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1.

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EB
Michael Smith
出版情報: Elsevier ScienceDirect Books , Academic Press, 2010
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Retrosynthesis, Stereochemistry, and Conformations
Acids, Bases and Functional Group Exchange Reactions
Oxidation
Reduction
Hydroboration
Stereocontrol and Ring Formation
Protecting Groups
Cd Disconnect Products: Nucleophilic Species That Form Carbon-Carbon Bonds
Cd Disconnect Products: Nucleophilic Species That Form Carbon-Carbon Bonds: Enolate Anions
Synthetic Strategies
Pericyclic Carbon-Carbon Bond Forming Reactions: Multiple Bond Disconnections
Ca Disconnect Products: Electrophilic Carbon-Carbon Bond Forming Reactions
Carbon Radical Disconnect Products: Formation of Carbon-Carbon Bonds Via Radicals and Carbenes
Student Syntheses: The First Synthetic Problem
Disconnection Index
General Index
Instructions and code to access SPartan software
Retrosynthesis, Stereochemistry, and Conformations
Acids, Bases and Functional Group Exchange Reactions
Oxidation
2.

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EB
James R. Couper, PhD, James R. Fair, W. Roy Penney
出版情報: Elsevier ScienceDirect Books , Butterworth-Heinemann, 2010
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Rules of Thumb Summary / Chapter 0:
Introduction / Chapter 1:
Flowsheets / Chapter 2:
Process Control / Chapter 3:
Drivers for Moving Equipment / Chapter 4:
Transfer of Solids / Chapter 5:
Flow of Fluids / Chapter 6:
Fluid Transport Equipment / Chapter 7:
Heat Transfer and Heat Exchangers / Chapter 8:
Dryers and Cooling Towers / Chapter 9:
Mixing and Agitation / Chapter 10:
Solid-Liquid Separation / Chapter 11:
Disintegration, Agglomeration and Size Separation / Chapter 12:
Distillation and Gas Absorption / Chapter 13:
Extraction and Leaching / Chapter 14:
Adsorption and Ion Exchange / Chapter 15:
Crystallization from Solutions and Melts / Chapter 16:
Chemical Reactors / Chapter 17:
Process Vessels / Chapter 18:
Membrane Separations / Chapter 19:
Gas-Solid Separations / Chapter 20:
Costs of Individual Equipment / Chapter 21:
Rules of Thumb Summary / Chapter 0:
Introduction / Chapter 1:
Flowsheets / Chapter 2:
3.

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Philippe M. Soriano, Paul M. Wassarman
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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General Resources / Section I:
A survey of internet resources for mouse development / Thomas L. Saunders1:
Handling Mouse Lines / Section II:
Transport of mouse lines by shipment of live embryos / Kevin A. Kelley2:
Strategies and considerations for distributing and recovering mouse lines / Yubin Du ; Wen Xie ; Chengyu Liu3:
Archiving and distributing mouse lines by sperm cryopreservation, IVF, and embryo transfer / Hideko Takahashi4:
Gametes and Embryos / Section III:
Isolation and manipulation of mouse gametes and embryos / Eveline S. Litscher ; Paul M. Wassarman5:
Cryopreservation of mouse gametes and embryos / Carlisle P. Landel6:
Ovarian follicle culture systems for mammals / David F. Albertini ; Gokhan Akkoyunlu7:
Production of mouse chimaeras by aggregating pluripotent stem cells with embryos / Andras Nagy ; Kristina Nagy ; Marina Gertsenstein8:
Production of cloned mice from somatic cells, ES cells, and frozen bodies / Sayaka Wakayama ; Eiji Mizutani ; Teruhiko Wakayama9:
Nuclear transfer in mouse oocytes and embryos / Zhiming Han ; Yong Cheng ; Cheng-Guang Liang ; Keith E. Latham10:
Culture of whole mouse embryos at early post-implantation to organogenesis stages: developmental staging and methods / Jaime A. Rivera-Perez ; Vanessa Jones ; Patrick P. L. Tam11:
In utero and ex utero surgery on rodent embryos / Valerie Ngo-Muller ; Ken Mueoka12:
Fertilization / Section IV:
Enhancement of IVF in the mouse by zona-drilling / 13:
ICSI in the mouse / Paula Stein ; Richard M. Schultz14:
ES and iPS Cells / Section V:
A simple procedure for the efficient derivation of mouse ES cells / Esther Wong ; Kenneth Ban ; Rafidah Mutalif ; Nancy A. Jenkins ; Neal G. Copeland ; Colin L. Stewart15:
Producing fully ES cell-derived mice from 8-cell stage embryo injections / Thomas M. DeChiara ; William T. Poueymirou ; Wojtek Auerbach ; David Frendewey ; George D. Yancopoulos ; David M. Valenzuela16:
The loss-of-allele assay for ES cell screening and mouse genotyping / Rostislav Chernomorsky ; Lakeisha Esau ; Jinsop Om ; Yingzi Xue ; Andrew J. Murphy17:
Induced pluripotent stem (iPS) cells / Holm Zaehres ; Jeong Beom Kim ; Hans R. Schöler18:
Imaging Mouse Development / Section VI:
Imaging mouse embryonic development / Ryan S. Udan ; Mary E. Dickinson19:
Imaging mouse development with confocal time-lapse microscopy / Sonja Nowotschin ; Anna Ferrer-Vaquer ; Anna-Katerina Hadjantonakis20:
Ultrasound and magnetic resonance microimaging of mouse development / Brian J. Nieman ; Daniel H. Turnbull21:
Hematopoiesis / Section VII:
Use of transgenic fluorescent reporter mouse lines to monitor hematopoietic and erythroid development during embryogenesis / Stuart T. Fraser ; Joan Isern ; Margaret H. Baron22:
Identification and in vivo analysis of murine hematopoietic stem cells / Serine Avagyan ; Yacine M. Amrani ; Hans-Willem Snoeck23:
General Resources / Section I:
A survey of internet resources for mouse development / Thomas L. Saunders1:
Handling Mouse Lines / Section II:
4.

