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1.

図書

図書
Sigel, Helmut
出版情報: New York : Marcel Dekker, c1987  xxv, 295 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 21
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Preface to the Series
Preface to Volume 21
Contributors
Contents of Other Volumes
Nuclear Relaxation Times as a Source of Structural Information / Gil Navon ; Gianni ValensinChapter 1:
Theoretical Considerations / 1.:
Applications / 2.:
Abbreviations
References
Nuclear Relaxation in NMR of Paramagnetic Systems / Ivano Bertini ; Claudio Luchinat ; Luigi MessoriChapter 2:
Nuclear Relaxation and Observability of the NMR Signals
Physical Consequences of Unpaired Electron-Nucleus Coupling
T[superscript -1 subscript 1M] and Nuclear Magnetic Relaxation Dispersion (NMRD) / 3.:
T[superscript -1 subscript 2M] / 4.:
Electron Relaxation Mechanisms / 5.:
Electron and Nuclear Relaxation in Magnetically Coupled Systems / 6.:
Concluding Remarks / 7.:
NMR Studies of Magnetically Coupled Metalloproteins / Lawrence Que, Jr. ; Michael J. MaroneyChapter 3:
Introduction
Physical Background
Superoxide Dismutase
Hemerythrin
Ribonucleotide Reductase
Uteroferrin
Ferredoxins
Summary / 8.:
Proton NMR Studies of Biological Problems Involving Paramagnetic Heme Proteins / James D. SatterleeChapter 4:
Heme Proteins
The Hyperfine Shift in Paramagnetic Heme Proteins
Resonances of the Porphyrin Ring
Resonances of Axial Ligands
Resonances of the Heme Pocket not Attributable to Heme Ligands
Proton NMR Studies of Protein-Protein Complexes
Conclusion
Metal-Porphyrin Induced NMR Dipolar Shifts and Their Use in Conformational Analysis / Nigel J. Clayden ; Geoffrey R. Moore ; Glyn WilliamsChapter 5:
Theory
Structural and Magnetic Properties of Metalloporphyrins
Conformational Analysis
Conclusions and Outlook
Relaxometry of Paramagnetic Ions in Tissue / Seymour H. Koenig ; Rodney D. Brown IIIChapter 6:
General Background
Relaxometry of Fe[superscript 3+]
Relaxometry of Mn[superscript 2+]
Relaxometry of Gd[superscript 3+]
The Present and Future
Author Index
Subject Index
Preface to the Series
Preface to Volume 21
Contributors
2.

図書

図書
Sigel, Helmut
出版情報: New York : Marcel Dekker, c1987  xxiii, 290 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 22
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3.

