Molecular genetics of bacteria

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Molecular genetics of bacteria / Jeremy Dale

資料種別:: 図書
出版情報:: Chichester ; New York : Wiley, c1989
形態:: vii, 222 p. ; 23 cm
著者名:: Dale, Jeremy <DA03403648>
ISBN:: 9780471922094 [0471922099]
書誌ID:: BA07110907

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Molecular genetics of bacteria. 5th ed (: hbk ; : pbk)
Jeremy W. Dale and Simon F. Park , Wiley-Blackwell , 2010

書誌詳細

注記:

"A Wiley-Interscience publication."
Includes index

主題:

Genetic engineering; Microbial genetics; Molecular genetics

言語:

英語

目次情報:

Nucleic Acid Structure and Function / 1：

Structure of nucleic acids / 1.1：

DNA / 1.1.1：

Mutation and Variation

Regulation and Gene Expression / 1.1.2：

RNA

Genetics of Bacteriophages / 4：

Hydrophobic interactions / 5：

Plasmids

Gene Transfer / 1.1.4：

Different forms of the double helix

Genomic Plasticity: Movable Genes and Phase Variation / 7：

Supercoiling / 8：

Genetic Modification: Exploiting the Potential of Bacteria

Genetic Methods for Investigating Bacteria / 1.1.6：

Denaturation and hybridization

Gene Mapping to Genomics / 10：

Orientation of nucleic acid strands / Appendix A：

Further Reading

Abbreviations / 1.2：

Replication of DNA

Glossary / Appendix C：

Unwinding and rewinding / Appendix D：

Enzymes

Genes / 1.2.2：

Fidelity of replication: proof-reading

Standard Genetic Code / Appendix F：

Chromosome replication and cell division / Appendix G：

Bacterial Species

Index / 1.4：

DNA repair

Mismatch repair / 1.4.1：

Excision repair / 1.4.2：

Recombination (post-replication) repair / 1.4.3：

SOS repair / 1.4.4：

Gene expression / 1.5：

Transcription / 1.5.1：

Translation / 1.5.2：

Post-translational events / 1.5.3：

Gene organization / 1.6：

Variation and evolution / 2.1：

Fluctuation test / 2.1.1：

Directed mutation in bacteria? / 2.1.2：

Types of mutations / 2.2：

Point mutations / 2.2.1：

Conditional mutants / 2.2.2：

Variation due to larger scale DNA alterations / 2.2.3：

Extrachromosomal agents and horizontal gene transfer / 2.2.4：

Phenotypes / 2.3：

Restoration of phenotype / 2.4：

Reversion and suppression / 2.4.1：

Complementation / 2.4.2：

Recombination / 2.5：

Mechanisms of mutation / 2.6：

Spontaneous mutation / 2.6.1：

Chemical mutagens / 2.6.2：

Ultraviolet irradiation / 2.6.3：

Isolation and identification of mutants / 2.7：

Mutation and selection / 2.7.1：

Replica plating / 2.7.2：

Penicillin enrichment / 2.7.3：

Isolation of other mutants / 2.7.4：

Molecular methods / 2.7.5：

Regulation of Gene Expression

Gene copy number / 3.1：

Transcriptional control / 3.2：

Promoters / 3.2.1：

Terminators, attenuators and anti-terminators / 3.2.2：

Induction and repression: regulatory proteins / 3.2.3：

Attenuation: trp operon / 3.2.4：

Two-component regulatory systems / 3.2.5：

Global regulatory systems / 3.2.6：

Feast or famine and the RpoS regulon / 3.2.7：

Quorum sensing / 3.2.8：

Translational control / 3.3：

Ribosome binding / 3.3.1：

Codon usage / 3.3.2：

Stringent response / 3.3.3：

Regulatory RNA / 3.3.4：

Phase variation / 3.3.5：

Single-stranded DNA bacteriophages / 4.1：

oX174 / 4.1.1：

M13 / 4.1.2：

RNA-containing phages: MS2 / 4.2：

Double-stranded DNA phages / 4.3：

Bacteriophage T4 / 4.3.1：

Bacteriophage lambda / 4.3.2：

Lytic and lysogenic regulation of bacteriophage lambda / 4.3.3：

Restriction and modification / 4.4：

Complementation and recombination / 4.5：

Why are bacteriophages important? / 4.6：

Phage typing / 4.6.1：

Phage therapy / 4.6.2：

Phage display / 4.6.3：

Bacterial virulence and phage conversion / 4.6.4：

Some bacterial characteristics are determined by plasmids / 5.1：

Antibiotic resistance / 5.1.1：

Colicins and bacteriocins / 5.1.2：

