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1.

図書
図書
1. Protein structural analysis, folding and design (: Japan)
edited by Masahiro Hatano
出版情報: Tokyo : Japan Scientific Societies Press , Amsterdam : Elsevier, 1990  viii, 237 p. ; 24 cm
2.

図書
図書
2. Advances in gene technology : protein engineering and production : proceedings of the 1988 Miami Bio/Technology Winter Symposium, Miami, Florida, USA, February 8-12, 1988
edited by Keith Brew ... [et al.]
出版情報: Oxford : IRL, c1988  xxi, 240 p. ; 28 cm
シリーズ名: ICSU short reports ; v. 8
3.

図書
図書
3. Concepts in protein engineering and design : an introduction
editors, Paul Wrede, Gisbert Schneider
出版情報: Berlin ; New York : W. de Gruyter, 1994  xviii, 378 p. ; 25 cm
4.

図書
図書
4. Peptide and protein design for biopharmaceutical applications (: [hbk])
editor, Knud J. Jensen
出版情報: West Sussex : Wiley, 2009  xii, 294, [6] p. ; 24 cm
目次情報: 続きを見る
List of Contributors
Preface
Introduction / Knud J. Jensen1：
Computational Approaches in Peptide and Protein Design: An Overview / Gregory V. Nikiforovicb ; Garland R. Marshall2：
Basics and Tools / 2.1：
The Importance of Computational Approaches / 2.2.1：
Tools and Procedures: Force Fields and Sampling / 2.2.2：
Computational Study of Cyclopentapeptide Inhibitors of CXCR4 / 2.3：
The 3D Pharmacophore Model for FC131 / 2.3.1：
A 3D Model of the TM Region of CXCR4 / 2.3.2：
Docking of FC131 to CXCR4 / 2.3.3：
Acknowledgements
References
Aspects of Peptidomimetics / Veronique Maes ; Dirk Tourwé3：
Modified Peptides / 3.1：
Pseudopeptides / 3.3：
Secondary Structure Mimics (Excluding Turn Mimics) / 3.4：
?-strand Mimetics / 3.4.1：
Helix Mimetics / 3.4.2：
Examples of Peptidomimetics / 3.5：
Conclusion / 3.6：
Design of Cyclic Peptides / Oliver Demmer ; Andreas O. Frank ; Horst Kessler4：
Pharmaceutical Research Today / 4.1：
General Advantages of Cyclic Peptide Structures / 4.1.2：
Examples of Cyclic Peptides of Medicinal Interest / 4.1.3：
General Considerations / 4.1.4：
Peptide Cyclization / 4.2：
Possibilities of Peptide Cyclization / 4.2.1：
Synthesis of Cyclic Peptides / 4.2.2：
Chemical Modifications of Cyclic Peptides / 4.2.3：
Concluding Remarks / 4.2.4：
Conformation and Dynamics of Cyclic Peptides / 4.3：
Reductions in Conformational Space / 4.3.1：
Conformational Arrangements in Cyclic Structures / 4.3.2：
Flexibility of Cyclized Scaffolds / 4.3.3：
Experimental Structure Characterization / 4.3.4：
Concepts in the Rational Design of Cyclic Peptides / 4.4：
The Influence of Amino Acid Composition / 4.4.1：
The Dunitz-Waser Concept / 4.4.2：
The Spatial Screening Technique / 4.4.3：
General Strategy for Finding Active Hits / 4.4.4：
Examples of Cyclic Peptides as Drug Candidates / 4.5：
Cilengitide as Integrin Inhibitor / 4.5.1：
CXCR4 Antagonists / 4.5.2：
Sandostatin and the Veber-Hirschmann Peptide as Examples of Rational Design / 4.5.3：
Carbohydrates in Peptide and Protein Design / Jesper Brask4.6：
Configurational and Conformational Properties of Carbohydrates / 5.1：
Carbohydrates in Peptidomimetics / 5.3：
Glycopeptides / 5.4：
Carbohydrates as Scaffolds in the Design of Nonpeptide Peptidomimetics / 5.5：
Sugar Amino Acids / 5.6：
Cyclodextrin-Peptide Conjugates / 5.7：
Carboproteins: Protein Models on Carbohydrate Templates / 5.8：
De Novo Design of Proteins / 5.9：
Secondary Structure Elements / 6.1：
The ?-helix / 6.2.1：
The ?-sheet / 6.2.2：
Loops, Turns and Templates / 6.2.3：
Assembling a Specified Tertiary Structure from Secondary Structural Elements / 6.3：
Computational Methods / 6.3.1：
Coiled Coils / 6.3.2：
?-helical Bundles / 6.3.3：
Fluorous Interactions / 6.3.4：
Additional Topics / 6.3.5：
Proteins on Templates / 6.4：
Foldamers / 6.5：
Biopharmaceutical Applications of De Novo Design / 6.6：
?-helical Structures in Biopharmaceutical Applications / 6.6.1：
Foldamers in Biopharmaceutical Applications / 6.6.2：
Design of Insulin Variants for Improved Treatment of Diabetes / Thomas Hoeg-Jensen7：
Diabetes Management and the Need for Insulin Engineering / 7.1：
Insulin Structure / 7.3：
Prolonged-acting Insulin Solids / 7.4：
Prolonged-acting Insulin Solutions / 7.5：
Fast-acting Insulins / 7.6：
Glucose-sensitive Insulin Preparations / 7.7：
Alternative Insulin Delivery / 7.8：
Insulin Mimetics / 7.9：
Pushing the Limits of Insulin Engineering / 7.10：
Index / 7.11：
List of Contributors
Preface
Introduction / Knud J. Jensen1：
5.

図書
図書
5. Phage display as a tool for synthetic biology (: pbk)
Santina Carnazza and Salvatore Guglielmino
出版情報: NewYork : Nova Science Publishers, 2010  ii, 79 p. ; 23 cm
目次情報: 続きを見る
Synthetic Biology Applications in Nanobiotechnology
The "Never Born" Proteins
Protein Engineering & Directed Evolution
In Vitro & Biological Display Technologies
Phage Display for Directed Molecular Evolution
Antibody Phage
Phage as Bioselective Probes
Phage-Derived Nanomaterials
Phage Perspectives in Nanobiotechnology
Index
Synthetic Biology Applications in Nanobiotechnology
The "Never Born" Proteins
Protein Engineering & Directed Evolution
6.

図書
図書
6. Protein engineering
editors, Dale L. Oxender, C. Fred Fox
出版情報: New York : Liss, c1987  xvii, 365 p. ; 27 cm
シリーズ名: Tutorials in molecular and cell biology
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