| Introduction / Part I： |
| Chemistry and Biology -- Historial and Philosophical Aspects / Gerhard Quinkert |
| Using Small Molecules To Explore Biology / Part II： |
| Using Small Molecules to Unravel Biological Mechanisms / Tarun Kapoor |
| Using Natural Products to Unravel Cell Biology / Craig Crews |
| Engineering Control Over Protein Function Using Chemistry / Kevan Shokat |
| Controlling Protein Function by Caged Compounds / Carsten Schultz |
| Transcription Control by Small-Molecules / John Koh |
| Controlling Protein-Protein Interactions / Virginia Cornish ; Columbia University) Controlling Protein-Protein Interactions Using Chemical Inducers and Disrupters of Dimerization ; Tim Clackson |
| Protein Secondary Structure Mimetics as Modulators of Protein-Protein and Protein-Ligand Interactions / Andrew Hamilton |
| Expanding the Genetic Code / Masahiko Sisido |
| Discovering Small Molecule Probes For Biological Mechanisms / Part III： |
| Forward Chemical Genetics / Stuart Schreiber ; Steve Haggarty |
| Reverse Chemical Genetics -- An Important Strategy for the Study of Protein Function in Chemical and Drug Discovery / Herbert Waldmann |
| Chemical Biology and Enzymology: Protein Phosphorylation as a Case Study / Phil Cole |
| Chemical Strategies for Activity-based Proteomics / Ben Cravatt |
| The Biarsenical Tetracysteine Protein Tag: Chemistry and Biological Applications / Steve Adams |
| Chemical Approaches to Exploit Fusion Proteins for Functional Studies / Kai Johnsson |
| Expanding The Scope Of Chemical Synthesis / Part IV： |
| Diversity-oriented Synthesis / Derek Tan |
| Combinatorial Biosynthesis of Polyketides and Nonribosomal Peptides / Chaitan Khosla |
| Expressed Protein Ligation / Tom Muir |
| Chemical Synthesis of Proteins and Large Bioconjugates / Phil Dawson |
| New Methods for Protein Bioconjugation / Matt Francis |
| The Search for Chemical Probes to Illuminate Carbohydrate Function / Laura Kiessling |
| Chemical Clydomics as Basis for Drug Discovery / Peter Seeberger |
| The Bicyclid Depsipeptide Family of Histone Deacetylase / A. Ganesan |
| Chemical Informatics / Part V： |
| Wombat and Wombat-Pk / Paul Clemons |
| Bioactivity Databases for Lead and Drug Discovery / Tudor Oprea |
| Drug discovery / Part VI： |
| Managerial Challenges in Implementing Chemical Biology Platforms / Frank Douglas |
| The Molecular Basis of Predicting Druggability / Andrew Hopkins ; Pfizer) |
| The Target Family Approach / Peter Nestler ; Sanofi-Aventis) |
| Chemical Biology of Kinases Studied by NMR Spectroscopy / Harald Schwalbe |
| The Nuclear Receptor Superfamily and Drug Discovery / Kenneth Pearce |
| The GPCR-7TM Receptor Target Family / Edgar Jacoby |
| Drugs Targeting Protein-Protein Interactions / Patrick Chene ; Novartis) |
| Systems Biology / Part VII： |
| Prediction of ADMET properties / Ulf Norinder ; AstraZeneca) |
| Systems Biology of the JAK-STAT Signaling Pathway / Jens Timmer |
| Modeling Intracellular Signal Transduction Processes / Jason Haugh |
| Genome-wide Gene Expression and Application to the Analysis of T-Cell Subsets in Inflammatory Diseases / Lars Rogge |
| Scanning the Proteome for Targets of Organic Small Molecules Using Bifunctional Receptor Ligands / Nikolai Kley |
| Outlook / Part VIII： |
| Introduction / Part I： |
| Chemistry and Biology -- Historial and Philosophical Aspects / Gerhard Quinkert |
| Using Small Molecules To Explore Biology / Part II： |
| Using Small Molecules to Unravel Biological Mechanisms / Tarun Kapoor |
| Using Natural Products to Unravel Cell Biology / Craig Crews |
| Engineering Control Over Protein Function Using Chemistry / Kevan Shokat |
