by Caroline F. Ware, K.M. Panikkar, and J.M. Romein
出版情報:
London : Published for the International Commission for a History of the Scientific and Cultural Development of Mankind by Allen & Unwin, 1966 2 v. ; 24 cm
by Luigi Pareti ; assisted by Paolo Brezzi and Luciano Petech ; translated from the Italian by Guy E.F. Chilver and Sylvia Chilver
出版情報:
London : Published for the International Commission for a History of the Scientific and Cultural Development of Mankind by Allen & Unwin, 1965 3 v. ; 24 cm
Conference of the International Society for the Study of Time ; Fraser, J. T. ; Haber, F. C. ; Müller, G. H. (Gert Heinz), 1923- ; Lawrence, Nathaniel ; Park, David Allen, 1919-
出版情報:
Berlin ; New York : Springer-Verlag, 1972- v. ; 25 cm
[v. 1]. Proceedings of the first conference of the International Society for the Study of Time, Oberwolfach (Black Forest), West Germany / edited by J.T. Fraser, F.C. Haber, G.H. Müller
2. Proceedings of the Second conference of the International Society for the Study of Time, Lake Yamanaka, Japan / edited by J.T. Fraser and N. Lawrence
3. Proceedings of the Third held in 1976 at Alpbach, Austria
4. Papers from Fourth conference of the International Society for the Study of Time, Alpbach-Austria / edited by J.T. Fraser, N. Lawrence, D. Park
[v. 1]. Proceedings of the first conference of the International Society for the Study of Time, Oberwolfach (Black Forest), West Germany / edited by J.T. Fraser, F.C. Haber, G.H. Müller
2. Proceedings of the Second conference of the International Society for the Study of Time, Lake Yamanaka, Japan / edited by J.T. Fraser and N. Lawrence
3. Proceedings of the Third held in 1976 at Alpbach, Austria
Contribution of Membrane Mucins to Tumor Progression Through Modulation of Cellular Growth Signaling Pathways / Kermit L. Carraway III ; Melanie Funes ; Heather C. Workman ; Colleen Sweeney1:
Mucin Structure, Function, and Involvement in Tumor Progression / I:
MUC1 Contributions to Tumor Cell Growth Signaling / II:
MUC4 Contributions to Tumor Cell Growth Signaling / III:
Inhibition of Signaling by Mucins / IV:
Perspectives / V:
References
Regulation of the Epithelial Na[superscript +] Channel by Peptidases / Carole Planes ; George H. Caughey2:
Introduction
ENaC Regulation by Peptidases: In Vitro and Biochemical Evidence
ENaC Regulation by Peptidases: In Vitro Evidence
Advances in Defining Regulators of Cementum Development and Periodontal Regeneration / Brian L. Foster ; Tracy E. Popowics ; Hanson K. Fong ; Martha J. Somerman3:
Question 1. What Are the Unknowns That Must Be Considered in Order to Replicate the Enamel (Crown) and How Do the Proteins Involved in Crown Development Relate to Root Development?
Question 2. What Do We Know About the Cells Required for Periodontal Development and Regeneration?
Question 3. What Genes and Associated Proteins Are Important for Root/Periodontal Tissue Formation?