電子ブック

EB
Grant Jensen, Grant J. Jensen
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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Historical perspective 3D reconstruction from electron micrographs: a personal account of its development / David DeRosier
Preparation of 2-D crystals / Henning Stahlberg
Helical Crystallization of Soluble and Membrane Binding Proteins / Elizabeth M. Wilson-Kubalek ; Christopher Arthur ; Joshua S. Chappie
Plunge Freezing for Electron Cryomicroscopy / Alasdair W. McDowall ; Megan J. Dobro ; Linda A. Melanson ; Grant J. Jensen
A Practical Guide to the Use of Monolayer Purification and Affinity Grids / Thomas Walz ; Deborah F. Kelly ; Danijela Dukovski
GraFix: Stabilization of fragile macromolecular complexes for single Particle cryo-EM / Holger Stark
Cryo-negative staining of macromolecular assemblies / Sacha De Carlo
Liposomes on a streptavidin crystal: a system to study membrane proteins by cryo-EM / Fred J. Sigworth ; Liguo Wang
Micromanipulator-Assisted Vitreous Cryosectioning and Sample Preparation by High-Pressure Freezing / Mark S. Ladinsky
Site-Specific Biomolecule Labeling with Gold Clusters / Christopher J. Ackerson ; Richard D. Powell ; James F. Hainfeld
How to Operate a Cryo-Electron Microscope / Huilin Li ; Jingchuan Sun
Collecting electron crystallographic data of two-dimensional protein crystals / Richard K. Hite ; Andreas D. Schenk ; Zongli Li ; Yifan Cheng
Automated Data Collection for Electron Microscopic Tomography / David Agard ; Shawn Q. Zheng ; J. W. Sedat
Correlated Light and Electron Cryomicroscopy / Ariane Briegel ; Songye Chen ; Abraham J. Kosterc ; Jürgen M. Plitzkod ; Cindi L. Schwartz
Phase Plates for Transmission Electron Microscopy / Radostin Danev ; Kuniaki Nagayama
Radiation damage in electron cryomicroscopy / John L. Rubinstein ; Lindsay A. Baker
Historical perspective 3D reconstruction from electron micrographs: a personal account of its development / David DeRosier
Preparation of 2-D crystals / Henning Stahlberg
Helical Crystallization of Soluble and Membrane Binding Proteins / Elizabeth M. Wilson-Kubalek ; Christopher Arthur ; Joshua S. Chappie
5.

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EB
Nils G. Walter
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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Contributors
Preface
Volume in Series
Star Polymer Surface Passivation for Single-Molecule Detection / Jürgen Groll ; Martin Moeller1:
Introduction
Surface Grafting of PEO and Protein Repellence / 2:
The NCO-sP(EO-stat-PO) System / 3:
Preparation of sP(EO-stat-PO)-Coated Substrates for Single-Molecule Experiments / 4:
Analysis of Protein Structure and Function on NCO-sP(EO-stat-PO) Surfaces / 5:
Acknowledgments
References
Azide-Specific Labeling of Biomolecules by Staudinger-Bertozzi Ligation: Phosphine Derivatives of Fluorescent Probes Suitable for Single-Molecule Fluorescence Spectroscopy / Anirban Chakraborty ; Dongye Wang ; Yon W. Ebright ; Richard H. Ebright
Materials and Methods
Preparation of Fluorescent Pre-mRNA Substrates for an smFRET Study of Pre-mRNA Splicing in Yeast / John Abelson ; Haralambos Hadjivassiliou ; Christine Guthrie
Identification of a Yeast Pre-mRNA with a Small Intron that is Spliced Efficiently In Vitro
Synthetic Fluorescent Ubc4 Pre-mRNA
Do the Dyes Affect the Efficiency of Splicing?
