Combinatorial chemistry and molecular diversity in drug discovery

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Combinatorial chemistry and molecular diversity in drug discovery / edited by Eric M. Gordon and James F. Kerwin., Jr

資料種別:

図書

出版情報:

New York : Wiley, 1998

形態:

xxiv, 516 p. ; 24 cm

著者名:

ISBN:

9780471155188 [0471155187]

書誌ID:

BA37941418

子書誌情報

フルテキスト

所蔵情報

他の版・巻

書誌詳細

注記:

"A Wiley-Liss publication."
Includes bibliographical references and index

主題:

Combinatorial chemistry; Drugs--Design

言語:

英語

目次情報:

Combinatorial Chemistry and Molecular Diversity: An Introduction

Historical Overview of the Developing Field of Molecular Diversity / J. Chabala, et al.

Solid-Phase Peptide Synthesis, Lead Generation, and Optimization / B. Seligman, et al.

Oligonucleotide Libraries as a Source of Molecular Diversity / H.-Y. Mei, et al.

Small Molecular Libraries

Protease Inhibitor Libraries / D. Patel ; D. Campbell

Scaffolds for Small Molecule Libraries / M. Pavia

Encoded Combinatorial Chemistry / J. Jacobs ; Z.-J. Ni

Parallel Organic Synthesis in Array Format / S. Hall

Automation, Analytical, and Computational Methods

Automation of Combinatorial Chemistry for Large Libraries / M. Needels ; J. Sugarman

Quantifying Diversity / Y. Martin, et al.

Biological Diversity

Protein Scaffolds for Peptide Libraries / R. Hoess

Screening

Strategies for Screening Combinatorial Libraries / B. Beutel

Combinatorial Drug Screening and Development

Combinatorial Technologies: Prospects and Future Issues / J. Kerwin

Appendix

Index

Combinatorial Chemistry and Molecular Diversity: An Introduction

Historical Overview of the Developing Field of Molecular Diversity / J. Chabala, et al.

Solid-Phase Peptide Synthesis, Lead Generation, and Optimization / B. Seligman, et al.

Oligonucleotide Libraries as a Source of Molecular Diversity / H.-Y. Mei, et al.

Small Molecular Libraries

Protease Inhibitor Libraries / D. Patel ; D. Campbell

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