Conclusions and Future Directions
Acknowledgments
Anabolic Agents and the Bone Morphogenetic Protein Pathway / I. R. Garrett4:
Bone Metabolism
The BMP Pathway and Bone Anabolic Therapies
The Role of Mammalian Circadian Proteins in Normal Physiology and Genotoxic Stress Responses / Roman V. Kondratov ; Victoria Y. Gorbacheva ; Marina P. Antoch5:
Circadian Rhythms and the Organization of the Mammalian Circadian System
Molecular Organization of the Circadian Oscillator in Mammals
Human Disorders Associated with Altered Function of the Circadian System
Pathologies and Developmental Defects in Circadian Mutant Mice
Circadian Control of the Organism's Response to Genotoxic Stress / VI:
Circadian Proteins as Targets for Therapeutic Intervention / VII:
Autophagy and Cell Death / Devrim Gozuacik ; Adi Kimchi6:
Description of Programed Cell Death Morphologies
Autophagic Cell Death
Autophagy and Autophagic Cell Death Regulatory Mechanisms
Autophagy-Apoptosis Crosstalks
Survival Versus Death Aspects of Autophagy
Conclusions
Index
Contents of Previous Volumes
Similarities Between Angiogenesis and Neural Development: What Small Animal Models Can Tell Us / Chapter 1:
Junction restructuring and spermatogenesis: the biology, regulation, and implication in male contraceptive development / Chapter 2:
Substrates of the Methionine Sulfoxide Reductase System and Their Physiological Relevance / Chapter 3:
Organic anion transporting polypeptides at the blood-brain and blood-cerebrospinal fluid barriers / Chapter 4:
Mechanisms and evolution of environmental responses in Caenorhabditis elegans / Chapter 5:
Pathophysiology of the blood-brain barrier: animal models and methods / Chapter 7:
Genetic manipulation of megakaryocytes to study platelet function / Chapter 8:
Genetics and Epigenetics of the Multifunctional Protein CTCF / Chapter 9:
BMP Signaling in the Cartilage Growth Plate / Robert Pogue ; Karen Lyons
Signaling Pathways Regulating Chondrogenesis
Overview of the BMP Signaling Pathway
Regulation of TGF-[Beta]/BMP Signaling
Expression of TGF-[Beta] Superfamily Members, Their Receptors, and Inhibitors in Precartilaginous and Cartilaginous Elements
TGF-[Beta]s and BMPs in Chondrogenesis
Downstream Effectors of BMP Signaling: Smads and p38
Interactions with Other Signaling Pathways / VIII:
The CLIP-170 Orthologue Bik1p and Positioning the Mitotic Spindle in Yeast / Rita K. Miller ; Sonia D'Silva ; Jeffrey K. Moore ; Holly V. GoodsonIX:
Structure of the Bik1 Protein
Bik1p Interactions with Other Proteins
Phenotypes and Activities
Role of Bik1p in Spindle Positioning
Models for Plus-End Binding
Regulation of CLIP-170 and Bik1p by Phosphorylation
Bik1p at the Kinetochore
Bik1p in Genomic Studies
Concluding Remarks and Perspective / X:
Aggregate-Prone Proteins Are Cleared from the Cytosol by Autophagy: Therapeutic Implications / Andrea Williams ; Luca Jahreiss ; Sovan Sarkar ; Shinji Saiki ; Fiona M. Menzies ; Brinda Ravikumar ; David C. Rubinsztein
Proteinopathies
Intracytoplasmic Aggregate-Prone Proteins Are Cleared by Autophagy
Autophagy Induction Has Additional Antiapoptotic Consequences
A New mTOR-Independent Autophagy Pathway
A Protective Role for Aggregates: Autophagy Upregulation
Wnt Signaling: A Key Regulator of Bone Mass / Roland Baron ; Georges Rawadi ; Sergio Roman-Roman
The Wnt Signaling Pathway
LRP5 and -6: Structure and Function
Human Genetic Evidence for the Role of Wnt Signaling in Bone Metabolism
How Is the HBM Mutation Constitutively Activating LRP5 and Wnt Signaling?
Mouse Genetics Confirms the Essential Role of the Wnt/[Beta]-Catenin Pathway in Bone
How Is Wnt Signaling Affecting Bone Homeostasis?
Effects of Wnts on Osteoblasts
Is the Wnt Pathway the Final Common Pathway of Bone Morphogens?
Is Wnt Signaling the Pathway Linking Mechanosensing to Bone Remodeling?
