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1.

電子ブック

EB
David A. Hopwood, D. A. Hopwood
出版情報: Elsevier ScienceDirect Books , 2009
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Contributors
Preface
Volumes in Series
Polyketides / Section I:
Introduction to Polyketide Biosynthesis / Kira J. Weissman1:
Introduction
Acknowledgment
References
Structural Enzymology of Polyketide Synthases / Shiou-Chuan (Sheryl) Tsai ; Brian Douglas Ames2:
Fatty Acid Synthase
Different Types of PKS and a Summary of Structural Work / 3:
Structural Enzymology of Individual Domains / 4:
Summary and Future Prospects / 5:
Acknowledgments
Fungal Type I Polyketide Synthases / Russell J. Cox ; Thomas J. Simpson
Partially Reducing PKSs: 6-MethylSalicylate Synthase
Nonreducing PKSs
Highly Reducing PKSs
NR/HR PKS Hybrid Systems: Zearalenone (ZAE1 and ZAE2)
Conclusions / 6:
Tandem Acyl Carrier Protein Domains in Polyunsaturated Fatty Acid Synthases / Hui Jiang ; Scott R. Rajski ; Ben Shen
Methods
Conclusion
Iterative Type I Polyketide Synthases for Enediyne Core Biosynthesis / Geoffrey P. Horsman ; Steven G. Van Lanen
The DEBS Paradigm for Type I Modular Polyketide Synthases and Beyond / Leonard Katz
DEBS and the Concept of a Module
Beyond the DEBS Paradigm
Formation and Characterization of Acyl Carrier Protein-Linked Polyketide Synthase Extender Units / Yolande A. Chan ; Michael G. Thomas7:
Overproduction and Purification of Recombinant Proteins
Formation and Characterization of Hydroxymalonyl-ACP and Aminomalonyl-ACP
Type I Polyketide Synthases That Require Discrete Acyltransferases / Yi-Qiang Cheng ; Jane M. Coughlin ; Si-Kyu Lim8:
The Enzymology of Polyether Biosynthesis / Tiangang Liu ; David E. Cane ; Zixin Deng9:
Genetic Mining and Functional Analysis of Genes Specific to Polyether Biosynthetic Pathways
Premonensin, the Parent Unsaturated Monensin Polyketide
Epoxidases MonCl, NigCl, and NanO
Epoxide Hydrolases MonBI/BII, NigBI/BII, NanI, and Lsd19
NanE, a Polyether-Specific Thioesterase
Assay of Polyether Thioesterase Activity
Transcriptional Analysis of the Nanchangmycin Biosynthetic Pathway Genes
Enzymology of the Polyenes Pimaricin and Candicidin Biosynthesis / Juan F. Martin ; Jesus F. Aparicio10:
Pimaricin as a Prototype of Small Polyenes: Discovery and Properties
Pimaricin Biosynthesis in S. natalensis
Regulation of Pimaricin Biosynthesis
Candicidin: A Prototype of "Aromatic" Polyenes
The Candicidin/FR-008 Gene Cluster
Biosynthesis of PABA: The pabAB and pabC Genes
The Polyketide Synthases
Monooxygenase Genes: Modifications of the Polyketide Chain
Transporter Genes
Genes Related to Mycosamine Biosynthesis / 11:
Regulatory Genes / 12:
Phosphate Represses Expression of the pabAB Gene / 13:
Future Perspectives / 14:
Genetic Analysis of Nystatin and Amphotericin Biosynthesis / Sergey Zotchev ; Patrick Caffrey
Gene Inactivation and Replacement in the Nystatin Producer Streptomyces noursei
Gene Inactivation and Replacement in the Amphotericin Producer Streptomyces nodosus
Production, Purification, and Characterization of Novel Amphotericin- and Nystatin-Related Polyenes
Polyketide Versatility in the Biosynthesis of Complex Mycobacterial Cell Wall Lipids / Tarun Chopra ; Rajesh S. Gokhale
Acetate and Propionate Feeding Studies
Genome Sequencing and Identification of Polyketide Synthases
Mycobacterial Polyketide Synthases
Techniques to Characterize PKS Enzymes
Genetic Engineering to Produce Polyketide Analogues / Christopher D. Reeves ; Eduardo Rodriguez
AT Domain Replacement to Alter a-Carbon Substitution
Procedure for Engineering AT Replacements in the Chromosome
Engineering b-Carbon Processing
Engineering when only a Single Crossover Event is Possible
Heterologous Expression of Engineered PKS Genes
Chemobiosynthesis
Mutasynthesis
Gene Knockouts to Obtain Analogues
Design and Synthesis of Pathway Genes for Polyketide Biosynthesis / Salvador Peiru ; Hugo Gramajo ; Hugo G. Menzella
Redesign of PKS Genes to Accommodate Unique Restriction Sites Flanking Individual Components and for Efficient Expression in E. coli
Validation of Synthetic PKS Gene Design
A Rapid Assay to Identify Productive Combinations of PKS Modules
Assembly of Larger Polyketide Synthases Using Information Gained with the Bimodular Assay
Design and Construction of Synthetic Operons for the Expression of Sugar Pathway Genes
Heterologous Production of Polyketides in Bacteria / 15:
General Considerations for the Heterologous Expression of Polyketide Pathways
S. coelicolor as a Model System for Heterologous Expression of Polyketides
Procedure for the Heterologous Production of Polyketides in S. coelicolor
System Improvements for the Heterologous Production of Polyketides in Streptomyces spp
Recent Developments for the Production of Polyketides in Nonactinomycete Bacteria
In Vitro Analysis of Type II Polyketide Synthase / Wenjun Zhang ; Yi Tang16:
Expression and Purification of Type II PKSs
In Vitro Activity Assays
Bacterial Fatty Acid Synthesis and its Relationships with Polyketide Synthetic Pathways / John E. Cronan ; Jacob Thomas17:
Bacterial Fatty Acids
Acyl Carrier Protein, the Key Component of Bacterial Fatty Acid Synthesis
Overview of the Reactions of Fatty Acid Biosynthesis
The Initiation Steps of Fatty Acid Synthesis
The Enzymes of the Fatty Acid Elongation Cycle
Unsaturated Fatty Acid Synthesis in E. coli
The Abundant Exceptions to the E. coli Fatty Acid Synthesis Paradigm
Relationships between Fatty Acid Synthesis and Polyketide Synthesis
Methods for Study of Bacterial Fatty Acid Synthesis
Aminocoumarins / Section II:
Aminocoumarins: Mutasynthesis, Chemoenzymatic Synthesis, and Metabolic Engineering / Lutz Heide18:
Generation of Integrative Cosmids and Heterologous Expression of Novobiocin, Clorobiocin, and Coumermycin A1 Gene Clusters
Generation of Single and or Multiple Deletions in the Integrative Cosmids
Mutasynthetic Generation of New Aminocoumarin Antibiotics
In Vitro Amide Synthetase Assays for the Identification of Suitable Ring A Analogues for Mutasynthesis
Use of Various Amide Synthetase Genes for Expanding Mutasynthesis Product Range
Generation of Substrates for Chemoenzymatic Synthesis
Chemoenzymatic Synthesis of New Clorobiocin Analogues
Generation of New Aminocoumarin Antibiotics by Metabolic Engineering
Carbohydrates / Section III:
Enzymology of Aminoglycoside Biosynthesis-Deduction from Gene Clusters / Udo F. Wehmeier ; Wolfgang Piepersberg19:
Some Key Enzymes in the Biosyntheses of Aminoglycoside Antibiotics
Acarbose and Related Metabolites
Biosynthetic Enzymes for the Aminoglycosides Butirosin and Neomycin / Fumitaka Kudo ; Tadashi Eguchi20:
General Method to Investigate Functions of the Biosynthetic Enzymes for Aminoglycosides
Neamine Biosynthetic Enzymes (Enzymes 1
Contributors
Preface
Volumes in Series
2.

