1.
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Jeremy McPeak, Paul Wilton
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Indianapolis, IN : Wrox, c2015 xxiii, 742 p. ; 24 cm
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2.
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Haruki Murakami ; translated from the Japanese by Ted Goossen
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New York : Vintage Books, 2015 xvii, 101, 131 p. ; 21 cm
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Vintage international
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目次情報:
Hear the wind sing : a novel
Pinball, 1973 : a novel
Hear the wind sing : a novel
Pinball, 1973 : a novel
3.
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David Ebershoff
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New York : Penguin Books, 2015 270, 15 p. ; 21 cm
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Penguin books
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written by Lee Davis
5.
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written by Anita Ganeri
6.
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edited by Dietmar Hutmacher, Wojciech Chrzanowski
7.
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edited by Svetlana Boriskina, Nikolay I. Zheludev
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Singapore : Pan Stanford Pub., c2015 xix, 515 p. ; 24 cm
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written and researched by Sarina Singh ... [et al.]
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Footscray, Vic. : Lonely Planet, 2015 1245 p. ; 20 cm
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Fiona Cobb
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Boca Raton, FL : CRC Press, c2015 xix, 445 p. ; 21 cm
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10.
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edited by Peter Grunwald
11.
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Michael J. Moran ... [et al.]
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Hoboken, N.J. : Wiley, c2015 xviii, 867 p. ; 28 cm
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by Anne-Marie O'Connor
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New York : Vintage Books, 2015 xviii, 349 p. ; 21 cm
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M.J. Arlidge
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New York : New American Library, 2015 420 p. ; 21 cm
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Ian McEwan
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New York : Anchor Books, 2015 221 p ; 21 cm
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Lori Nelson Spielman
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New York : Plume, 2015 355 p. ; 21 cm
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Claudia Thesenfitz
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Berlin : Ullstein, 2015 268 p. ; 19 cm
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Paula Hawkins
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London : Transworld, 2015 316 p. ; 24 cm
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Miodrag Kojadinovic
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Hong Kong : Earnshaw Books, c2015 115 p. ; 18 cm
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Margaret Atwood
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London : Virago, 2015 311 p. ; 20 cm
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Stephen King
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London : Hodder & Stoughton, 2015, c2014 390 p. ; 18 cm
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Michael Punke
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London : The Borough Press, 2015 308 p. ; 20 cm
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Nathaniel Philbrick
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London : William Collins, 2015 302 p. ; 20 cm
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Bryan Reardon
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New York, NY : William Morrow, an imprint of HarperCollinsPublishers, c2015 264, 13 p. ; 20 cm
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Emma Donoghue
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New York, NY : Little, Brown and Company, 2015 361 p. ; 17 cm
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Alex Bellos, Edmund Harriss
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Edinburgh : Canongate, 2015 1 volume ; 22 cm
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26.
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by Raquel Pelzel ; photographs by Evan Sung
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London : Phaidon, [2015] 119 pages ; 25 cm
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A.G. Riddle
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London : Head of Zeus, 2015 537 p. ; 20 cm
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The Atlantis trilogy ;
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28.
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Clifton Collins, Jr. and Gustavo "Goose" Alvarez ; with an foreword by Samuel L. Jackson
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New York : Workman Publishing, [2015] xxi, 153 pages ; 18 cm
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29.
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N.K. Jemisin
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New York, NY : Orbit, 2015 498 p. ; 21 cm
シリーズ名:
The broken earth ; 1
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30.
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Maria V. Snyder
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Richmond : Mira Ink, 2015 409 p.
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A chronicles of Ixia novel ;
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31.
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Michael Booth
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London : Vintage Books, 2015 406 p. ; 20 cm
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32.
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Ella Frances Sanders
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London : Square Peg, 2015 1 v. ; 18 × 20 cm
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33.
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David Freeling and Vince Kotchian
34.