Virulence determinants / 5.1.3：

Plasmids in plant-associated bacteria / 5.1.4：

Metabolic activities / 5.1.5：

Molecular properties of plasmids / 5.2：

Plasmid replication and control / 5.2.1：

Plasmid stability / 5.3：

Plasmid integrity / 5.3.1：

Partitioning / 5.3.2：

Differential growth rate / 5.3.3：

Methods for studying plasmids / 5.4：

Associating a plasmid with a phenotype / 5.4.1：

Classification of plasmids / 5.4.2：

Transformation / 6.1：

Conjugation / 6.2：

Mechanism of conjugation / 6.2.1：

The F plasmid / 6.2.2：

Conjugation in other bacteria / 6.2.3：

Transduction / 6.3：

Specialized transduction / 6.3.1：

General (homologous) recombination / 6.4：

Site-specific and non-homologous (illegitimate) recombination / 6.4.2：

Mosaic genes and chromosome plasticity / 6.5：

Insertion sequences / 7.1：

Structure of insertion sequences / 7.1.1：

Occurrence of insertion sequences / 7.1.2：

Transposons / 7.2：

Structure of transposons / 7.2.1：

Integrons / 7.2.2：

Mechanisms of transposition / 7.3：

Replicative transposition / 7.3.1：

Non-replicative (conservative) transposition / 7.3.2：

Regulation of transposition / 7.3.3：

Activation of genes by transposable elements / 7.3.4：

Mu: a transposable bacteriophage / 7.3.5：

Conjugative transposons and other transposable elements / 7.3.6：

Variation mediated by simple DNA inversion / 7.4：

Variation mediated by nested DNA inversion / 7.4.2：

Antigenic variation in the gonococcus / 7.4.3：

Phase variation by slipped strand mispairing / 7.4.4：

Phase variation mediated by differential DNA methylation / 7.4.5：

Strain development / 8.1：

Generation of variation / 8.1.1：

Selection of desired variants / 8.1.2：

Overproduction of primary metabolites / 8.2：

Simple pathways / 8.2.1：

Branched pathways / 8.2.2：

Overproduction of secondary metabolites / 8.3：

Gene cloning / 8.4：

Cutting and joining DNA / 8.4.1：

Plasmid vectors / 8.4.2：

Bacteriophage lambda vectors / 8.4.3：

Cloning larger fragments / 8.4.5：

Bacteriophage M13 vectors / 8.4.6：

Gene libraries / 8.5：

Construction of genomic libraries / 8.5.1：

Screening a gene library / 8.5.2：

Construction of a cDNA library / 8.5.3：

Products from cloned genes / 8.6：

Expression vectors / 8.6.1：

Making new genes / 8.6.2：

Other bacterial hosts / 8.6.3：

Novel vaccines / 8.6.4：

Other uses of gene technology / 8.7：

Metabolic pathways / 9.1：

Cross-feeding / 9.1.1：

Microbial physiology / 9.2：

Reporter genes / 9.2.1：

Lysogeny / 9.2.2：

Cell division / 9.2.3：

Motility and chemotaxis / 9.2.4：

Cell differentiation / 9.2.5：

Bacterial virulence / 9.3：

Wide range mechanisms of bacterial pathogenesis / 9.3.1：

Detection of virulence genes / 9.3.2：

Specific mutagenesis / 9.4：

Gene replacement / 9.4.1：

Antisense RNA / 9.4.2：

Taxonomy, evolution and epidemiology / 9.5：

Molecular taxonomy / 9.5.1：

Diagnostic use of PCR / 9.5.2：

Molecular epidemiology / 9.5.3：

Gene mapping / 10.1：

Conjugational analysis / 10.1.1：

Co-transformation and co-transduction / 10.1.2：

Molecular techniques for gene mapping / 10.1.3：

Gene sequencing / 10.2：

DNA sequence determination / 10.2.1：

Genome sequencing / 10.2.2：

Comparative genomics / 10.2.3：

Bioinformatics / 10.2.4：

Physical and genetic maps / 10.3：

Deletions and insertions / 10.3.1：

Transposon mutagenesis / 10.3.2：

Site-directed mutagenesis / 10.3.3：

Analysis of gene expression / 10.4：

Transcriptional analysis / 10.4.1：

Translational analysis / 10.4.2：

Systematic analysis of gene function / 10.4.3：

Conclusion / 10.5：

Nucleic Acid Structure and Function / 1：

Structure of nucleic acids / 1.1：

DNA / 1.1.1：

Mutation and Variation

Regulation and Gene Expression / 1.1.2：

RNA

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