Contributors |
Preface |
Previous Volumes in Series |
Discovery of the Aquaporins and Their Impact on Basic and Clinical Physiology / Peter Agre ; Mario J. Borgnia ; Masato Yasui ; John D. Neely ; Jennifer Carbrey ; David Kozono ; Eric Beitz ; Jason Hoffer ; Virginia Leitch ; Landon S. KingChapter 1: |
Pre-Aquaporin Era / I.: |
The First Recognized Water Channel Protein / II.: |
Other Mammalian Aquaporins / III.: |
Nonmammalian Homologs / IV.: |
Perspective / V.: |
References |
The Aquaporin Superfamily: Structure and Function / Henning Stahlberg ; Bernard Heymann ; Kaoru Mitsuoka ; Yoshinori Fuyijoshi ; Andreas EngelChapter 2: |
Introduction |
Two-Dimensional Crystallization of Membrane Proteins |
Electron Crystallography |
Atomic Force Microscopy |
AQP1, The Erythrocyte Water Channel |
AQP0: The Major Intrinsic Protein of Lens Fiber Cells / VI.: |
Water Channel of Escherichia coli: AqpZ / VII.: |
Glycerol Channel of Escherichia coli: GlpF / VIII.: |
Comparison of the High-Resolution Projection Structures of GlpF and AQP1 / IX.: |
Conclusion and Perspectives / X.: |
Physiological Roles of Aquaporins in the Kidney / Mark A. Knepper ; Soren Nielsen ; Chung-Lin ChouChapter 3: |
Water Transport along the Renal Tubule |
Water Permeability along the Renal Tubule |
Aquaporin-1 Facilitates Isoosmotic Fluid Transport in Proximal Tubule |
Aquaporin-1 Allows Osmotic Equilibration in the Thin Descending Limb of Henle Despite Rapid Flow of Tubule Fluid |
Aquaporin-1 Allows Osmotic Equilibration in the Descending Vasa Recta |
Aquaporins Provide Molecular Targets for Regulation of Water Transport in the Renal Collecting Duct |
Pathophysiology of Renal Aquaporins / Tae-Hwan Kwon ; Henrik Hager ; David Marples ; Jorgen FrokiaerChapter 4: |
Inherited NDI and CDI |
Acquired NDI |
Urinary Concentrating Defects |
States of Water Retention |
Conclusions |
Genetic and Biophysical Approaches to Study Water Channel Biology / A. S. Verkman ; Baoxue Yang ; William R. Skach ; Alok Mitra ; Yuanlin Song ; Geoffrey T. Manley ; Tonghui MaChapter 5: |
Lessons from Aquaporin Knockout Mice |
Biophysical Analysis of Aquaporin Function |
Aquaporin Structure and Function |
New Directions in Aquaporin Physiology and Biophysics |
Trafficking of Native and Mutant Mammalian MIP Proteins / Peter M. T. Deen ; Dennis BrownChapter 6: |
Normal Routing of MIP Proteins |
Disturbed Trafficking of MIP Proteins |
Aquaporins of Plants: Structure, Function, Regulation, and Role in Plant Water Relations / Maarten J. Chrispeels ; Raphael Morillon ; Christophe Maurel ; Patricia Gerbeau ; Per Kjellbom ; Ingela JohanssonChapter 7: |
The Transpiration Stream |
Water Movement in and between Living Tissues |
Molecular Characteristics and Transport Properties of Plant Aquaporins |
Subcellular Location of Plant Aquaporins |
What Do the Water and Solute Transport Properties of Membranes Tell Us about the Aquaporins in Those Membranes? |
The Multiple Roles of Aquaporins: How to Link Water Transport Properties to Functions at the Cellular and Tissue Level |
Regulation of Aquaporin Expression and Water Transport Activity |
Microbial Water Channels and Glycerol Facilitators / Gerald Kayingo ; Roslyn M. Bill ; Guiseppe Calamita ; Stefan Hohmann ; Bernard A. PriorChapter 8: |
Microbial Aquaporins and Glycerol Facilitators |
Transport Properties and Channel Selectivity of Microbial MIP Channels |
From Primary to Quaternary Structure in Microbial MIPs |
Physiological Roles |
Microbial MIP Channels in Osmoregulation |
Control of the Function of Microbial MIP Channels |
Conclusions and Future Perspectives |
Future Directions of Aquaporin Research / Chapter 9: |
Identification and Characterization of New MIP Channels |
Why Have So Many MIP Channels? |
Analysis of the Physiological Roles of Aquaporins |
Structure and Function |
Aquaporins as Targets for Treatment of Human Disease |
Aquaporins as Possible Targets for Genetic Engineering and Crop Improvement |
Metabolic Engineering with Aquaporins |
The Aquaporin Research Community |
Index |
Contributors |
Preface |
Previous Volumes in Series |
Discovery of the Aquaporins and Their Impact on Basic and Clinical Physiology / Peter Agre ; Mario J. Borgnia ; Masato Yasui ; John D. Neely ; Jennifer Carbrey ; David Kozono ; Eric Beitz ; Jason Hoffer ; Virginia Leitch ; Landon S. KingChapter 1: |
Pre-Aquaporin Era / I.: |
The First Recognized Water Channel Protein / II.: |