電子ブック

EB
William S. Allison, Anne Neville Murphy, Immo E. Scheffler
出版情報: Elsevier ScienceDirect Books , 2009
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Electron Transport Complexes / Part A:
Visualizing functional flexibility by three dimensional electron microscopy: reconstructing Complex I of the mitochondrial respiratory chain / M. Radermacher1:
Electron tomography of the mitochondrion / T. Frey ; G. Perkins ; M. Sun2:
Mid-IR vibrational studies of complex I / D. Marshall ; P. Rich3:
Electron transfer in respiratory complexes resolved by an ultra-fast freeze-quench approach / N. Belevich ; M. Verkhovsky4:
Use of ruthenium photooxidation techniques to study electron transfer in the cytochrome bc1 complex / F. Millett ; B. Durham ; C. Yu ; L. Yu5:
Use of ruthenium photoreduction techniques to study electron transfer in cytochrome oxidase / R. Gennis6:
Mass spectrometric characterization of subunits of electron transfer complexes that are encoded in the mitochondrial genome / J. Carroll ; J. Walker7:
The assembly of respiratory chain complexes studied by GFP-tagged subunits, L. Nijtmans / 8:
Two-dimensional native electrophoresis for functional assays of mitochondrial complexes / W. Wittig ; H. Schägger9:
Reliable assay for complex I in human blood lymphocytes and skin fibroblasts / L. Elly ; A. de Wit ; W. Sluiter10:
Purification of the cytochrome c reductase/cytochrome c oxidase supercomplex of yeast mitochondria / E. Boekema ; H. Braun11:
Supercomplex organization of the yeast mitochondrial respiratory chain complexes and the ADP/ATP carrier proteins / R. Stuart12:
Role of cysteine desulfurase Nfs1 in human mitochondrial Fe-S protein biogenesis / O. Stehling ; R. Lill13:
Identification and properties of the novel 2Fe-2S center in the outer membrane protein, mitoNEET / S. Wiley ; M. Rardin ; J. Dixon14:
Nucleotide-dependent iron-sulfur cluster biogenesis in mitochondria / D. Pain15:
Preparation of samples for EPR and Mössbauer spectroscopy of intact Saccharomyces cerrevisiae mitochondria / J. Garber-Morales ; R. Miao ; G. Holmes-Hampton ; P. Lindahl16:
Fluorescence correlation spectroscopy to probe mitochondrial mobility and intramatrix protein diffusion / P. Willems ; W. Koopman17:
Characterization of alternative complex I of Plasmodium falciparum mitochondria / N. Fisher ; A. J. Warman ; S. Ward ; G. Biagini18:
Analysis of respiratory chain complex assembly using radiolabeled nuclear- and mitochondrial-encoded subunits / M. McKenzie ; M. Lazarou ; M. Ryan19:
Reactive Oxygen Species / Part B:
Measuring redox changes to mitochondrial protein thiols using Redox DIGE / T. Hurd ; K. Lilley ; M. Murphy20:
Measuring the effects of Hepatitis C proteins on mitochondrial electron transport and production of reactive oxygen species / S. Weinman21:
Paraquat induced production of reactive oxygen species in brain mitochondria / D. Drechsel ; M. Patel22:
The uptake and interactions of the redox cycler paraquat with mitochondria / H. Cocheme23:
Superoxide production by rat brain and skeletal muscle mitochondria / W. Kunz24:
Quantitation, localization, and tissue specificities of mitochondrial reactive oxygen species production / C. Mathews25:
The reaction mechanisms of electron transfer and superoxide generation in the cytochrome nc1 complex / D. Xia ; S. Yang ; Y. Yin26:
Measurement of superoxide formation by mitochondrial complex I of Yarrowia lipolytica / S. Dröse ; A. Galkin ; U. Brandt27:
An improved method for introducing point mutations into the mitochondrial cytochrme b gene to facilitate studying the role of cytochrome b in the formation of reactive oxygen species / B. Trumpower28:
Electron Transport Complexes / Part A:
Visualizing functional flexibility by three dimensional electron microscopy: reconstructing Complex I of the mitochondrial respiratory chain / M. Radermacher1:
Electron tomography of the mitochondrion / T. Frey ; G. Perkins ; M. Sun2:
3.

電子ブック

EB
John N. Abelson, Tom W. Muir
出版情報: Elsevier ScienceDirect Books , 2009
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(Tentative)
Protein Engineering with the Traceless Staudinger Ligation / Ronald T. Raines ; Annie Tam1:
Mechanistic studies of RNR using unnatural amino acids and semisynthesis / Joann Stubbe2:
Using Expressed Protein Ligation to Probe the Substrate Specificity of Lantibiotic Synthetases / Wilfred van der Donk ; Xingang Zhang3:
Protein Phosphorylation by Semisynthesis: From Paper to Practice / Phlip A. Cole,Lawrence M. Szewczuk ; Mary Katherine Tarrant4:
Mechanistic studies of semisynthetic ion channels / Francis Valiyaveetil5:
Semi-synthesis of proteins using split inteins / Henning D. Mootz ; Christina Ludwig ; Joachim Zettler ; Daniel Garbe6:
Segmental Isotopic Labeling of Proteins for Nuclear Magnetic Resonance / David Cowburn ; Dongsheng Liu ; Rong Xu7:
Use of intein-mediated protein ligation strategies for the fabrication of functional protein arrays / Shao Q Yao ; Souvik Chattopadhaya ; Farhana B. Abu Bakar8:
Expressed Protein Ligation for Metalloprotein Design and Engineering / Yi Lu ; Kenneth Clark9:
(Tentative)
Protein Engineering with the Traceless Staudinger Ligation / Ronald T. Raines ; Annie Tam1:
Mechanistic studies of RNR using unnatural amino acids and semisynthesis / Joann Stubbe2:
4.