図書

図書
edited by Helmut Sigel with Astrid Sigel
出版情報: New York : M. Dekker, c1988  xxix, 488 p. ; 23 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 23
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Preface to the Series
Preface to Volume 23
Contributors
Contents of Other Volumes
Handbook on Toxicity of Inorganic Compounds
Nickel in the Natural Environment / Robert W. Boyle ; Heather A. RobinsonChapter 1:
General Chemistry and Geochemistry of Nickel / 1.:
Nickel in the Lithosphere and in Nickel Deposits / 2.:
Nickel in the Pedosphere / 3.:
Nickel in the Hydrosphere / 4.:
Nickel in the Atmosphere / 5.:
Nickel in the Biosphere and Its Degradation Products / 6.:
General Summary / 7.:
References
Nickel in Aquatic Systems / Pamela StokesChapter 2:
Introduction
Nickel as an Essential Element for Aquatic Biota
Nickel Toxicity
Partitioning and Chemical Forms of Nickel in Water
Bioaccumulation of Nickel by Aquatic Biota
Food Chain Transfer of Nickel
Conclusions and Recommendations
Nickel and Plants / Margaret E. Farago ; Monica M. ColeChapter 3:
Nickel--An Essential Element for Plants?
Nickel Uptake and Nickel Content of Plants: Background Levels
Nickel Uptake and Soil Parameters
Nickel Uptake and Pollution
Nickel Tolerance
Nickel-Accumulating Plants
Phytochemistry of Nickel-Accumulating Plants / 8.:
Future Outlook / 9.:
Nickel Metabolism in Man and Animals / Evert Nieboer ; Rickey T. Tom ; W. (Bill) E. SanfordChapter 4:
Routes of Nickel Absorption
Distribution of Nickel
Nickel Transport and Cellular Uptake
Nickel Biochemistry
Routes of Elimination
Nickel as an Essential Element
Concluding Remarks and Summary
Abbreviations
Nickel Ion Binding to Amino Acids and Peptides / R. Bruce MartinChapter 5:
The Setting
Amino Acid Complexes
Citrate Complexes
Peptide Complexes
Nickel in Proteins and Enzymes / Robert K. Andrews ; Robert L. Blakeley ; Burt ZernerChapter 6:
Nickel in Biology
Nickel-Binding Proteins
Enzymes and Metal Ions
Metal Ion Catalysis
Some Properties of Nickel Complexes
Nickel(II) Catalysis in Model Systems
Nickel(II)-Activated Enzymes
Binding Sites for Metal Ions
Nickel(III) Enzymes / 10.:
Nickel(II) Metalloenzymes: Urease / 11.:
Conclusion / 12.:
Nickel-Containing Hydrogenases / Jose J. G. Moura ; Isabel Moura ; Miguel Teixeira ; Antonio V. Xavier ; Guy D. Fauque ; Jean LeGallChapter 7:
Nickel Involvement in Hydrogenases
Spectroscopic Tools and Instrumental Probes: Isotopic Substitutions
Active Center Composition: Types of Hydrogenases
Cell Localization of Hydrogenases: Existence of Multiple Forms and Genetic Information
EPR and Mossbauer Studies: Nickel and [FeS] Centers
Midpoint Redox Potentials
Nickel Site Coordination
Discussion of a Mechanistic Framework for the Nickel-Containing Hydrogenases
Abstract
Note Added in Proof
Nickel Ion Binding to Nucleosides and Nucleotides / Chapter 8:
Binding to Bases and Nucleosides
Binding to Nucleotides
Interactions between Nickel and DNA: Considerations about the Role of Nickel in Carcinogenesis / E. L. Andronikashvili ; V. G. Bregadze ; J. R. MonaselidzeChapter 9:
Nickel(II) Interaction with DNA
Nickel and Nucleoproteins
In Vivo Influence of Nickel(II) on the Thermal Properties of Chromatin Inside the Nuclei, and on Cells and Tissues of Normal and Tumorous Origin
Nickel(II) Incorporation in DNA and the Role of Nickel in Carcinogenesis
Toxicology of Nickel Compounds / Franco E. Rossetto ; C. Rajeshwari MenonChapter 10:
Human Exposures
Nickel Carbonyl Poisoning
Nickel Hypersensitivity
Nickel Carcinogenesis
Genetic Toxicology
Miscellaneous Health Effects
Analysis of Nickel in Biological Materials / Hans G. SeilerChapter 11:
General Aspects of Analyses of Nickel in Biological Materials
Choice of Implements and Chemicals
Specimen Collection; Sampling
Sample Preparation
Determination Methods
Author Index
Subject Index
Preface to the Series
Preface to Volume 23
Contributors
4.