Mutant Pre-mRNAs
Tethering the Pre-mRNA to the Microscope Slide / 6:
Summary and Conclusion / 7:
Nanovesicle Trapping for Studying Weak Protein Interactions by Single-Molecule FRET / Jaime J. Benítez ; Aaron M. Keller ; Peng Chen
Nanovesicle Trapping Approach
smFRET Measurements of Weak Protein-Protein Interactions
Single-Molecule Kinetic Analysis of Three-State Protein-Protein Interactions
Further Developments
Concluding Remarks
Droplet Confinement and Fluorescence Measurement of Single Molecules / Lori S. Goldner ; Ana M. Jofre ; Jianyong Tang
Methods for Droplet Generation
Methods for Droplet Manipulation
Droplet Coalescence and Mixing
Experimental Considerations for Single Fluorophore Detection
Single-Molecule Measurements in Droplets
Future Prospects
Single-Molecule Fluorescence Spectroscopy Using Phospholipid Bilayer Nanodiscs / Abhinav Nath ; Adam J. Trexler ; Peter Koo ; Andrew D. Miranker ; William M. Atkins ; Elizabeth Rhoades
Nanodiscs and HDL Particles
Single-Molecule Techniques and Applications to Membrane Proteins
Cytochrome P450 3A4 and Its Allosteric Behavior
Image Filtering by Singular-Value Decomposition
Islet Amyloid Polypeptide Binding to Nanodiscs
?-Synuclein Conformations on Nanodiscs
Summary / 8:
Single-Molecule Spectroscopy Using Microfluidic Platforms / Samuel Kim ; Richard N. Zare
Microchip Fabrication
Instrumentation for Fluorescence Detection
Detergent-Assisted Microchannel Electrophoresis
Fluorescence Correlation Spectroscopy
Detection of Protein-Protein Interactions in the Live Cell Plasma Membrane by Quantifying Prey Redistribution upon Bait Micropatterning / Julian Weghuber ; Mario Brameshuber ; Stefan Sunzenauer ; Manuela Lehner ; Christian Paar ; Thomas Haselgrübler ; Michaela Schwarzenbacher ; Martin Kaltenbrunner ; Clemens Hesch ; Wolfgang Paster ; Bettina Heise ; Alois Sonnleitner ; Hannes Stockinger ; Gerhard J. Schütz
Methodological Requirements
The Micropatterning Technique
Experimental Design
Procedure
Interpretation of Results
Figures of Merit
Conclusions
Analysis of Complex Single-Molecule FRET Time Trajectories / Mario Blanco ; Nils G. Walter9:
Analysis of Simple Trajectories
Analysis of Complex Trajectories
Post-HMM Processing and Data Visualization
Acknowledgment
Single-Molecule Fluorescence Studies of Intrinsically Disordered Proteins / Allan Chris M. Ferreon ; Crystal R. Moran ; Yann Gambin ; Ashok A. Deniz10:
Single-Molecule Fluorescence Methods
Site-Specific Labeling of Intrinsically Disordered Proteins
Examples of SMF Characterization of IDP Structure and Dynamics
Measuring the Energetic Coupling of Tertiary Contacts in RNA Folding using Single Molecule Fluorescence Resonance Energy Transfer / Max Greenfeld ; Daniel Herschlag11:
Thermodynamic Cooperativity Overview
Measuring Folding Equilibrium in RNA
Designing an smFRET Experiment to Measure Cooperativity
Additional Comments
A Highly Purified, Fluorescently Labeled In Vitro Translation System for Single-Molecule Studies of Protein Synthesis / Jingyi Fei ; Jiangning Wang ; Samuel H. Sternberg ; Daniel D. MacDougall ; Margaret M. Elvekrog ; Dileep K. Pulukkunat ; Michael T. Englander ; Ruben L. Gonzalez Jr12:
A Highly Purified, Escherichia coli-Based In Vitro Translation System
Biochemical Assays
Preparation of Fluorescently Labeled Translation Components
Conclusions and Future Perspectives
Watching Individual Proteins Acting on Single Molecules of DNA / Ichiro Amitani ; Bian Liu ; Christopher C. Dombrowski ; Ronald J. Baskin ; Stephen C. Kowalczykowski13:
Preparation of DNA Substrates
Preparation of Fluorescent Proteins
Instrument
Single-Molecule Imaging of Proteins on DNA
Data Analysis Methods
DNA Curtains for High-Throughput Single-Molecule Optical Imaging / Eric C. Greene ; Shalom Wind ; Teresa Fazio ; Jason Gorman ; Mari-Liis Visnapuu14:
Total Internal Reflection Fluorescence Microscopy
DNA Curtains
Visualizing Protein-DNA Interactions
Conclusions and Future Directions
Scanning FCS for the Characterization of Protein Dynamics in Live Cells / Zdenek Petrásek ; Jonas Ries ; Petra Schwille15:
Implementation
Data Analysis
Applications