電子ブック

EB
Daniel Herschlag
出版情報: Elsevier ScienceDirect Books , Elsevier Science & Technology, 2009
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Contributors
Preface
Volumes in Series
Chemical and Functional Probing of RNA Structure, Interactions, and Folding / Section I:
Nucleotide Analog Interference Mapping / Ian T. Suydam ; Scott A. Strobel1:
Introduction
Materials and Reagents / 2:
Methods / 3:
Properties of Analogs / 4:
Nucleotide Analog Interference Suppression / 5:
Conclusions / 6:
References
Hydroxyl-Radical Footprinting to Probe Equilibrium Changes in RNA Tertiary Structure / Inna Shcherbakova ; Somdeb Mitra
Sample Preparation
Equilibrium òOH Footprinting Based on Peroxidative Fenton Chemistry
Equilibrium òOH Footprinting Based on Oxidative Fenton Chemistry
Cleavage Product Separation
Quantitation of the Changes in the Reactivity and Data Analysis
Acknowledgments / 7:
Rapid Quantification and Analysis of Kinetic òOH Radical Footprinting Data Using SAFA / Katrina Simmons ; Joshua S. Martin ; Alain Laederach
Using SAFA
Data Normalization
Data Visualization
Conclusion
Acknowledgment
High-Throughput SHAPE and Hydroxyl Radical Analysis of RNA Structure and Ribonucleoprotein Assembly / Jennifer L. McGinnis ; Caia D. S. Duncan ; Kevin M. Weeks
Theory
Practice
Examples and Interpretation
Perspectives and Conclusion
Metal Ion-Based RNA Cleavage as a Structural Probe / Marcello Forconi ; Daniel Herschlag
Mechanisms of Metal Ion-Based Cleavage of Nucleic Acids
Metal Ion-Based Cleavage of RNA as a Structural Probe
Protocols
2'-Amino-Modified Ribonucleotides as Probes for Local Interactions Within RNA / James L. Hougland ; Joseph A. Piccirilli
2'-Amino-2'-Deoxynucleotide Synthesis and Incorporation
2'-Amino-2'-Deoxynucleotides as Sites for Covalent Modification
General Strategy for Investigating 2'-Hydroxyl Interactions Using 2'-Deoxy and 2'-Aminonucleotides
Studies of RNA Catalysis Using 2'-Amino-2'-Deoxynucleotides
Using 2'-Aminonucleotides to Investigate RNA Structure and Function: Case Studies
RNA Crosslinking Methods / Michael E. Harris ; Eric L Christian
Synthesis of Modified RNA Crosslinking Substrates
Generation of Crosslinked RNAs
Mapping of Crosslinked Nucleotides
Assessing the Validity of Crosslinking Data
Chemical Probing of RNA and RNA/Protein Complexes / Zhili Xu ; Gloria M. Culver8:
Materials
Handling of the Chemicals
Optimization of the Chemical Probing Reactions
Procedure of Chemical Probing
RNA Extraction
Normalization of the RNA Sample
Primer Extension Analysis
Data Evaluation / 9:
Summary / 10:
RNA Folding During Transcription: Protocols and Studies / Terrence N. Wong ; Tao Pan
Protocol 1: Determination of Transcriptional Pause Sites
Protocol 2: Structural Mapping of Paused Complexes
Protocol 3: Cotranscriptional RNA Folding as Measured via Oligohybridization
Protocol 4: Cotranscriptional RNA Folding Measured via P RNA Catalytic Activity
Protocol 5: The Folding of Self-Cleaving RNAs During Transcription
Additional Methodologies
Cotranscriptional Folding Studies from our Laboratory
Catalytic Activity as a Probe of Native RNA Folding / Yaqi Wan ; David Mitchell III ; Rick Russell
Preliminary Measurements of Catalytic Reaction
Following RNA Folding by Continuous Activity Assay
Following RNA Folding by Discontinuous Activity Assay
Other Applications of Catalytic Activity as a Probe of Folding
Probing RNA Structure Within Living Cells / Andreas Liebeg ; Christina Waldsich11:
Experimental Procedure
Application
Limitations
Structural Analysis of RNA in Living Cells by In Vivo Synchrotron X-Ray Footprinting / Tadepalli Adilakshmi ; Sarah F. C. Soper ; Sarah A. Woodson12:
Beamline Setup for In Vivo Footprinting
Preparation of Samples
Exposure of Cells to X-Ray Beam
Isolation of Total RNA from Irradiated Cells
Primer Extension
Analysis of X-Ray Footprinting Experiments
Results on E. coli RNAs
Future of Footprinting
Determination of Intracellular RNA Folding Rates Using Self-Cleaving RNAs / Peter Y. Watson ; Martha J. Fedor13:
Using RNA Turnover Rates as a "Clock" for Measuring RNA Assembly Kinetics
Applications
Identifying Metal Ion Interactions in RNA / Section II:
Separation of RNA Phosphorothioate Oligonucleotides by HPLC / John K. Frederiksen14:
Introduction: Phosphorothioate Oligonucleotides and the Need for Separation
HPLC Separation of Phosphorothioate Diastereomers
Materials and Methods
Examples of Phosphorothioate Oligonucleotide Separations
Use of Phosphorothioates to Identify Sites of Metal-Ion Binding in RNA / 15:
Use of Phosphorothioate-Containing Ribozymes to Identify Sites of Metal-Ion Binding
EPR Methods to Study Specific Metal-Ion Binding Sites in RNA / Laura Hunsicker-Wang ; Matthew Vogt ; Victoria J. DeRose16:
ENDOR Spectroscopy to Identify Metal Ligands
ESEEM Spectroscopy
RNA Thermodynamics / Section III:
Optical Melting Measurements of Nucleic Acid Thermodynamics / Susan J. Schroeder ; Douglas H. Turner17:
Instrumentation
Calibrations
Brief Theory of Optical Melting Experiments
Two-State Assumption
Experimental Design
Data Interpretation
Error Analysis
Analyzing RNA and DNA Folding Using Temperature Gradient Gel Electrophoresis (TGGE) with Application to In Vitro Selections / Durga M. Chadalavada ; Philip C. Bevilacqua18:
Temperature Gradient Gel Electrophoresis
Experimental Design and Application of TGGE to RNA and DNA
Studying RNA-DNA and RNA-Protein Interactions by Isothermal Titration Calorimetry / Andrew L. Feig19:
Required Materials
Sample Considerations and Preparation
Cleaning the Sample Cell and Titration Syringe
Collecting Titration Data
Data Processing and Analysis
Special Considerations
Author Index
Subject Index
Contributors
Preface
Volumes in Series
5.

電子ブック

EB
Richard R Burgess, Richard Burgess, Murray P. Deutscher
出版情報: Elsevier ScienceDirect Books , Elsevier Science, 2009
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Why Purify Enzymes? / Murray Deutscher ; Arthur Kornberg
Developing Purification Procedures / Section I:
Strategies and Considerations for Protein Purifications / Stuart Linn
Use of Bioinformatics in Planning a Protein Purification / Richard R. Burgess
Preparing A Purification Summary Table
General Methods for Handling Proteins and Enzymes / Section II:
Setting Up A Laboratory / Murray P. Deutscher
Buffers: Principle and Practice / Vincent S. Stoll ; John S. Blanchard
Measurement of Enzyme Activity / T. K. Harris ; M. M. Keshwani
Quantitation of Protein / James E. Noble ; Marc J. A. Bailey
Concentration of Proteins and Removal of Solutes / Jonathan K. Romero ; David R. H. Evans ; Matthew Westoby
Maintaining Protein Stability
Recombinant Protein Expression and Purification / Section III:
Selecting an Appropriate Method for Expressing a Recombinant Protein / William H. Brondyk
Bacterial Systems for Production of Heterologous Proteins / Frank R. Collart ; Ashley M. Frank ; Sarah Zerbs
Expression in the Yeast Pichia Pastoris / James M. Cregg ; Ilya Tolstorukov ; Anasua Kusari ; Jay Sunga ; Knut Madden ; Thomas Chappell
Baculovirus-Insect Cell Expression Systems / Donald L. Jarvis
Recombinant Protein Production By Transient Gene Transfer Into Mammalian Cells / Sabine Geisse ; Cornelia Fux
Tagging For Protein Expression / Arun Malhotra
Refolding of Solubilized Inclusion Body Proteins
Preparation of Extracts and Subcellular Fractionation / Section IV:
Advances In Preparation of Biological Extracts for Protein Purification / Anthony C. Grabski
Isolation of Subcellular Organelles and Structures / Jörg Von Hagen ; Uwe Michelsen
Purification Procedures: Bulk Methods / Section V:
Protein Precipitation Techniques
Affi-Gel Blue for Nucleic Acid Removal and Early Enrichment of Nucleotide Binding Proteins
Purification Procedures: Chromatographic Methods / Section VI:
Ion Exchange Chromatography / Alois Jungbauer ; Rainer Hahn
Gel Filtration / Earle Stellwagen
Protein Chromatography on Hydroxyapatite Columns / Larry J. Cummings ; Mark A. Snyder ; Kimberly Brisack
Theory and Use of Hydrophobic Interaction Chromatography in Protein Purification Applications / Justin T. Mccue
Purification Procedures: Affininty Methods / Section VII:
Affinity Chromatography: General Methods / Marjeta Urh ; Dan Simpson ; Kate Zhao
Immobilized-Metal Affinity Chromatography (IMAC) / Frank Schäfer* Helena Block ; Barbara Maertens ; Anne Spriestersbach ; Nicole Brinker ; Jan Kubicek ; Roland Fabis And Jörg Labahn
Identification, Production, and Use of Polyol-Responsive Monoclonal Antibodies for Immunoaffinity Chromatography / Nancy E. Thompson ; Katherine M. Foley ; Elizabeth S. Stalder ; And Richard R. Burgess
Purification Procedures: Electrophoretic Methods / Section VIII:
One-Dimensional Gel Electrophoresis / David E. Garfin
Protein Analysis Using High-Resolution Two-Dimensional Polyacrylamide Gel Electrophoresis and Isoelectric Focusing / Friedman
Protein Gel Staining Methods: An Introduction And Overview / Thomas H. Steinberg
Elution of Proteins From Gels
Immunodetection By Protein Blotting Performing and Optimizing Western Blots With An Emphasis on Chemiluminescent Detection / Alice Alegria-Schaffer ; Krishna Vattem ; Andrew Lodge
Purification Procedures: Membrane Proteins And Glycoproteins / Section IX:
Detergents: An Overview / Dirk Linke
Purification of Membrane Proteins / Sue-Hwa Lin ; Guido Guidotti
Purification of Recombinant G-Protein-Coupled Receptors / Reinhard Grisshammer
Cell-Free Translation Of Integral Membrane Proteins Into Unilamelar Liposomes / Michael A. Goren ; Akira Nozawa ; Shin-Ichi Makino ; Russell L. Wrobel ; Brian G. Fox
Characterization of Purified Proteins / Section X:
Determination of Protein Purity / David G. Rhodes ; Thomas M. Laue
Determination of Size, Molecular Weight, and Presence of Subunits / Robert E. Bossio
Identification and Quantification of Protein Posttranslational Modifications / Andrew Link
Parallel Methods For Expression And Purification / Scott A. Lesley
Techniques To Isolate O2-Sensitive Proteins: [4Fe-4S]-FNR As An Example / Aixin Yan ; Patricia J. Kiley
Rethinking Your Purification Procedure
Important But Little Known (Or Forgotten) Artifacts in Protein Biochemistry
Why Purify Enzymes? / Murray Deutscher ; Arthur Kornberg
Developing Purification Procedures / Section I:
Strategies and Considerations for Protein Purifications / Stuart Linn
6.