Pharmacological Manipulation of Wnt Signaling in Bone / XI:
Conclusion and Perspectives / XII:
Eukaryotic DNA Replication in a Chromatin Context / Angel P. Tabancay, Jr. ; Susan L. Forsburg
Chromatin Structure Regulates Access to the DNA
Replication Origins and Origin-Binding Proteins
Assembly of the Prereplication Complex on Chromatin
Origin Activation and Replication
Replication Elongation Through Chromatin
The Regulatory Network Controlling the Proliferation-Meiotic Entry Decision in the Caenorhabditis elegans Germ Line / Dave Hansen ; Tim Schedl
Temporal and Spatial Pattern of Proliferation and Initiation of Meiotic Development
Summary of the Core Regulatory Pathway Controlling the Proliferation-Meiotic Development Decision
Control of the Adult Pattern of Proliferation and Meiotic Entry
Regulation of the Activity of the GLD-1 and GLD-2 Pathways
Additional Components and Pathways Regulating the Proliferation-Meiotic Entry Decision
Regulation of Angiogenesis by Hypoxia and Hypoxia-Inducible Factors / Michele M. Hickey ; M. Celeste Simon7:
Mechanisms of Angiogenesis
The Hypoxia-Inducible Factor Family
The Role of HIF in Developmental Angiogenesis
The Role of HIF in Adult Tissues
HIF and Ischemic Injury
HIF and Cancer
Maternal Cytoplasmic Factors for Generation of Unique Cleavage Patterns in Animal Embryos / H. Nishida ; J. Morokuma ; T. Nishikata
Multiple Endo -1,4-b-d-glucanase (Cellulase) Genes in Arabidopsis / E. Del Campillo
The Anterior Margin of the Mammalian Gastrula: Comparative and Phylogenetic Aspects of Its Role in Axis Formation and Head Induction / C. Viebahn
The Other Side of the Embryo: An Application of the Non-D Quadrants in Leech Embryos / D.A. Weisblat ; F.Z. Huang ; D.E. Isaksen ; N.-J.L. Liu ; P. Chang
Sperm Nuclear Activation During Fertilization / S.J. Wright
Fibroblast Growth Factor Signaling Regulates Growth and Morphogenesis at Multiple Steps During Brain Development / F.M. Vaccarino ; M.L. Schwartz ; R. Raballo ; J. Rhee ; R. Lyn-Cook
Epigenetic Modification and Imprinting of the Mammalian Genome During Development / K.E. Latham
A Comparison of Hair Bundle Mechanoreceptors in Sea Anemones and Vertebrate Systems / G.M. Watson ; P. Mire
Development of Neural Crest in Xenopus / R. Mayor ; R. Young ; A. Vargas
Cell Determination and Transdetermination in Drosophila Imaginal Discs / G. Schubiger ; L. Maves
Cellular Mechanisms of Wingless/Wnt Signal Transduction / A. Bejsovec ; H. Dierick
Seeking Muscle Stem Cells / J.B. Miller ; L. Schaefer ; J.A. Dominov
Neural Crest Diversification / A.K. Groves ; M. Bronner-Fraser
Genetic, Molecular, and Morphological Analysis of Compound Leaf Development / T. Goliber ; S. Kessler ; J-J Chen ; G. Bharathan ; N. Sinha
Subject Index
Pattern Formation in Zebrafish: Fruitful Liaisons Between Embryology and Genetics / L. Solnica-Krezel
Molecular and Cellular Basis of Pattern Formation During Vertebrate Limb Development / J.K. Ng ; K. Tamura ; D. Busher ; J.C. Izpisua-Belmonte
Wise, Winsome, or Weird? Mechanisms of Sperm Storage in Female Animals / D.M. Neubaum ; M.F. Wolfner
Developmental Genetics of C. elegans Sex Determination / P.E. Kuwabara
Petal and Stamen Development / V.F. Irish
Gonadotropin-Induced Resumption of Oocyte Meiosis and Meiosis-Activating Sterols, MAS / C.Y. Anderson ; M. Baltsen ; A.G. Byskov
Contributors
Contribution of Membrane Mucins to Tumor Progression Through Modulation of Cellular Growth Signaling Pathways / Kermit L. Carraway III ; Melanie Funes ; Heather C. Workman ; Colleen Sweeney1:
Mucin Structure, Function, and Involvement in Tumor Progression / I: