Cyclodextrin Complexes of Lanthanide Ions for Homogeneous Hydrolysis of Amides
Relevance of the Lanthanide-Mediated Amide Hydrolysis to DNA Hydrolysis
Conclusion
Acknowledgment
Abbreviations
Co(III)-Promoted Hydrolysis of Amides and Small Peptides / David A. Buckingham ; Charles R. ClarkChapter 3:
Early Studies and Scope
Co(III) Linkage Isomers and Isomerization
Hydrolysis by Direct Polarization
Bimolecular Reactions of Co-OH[subscript 2]/OH
Intramolecular Reactions of CoOH[subscript 2]/OH
Kinetic Parameters and Reaction Mechanism
Related Nonmetal Hydrolysis Reactions / 8.:
Synthetic Cu(II) and Ni(II) Peptidases / Gregory M. Polzin ; Judith N. BurstynChapter 4:
Hydrolysis of Simple Peptides by Cu(II) and Ni(II) Ions in Solution
Cleavage of Substrates Containing a Metal Binding Site by Cu(II) and Ni(II) Ions
Cleavage of Amides, Peptides, and Proteins by Defined Metal Complexes
Conclusions
Palladium(II) and Platinum(II) Complexes as Synthetic Peptidases / Nebojsa M. Milovic ; Nenad M. KosticChapter 5:
Selective Binding of Metal Complexes to Peptides and Peptide Cleavage
Cleavage of Proteins
Prospects
Acknowledgments
Abbreviations and Symbols
Protease Activity of 1,10-Phenanthroline-Copper Systems / Makoto Kito ; Reiko UradeChapter 6:
Can Free Copper(II) Ions Degrade Proteins?
Protein Degradation by the 1,10-Phenanthroline-Copper(II) Complex
Protease Activity of the Chemically Modified 1,10-Phenanthroline-Copper(II) Complex
Specific Protein Degradation by Copper(II) Ions / Geoffrey AllenChapter 7:
Peptide Sequence Specificity for Cleavage by Copper(II) Ions
Conditions Affecting the Rate of Cleavage of Peptides by Copper(II) Ions
Possible Mechanisms of Copper(II)-Mediated Hydrolysis of Peptide Bonds
Physiological Relevance of the Degradation of Proteins by Copper(II) Ions
Artificial Iron-Dependent Proteases / Saul A. Datwyler ; Claude F. MearesChapter 8:
Introduction: Historical Background and Concepts
Principles and Practical Aspects
Methodology
Transcription Complexes in Escherichia coli
Hydroxyl Radical Footprinting of Proteins Using Metal Ion Complexes / Tomasz Heyduk ; Noel Baichoo ; Ewa HeydukChapter 9:
Experimental Methodology of Protein Footprinting
Applications of Protein Footprinting Methodology
Future Directions
Abbreviations and Definitions
Nickel- and Cobalt-Dependent Oxidation and Cross-Linking of Proteins / Steven E. Rokita ; Cynthia J. BurrowsChapter 10:
Determinants of Nickel- and Cobalt-Dependent Oxidation
Intrinsic Sensitivity of Native Proteins
Mapping Tertiary and Quaternary Structure of Proteins
Effects of Metal Ions on the Oxidation and Nitrosation of Cysteine Residues in Proteins and Enzymes / Ann M. English ; Dean E. WilcoxChapter 11:
Background: Properties and Biological Roles of Cysteine Residues
Oxidation of Cysteines
Nitrosation of Cysteines
Protein Cross-Linking Mediated by Metal Ion Complexes / Kathlynn C. Brown ; Thomas KodadekChapter 12:
Small-Molecule Cross-Linking Reagents Used Free in Solution
Development of Affinity Cross-Linking Reagents: Use of Peptides or Proteins to Deliver a Cross-Linking Reagent Site-Specifically
Ferrocenoyl Amino Acids and Peptides: Probing Peptide Structure / Heinz-Bernhard Kraatz ; Marek GalkaChapter 13:
Introduction: Organometallic Probes in Biological Systems
Synthetic Studies of Ferrocenoyl Amino Acids and Peptides
Structural and Theoretical Studies
Electrochemistry of Ferrocenoyl Amino Acids and Peptides
Summary
Synthetic Analogs of Zinc Enzymes / Gerard ParkinChapter 14:
Structural and Functional Models of Zinc Enzymes as Classified by Active Site Composition
