The cellular basis of biochemistry / 1: |
Types of living cells |
The structure of prokaryotic and eukaryotic cells |
Endocytosis and exocytosis through the plasma membrane |
The nucleus |
Mitochondria |
Lysosomes |
Peroxisomes |
The endoplasmic reticulum |
The cytoskeleton |
Subcellular fractionation |
The microsome fraction |
Marker enzymes |
Metabolic functions of organelles |
An introduction to proteins and peptides / 2: |
The role of amino acids in the cell |
Structure of amino acids |
Asymmetry in biochemistry |
Ionic properties of amino acids |
Peptide structure and the peptide bond |
Ionic properties of peptides |
Purification of proteins and determination of relative molecular mass |
The determination of the amino acid sequence of proteins |
Protein structural hierarchies |
Protein denaturation and renaturation |
Peptides, structure and biological activity |
Nucleic acids and protein synthesis / 3: |
Introduction: Replication, transcription and translation |
Nucleic acid structure and synthesis |
Other enzymes with DNA synthetic activity |
Biosynthesis of proteins: translation |
Molecular cell biology |
Recombinant DNA (genetic engineering) |
Protein structure and function with hemoglobin as an example / 4: |
The properties of proteins |
The folding of globular proteins |
General principles of protein folding |
Structure and properties of myoglobin and hemoglobin |
Proteins: specialized functions / 5: |
Plasma proteins |
The immune system and the immunoglobulins |
Proteins of molecular motors |
The structure and function of enzymes / 6: |
The properties of enzymes |
Enzyme kinetics |
Metabolic regulation and control |
Enzyme phosphorylation and dephosphorylation |
Second messengers |
Allosteric properties of enzymes |
Metabolic control analysis |
Genetic diversity of enzymes |
Coenzymes and water-soluble vitamins |
Carbohydrates: structures and interconversions / 7: |
Monosaccharides and disaccharides |
Polysaccharides |
Interconversions of monosaccharides |
Detoxification mechanisms |
Nitrogen metabolism / 8: |
Protein breakdown and excretion of nitrogen |
The supply of amino acids |
Catabolism of essential amino acids and the formation of adrenaline, histamine, thyroxine and serotonin |
The biosynthesis and metabolism of heme |
Oxidative catabolism of glucose and fatty acids / 9: |
[beta]-Oxidation and glycolysis |
The citric acid cycle |
The electron transport chain |
Oxidative phosphorylation |
Other mitochondrial topics |
Carbohydrate and lipid metabolism in the fasting state / 10: |
Metabolism in the fasting state |
Glycogen and its degradation |
Gluconeogenesis |
Ketone body formation and utilization |
Control of the blood glucose in health and disease |
Carbohydrate and lipid metabolism in the absorptive state / 11: |
The process of absorption |
Glycogenesis |
Lipogenesis |
Plasma lipoproteins, cholesterol metabolism and atherosclerosis / 12: |
Plasma lipoproteins and cholesterol metabolism |
The action of hormones and other effectors in regulating glycogen and glucose metabolism, ketogenesis and lipogenesis / 13: |
Whole-body interactions |
The regulation of glycogen metabolism |
Regulation of glycolysis and gluconeogenesis |
Regulation of lipid metabolism |
Phospholipids, other lipid substances and complex carbohydrates / 14: |
Phospholipids |
Lipid-soluble vitamins |
Other lipid compounds |
Complex carbohydrates |
Biomembranes, receptors and signal transduction / 15: |
The basis of membrane structure |
Structure of the phospholipid bilayer |
Membrane receptors |
G proteins |
Cell signalling systems |
Receptor traffic |
Membrane transport |
Cell adhesion |
The post-genomic era and its impact on the future of biochemistry and molecular biology / 16: |
Introduction |
Bioinformatics |
Apoptosis |
Telomeres and telomerases |
Growth control and cancer |
Further Reading |
Index |
The cellular basis of biochemistry / 1: |
Types of living cells |
The structure of prokaryotic and eukaryotic cells |
Endocytosis and exocytosis through the plasma membrane |
The nucleus |
Mitochondria |