電子ブック

EB
Daniel J. Klionsky
出版情報: Elsevier ScienceDirect Books , 2009
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LC3-based assay for monitoring autophagy / Shunsuke Kimura ; Naonobu Fujita ; Takeshi Noda ; Tamotsu YoshimoriChapter 1:
Analysis of autophagy using GFP-LC3 transgenic mice / Noboru MizushimaChapter 2:
Photoactivatable GFP / Jennifer Lippincott-Schwartz ; Dale HaileyChapter 3:
Assaying for autophagic protein degradation / Fred MeijerChapter 4:
Sequestration assays for mammalian autophagy / Per O. SeglenChapter 5:
Incorporation of monodansylcadaverine (MDC) as an assay to assess autophagy induction and monitoring fusion with a degradative compartment / Maria Isabel ColomboChapter 6:
The GST-BHMT assay and related assays for autophagy / Carol A. Mercer ; Patrick B. DennisChapter 7:
Redox and autophagy-ROS as an indicator for autophagic activity / Ruth Scherz-Shouval ; Zvulun ElazarChapter 8:
FACS analysis of autophagy / Elena Shvets ; Ephraim FassChapter 9:
Electron microscopy in mammals / PSivi YlS-Anttila ; Eeva-Liisa EskelinenChapter 10:
Monitoring mTOR activity / Ken InokiChapter 11:
Using p62 as a marker for autophagy / Terje JohansenChapter 12:
Cytosolic LC3 ratio as a quantitative index of macroautophagy / Motoni Kadowaki ; Md. Razaul KarimChapter 13:
Pexophagy in mammalian cells / Junji Ezaki ; Takashi Ueno ; Eiki Kominami ; Masaaki KomatsuChapter 14:
Mitophagy in mammalian cells / Ji Zhang ; Paul A. NeyChapter 15:
Quantification of WIPI-1/Atg18 puncta formation for assessing mammalian autophagy / Tassula Proikas-Cezanne ; Simon G. PfistererChapter 16:
Correlative light and electron microscopy (CLEM) using GFP-LC3 and other autophagosome markers / Sharon Tooze ; Minoo RaziChapter 17:
Nanotechnology assays for autophagy / Oleksandr SeleverstovChapter 18:
Photoconvertible KAEDA-LC3 for monitoring autophagic flux / Christoph Goemans ; Aviva TolkovskyChapter 19:
Methods to monitor Chaperone-mediated autophagy / Ana Maria Cuervo ; Susmita KaushikChapter 20:
Autophagy in response to Salmonella enterica serovar Typhimurium infection / Cheryl Birmingham ; John BrumellChapter 21:
Monitoring autophagy during Mycobacterium tuberculosis infection / Vojo DereticChapter 22:
Shigella, Listeria and Streptococcus induction of autophagy / Michinaga Ogawa ; Yuko Yoshikawa ; Ichiro Nakagawa ; Chihiro Sasakawa ; Trinad ChakrabortyChapter 23:
Measuring the impact of infection on autophagy in macrophages / Jean-Francois Dubuisson ; Brenda Byrne ; Michele SwansonChapter 24:
LC3-based assay for monitoring autophagy / Shunsuke Kimura ; Naonobu Fujita ; Takeshi Noda ; Tamotsu YoshimoriChapter 1:
Analysis of autophagy using GFP-LC3 transgenic mice / Noboru MizushimaChapter 2:
Photoactivatable GFP / Jennifer Lippincott-Schwartz ; Dale HaileyChapter 3:
7.

