Preface to the Series |
Preface to Volume 19 |
Contributors |
Contents of Other Volumes |
The Discovery of Ionophores: An Historical Account / Berton C. PressmanChapter 1: |
Abbreviations |
References |
Tetracyclines and Daunorubicin / R. Bruce MartinChapter 2: |
Introduction / 1.: |
Tetracyclines / 2.: |
Daunorubicin / 3.: |
Interaction of Metal Ions with Streptonigrin and Biological Properties of the Complexes / Joseph HajduChapter 3: |
Structural and Chemical Properties of Streptonigrin and Its Metal Complexes |
Biological Activity and Suggested Mechanistic Schemes for the Antitumor Action of Streptonigrin |
Conclusions / 4.: |
Bleomycin Antibiotics: Metal Complexes and Their Biological Action / Yukio Sugiura ; Tomohisa Takita ; Hamao UmezawaChapter 4: |
Structural and Synthetic Aspects of Bleomycin |
Characteristics of Bleomycin-Metal Complexes |
Oxygen Activation and Redox Cycle of the Bleomycin-Iron Complex |
Interaction of Bleomycin and Its Iron Complex with DNA / 5.: |
Sequence-Specific DNA Cleavage by the Bleomycin-Iron Complex / 6.: |
Metal Complexes and DNA Cleavage of Bleomycin Analogs: Peplomycin, Tallysomycin, and Phleomycin / 7.: |
Metal Complexes and Oxygen Activation by Synthetic Analogs and Biosynthetic Intermediates of Bleomycin / 8.: |
Molecular Mechanism of Bleomycin Action / 9.: |
Interaction Between Valinomycin and Metal Ions / K. R. K. Easwaran10.: |
Structure and Conformation of Free Valinomycin |
Structure and Conformation of Valinomycin-Metal Ion Complexes |
Valinomycin-Metal Ion Complexes in Transmembrane Ion Transport |
Abbreviations and Definitions |
Beauvericin and the Other Enniatins / Larry K. SteinraufChapter 6: |
Ion Binding |
Membrane Transport |
Analogs |
Complexing Properties of Gramicidins / James F. Hinton ; Roger E. Koeppe IIChapter 7: |
Structural Properties |
Ion-Complexing Properties |
Transport Properties |
Nactins: Their Complexes and Biological Properties / Yoshiharu Nawata ; Kunio Ando ; Yoichi IitakaChapter 8: |
Molecular Structure of Nactins |
Complexes |
Biological Properties |
Cation Complexes of the Monovalent and Polyvalent Carboxylic Ionophores: Lasalocid (X-537A), Monensin, A23187 (Calcimycin), and Related Antibiotics / George R. PainterChapter 9: |
Structure of Ionophore-Cation Inclusion Complexes |
Techniques for Measuring Equilibrium Ionophore-Ion Affinities |
Carboxylic Ionophore-Mediated Ion Transport |
Biological Test Systems |
Conformational Aspects of Ion Capture and Membrane Transport |
Biological Applications of Ionophores |
Overview |
Complexes of D-Cycloserine and Related Amino Acids with Antibiotic Properties / Paul O'BrienChapter 10: |
Mode of Action |
Uses of D-Cycloserine |
Organic Chemistry of D-Cycloserine |
Metal Ion Coordination by D-Cycloserine |
Metal Ion Coordination by D-Cycloserine Derivatives |
Iron-Containing Antibiotics / J. B. Neilands ; J. R. ValentaChapter 11: |
Iron(III) Complexes |
Iron(II) Complexes |
Miscellaneous Compounds |
General Conclusions |
Cation-Ionophore Interactions: Quantification of the Factors Underlying Selective Complexation by Means of Theoretical Computations / Nohad Gresh ; Alberte PullmanChapter 12: |
Outline of the Methodology |
Selective Binding of Alkali Cations by Valinomycin |
Selective Complexation of K[superscript +], Na[superscript +], and NH[superscript + subscript 4] by Nonactin |
Selective Binding of Mg[superscript 2+] and Ca[superscript 2+] by Ionophore A23187 |
Structural Properties of Valinomycin and A23187 |
Energy Profiles for Single and Double Occupancy by Na[superscript +] of the Gramicidin A Channel |
Author Index |
Subject Index |