Conclusion
Observing Protein Interactions and Their Stoichiometry in Living Cells by Brightness Analysis of Fluorescence Fluctuation Experiments / Yan Chen ; Jolene Johnson ; Patrick Macdonald ; Bin Wu ; Joachim D. Mueller16:
Brightness Classification of Fluorescent Molecules
Brightness Measurements in Cells
Detection of Individual Endogenous RNA Transcripts In Situ Using Multiple Singly Labeled Probes / Arjun Raj ; Sanjay Tyagi17:
Design and Synthesis of Fluorescent Oligonucleotide Probe Sets
Preparation of Samples for In Situ Hybridization
Hybridization
Imaging
Image Analysis
Single mRNA Tracking in Live Cells / Hye Yoon Park ; Adina R. Buxbaum ; Robert H. Singer18:
Significance of Tracking mRNA
Labeling mRNA in Living Cells
Imaging mRNA Movements
Analyzing mRNA Motions
Single-Molecule Sequencing: Sequence Methods to Enable Accurate Quantitation / Christopher Hart ; Doron Lipson ; Fatih Ozsolak ; Tal Raz ; Kathleen Steinmann ; John Thompson ; Patrice M. Milos19:
Basic Principles of Single-Molecule Sequencing
Preparation of Genomic DNA for Single-Molecule Sequencing
Bacterial Genome Sequencing
Human Genome Sequencing and Quantitation
Chromatin Immunoprecipitation Studies
Digital Gene Expression for Transcriptome Quantitation
Real-Time DNA Sequencing from Single Polymerase Molecules / Jonas Korlach ; Keith P. Bjornson ; Bidhan P. Chaudhuri ; Ronald L. Cicero ; Benjamin A. Flusberg ; Jeremy J. Gray ; David Holden ; Ravi Saxena ; Jeffrey Wegener ; Stephen W. Turner20:
Principle of Single-Molecule, Real-Time DNA Sequencing
Components of SMRT Sequencing
Single-Molecule DNA Polymerase Dynamics
Author index
Subject Index
Contributors
Preface
Volume in Series
6.

電子ブック

EB
John N. Abelson, Gerald R. Fink, Christine Guthrie, Melvin I. Simon, Jonathan Weissman
出版情報: Elsevier ScienceDirect Books , Elsevier Science, 2010
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Functional Genomics / Part I:
Analysis of Gene Function using DNA Microarrays / Andrew P. Capaldi1:
An introduction to microarray data analysis and visualization / Gregg B. Whitworth2:
Genome-wide approaches to monitor pre-mRNA splicing / Maki Inada ; Jeff Pleiss3:
ChIP-Seq: Using high-throughput DNA sequencing for genome-wide identification of transcription factor binding sites / Philippe Lefrançois ; Wei Zheng ; Michael Snyder4:
Genome-wide mapping of nucleosomes in yeast / Oliver J. Rando5:
Genome-wide translational profiling by ribosome footprinting / Nicholas T. Ingolia6:
Systematic Genetic Analysis / Part II:
Synthetic Genetic Array (SGA) Analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe / Anastasia Baryshnikova ; Michael Costanzo ; Scott Dixon ; Franco J. Vizeacoumar ; Chad L. Myers ; Brenda Andrews ; Charles Boone7:
Making temperature-sensitive mutants / Shay Ben-Aroya ; Xuewen Pan ; Jef D. Boeke ; Philip Hieter8:
Quantitative Genetic Interaction Mapping using the E-MAP Approach / Sean R. Collins ; Assen Roguev ; Nevan J. Krogan9:
Exploring gene function and drug action using chemogenomic dosage assays / Elke Ericson ; Shawn Hoon ; Robert P. St. Onge ; Guri Giaever ; Corey Nislow10:
Proteomics / Part III:
Yeast Expression Proteomics by High-Resolution Mass Spectrometry / Tobias C. Walther ; Jesper V. Olsen ; Matthias Mann11:
High-quality binary interactome mapping / Matija Dreze ; Dario Monachello ; Claire Lurin ; Michael E. Cusick ; David E. Hill ; March Vidal ; Pascal Braun12:
Quantitative analysis of protein phosphorylation on a system-wide scale by mass spectrometry based proteomics / Bernd Bodenmiller ; Rudi Aebersold13:
A Toolkit of Protein-fragment Complementation Assays for Studying and Dissecting Large-scale and Dynamic Protein-Protein Interactions in Living Cells / Stephen W. Michnick ; Po-Hien Ear ; Christian Landry ; Mohan K. Malleshaiah ; Vincent Messier14:
Yeast Lipid Analysis and Quantification by Mass Spectrometry / Xue Li Guan ; Isabelle Riezman ; Markus R. Wenk ; Howard Riezman15:
Mass Spectrometry-Based Metabolomics of Yeast / Christopher A. Crutchfield ; Wenyun Lu ; Eugene Melamud ; Joshua D. Rabinowitz16:
Systems Analysis / Part IV:
Imaging single mRNA molecules in yeast / Hyun Youk ; Arjun Raj ; Alexander van Oudenaarden17:
Reconstructing gene histories in Ascomycota fungi / IlanWapinski ; Aviv Regev18:
Experimental evolution in yeast: a practical guide / Maitreya J. Dunham19:
Synthetic Biology / Part V:
Enhancing stress resistance and production phenotypes through transcriptome engineering / Felix H. Lam ; Franz S. Hartner ; Gerald R. Fink ; Gregory Stephanopoulos20:
Advances in Cytology/Biochemistry / Part VI:
Visualizing yeast chromosomes and nuclear architecture / Peter Meister ; Lutz R. Gehlen ; Elisa Varela ; Veronique Kalck ; Susan M. Gasser21:
Quantitative localization of chromosomal loci by immunofluorescence / Donna Garvey Brickner ; William Light ; Jason H. Brickner22:
Spinning Disk Confocal Microscopy of Yeast / Kurt Thorn23:
Correlative GFP-immunoelectron microscopy in yeast / Christopher Buser ; Kent McDonald24:
Analyzing P-bodies and stress granules in Saccharomyces cerevisiae / J Ross Buchan ; Tracy Nissan ; Roy Parker25:
Analyzing mRNA expression using single mRNA resolution fluorescent in situ hybridization / Daniel Zenklusen ; Robert H Singer26:
The Use of In Vitro Assays to Measure Endoplasmic Reticulum Associated Degradation (ERAD) / Jeffrey L. Brodsky27:
A protein transformation protocol for introducing yeast prion Particles into yeast / Motomasa Tanaka28:
Overexpression and Purification of Integral Membrane Proteins in Yeast / Franklin A. Hays ; Zygy Roe-Zurz ; Robert M. Stroud29:
Biochemical, cell biological and genetic assays to analyze amyloid and prion aggregation in yeast / Simon Alberti ; Randal Halfmann ; Susan Lindquist30:
Other Fungi / Part VII:
Genetics and Molecular Biology in Candida albicans / Hernday, A.D. ; Noble, S. M. ; Mitrovich, Q.M. ; Johnson, A.D31:
Molecular Genetics of Schizosaccharomyces pombe / Sarah A. Sabatinos ; Susan L. Forsburg32:
Applying Genetics and Molecular Biology to the Study of the Human Pathogen Cryptococcus neoformans / Cheryl D. Chun ; Hiten D. Madhani33:
The Fungal Genome Initiative and lessons learned from genome sequencing / Christina A. Cuomo ; Bruce W. Birren34:
Ultradian metabolic cycles in yeast / Benjamin Tu35:
Functional Genomics / Part I:
Analysis of Gene Function using DNA Microarrays / Andrew P. Capaldi1:
An introduction to microarray data analysis and visualization / Gregg B. Whitworth2:
7.

電子ブック

EB
Minoru Fukuda
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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Stem Cell / Section I:
ß1,4-galactosyltransferase V in growth regulation / Jianxin Gu1:
Roles of Polysialic acid in neural stem cells / Kiyohiko Angata2:
Chondroitin sulfate in neural stem cells / Andreas Faissner3:
Transcription in Stem Cell / Kelly Moremen4:
Directing stem cell trafficking through GPS / Robert. Sackstein5:
Gene knockout and mutant mice / Section II:
Cosmc-chaperone / Richard Cummings Ju6:
Core 3 O-glycan / Lijuan Xia7:
Core3 glycan as tumor suppressor / Lee Fukuda8:
Core 4 O-glycan / Jamey Marth ; Minoru Fukuda9:
b3GlcNAcT2, a major polylacosamine synthase / Akira. Togayachi ; Hisashi Narimatsu10:
GalNAcT-1 / Mari Tenno. Jamey Marth11:
GlcNAcT-IVa-Diabetes / Kazuaki Ohtsubo12:
Ashwell receptor / Prabhijt. Grewal13:
Roles ofGlcNAc-6-O-sulfotransferases in lymphoid and non-lymphoid tissues Hiroto Kawashima / 14:
ß3GlcNAcT3-core 2GlCNAcT1-selectin ligand / Junya. Mitoma15:
ManII-ManIIX / Michiko Fukuda16:
Histochemical analysis carbohydrate antigens in inflammation / Motohiro Kobayashi ; Jun Nakayama17:
Alpha-Dystroglycan and tumor / Section III:
Genetic defect in muscular dystrophy / Paul Martin18:
POMT1 knockout / Sabine Strahl ; Jesus Cruces19:
POMGnT1 Mutation in human / Tamao ; Endo20:
POMGnT1 Knockout mice / Huaiyu Hu21:
Large mutation and Large 2 / Jane. Hewitt22:
a-dystroglycan glycans as tumor suppressor / Xingfeng Bao23:
Tumor formation assay / Shingo Hatakeyama ; Chikara Ohyama24:
Stem Cell / Section I:
ß1,4-galactosyltransferase V in growth regulation / Jianxin Gu1:
Roles of Polysialic acid in neural stem cells / Kiyohiko Angata2:
8.