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EB
Ludwig Brand, Michael L. Johnson
出版情報: Elsevier ScienceDirect Books , 2009
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Contributors
Preface
Volumes in Series
Phase Response Curves: Elucidating the Dynamics of Coupled Oscillators / A. Granada ; R. M. Hennig ; B. Ronacher ; A. Kramer ; H. Herzel1:
Introduction
Estimation of Phase Response Curves / 2:
Specific Applications / 3:
Discussion / 4:
Acknowledgments / Appendix I:
References
Multiple Ion Binding Equilibria, Reaction Kinetics, and Thermodynamics in Dynamic Models of Biochemical Pathways / Kalyan C. Vinnakota ; Fan Wu ; Martin J. Kushmerick ; Daniel A. Beard
Biochemical Conventions and Calculations
Application to Physiological Systems
Acknowledgment
Analytical Methods for the Retrieval and Interpretation of Continuous Glucose Monitoring Data in Diabetes / Boris Kovatchev ; Marc Breton ; William Clarke
Decomposition of Sensor Errors
Measures of Average Glycemia and Deviation from Target
Risk and Variability Assessment
Measures and Plots of System Stability / 5:
Time-Series-Based Prediction of Future BG Values / 6:
Conclusions / 7:
Analysis of Heterogeneity in Molecular Weight and Shape by Analytical Ultracentrifugation Using Parallel Distributed Computing / Borries Demeler ; Emre Brookes ; Luitgard Nagel-Steger
Methodology
Job Submission
Results
Discrete Stochastic Simulation Methods for Chemically Reacting Systems / Yang Cao ; David C. Samuels
The Chemical Master Equation
The Stochastic Simulation Algorithm
The Tau-Leaping Method
Measurement of Simulation Error
Software and Two Numerical Experiments
Conclusion
Analyses for Physiological and Behavioral Rhythmicity / Harold B. Dowse
Types of Biological Data and Their Acquisition
Analysis in the Time Domain
Analysis in the Frequency Domain
Time/Frequency Analysis and the Wavelet Transform
Signal Conditioning
Strength and Regularity of a Signal
A Computational Approach for the Rational Design of Stable Proteins and Enzymes: Optimization of Surface Charge-Charge Interactions / Katrina L. Schweiker ; George I. Makhatadze8:
Computational Design of Surface Charge-Charge Interactions
Experimental Verification of Computational Predictions
Closing Remarks
Efficient Computation of Confidence Intervals for Bayesian Model Predictions Based on Multidimensional Parameter Space / Amber D. Smith ; Alan Genz ; David M. Freiberger ; Gregory Belenky ; Hans P. A. Van Dongen
Height of the Probability Density Function at the Boundary of the Smallest Multidimensional Confidence Region
Approximating a One-Dimensional Slice of the Probability Density Function by Means of Normal Curve Spline Pieces
Locating the Boundary of the Smallest Multidimensional Confidence Region
Finding the Minimum and Maximum of the Prediction Model over the Confidence Region
An Application: Bayesian Forecasting of Cognitive Performance Impairment during Sleep Deprivation
95% Confidence Intervals for Bayesian Predictions of Cognitive Performance Impairment during Sleep Deprivation
Appendix
Analyzing Enzymatic pH Activity Profiles and Protein Titration Curves Using Structure-Based pK<a/ Calculations and Titration Curve Fitting / Jens Erik Nielsen9:
Calculating the pH Dependence of Protein Characteristics
Setting up and Running a pKa/ Calculation
Analyzing the Results of a pKa/ Calculation
How Reliable Are Calculated pKa/ Values?
Predicting pH Activity Profiles
Decomposition Analysis
Predicting Protein Stability Profiles
Fitting pH Titration Curves, pH Activity Profiles, and pH Stability Profiles
Least Squares in Calibration: Weights, Nonlinearity, and Other Nuisances / Joel Tellinghuisen10:
Review of Least Squares
Experiment Design Using Vprior/-Numerical Illustrations
Evaluation and Comparison of Computational Models / Jay I. Myung ; Yun Tang ; Mark A. Pitt11:
Conceptual Overview of Model Evaluation and Comparison
Model Comparison Methods
Model Comparison at Work: Choosing between Protein Folding Models
Desegregating Undergraduate Mathematics and Biology - Interdisciplinary Instruction with Emphasis on Ongoing Biomedical Research / Raina Robeva12:
Course Description
Mathematical Algorithms for High-Resolution DNA Melting Analysis / Robert Palais ; Carl T. Wittwer13:
Extracting Melting Curves from Raw Fluorescence
Methods Used for Clustering and Classifying Melting Curves by Genotype
Methods Used for Modeling Melting Curves
Biomathematical Modeling of Pulsatile Hormone Secretion: A Historical Perspective / William S. Evans ; Leon S. Farhy ; Michael L. Johnson14:
Early Attempts to Identify and Characterize Pulsatile Hormone Release
Impact of Sampling Protocol and Pulse Detection Algorithm on Hormone Pulse Detection
Application of Deconvolution Procedures for the Identification and Characterization of Hormone Secretory Bursts
Limitations and Subsequent Improvements in Deconvolution Procedures
Evaluation of Pulsatile and Basal Hormone Secretion Using a Stochastic Differential Equations Model
Characterization of Regulation of Signal and Response Elements: Estimation of Approximate Entropy
Evaluation of Coupled Systems
Evaluation of Hormonal Networks with Feedback Interactions
Future Directions
AutoDecon: A Robust Numerical Method for the Quantification of Pulsatile Events / Lenore Pipes ; Paula P. Veldhuis ; Ralf Nass ; Michael O. Thorner15:
Methods
Modeling Fatigue over Sleep Deprivation, Circadian Rhythm, and Caffeine with a Minimal Performance Inhibitor Model / Patrick L. Benitez ; Gary H. Kamimori ; Thomas J. Balkin ; Alexander Greene16:
Author Index
Subject Index
Contributors
Preface
Volumes in Series
8.

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David A. Hopwood, D. A. Hopwood
出版情報: Elsevier ScienceDirect Books , 2009
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Overview articles / Part 1:
Introduction - chemical classes of complex natural products and overview of their biosynthesis
Discovery of novel natural products
Trans-modification of intermediates on the assembly line in PKS, FAS and NRPS biosynthesis
Post-assembly line modifications, including glycosylation
Cloning and analysis of natural product pathways
In silico prediction of pathways from DNA sequence
Mass spectrometric analysis of PKS and NRPS biosynthetic intermediates
Synthetic probes for PKS and NRPS biochemistry
Directed evolution of natural products
Expression in a heterologous host
Pathway-specific and global regulation of antibiotic biosynthesis
Regulation of antibiotic production by bacterial hormones
Peptides / Part 2:
Non-ribosomally-synthesised peptides Overview of NRPSs, and mechanistic and structural studies / A:
Siderophores Cephamycins and clavulanic acid
Glycopeptides
Lipopeptides
Precursor
Biosynthesis
Ribosomally synthesised peptides / B:
Lantibiotic biosynthesis and engineering of novel compounds
Cyclic peptides from marine bacteria
Overview articles / Part 1:
Introduction - chemical classes of complex natural products and overview of their biosynthesis
Discovery of novel natural products
9.