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written and researched by Brendan Sainsbury, Luke Waterson
出版情報:
Footscray, Vic. : Lonely Planet, 2015 543 p. ; 20 cm
シリーズ名:
Lonely Planet
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35.
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Jonathan Pevsner
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Chichester : Wiley Blackwell, 2015 xxxiii, 1124 p. ; 29 cm
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36.
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Anne Morrow Lindbergh
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London : Chatto & Windus, [2015] 156 p. ; 18 cm
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37.
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editor, Donglu Shi
38.
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Hongbin Ma
出版情報:
New York : Springer, c2015 xvi, 427 p.
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39.
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Katherine Blundell
40.
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Mike Goldsmith
41.
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editors, Laura Crawford, Elin Berglund, Branislava Vladisavljevic ; language writers, Yoshi Abe, Keiko Hagiwara
目次情報:
続きを見る
About Japanese: Learn about Japanese , build your own sentences and pronounce words correctly
Introduction
Top Phrases
Pronunciation
Grammar
Travel Phrases: Ready-made phrases for every situation û buy a ticket, book a hotel and much more
Basics
Understanding
Numbers & Amounts
Time & Dates
Practical
Transport
Border Crossing
Directions
Accommodation
Shopping
Communications
Money & Banking
Business
Sightseeing
Senior & Disabled Travellers
Travel with Children
Social
Meeting People
Interests
Feelings & Opinions
Going Out
Romance
Beliefs & Culture
Sports
Outdoors
Safe Travel
Emergencies
Police
Health
Food
Eating Out
Self-Catering
Vegetarian & Special Meals
Menu Decoder: Dishes and ingredients explained û order with confi dence and try new foods
Two-Way Dictionary: Quick reference vocabulary guide û 3500 words to help you communicate
EnglishûJapanese Dictionary
JapaneseûEnglish Dictionary
Index
About Japanese: Learn about Japanese , build your own sentences and pronounce words correctly
Introduction
Top Phrases
42.
図書
written and researched by Rebecca Milner, Simon Richmond
出版情報:
Footscray, Vic. : Lonely Planet, 2015 295 p. ; 20 cm.
シリーズ名:
Lonely Planet
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43.
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Chris Rowthorn
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Hawthorn, Vic. : Lonely Planet, 2015 223 p. ; 20 cm.
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Lonely Planet
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44.
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Milad Radiom
45.
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Philip Moriarty, Sebastién Gauthier, editors
46.
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新渡戸稲造著
出版情報:
東京 : IBCパブリッシング, 2015 210 p. ; 21 cm
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47.
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Cutnell & Johnson
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Hoboken, N.J. : John Wiley & Sons, 2015 xvi, 836, 22, 16 p. ; 28 cm
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48.
図書
Damian Harper ... [et al.]
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Footscray, Vic. : Lonely Planet, 2015 1053 p. ; 20 cm
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Lonely Planet
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49.
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Nicola Williams ... [et al.]
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Footscray, Vic. : Lonely Planet, 2015 1014 p. ; 20 cm
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Lonely Planet
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50.
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Charles Rawlings-Way ... [et al.]
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Footscray, Vic. : Lonely Planet, 2015 1109 p. ; 20 cm
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Lonely Planet
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51.
図書
Neil Wilson ... [et al.]
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Footscray, Vic. : Lonely Planet, 2015 1054 p. ; 20 cm
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Lonely Planet
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52.
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[language writer, Yoshi Abe, Keiko Hagiwara]
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[Footscray, Vic.] : Lonely Planet, 2015 271 p. ; 14 cm., in box 15 × 15 × 3 cm.
シリーズ名:
Lonely Planet phrasebooks
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53.
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edited by Marcelo E. Tolmasky, Juan C. Alonso
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Washington, D.C. : ASM Press, c2015 xxi, 697 p. ; 29 cm
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54.
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Marlon James
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London : Oneworld, 2015 xiv, 688 p. ; 20 cm
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56.