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EB
Minoru Fukuda
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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Proteoglycans and Sulfotransferases / Section I:
3-O-sulfotransferases / Nicholas Scworak1:
Proteoglycan and signal transduction / Michael Simon2:
Glypican function / Xinhua Lin3:
Glycomics profiling of heparan sulfate / Jeremy Turnbull4:
Infection and lectin / Section II:
Recognition of carbohydrates by natural killer T cells / Mitch Kronenberg5:
Microbial glycoconjugates in innate immunology / Antonio Molinaro6:
Schistosome glycolipids and their role in innate immunity / Irma Van Die ; Rudolf Guyer7:
Carbohydrate-specific signaling through the DC-SIGN / Teunis Geijtenbeek8:
Natural and engineered carbohydrate-recognition domains for targeted glycoproteomic analysis of cell surface glycosylation and identification of ligands for glycan-binding receptors / Kurt Drickamer9:
MRH-domain containing lectin ERAD / Nobuko Hirosawa10:
Galectin and the control of immune tolerance / Gabriel Rabinovich11:
Galectin and cell signaling / Michel Demetriou12:
Galectin-1 and HIV infection / Sachiko Sato13:
Drosophila / Secion III:
Drosophila N- and O-glycans / Michael Tiemeyer14:
Drosophila proteoglycans / Shoko Nishihara15:
Notch Signaling / Section IV:
O-GlcNAc modification of EGF domain of notch / Tetsuya Okajima17:
Regulation of Notch signaling via O-glycosylation / Jafar-Nejad Hamed18:
New Development / Section V:
O-fucosylation of Thrombospondin type 1 repeats / Robert Haltiwanger19:
Unique glycans attached to unique glycoproteins / Michael Pierce20:
Autoantibodies against carbohydrates / Michel Hollingsworth21:
GPRH is critical for Golgi apparatus function / Yusuke Maeda ; Taroh Kinoshita22:
Genome-wide RNAi screen for N-glycosylation loci / Weston B Struwe23:
Fucosyl glycans that bind to Helicobacter pylori / Tatsuo Miyazaki ; Katsumi Ajisaka24:
Seven-pass transmembrane glycoprotein, a glucose-responding receptor / Yoshio Hirabayashi25:
Proteoglycans and Sulfotransferases / Section I:
3-O-sulfotransferases / Nicholas Scworak1:
Proteoglycan and signal transduction / Michael Simon2:
9.