図書

図書
Sigel, Helmut
出版情報: New York : Dekker, c1985  xxvi, 429 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 19
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Preface to the Series
Preface to Volume 19
Contributors
Contents of Other Volumes
The Discovery of Ionophores: An Historical Account / Berton C. PressmanChapter 1:
Abbreviations
References
Tetracyclines and Daunorubicin / R. Bruce MartinChapter 2:
Introduction / 1.:
Tetracyclines / 2.:
Daunorubicin / 3.:
Interaction of Metal Ions with Streptonigrin and Biological Properties of the Complexes / Joseph HajduChapter 3:
Structural and Chemical Properties of Streptonigrin and Its Metal Complexes
Biological Activity and Suggested Mechanistic Schemes for the Antitumor Action of Streptonigrin
Conclusions / 4.:
Bleomycin Antibiotics: Metal Complexes and Their Biological Action / Yukio Sugiura ; Tomohisa Takita ; Hamao UmezawaChapter 4:
Structural and Synthetic Aspects of Bleomycin
Characteristics of Bleomycin-Metal Complexes
Oxygen Activation and Redox Cycle of the Bleomycin-Iron Complex
Interaction of Bleomycin and Its Iron Complex with DNA / 5.:
Sequence-Specific DNA Cleavage by the Bleomycin-Iron Complex / 6.:
Metal Complexes and DNA Cleavage of Bleomycin Analogs: Peplomycin, Tallysomycin, and Phleomycin / 7.:
Metal Complexes and Oxygen Activation by Synthetic Analogs and Biosynthetic Intermediates of Bleomycin / 8.:
Molecular Mechanism of Bleomycin Action / 9.:
Interaction Between Valinomycin and Metal Ions / K. R. K. Easwaran10.:
Structure and Conformation of Free Valinomycin
Structure and Conformation of Valinomycin-Metal Ion Complexes
Valinomycin-Metal Ion Complexes in Transmembrane Ion Transport
Abbreviations and Definitions
Beauvericin and the Other Enniatins / Larry K. SteinraufChapter 6:
Ion Binding
Membrane Transport
Analogs
Complexing Properties of Gramicidins / James F. Hinton ; Roger E. Koeppe IIChapter 7:
Structural Properties
Ion-Complexing Properties
Transport Properties
Nactins: Their Complexes and Biological Properties / Yoshiharu Nawata ; Kunio Ando ; Yoichi IitakaChapter 8:
Molecular Structure of Nactins
Complexes
Biological Properties
Cation Complexes of the Monovalent and Polyvalent Carboxylic Ionophores: Lasalocid (X-537A), Monensin, A23187 (Calcimycin), and Related Antibiotics / George R. PainterChapter 9:
Structure of Ionophore-Cation Inclusion Complexes
Techniques for Measuring Equilibrium Ionophore-Ion Affinities
Carboxylic Ionophore-Mediated Ion Transport
Biological Test Systems
Conformational Aspects of Ion Capture and Membrane Transport
Biological Applications of Ionophores
Overview
Complexes of D-Cycloserine and Related Amino Acids with Antibiotic Properties / Paul O'BrienChapter 10:
Mode of Action
Uses of D-Cycloserine
Organic Chemistry of D-Cycloserine
Metal Ion Coordination by D-Cycloserine
Metal Ion Coordination by D-Cycloserine Derivatives
Iron-Containing Antibiotics / J. B. Neilands ; J. R. ValentaChapter 11:
Iron(III) Complexes
Iron(II) Complexes
Miscellaneous Compounds
General Conclusions
Cation-Ionophore Interactions: Quantification of the Factors Underlying Selective Complexation by Means of Theoretical Computations / Nohad Gresh ; Alberte PullmanChapter 12:
Outline of the Methodology
Selective Binding of Alkali Cations by Valinomycin
Selective Complexation of K[superscript +], Na[superscript +], and NH[superscript + subscript 4] by Nonactin
Selective Binding of Mg[superscript 2+] and Ca[superscript 2+] by Ionophore A23187
Structural Properties of Valinomycin and A23187
Energy Profiles for Single and Double Occupancy by Na[superscript +] of the Gramicidin A Channel
Author Index
Subject Index
Preface to the Series
Preface to Volume 19
Contributors
5.