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A.A. Markin and M.Yu. Sokolova
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Cambridge : Cambridge International Science Publishing, 2015 viii, 325 p. ; 24 cm
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57.
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edited by Dipanjan Pan
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Boca Raton, Fla. : CRC, c2015 xiii, 169 p., [20] p. of plates ; 24 cm
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58.
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Kanzo Uchimura
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東京 : IBCパブリッシング, 2015 238 p. ; 21 cm
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59.
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prepared under the direction of the ASM International Handbook Committee ; volume editor, Kenneth B. Tator
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Material Park, Ohio : ASM International, c2015 xiii, 545 p. ; 29 cm
シリーズ名:
ASM handbook ; v. 5B
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60.
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Richard Flanagan
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London : Vintage Books, 2015 448 p. ; 18 cm
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61.
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グリム兄弟著
62.
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Neil Wilson, Andy Symington
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Footscray : Lonely Planet, 2015 495 p. ; 20 cm
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Lonely Planet
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63.
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Anja Mutić, Peter Dragicevich
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Footscray : Lonely Planet, 2015 351 p. ; 20 cm
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Lonely Planet
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64.
図書
Neil Wilson... [et al.]
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Footscray : Lonely Planet, 2015 718 p. ; 20 cm
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Lonely Planet
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65.
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edited by Lawrence Berliner
66.
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edited by Neale D. Ridgway and Roger S. McLeod
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Amsterdam : Elsevier, 2015, c2016 xxi, 599 p. ; 24 cm
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67.
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Alison Thomas
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New York : Garland Science, c2015 viii, 262 p. ; 25 cm
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68.
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prepared under the direction of the ASM International Handbook Committee ; volume editors, Prasan K. Samal, Joseph W. Newkirk
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Materials Park, Ohio : ASM International, c2015 xiv, 907 p. ; 29 cm
シリーズ名:
ASM handbook ; v. 7
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69.
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Roger Toogood, Ph.D.
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Mission, KS : SDC Publications, c2015 1 v. (various pagins) ; 28 cm
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70.
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Vladimir I. Bakhmutov
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Boca Raton : CRC Press, c2015 xv, 344 p. ; 24 cm
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71.
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Drahomír Hnyk, Michael L. McKee, editors
72.
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Patricia Highsmith
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New York : W.W. Norton, 2015, c1993 292 p. ; 21 cm
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73.
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Kazuo Ishiguro
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London : Faber & Faber, 2015 362 p. ; 18 cm
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戴暁旬著
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東京 : アスク, 2015.4- 冊 ; 21cm
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75.
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C. S. Jog
76.
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H. Stephen Stoker
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Boston, Mass. : Cengage Learning, 2015, c2016 xvi, 983, 24, 32 ; 29 cm
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77.
図書
editor, Eric E. Bouhassira ; associate editor, Krishna S. Vyas
出版情報:
Los Angeles : SAGE Reference, c2015 3 v. (xli, 1471 p.) ; 29 cm
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78.
図書
Andreas Manz ... [et al.]
出版情報:
London : Imperial College Press, c2015 xx, 236 p. ; 24 cm
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79.
図書
Nisioisin ; art by Vofan ; translated by Ko Ransom
出版情報:
New York : Vertical, 2015 344 p. ; 19 cm
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80.
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Timothy C. Parker and Seth R. Marder
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Cambridge : Royal Society of Chemistry, c2015 xii, 284 p. ; 24 cm
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81.
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82.
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Celeste Ng
83.
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Constance Hammond
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Amsterdam : Elsevier/Academic Press, c2015 ix, 433 p. ; 29 cm
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84.
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Tim J. Stevens, Wayne Boucher
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Cambridge : Cambridge University Press, 2015 viii, 702 p. ; 25 cm
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85.
図書
John L. Tymoczko, Jeremy M. Berg, Lubert Stryer
出版情報:
New York : W.H. Freeman, c2015 xxvii, 761, A15, B16, C42, D31 p. ; 28 cm
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86.