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EB
Minoru Fukuda
出版情報: Elsevier ScienceDirect Books , Burlington : Elsevier Science, 2010
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Glycomics / Section I:
Mass spectrometric analysis of acidic oligosaccharides / K-H. Khoo1:
Mass Spectrometric Analysis of mutant mice / Anne Dell2:
Electrospray mass spectrometry including ESI FTICR-MS / Robert Linhardt3:
Mass spectrometric data base for N-glycan and O-glycan / H. Narimatsu4:
Mass spectrometric analysis of cancer-associated N-glycans / Shinichiro Nishimura5:
Fucosylation as cancer marker / Eiji Miyoshi6:
Development of lectin microarray for glycan profiling and its application to disease-related biomarker development / Jun Hirabayashi ; Atsushi Kuno7:
Cellular glycomics and versatile applications of lectin microarray / Jul Hirabayashi ; Hiroaki Tateno8:
Carbohydrate-binding protein array / Richard Cummings ; David Smith9:
Detection of weak binding sugar activity using membrane-based carbohydrates / Kazuo Yamamoto10:
Binding to synthetic glycopeptides / Anne Lepannen11:
Glycan array and Malectin / Ten Feizi12:
Imaging mass spectrometry / Naoko Goto-Inoue13:
Chemical Glycobiology / Section II:
NMR / Yoshiki Yamaguchi14:
Self/non-self recognition / Koichi Fukase15:
Multivalent ligand for CD22 / Mary O'Reilly ; Jim Paulson16:
Intramolecular interaction / David Live17:
Bacterial furanosides / Todd Lowary18:
1,2-Cis glycoside of amino sugar / Shino Manabe19:
Aminoglycoside antibiotics / Timor Baasov20:
Solid phase carbohydrate synthesis / Peter Seeberger ; Steffen Eller ; Markus Weishaupt21:
Novel synthesis of functional mucin glycopeptides containing both N- and O-glycans / Shin-itiro Nishimura22:
Chemoenzymatic synthesis of N-glycan / Wei Huang23:
Sialyl glycopeptides synthesis / Yosuhiro Kajihara24:
Synthesis of sialosides / Makoto Kiso25:
Metabolic glycosylation / Jennifer Kohler26:
Targeting tumors using homing peptides / Michiko Fukuda27:
Glycomics / Section I:
Mass spectrometric analysis of acidic oligosaccharides / K-H. Khoo1:
Mass Spectrometric Analysis of mutant mice / Anne Dell2:
10.

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EB
Enrique Cadenas, Lester Packer
出版情報: Elsevier ScienceDirect Books , Elsevier Science, 2010
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Contributors
Preface
Volumes in Series
Engineering of Fluorescent Reporters into Redox Domains to Monitor Electron Transfers / Derek Parsonage ; Stacy A. Reeves ; P. Andrew Karplus ; Leslie B. Poole1:
Introduction
The Problem: Low Sensitivity and Improperly Rate-Limited Assays for Redox Functions of Bacterial Peroxiredoxin Systems / 2:
The Solution: Engineering of Fluorescent Redox Reporters into the N-Terminal Domain of AhpF and E. coli Grx1 / 3:
Engineering of Disulfide-Containing Electron Acceptor Domains to Detect Electron Transfers via Fluorescence Changes; Linkage of Fluorescein to Bacterial AhpC via a Reducible Disulfide Bond / 4:
Materials / 5:
Methods / 6:
Summary / 7:
References
Blot-Based Detection of Dehydroalanine-Containing Glutathione Peroxidase with the Use of Biotin-Conjugated Cysteamine / Sue Goo Rhee ; Chun-Seok Cho
Oxidative Inactivation of Glutathione Peroxidase and the Conversion of Its Active Site Sec to DHA
Preparation of Biotin-Conjugated Cysteamine
Blot-Based Detection of DHA-GPx1 in RBCs
Effects of Oxidative Stress on the Formation of DHA-GPx1 in RBCs
Concluding Remarks
Acknowledgment
Analysis of the Redox Regulation of Protein Tyrosine Phosphatase Superfamily Members Utilizing a Cysteinyl-Labeling Assay / Benoit Boivin ; Nicholas K. Tonks
Active-Site Structure, Catalysis, and Oxidation
Detection Methods
General Principle of the Assay
Solutions
Preparation of the Lysis Buffer
Preparation of the Hypoxic Glove Box
Preparation of Cell Lysates / 8:
Cysteinyl-Labeling Assay / 9:
Acute Stimulus-Induced Reversible Oxidation of PTPs / 10:
Perspectives / 11:
Conclusion / 12:
Measuring the Redox State of Cellular Peroxiredoxins by Immunoblotting / Andrew G. Cox ; Christine C. Winterbourn ; Mark B. Hampton
Measurement of Prx Dimerization
Measurement of Prx Hyperoxidation
Discussion
Acknowledgments
Thiol Redox Transitions by Thioredoxin and Thioredoxin-Binding Protein-2 in Cell Signaling / Eiji Yoshihara ; Zhe Chen ; Yoshiyuki Matsuo ; Hiroshi Masutani ; Junji Yodoi
Functional Regulation of Redox-Sensitive Proteins by Thiol Modification
Thiol Reduction by the Thioredoxin Redox System
Thioredoxin Superfamily
