Organizer |
What the Archives Have Revealed |
Conflict between Nikolai Vavilov and Trofim Lyssenko |
Arrest and Death |
Index |
Life, luck and logic in biochemical research / F. LynenChapter 1: |
Memories of Heidelberg - and of other places / T. Wieland2: |
Stepping stones - building bridges / B. Witkop3: |
Recollections: Vacillation of a classical biochemist / E.J.M. Helmreich4: |
These are the moments when we live! From thunberg tubes and manometry to phone, fax and fedex / H. Beinert5: |
Chorismic acid and beyond / F. Gibson6: |