図書
Thomas M. Lillesand, Ralph W. Kiefer, Jonathan W. Chipman
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Hoboken, N.J. : Wiley, c2015 xii, 720 p., [36] p. of plates ; 24 cm
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87.
図書
Marco Schwartz, Oliver Manickum
88.
図書
[edited by] Nalan Kabay, Marek Bryjak, Nidal Hilal
出版情報:
Amsterdam : Elsevier, c2015 xiii, 390 p. ; 25 cm
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89.
図書
edited by Ben M. Dunn
出版情報:
Hoboken, N.J. : Wiley, c2015 xvi, 318 p., [8] p. of colored plates ; 25 cm
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目次情報:
続きを見る
Preface
List of Contributors
Peptide Therapeutics / Nader Fotouhi1:
History of Peptides as Drugs / 1.1:
Factors Limiting the Use of Peptides in the Clinic / 1.2:
Advances that have Stimulated the Use of Peptides as Drugs / 1.3:
Development of Peptide Libraries / 1.4:
Modification of Peptides to Promote Stability and Cell Entry / 1.5:
Targeting Peptides to Specific Cells / 1.6:
Formulations to Improve Peoperties / 1.7:
References
Methods for the Peptide Synthesis and Analysis / Judit Tulla-Puche ; Ayman El-Faham ; Athanassios S. Galanis ; Eliandre de Oliveira ; Aikaterini A. Zompra ; Fernando Albericio2:
Introduction / 2.1:
Solid Supports / 2.2:
Linkers / 2.3:
Protecting Groups / 2.4:
The Special Case of Cysteine / 2.4.1:
Methods for Peptide Bond Formation / 2.5:
Peptide-Bond Formation from Carbodiimide-Mediated Reactions / 2.5.1:
Peptide-Bond Formation from Preformed Symmetric Anhydrides / 2.5.2:
Peptide-Bond Formation from Acid Halides / 2.5.3:
Peptide-Bond Formatiion from Phosphonium Salt-Mediated Reactions / 2.5.4:
Peptide-Bond Formation from Aminium/Uronium Salt-Mediated Reactions / 2.5.5:
Solid-Phase Stepwise Synthesis / 2.6:
Long Peptides / 2.6.1:
Synthesis in Solution / 2.7:
Nα Protection of the N-Terminal Amino Acid Derivative or Fragment / 2.7.1:
Carboxy-Group Protection of the C-terminal Amino-Acid Derivative or Fragment / 2.7.2:
Peptide Bond Formation / 2.7.3:
Hybrid Synthesis-Combination of Solid and Solution Synthesis / 2.8:
Classical Segment Condensation / 2.8.1:
Native Chemical Ligation / 2.8.2:
Cyclic Peptides / 2.9:
Depsipeptides / 2.10:
Separation and Purification of Peptides / 2.11:
Gel-Filtration Chromatography / 2.11.1:
Ion-Exchange Chromatography / 2.11.2:
Reverse-Phase High Performance Liquid Chromatography / 2.11.3:
Characterization of Peptides Through Mass Spectrometry / 2.12:
Ionization Source / 2.12.1:
Mass Analysers / 2.12.2:
Peptide Fragmentation / 2.12.3:
Quantification by MS / 2.12.4:
Conclusions / 2.13:
Acknowledgments
Abbreviations
Peptide Design Strategies for G-Protein Coupled Receptors (GPCRs) / Anamika Singh ; Carrie Haskell-Luevano3:
Classification of GPCRs / 3.1:
Catalog of Peptide-Activated G-Protein Coupled Receptors / 3.3:
Structure of GPCRs: Common Features / 3.4:
Crystal Structures / 3.4.1:
GPCR Activation / 3.5:
Ligand (Peptide) Binding and Receptor Activation / 3.5.1:
Common Structural Changes among GPCRs / 3.5.2:
G-Protein Coupled Intracellular Signaling Pathwayws / 3.5.3:
Structure and Function of Peptide Hormones / 3.6:
Design Approaches for GPCR Selective Peptide Ligands / 3.7:
Structure-Activity Relationship (SAR) Studies / 3.7.1:
Chimeric Peptide Analogs / 3.7.2:
Combinatorial Libraries / 3.7.3:
Three-Dimensional (3D) GPCR Homology Molecular Modeling / 3.7.4:
Peptide-Resed Inhibitors of Enzymes / Anna Knapinska ; Sabrina Amar ; Trista K. Robichaud ; Gregg B. Fields3.8:
Angiotensin-Converting Enzyme and Neprilysin/Neutral Endopeptidase / 4.1:
Peptide Inhibitors of the HIV-1 Viral Life Cycle / 4.3:
Matrix Metalloproteinases / 4.4:
Antrax Lethal Factor Inhibition by Defensins / 4.5:
Kinases / 4.6:
Glycosyltransferases (Oligosaccharyltransferases) / 4.7:
Telomerase Inhibitors / 4.8:
Tyrosinase / 4.9:
Peptidyl-Prolyl Isomerase / 4.10:
Histone Modifying Enzymes / 4.11:
Histone Deacetylase / 4.11.1:
Histone Methyl-Transferase / 4.11.2:
Putting it all Together: Peptide Inhibitor Applications in Skin Care / 4.12:
Strategies for the Discovery of Novel Peptide Inhibitors / 4.13:
Discovery of Peptide Drugs as Enzyme Inhibitors and Activators / Jeffrey-Tri Nguyen ; Yoshiaki Kiso5:
Peptide Residue Nomenclature / 5.1:
Common Methods of Drug Design / 5.1.2:
Phases of Drug Development / 5.1.3:
Enzyme Types That Process Peptides / 5.2:
Enzymes as Chemicals in Consumer and Medical Products / 5.2.1:
Nonspecific Enzyme Inhibitors / 5.2.2:
Amino Acid Drugs / 5.3:
Thyroid Hormones / 5.3.1:
An Ornithine Decarboxylase Inhibitor / 5.3.2:
Catecholamines / 5.3.3:
Serine Proteases and Blood Clotting / 5.4:
Blood Coagulating Agents / 5.4.1:
Enzymes as Blood Anticoagulants / 5.4.2:
Direct Thrombin Inhibitors as Blood Anticoagulants / 5.4.3:
Diabetes Mellitus / 5.5:
Peptide Hormones and Blood Glucose Regulation / 5.5.1:
Glucagon-Like Peptide-1 and Analogs / 5.5.2:
Dipeptidyl Peptidase-4 Inhibitors / 5.5.3:
Renin-Angiotensin-Aldosterone System / 5.6:
ACE Inhibitors / 5.6.1:
Renin Inhibitors / 5.6.2:
Penicillin and Cephalosporin Antibiotics / 5.7:
HIV Protease / 5.8:
HIV-Specific Protease Inhibitors / 5.8.1:
Peptide Drugs Under Development / 5.9:
Cathepsins / 5.9.1:
Cysterine Proteases / 5.9.2:
Secretases in Alzheimer's Disease / 5.9.3:
Trypsin-Like Serine Proteases / 5.9.4:
Zinc Metalloproteases / 5.9.5:
Non-Mammalian Proteases / 5.9.6:
Discussion / 5.10:
Discovery of Peptide Drugs from Natural Sources / Sónia T Henriques ; David J Craik6:
Peptides are Involved in the Host Defense Mechanism of Living Organisms / 6.1:
Cationic AMPs from Eukaryotes, Peptides that Target the Membrane / 6.2.1:
Peptides and the Host Defense in Bacteria-Bacteriocins / 6.2.2:
Cyclotides, Ultra-Stable Peptides that are Part of Plant Defense Mechanism / 6.2.3:
Animal Venoms, a Rich Source of Peptides with Therapeutic Potential / 6.3:
Conotoxins, a Naturally Occurring Combinatorial Peptide Library / 6.3.1:
Optimization of Peptides for Drug Development / 6.4:
Chemical Modifications to Improve Activity / 6.4.1:
Modification of Peptides of Limit Metabolism / Isuru R. kumarasinghe ; Victor J. Hruby6.5:
Introduction of Unnatural Amino Acids / 7.1:
Cyclization of Linear Peptides to Improve Stability Toward Blood and Brain Protease Degradation / 7.3:
Introduction of D-Amino Acids into Peptides Improves Stability Toward Blood and Brain Protease Degradation / 7.4:
Introduction of β-Amino Acids Increases the Stability Toward Blood and Brain Protease Degradation / 7.5:
INtroduction of Peptide Bond Isosteres / 7.6:
Introduction of a N-Methylation of the Amide Bond of Peptides can Improve the Stability Toward Blood and Brain Protease Degradation / 7.7:
Use of Unnatural Amino Acids-Use of Topographically Constrained Amino Acid / 7.8:
Using Glycosylated Amino Acids to Increase the Resistance of the Proteolytic Degradation / 7.9:
Creation of Peptides as Multiple Antigen Peptide (MAP) Dendrimeric Forms Increases the Stability Toward Blood and Brain Protease Degradation / 7.10:
Halogenations of Aromatic Residues in Peptides can Reduce the Enzymatic Recognition Required for Peptide Hydrolysis / 7.11:
Concluding Discussion / 7.12:
Delivery of Peptide Drugs / 8:
Lipinski's Rule of Five / 8.1:
Molecular Size / 8.2.1:
Lipophilicity / 8.2.2:
Chemical Stability / 8.2.3:
Routes of Administration / 8.2.4:
Approaches to Delivering Peptide Drugs / 8.3:
Enzyme Inhibitors / 8.3.1:
Permeation Enhancers / 8.3.2:
Delivery of Peptide Drugs across the Blood-Brain Barrier / 8.3.3:
Parenteral Peptide Drugs / 8.4:
Topical Peptide Drugs for Local Effects / 8.5:
Cosmeceutical Peptides / 8.5.1:
Intranasal Peptide Drug Delivery / 8.6:
Enteral Peptide Drugs / 8.7:
DIfferent Routes of Administration for Insulin / 8.8:
Index / 8.9:
Preface
List of Contributors
Peptide Therapeutics / Nader Fotouhi1:
90.
図書
Gérald Tenenbaum ; translated by Patrick D.F. Ion
91.
図書
Donald L. Pavia ... [et al.]
出版情報:
Stamford : Cengage Learning, c2015, 2009 xvii, 690, 17, 45, 12 p. ; 26 cm
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92.
図書
Douglas Stamps
出版情報:
Mission, KS : SDC Publications, c2015 viii, 307 p. ; 28 cm
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93.
図書
John Finney
94.
図書
edited by Bob B. Buchanan, Wilhelm Gruissem, and Russell L. Jones
出版情報:
Chichester, West Sussex : John Wiley & Sons, 2015 xv, 1264 p. ; 28 cm
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95.
図書
edited by Seth Love ... [et al.]
出版情報:
Boca Raton : CRC Press, c2015 2 v. ; 29 cm
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96.
図書
Tenshin Okakura
出版情報:
東京 : IBCパブリッシング, 2015 167 p. ; 21cm
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97.
図書
Kye-Si Kwon and Steven Ready
出版情報:
Weinheim : Wiley-VCH, c2015 xii, 278 p. ; 25 cm
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98.
図書
Leiva Casemiro Oliveira, ... [et al.]
99.
図書
Diethelm Johannsmann
100.
図書
Kanji Text Research Group, University of Tokyo
出版情報:
Tokyo : Tuttle Publishing, 2015- 2 v. ; 26 cm
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