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Gary K. Ackers, Jo M. Holt, Michael L. Johnson
出版情報: Elsevier ScienceDirect Books , 2009
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Contributors
Preface
Volumes in Series
Practical Approaches to Protein Folding and Assembly: Spectroscopic Strategies in Thermodynamics and Kinetics / Jad Walters ; Sara L. Milam ; A. Clay Clark1:
Introduction
Equilibrium Unfolding / 2:
Measuring Folding Kinetics / 3:
References
Using Thermodynamics to Understand Progesterone Receptor Function: Method and Theory / Keith D. Connaghan-Jones ; David L. Bain
Assessing Protein Functional and Structural Homogeneity
Dissecting Linked Assembly Reactions
Analysis and Dissection of Natural Promoters / 4:
Measuring the Energetics of Coactivator Recruitment / 5:
Correlation to Biological Function / 6:
Conclusions and Future Directions / 7:
Acknowledgments
General Principles / Dan Grilley ; Ana Maria Soto ; David E. Draper
Ion-Binding Properties of HQS
Preparation of Solutions and Reagents
Instrumentation and Data Collection Protocols
Data Analysis
Controls and Further Considerations
Analysis of Repeat-Protein Folding Using Nearest-Neighbor Statistical Mechanical Models / Tural Aksel ; Doug Barrick
Historical Overview of Ising Models and Motivation for the Present Review
Linear Repeat Proteins and Their Connection to Linear Ising Models
Formulating a Homopolymer Partition Function and the Zipper Approximation
Matrix Approach: Homopolymers
Matrix Approach: Heteropolymers
Solvability Criteria for Ising Models Applied to Repeat-Protein Folding
Matrix Homopolymer Analysis of Consensus TPR Folding
Matrix Heteropolymer Analysis of Consensus Ankyrin Repeat Folding / 8:
Summary and Future Directions / 9:
Isothermal Titration Calorimetry: General Formalism Using Binding Polynomials / Ernesto Freire ; Arne Schön ; Adrian Velazquez-Campoy
The Binding Polynomial
Microscopic Constants and Cooperativity
Independent or Cooperative Binding?
Analysis of ITC Data Using Binding Polynomials
A Typical Case: Macromolecule with Two Ligand-Binding Sites
Data Interpretation
An Experimental Example
Experimental Situations from the Literature / 10:
Macromolecule with Three Ligand-Binding Sites / 11:
Conclusions / 12:
Appendix
Acknowledgment
Kinetic and Equilibrium Analysis of the Myosin ATPase / Enrique M. De La Cruz ; E. Michael Ostap
Reagents and Equipment Used for all Assays
Steady-State ATPase Activity of Myosin
Steady-State Measurement of Actomyosin Binding Affinities
Transient Kinetic Analysis of the Individuals ATPase Cycle Transitions
Kinetic Simulations
The Hill Coefficient: Inadequate Resolution of Cooperativity in Human Hemoglobin / Jo M. Holt ; Gary K. Ackers
Cooperativity and Intrinsic Binding
The Macroscopic Binding Isotherm
The Hill Coefficient
Microscopic Cooperativity in Hemoglobin
Summary
Methods for Measuring the Thermodynamic Stability of Membrane Proteins / Heedeok Hong ; Nathan H. Joh ; James U. Bowie ; Lukas K. Tamm
Two Classes of Membrane Proteins
Methods for Measuring Transmembrane Domain Oligomer Stability
Methods for Measuring Multipass ?-helical Membrane Protein Stability
Methods to Study the Stability of ?-barrel Membrane Proteins
A Few Salient Results on Forces that Stabilize Membrane Proteins
Conclusion and Outlook
NMR Analysis of Dynein Light Chain Dimerization and Interactions With Diverse Ligands / Gregory Benison ; Elisar Barbar
NMR Methodology
Monomer-dimer Equilibrium Coupled to Electrostatics
Dimerization is Coupled to Ligand Binding
Folding is Coupled to Binding
Allostery in LC8
Characterization of Parvalbumin and Polcalcin Divalent Ion Binding by Isothermal Titration Calorimetry / Michael T. Henzl
Practical Aspects of Data Collection
Illustrative Global ITC Analyses of Divalent Ion Binding
Conclusion
Energetic Profiling of Protein Folds / Jason Vertrees ; James O. Wrabl ; Vincent J. Hilser
Modeling the Native State Ensemble of Proteins using Statistical Thermodynamics
Energetic Profiles of Proteins Derived from Thermodynamics of the Native State Ensemble
Principal Components Analysis of Energetic Profile Space
Energetic Profiles are Conserved Between Homologous Proteins
Direct Alignment of Energetic Profiles Based on a Variant of the CE Algorithm
CE Algorithm Described for Structure Coordinates
Necessary Deviations from the CE Algorithm to Accommodate Energetic Profiles
Towards a Thermodynamic Homology of Fold Space: Clustering Energetic Profiles using STEPH
Energetic Profiles Provide a Vehicle to Discover Conserved Substructures in the Absence of Known Homology
Model Membrane Thermodynamics and Lateral Distribution of Cholesterol: From Experimental Data To Monte Carlo Simulation / Juyang Huang
Materials and Methods
Result and Discussion
Concluding Remarks
Thinking Inside the Box: Designing, Implementing, and Interpreting Thermodynamic Cycles to Dissect Cooperativity in RNA and DNA Folding / Nathan A. Siegfried ; Philip C. Bevilacqua13:
Folding Cooperativity Defined
Thermodynamic Boxes: Design, Implementation, and Interpretation
Thermodynamic Cubes: Design, Implementation, and Interpretation
Examples of Cooperativity in RNA
Measuring Thermodynamic Parameters by UV Melting
The Thermodynamics of Virus Capsid Assembly / Sarah Katen ; Adam Zlotnick14:
The Structural Basis of Capsid Stability
Analysis of Capsid Stability
Applications of Thermodynamic Evaluation of Virus Capsid Stability
Extracting Equilibrium Constants from Kinetically Limited Reacting Systems / John J. Correia ; Walter F. Stafford15:
Methods
Simulation and Analysis of Dimerization
Kinetically Mediated Dimerization
A Stepwise Approach
Final Thoughts
Author Index
Subject Index
Contributors
Preface
Volumes in Series
10.

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William S. Allison, Anne Neville Murphy, Immo E. Scheffler
出版情報: Elsevier ScienceDirect Books , 2009
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Defining the Mitochondrial Proteome
Method to define the mammalian mitochondrial proteome / V. Mootha1:
Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry / X.Fang ; C. S. Lee2:
Method to analyze tissue heterogeneity of the mammalian mitochondrial proteome / R. S. Balaban3:
Predicting proteomes of mitochondria and related organelles from genomic and expressed sequence tag data / D. Gaston, A. Tsausis ; A. Roger4:
MitoP2: the mitochondrial proteome database / H. Prokisch Post-Translational Modifications of Mitochondrial Proteins5:
Reversible protein acetylation in mitochondria / E. Verdin6:
Post-translational modifications of rat liver mitochondria outer membrane proteins' / C. L. Hoppel7:
Characterization of a novel ser/thr protein phosphatase in mitochondria / Y. Wang8:
Selective enrichment in phosphopeptides for the identification of phosphorylated mitochondrial proteins / R. Rizzuto ; G. Pocsfalvi9:
Isolation of Regulatory-competent, Phosphorylated Cytochrome c and Cytochrome c Oxidase / M. Hnttemann11:
Identification of tyrosine phosphorylated proteins by Src kinases in rat brain / M. Salvi12:
Detection of a mitochondrial kinase complex that mediates an ERK-dependent phosphorylation of mitochondrial protein in steroid biosynthesis / E. J. Podestß13:
Dual specific phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane / J. Rardin ; J. E. Dixon14:
"Isolation and identification of palmitoylated proteins in mitochondria using a chemical biology approach L. G. Berthiaume Mitochondrial Dynamics / M. A. Kostiuk ; B. O. Keller15:
Mitochondrial fusion and movement using photoactivatable GFP / O. Shirihai16:
Regulation of mitochondrial fission and fusion by kinase and phosphatase activities. no title yet / S. Strack17:
Mitochondrial movement and synaptic function in Drosophila / T. L. Schwarz18:
The use of yeast and a novel biosensor to study mitochondrial ion transport, swelling, and mitophagy / R. J. Scheweyen19:
Complete Exchange of mtDNA's between Mouse Cells for Testing the Effects of mtDNA on Tumor Phenotypes / J. Hayashi Mitochondrial Function in Pancreatic Beta Cells20:
Coupling efficiency INS-1E cells / M. D. Brand ; C. Affourtit21:
Methods in the study of substrate-specific differences on mitochondrial function mediating insulin secretion from pancreatic beta cells / B. E. Corkey22:
Knocking down of UCP 2 in animal models of obesity / L. A.Velloso23:
Roles of the cytosolic and mitochondrial forms of the malic enzyme on insulin secretion / G. W. Cline24:
Altered regulation of the PINK1 locus as a link between type 2 diabetes and neurodegeneration / J. A. Timmons25:
Insulin secretion from pancreatic beta cells is affected deletion of the nicotinamide nucleotide transhydrogenase / R. D. Cox26:
Determination of oxidative capacity and mitochondrial function in insulin resistance and type 2 diabetes / G. Shulman et al27:
Mitochondrial ATP production rate / K. S. Nair28:
Defining the Mitochondrial Proteome
Method to define the mammalian mitochondrial proteome / V. Mootha1:
Proteome Characterization of Mouse Brain Mitochondria Using Electrospray Ionization Tandem Mass Spectrometry / X.Fang ; C. S. Lee2:
11.

