Untangling the double helix : DNA entanglement and the action of the DNA topoisomerases

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Untangling the double helix : DNA entanglement and the action of the DNA topoisomerases / James C. Wang

資料種別:: 図書
出版情報:: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, c2009
形態:: xi, 233 p. ; 23 cm
著者名:: Wang, James C. <DA05292796>
ISBN:: 9780879698799 [0879698799] (: pbk)
9780879698638 [0879698632] (: hard)
書誌ID:: BA90183615

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注記:

Includes bibliographical references and index

主題:

蛋白質

言語:

英語

目次情報:

Preface

An Insuperable Problem / 1：

Nature's Solutions: The DNA Topoisomerases / 2：

Breaking a DNA Strand and Holding on to the Broken Ends / 3：

A Magic Swivel / 4：

Moving One DNA Double Helix through Another / 5：

Real-Time Viewing of the DNA Topoisomerases in Action / 6：

Manifestations of DNA Entanglement: Replication and Recombination / 7：

Manifestations of DNA Entanglement: Gene Expression / 8：

Beyond DNA Entanglement: New Twists on an Old Theme / 9：

From Nature's Battlefields to the Clinical Wards / 10：

Identification of the Covalent Intermediates in Topoisomerase-Catalyzed Reactions / Appendix 1：

Catalysis of DNA Breakage and Rejoining by DNA Topoisomerases / Appendix 2：

Index

Preface

An Insuperable Problem / 1：

Nature's Solutions: The DNA Topoisomerases / 2：

Breaking a DNA Strand and Holding on to the Broken Ends / 3：

A Magic Swivel / 4：

Moving One DNA Double Helix through Another / 5：

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