Use of Metal Ion Substitution to Provide Insight into the Structures and Mechanisms of Action of Zinc Enzymes
Perspectives
Mimicking Biological Electron Transfer and Oxygen Activation Involving Iron and Copper Proteins: A Bio(in)organic Supramolecular Approach / Martinus C. FeitersChapter 15:
Mimics for Iron-Sulfur Proteins
Mimics for Blue Copper Proteins
Cytochrome P450 Mimics
Mimics for Oxygen Binding and Activation by Copper Proteins
Activator Proteins for Lysosomal Glycolipid Hydrolases / E. Conzelmann ; K. Sandhoff
Isolation and Analysis of Cell Walls from Plant Material / R. R. Selvendran ; M. A Neill
Electro-Optical Reflection Methods for Studying Bioactive Substances at Electrode-Solution Interfaces-An Approach to Biosurface Behavior / K. Takamura ; F. Kusu
Isoelectric Focusing in Immobilized pH Gradients: Theory and Newer Technology / P. G. Righetti ; E. Gianazza
Assays for Superoxide Dismutase / J. V. Bannister ; L. Calabrese
The Radiation Inactivation Method as a Tool to Study Structure-Function Relationships in Proteins / G. Beauregard ; A. Maret ; R. Salvayre ; M. Potier
Immunoassay with Electrochemical Detection / W. R. Heineman et al.
Index
Activator Proteins for Lysosomal Glycolipid Hydrolases / E. Conzelmann ; K. Sandhoff
Isolation and Analysis of Cell Walls from Plant Material / R. R. Selvendran ; M. A Neill
Electro-Optical Reflection Methods for Studying Bioactive Substances at Electrode-Solution Interfaces-An Approach to Biosurface Behavior / K. Takamura ; F. Kusu
Nick Cozzarelli: A personal remembrance / Stephen D. Levene ; Lynn Zechiedrich
Mathematical methods in DNA topology: Applications to chromosome organization and site-specific recombination / Javier Arsuaga ; Yuanan Diao ; Mariel Vazquez
Conformational statistics of DNA and diffusion equations on the Euclidean group / Gregory S. Chirikjian
Perspectives on DNA looping / Laura Finzi
Differences between positively and negatively supercoiled DNA that topoisomerases may distinguish / Jonathan M. Fogg ; Daniel J. Catanese, Jr. ; Graham L. Randall ; Michelle C. Swick
Calibration of tethered particle motion experiments / Lin Han ; Bertrand H. Lui ; Seth Blumberg ; John F. Beausang ; Philip C. Nelson ; Rob Phillips
Useful intrusions of DNA topology into experiments on protein-DNA geometry / Jason D. Kahn ; James R. Jenssen ; Vasavi Vittal
Topological analysis of DNA-protein complexes / Soojeong Kim ; Isabel K. Darcy
Closing the loop on protein-DNA interactions: Interplay between shape and flexibility in nucleoprotein assemblies having implications for biological regulation / Yongli Zhang
Four-way helical junctions in DNA molecules / David M.J. Lilley
Micromechanics of single supercoiled DNA molecules / John F. Marko
Flexibility of nucleosomes on topologically constrained DNA / Andrei Sivolob ; Christophe Lavelle ; Ariel Prunell
The mathematics of DNA structure, mechanics, and dynamics / David Swigon
Paradox regained: a topological coupling of nucleosomal DNA wrapping and chromatin fibre coiling / Andrew Travers
Statistical-mechanical analysis of enzymatic topological transformations in DNA molecules / Alexander Vologodskii
List of workshop participants
Foreword
Preface
Nick Cozzarelli: A personal remembrance / Stephen D. Levene ; Lynn Zechiedrich
organized by the Science Council of Japan ; under the auspices of the International Union Biochemistry ; secretariat Seventh International Congress of Biochemistry
出版情報:
Tokyo : The Science Council of Japan, 1967 v. ; 28 cm