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EB
Gary K. Ackers, Jo M. Holt, Michael L. Johnson
出版情報: Elsevier ScienceDirect Books , Elsevier Science & Technology, 2009
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NMR-based approaches for assessing effects of macromolecular crowding on globular proteins / Gary Pielak ; Andrew Miklos ; Lisa Charlton ; Conggang Li1:
Fluorescence spectroscopy in thermodynamic and kinetic analysis of membrane protein insertion / Alexey S. Ladokhin2:
Evaluating the energy-dependent "binding" in the early stage of protein import into chloroplasts / Mitsuru Akita ; Hitoshi Inoue3:
DNA length-dependent periodic properties of cooperative protein-DNA complexes / Michael Fried4:
Applying thermodynamic linkage to the study of pyruvate kinase / Aron Fenton5:
Conformational Stability of Cytochrome C / Reinhard Schweitzer-Stenner6:
Metadynamics methods applied to ion channel gating / Carmen Domene7:
Measuring Co-translational Conformations of Nascent Polypeptide Chains / Patricia L. Clark ; Krastyu G. Ugrinov8:
Taking an energetic approach to assess and explain cooperative gating phenomena in voltage-dependent potassium channels / Yifrach Ofer ; Zandany Nitzan ; Tzilhav Shem-Ad9:
Energetics of the collagen triple helix / Yujia Xu10:
Use of pressure perturbation calorimetry to characterize the volumetric properties of proteins / Katrina L. Schweiker ; George Makhatadze11:
Thermodynamic approaches to nucleosome-histone interactions / Andrew Andrews ; Karolin Luger12:
Thermodynamic approaches to carbohydrate binding by the agrin-G3 domain / Andrei T. Alexandrescu13:
Energetic methods applied to allostery in thrombin / Enrico Di Cera14:
Thermodynamics of protein translocation / Arnold J.M Driessen ; Alexej Kedrov15:
Solvent denaturation of proteins and the interpretation of the m-value / J. Martin Scholtz ; Nick Pace16:
Energetic approaches to the characterization of the E. coli PriA helicase / Wlodek Bujalowski17:
Protein-protein interactions and macromolecular stability / Lisa Gloss18:
Methods for assessing T cell receptor recognition / Brian M Baker19:
Thermodynamic analysis applied to bromodomain-histone interactions / Martin Thompson20:
Thermodynamic parameters fo dimer-dimer interaction in 2-cys peroxiredoxin / Karl-Josef Dietz21:
Small molecule-membrane interactions / Anne Hinderliter22:
Constant pH molecular dynamics simulations / Jana Khandogin Shen23:
NMR-based approaches for assessing effects of macromolecular crowding on globular proteins / Gary Pielak ; Andrew Miklos ; Lisa Charlton ; Conggang Li1:
Fluorescence spectroscopy in thermodynamic and kinetic analysis of membrane protein insertion / Alexey S. Ladokhin2:
Evaluating the energy-dependent "binding" in the early stage of protein import into chloroplasts / Mitsuru Akita ; Hitoshi Inoue3:
12.

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EB
Damon J. Hamel, Tracy M. Handel
出版情報: Elsevier ScienceDirect Books , 2009
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Structure and Function
A Novel Chemokine-mediated In Vivo T Cell Recruitment Assay for Structure Function Studies / Andrew D. Luster ; Gabriele Campanella1:
Tyrosine sulfation of HIV-1 coreceptors and other chemokine-binding receptors / Micheal R. Farzan2:
Lymphotactin Structural Dynamics / Brian F. Volkman3:
Regulation of chemokines by posttranslational modifications / Paul Proost4:
Proteolytic Processing of Chemokines: Mass Spectrometry, Biochemistry, Neoepitope Antibody and Functional Characterization / Christopher Overall ; Amanda Starr5:
Multiple approaches to study Chemokine Receptor Homo and Heterodimerization / Mario Mellado6:
Heterodimerization of Chemokine Receptors with Other GPCRs / Graeme Milligan ; Shirley Appelbe7:
Homo and Hetero-Oligomerization of Chemokines / Tracy Handel ; Damon Hamel ; Ariane Jansma8:
Interactions of Chemokine with Glycosaminoglycans / Amanda Proudfoot9:
Structures of Chemokine:Chemokine Binding Protein Complexes / Andreas J. Kungl ; Daved Fremont10:
Activation Mechanisms of Chemokine Receptors / Mette Rosenkilde12:
Modeling Small Molecule Compound Binding to Receptors / Richard Horuk ; James Pease ; N. Vaidehi13:
Spectroscopic Approaches to Study Conformational Changes in GPCRs / David Farrens14:
Plasmon Resonance Methods in GPCR Signaling / Victor Hruby ; Isabel Alves ; Gordon Tollin15:
Flow Cytometric Analyses of GPCR Interactions or Rapid-mix flow cytometry measurements of subsecond regulation of G protein-coupled receptor ternary complex dynamics / Larry Sklar16:
Expression and Functional Reconstitution of CCR1 / Samantha Allen17:
Characterization of the Interactions of Chemokines with Glycosaminoglycans by Fourier Transform Ion Cyclotron Resonance / Julie A. Leary18:
Chemokine Function in Cell Migration
In vitro assays for studying chemokine-triggered lymphocyte transendothelial migration under physiological flow conditions / Ronen Alon ; Francis Lin19:
Microfluidic device / Eugene Butcher20:
Two-photon imaging and quantitative analysis of leukocyte migration in vivo / Mark Miller ; Jenna Cash21:
Zymosan induced peritonitis as a model for studying chemokines and inflammatory mediators in vivo / David Greaves22:
Structure and Function
A Novel Chemokine-mediated In Vivo T Cell Recruitment Assay for Structure Function Studies / Andrew D. Luster ; Gabriele Campanella1:
Tyrosine sulfation of HIV-1 coreceptors and other chemokine-binding receptors / Micheal R. Farzan2:
13.