図書

図書
edited by Helmut Sigel with the assistance of Astrid Sigel
出版情報: New York : Dekker, c1986  xxiv, 386 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 20
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Preface to the Series
Preface to Volume 20
Contributors
Contents of Other Volumes
Distribution of Potentially Hazardous Trace Metals / Garrison SpositoChapter 1:
Introduction / 1.:
Distribution of Trace Metals in the Atmosphere, Hydrosphere, and Lithosphere / 2.:
Metal Enrichment and Transfer / 3.:
References
Bioinorganic Chemistry of Metal Ion Toxicity / R. Bruce MartinChapter 2:
Essentiality and Toxicity
Properties of Metal Ions
Survey of Metal Ions / 4.:
Caveat / 5.:
The Interrelation Between Essentiality and Toxicity of Metals in the Aquatic Ecosystem / Elie EichenbergerChapter 3:
General Introduction
Essential Metals
Uptake and Incorporation of Metals
Toxicity as a Result of Oversupply of Essential Metals
Tolerance to Metals
Effect of Essential Metals on Aquatic Communities / 6.:
Conclusions and Outlook / 7.:
Metal Ion Speciation and Toxicity in Aquatic Systems / Gordon K. PagenkopfChapter 4:
Chemical Model
Application to Copper Toxicity
Application to Cadmium Toxicity
Application to Lead Toxicity
Application to Zinc Toxicity
Conclusion
Abbreviations and Definitions
Metal Toxicity to Agricultural Crops / Frank T. Bingham ; Frank J. Peryea ; Wesley M. JarrellChapter 5:
Cadmium
Copper
Zinc
Manganese
Nickel
Metal Ion Toxicity in Man and Animals / Paul B. Hammond ; Ernest C. FoulkesChapter 6:
Lead
Arsenic
Vanadium
Mercury
Chromium / 8.:
Uranium / 9.:
Conclusions / 10.:
Human Nutrition and Metal Ion Toxicity / M. R. Spivey Fox ; Richard M. JacobsChapter 7:
Nutrient Intake and Nutritional Status in the United States
Selenium
General Conclusions
Chromosome Damage in Individuals Exposed to Heavy Metals / Alain LeonardChapter 8:
Production of Cytogenetic Changes in Peripheral Blood Lymphocytes
Results of the Cytogenetic Monitoring Performed on Persons Exposed to Heavy Metals
General Discussion
Metal Ion Carcinogenesis: Mechanistic Aspects / Max Costa ; J. Daniel HeckChapter 9:
Cellular Uptake and Intracellular Distribution of Metal Ions
DNA Lesions Produced by Carcinogenic Metals
Effect of Metal Ions on Cell Growth, DNA Replication, and DNA Repair
Tumor-Promoting Activity of Metals and the Relationship between Mutagenesis and Carcinogenesis
Inhibition of Transformation and Carcinogenesis by Divalent Metal Ions
Methods for the in Vitro Assessment of Metal Ion Toxicity / Chapter 10:
Biochemical Methods
Microbiological Methods
Mammalian Cell Culture Methods
Some Problems Encountered in the Analysis of Biological Materials for Toxic Trace Elements / Hans G. SeilerChapter 11:
General Aspects of Trace Element Analysis
Choice of Implements and Chemicals
Specimen Collection
Storage, Drying, and Homogenization
Sample Aliquotation and Sampling
Sample Preparation
Author Index
Subject Index
Preface to the Series
Preface to Volume 20
Contributors
6.

図書

図書
edited by Helmut Sigel, with Astrid Sigel
出版情報: New York : M. Dekker, c1988  xxix, 424 p. ; 25 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 24
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7.

図書

図書
edited by Helmut Sigel, with the assistance of Astrid Sigel
出版情報: New York : M. Dekker, c1981  xx, 353 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 12
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8.

図書

図書
edited by Helmut Sigel, with the assistance of Astrid Sigel
出版情報: New York : M. Dekker, c1981  xx, 394 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 13
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Phosphate-metal ion interactions of nucleotides and polynucleotides
sugar-metal ion interactions
dichotomy of metal ion binding to N1 and N7 of purines
general conclusions from sold state studies of nucleotide-metal ion complexes
solution studies of nucleotide-metal ion complexes - isomeric equilibria
stacking interactions involving nucleotides and metal ion complexes
the effect of metal ions on hydrolytic reactions of nucleotides and their phosphoesters
metal complexes of from
Phosphate-metal ion interactions of nucleotides and polynucleotides
sugar-metal ion interactions
dichotomy of metal ion binding to N1 and N7 of purines
9.

図書

図書
edited by Helmut Sigel with Astrid Sigel
出版情報: New York : M. Dekker, c1982  xxi, 360 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 14
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10.

図書

図書
edited by Helmut Sigel with Astrid Sigel
出版情報: New York : M. Dekker, c1989  xxxiii, 557 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 25
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