Reversible Redox and Signal Regulation by Thioredoxin and Thioredoxin-binding Protein-2 (TBP-2)
Detection of Protein Thiols in Mitochondrial Oxidative Phosphorylation Complexes and Associated Proteins / Kelly K. Andringa ; Shannon M. Bailey
Mitochondria Isolation and Protein Thiol Labeling
Application of Blue Native-PAGE for the Isolation of Oxidative Phosphorylation Protein Subunits and Other Proteins Associated with the Complexes
Detection of IBTP-Labeled Protein Thiols in Protein Complexes
Analysis and Mass Spectrometry Identification of Protein
Other Considerations
Mitochondrial Thioredoxin Reductase: Purification, Inhibitor Studies, and Role in Cell Signaling / Maria Pia Rigobello ; Alberto Bindoli
Purification of Thioredoxin Reductase from Isolated Mitochondria, Cultured Cells, and Whole Organs
Estimation of Thioredoxin Reductase Activity
Inhibitor Studies of Thioredoxin Reductase
Role in Cell Signaling
Measuring Mitochondrial Protein Thiol Redox State / Raquel Requejo ; Edward T. Chouchani ; Thomas R. Hurd ; Katja E. Menger ; Michael P. Murphy
Quantification of Mitochondrial Protein Thiols
Quantification of Glutathionylation of Mitochondrial Proteins
Assessment of S-Nitrosated Protein Thiols
Measurement of the Thioredoxin and Peroxiredoxin Redox States
Conclusions
Measurement of Extracellular (Exofacial) Versus Intracellular Protein Thiols / Jolanta Skalska ; Steven Bernstein ; Paul Brookes
Measurement of Mitochondrial Thiol Status
Measurement of Cytosolic Thiol Status
Measurement of Exofacial Thiols
Exofacial Thiol Status and Cancer
Redox Clamp Model for Study of Extracellular Thiols and Disulfides in Redox Signaling / Young-Mi Go ; Dean P. Jones
Key Concepts for Use
Principles for Experimental Design
Summary of Available Redox Clamp Studies
Perspectives and Conclusion
Redox State of Human Serum Albumin in Terms of Cysteine-34 in Health and Disease / Karl Oettl ; Gunther Marsche
Background
HPLC Analysis
Albumin Thiol State and Exercise
Influence of Supplementation
Albumin Oxidation in Disease
Albumin Thiol State During Aging
Methods for Studying Redox Cycling of Thioredoxin in Mediating Preconditioning-Induced Survival Genes and Proteins / Chuang C. Chiueh
Hormetic Mechanism: Role of Redox Cycling of Thioredoxin
Redox Functioning of Thioredoxin
Implications of Preconditioning Protection from Preclinical and Clinical Studies
Drugs Mimic Thioredoxin-Medicated Preconditioning-Induced Signaling and Protection in Cells
Methods and Materials
Oxidative Stress, Thiol Redox Signaling Methods in Epigenetics / Isaac K. Sundar ; Samuel Caito ; Hongwei Yao ; Irfan Rahman13:
Histone Acetylation by Immunoblotting
HAT Activity Assay
HDAC Activity Assay
HDACs Levels by Immunoblotting
Posttranslational Modifications of HDACs and SIRTs (Sirtuins 1-7) by Immunoprecipitation
Preparation of Whole Cell Lysate
Preparation of Cytoplasmic and Nuclear Proteins
Redox-Mediated Posttranslational Modification Assays
Chromatin Immunoprecipitation (ChIP) Assay
Characterization of Protein Targets of Mammalian Thioredoxin Reductases / Anton A. Turanov ; Dolph L. Hatfield ; Vadim N. Gladyshev14:
Preparation of TR-immobilized Affinity Resins
Identification of Targets of Mammalian TRs in Cell Lysates
Concluding Remarks and Future Perspectives
Alteration of Thioredoxin Reductase 1 Levels in Elucidating Cancer Etiology / Min-Hyuk Yoo ; Bradley A. Carlson ; Petra Tsuji ; Robert Irons15:
Materials and Methods
Results and Discussion
Conclusions and Future Perspectives
Regulation of Apoptosis Signal-Regulating Kinase 1 in Redox Signaling / Kazumi Katagiri ; Atsushi Matsuzawa ; Hidenori Ichijo16:
Overview
Comment
Protocols for the Detection of S-Glutathionylated and S-Nitrosylated Proteins In Situ / Scott W. Aesif ; Yvonne M. W. Janssen-Heininger ; Niki L. Reynaert17:
Protein S-Glutathionylation
Protein S-Nitrosylation
Synthesis, Quantification, Characterization, and Signaling Properties of Glutathionyl Conjugates of Enals / Sanjay Srivastava ; Kota V. Ramana ; Aruni Bhatnagar ; Satish K. Srivastava18:
Synthesis, Quantification, and Characterization of Reagent Glutathionyl Conjugates of HNE
Metabolism of HNE
Signaling Properties of Glutathionyl Conjugates of HNE
Thioredoxin and Redox Signaling in Vasculature-Studies Using Trx2 Endothelium-Specific Transgenic Mice / Wang Min ; Luyao (Kevin) Xu ; Huanjiao (Jenny) Zhou ; Qunhua Huang ; Haifeng Zhang ; Yun He ; Xu Zhe ; Yan Luo19:
Author Index
Subject Index
Contributors
Preface
Volumes in Series
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