Preface |
An Insuperable Problem / 1: |
Nature's Solutions: The DNA Topoisomerases / 2: |
Breaking a DNA Strand and Holding on to the Broken Ends / 3: |
A Magic Swivel / 4: |
Moving One DNA Double Helix through Another / 5: |
Real-Time Viewing of the DNA Topoisomerases in Action / 6: |
Manifestations of DNA Entanglement: Replication and Recombination / 7: |
Manifestations of DNA Entanglement: Gene Expression / 8: |
Beyond DNA Entanglement: New Twists on an Old Theme / 9: |
From Nature's Battlefields to the Clinical Wards / 10: |
Identification of the Covalent Intermediates in Topoisomerase-Catalyzed Reactions / Appendix 1: |
Catalysis of DNA Breakage and Rejoining by DNA Topoisomerases / Appendix 2: |
Index |
Preface |
An Insuperable Problem / 1: |
Nature's Solutions: The DNA Topoisomerases / 2: |
Breaking a DNA Strand and Holding on to the Broken Ends / 3: |
A Magic Swivel / 4: |
Moving One DNA Double Helix through Another / 5: |