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Damon J. Hamel, Tracy M. Handel
出版情報: Elsevier ScienceDirect Books , 2009
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Contributors
Preface
Volumes in Series
Chemokines and Receptors in Disease / Section I:
Chemokines in Human Breast Tumor Cells: Modifying Their Expression Levels and Determining Their Effects on the Malignancy Phenotype / Gali Soria ; Tsipi Meshel ; Adit Ben-Baruch1:
Introduction
Modifying Chemokine Expression in Breast Tumor Cells / 2:
Establishment of Primary Local Breast Tumors and Pulmonary Metastases / 3:
Acknowledgments
References
CCR5 Pharmacology Methodologies and Associated Applications / Roy Mansfield ; Sarah Able ; Paul Griffin ; Becky Irvine ; Ian James ; Malcolm Marcartney ; Ken Miller ; James Mills ; Carolyn Napier ; Iva Navratilova ; Manos Perros ; Graham Rickett ; Harriet Root ; Elna van der Ryst ; Mike Westby ; Patrick Dorr
CCR5 Signaling Assays and Application to Quantify and Characterize Ligand-Dependent Agonism, Antagonism, and Inverse Agonism
CCR5-Associated Ligand-Binding Assays
Surrogate In Vitro Antiviral Assays / 4:
CCR5 Site-Directed Mutagenesis and Ligand Docking Studies / 5:
Non-HIV Indications-Associated Studies, Human CCR5 Knock-In Mice / 6:
CXCR4 and Mobilization of Hematopoietic Precursors / Michael P. Rettig ; Pablo Ramirez ; Bruno Nervi ; John F. DiPersio
HSPC Mobilizing Agents that Target the CXCL12/CXCR4 Axis
Donor Selection for HSPC Mobilization
Flow Cytometric Enumeration of Mobilized HSPCs
Dosing and Kinetics of HSPC Mobilization by G-CSF and Plerixafor
Functional Characterization of Mobilized HSPCs / 7:
Concluding Remarks / 8:
Acknowledgment
Double-Label Nonradioactive In Situ Hybridization for the Analysis of Chemokine Receptor Expression in the Central Nervous System / Meizhang Li ; Richard M. Ransohoff
Basic Protocol for ISH (Using Digoxygenin-Labeled Probe)
Comments
Expression of Chemokines and Chemokine Receptors in Human Colon Cancer / Marco Erreni ; Paolo Bianchi ; Luigi Laghi ; Massimiliano Mirolo ; Marco Fabbri ; Massimo Locati ; Alberto Mantovani ; Paola Allavena
Materials and Methods
Results
Discussion
Chemokine Related Proteins from Pathogens / Section II:
Kaposi's Sarcoma Virally Encoded, G-Protein-Coupled Receptor: A Paradigm for Paracrine Transformation / Daniel Martin ; J. Silvio Gutkind
Cloning of vGPCR
Assaying vGPCR Transforming Activity In Vitro
vGPCR Transforming Activity In Vivo Using Xenograft Systems
In Vivo Targeted Infection Using the TVA-RCAS System
vGPCR-Induced Paracrine Transformation
Characterization of vGPCR-Induced Molecular Signaling
Evaluation of Activation of Second-Messenger-Generating Systems
Activation of Signal-Transducing Protein Kinases and Small GTPases / 9:
Akt Kinase Assay / 10:
vGPCR Stimulated Activation of Rac1-Pulldown Assays / 11:
Western Blotting Using Phospho-Specific Antibodies / 12:
Activation of Transcription Factors / 13:
Global Changes in Gene Expression: Microarray Analysis / 14:
NFkB Luciferase Assays / 15:
NFkB Binding Assays / 16:
Nuclear Translocation of NFkB / 17:
Pharmacological and Biochemical Characterization of Human Cytomegalovirus-Encoded G Protein-Coupled Receptors / David Maussang ; Henry F. Vischer ; Andreas Schreiber ; Detlef Michel ; Martine J. Smit
Virally Encoded GPCR Engineering
vGPCR Expression, Trafficking, and Radioligand Binding
vGPCR-Induced Signal Transduction
vGPCR-Induced Oncogenesis
Generation of Recombinant HCMV Strains by Markerless Bacterial Artificial Chromosome Mutagenesis
Conclusions
Identification and Characterization of Virus-Encoded Chemokine Binding Proteins / Antonio Alcami ; Abel Viejo-Borbolla
Methods for Studying Chemokine-Binding Proteins
The Chemokine-Binding Protein M3 as a Tool to Understand the Chemokine Network In Vivo / Sergio A. Lira ; Limin Shang ; Andrea P. Martin
Generation of Transgenic Mice Expressing M3 in Insulin-Producing b Cells
M3 Expression in Islets of Langerhans Blocks CCL2-, CCL21-, and CXCL13-Induced Migration of Cells to Islets
M3 Expression in b Cells Blocks Cellular Infiltration and Prevents Diabetes Development
Generation of a Conditional Transgenic System for Expression of M3
M-T7: Measuring Chemokine-Modulating Activity / Mee Y. Bartee ; Erbin Dai ; Liying Liu ; Ganesh Munuswamy-Ramanujam ; Colin Macaulay ; Dana Mclvor ; Grant McFadden ; Alexandra R. Lucas
Protein Expression
Quantifying the Effects of M-T7 In Vitro and Ex Vivo
Quantifying the Effects of M-T7 on Vascular Inflammatory Responses in Rodent Vascular Transplant Models
Preclinical Toxicity Testing
Atypical and Novel Chemoattractants and Receptors / Section III:
Role of the Chemokine Scavenger Receptor D6 in Balancing Inflammation and Immune Activation / Elena M. Borroni ; Chiara Buracchi ; Benedetta Savino ; Fabio Pasqualini ; Remo C. Russo ; Manuela Nebuloni ; Raffaella Bonecchi
Methods
Structure-Function Dissection of D6, an Atypical Scavenger Receptor / Robert J. B. Nibbs ; Pauline McLean ; Clare McCulloch ; Alan Riboldi-Tunnicliffe ; Emma Blair ; Yanshi Zhu ; Neil Isaacs ; Gerard J. Graham
Modeling Small Molecule-Compound Binding to G-Protein-Coupled Receptors / Nagarajan Vaidehi ; James E. Pease ; Richard Horuk
Similarity and Differences in the Crystal Structures of Class-A GPCRs Solved to Date
GPCR Modeling Methods
Computational Methods for Receptor Flexibility and Ligand-Induced Conformational Changes in GPCRs
Validation of GPCR-Ligand Models
Elucidation of Chemerin and Chemokine-Like Receptor-1 Function in Adipocytes by Adenoviral-Mediated shRNA Knockdown of Gene Expression / Kerry B. Goralski ; Christopher J. Sinal
The 3T3-L1 Cell Model for Adipogenesis and Adipocyte Metabolism
RNA Interference
Methods for Adenoviral shRNA Knockdown of Chemerin and CMKLR1 in 3T3-L1 Cells
Chemokine Signaling / Section IV:
Characterization of Chemokine Receptor CXCR2 Interacting Proteins Using a Proteomics Approach to Define the CXCR2 "Chemosynapse" / Dayanidhi Raman ; Nicole F. Neel ; Jiqing Sai ; Raymond L. Mernaugh ; Amy-Joan L. Ham ; Ann J. Richmond
Validation of the Interaction of Novel Proteins with CXCR2
Mutational Analysis of Residues at Interactive Interface of CXCR2 and CXCR2-Binding Proteins
Radioactive Phosphorylation of CXCR2 Interacting Proteins
Chemotaxis Assay
Phosphoproteomic Analysis of Chemokine Signaling Networks / Morgan O'Hayre ; Catherina L. Salanga ; Pieter C. Dorrestein ; Tracy M. Handel
Summary
Monitoring NF-kB Mediated Chemokine Transcription in Tumorigenesis / Jinming Yang
Development of NF-kB Reporter Model for Tumors
Bioluminescent Imaging of Intratumor Signaling of Anesthetized Mice
Cell-Based Assays for Kinase and Transcriptional Activity In Vitro
Peripheral Spying of Intratumoral Signaling of Conscious Mice
Analysis of Chemokine Receptor Endocytosis and Intracellular Trafficking / Tom Kershaw ; Silene T. Wavre-Shapton ; Nathalie Signoret ; Mark Marsh18:
Receptor Detection
Cells
Monitoring Receptor Endocytosis
Monitoring Receptor Recycling
Monitoring Receptor Degradation
Electron Microscopy Analysis of Receptor Internalization
Measuring the Proximity of T-Lymphocyte CXCR4 and TCR by Fluorescence Resonance Energy Transfer (FRET) / Ashok Kumar ; Kimberly N. Kremer ; Olivia L. Sims ; Karen E. Hedin19:
Assaying CXCR4-TCR Proximity via the PE/APC mAb FRET Approach
Assaying CXCR4-TCR Proximity via the CFP/YFP Fusion Protein Approach
Expression of CXCR4, a G-Protein-Coupled Receptor for CXCL12 in Yeast: Identification of New-Generation Inverse Agonists / Barry J. Evans ; Zixuan Wang ; James R. Broach ; Shinya Oishi ; Nobutaka Fujii ; Stephen C. Peiper20:
Methods and Discussion
Ubiquitination of Chemokine Receptors / Adriano Marchese21:
Cell Culture and Transfections
Agonist Treatment and Ubiquitination Assay
E3 Ubiquitin Ligase AIP4 Mediates Ubiquitination of CXCR4
Author Index
Subject Index
Contributors
Preface
Volumes in Series
14.

電子ブック

EB
Daniel J. Klionsky
出版情報: Elsevier ScienceDirect Books , 2009
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Contributors
Preface
Volumes in Series
Initiation of Autophagy by Photodynamic Therapy / David Kessel ; Nancy L. Oleinick1:
Introduction
Photosensitizing Agents / 2:
Additional Factors Unique to PDT / 3:
A Typical PDT Protocol / 4:
Identification and Characterization of Autophagy after PDT / 5:
Effects of Autophagy on PDT Responses / 6:
Acknowledgments
References
Autophagic Cell Death / Michael J. Lenardo ; Christina K. McPhee ; Li Yu
Methods to Quantify Cell Death
Methods to Measure Autophagy
Methods to Establish Autophagy as the Cause of Cell Death
Autophagy Genes for RNAi Silencing
Transfact RNAi by Electroporation (Amaxa Nucleofection)
Conclusion / 7:
Autophagic Neuron Death / Yasuo Uchiyama ; Masato Koike ; Masahiro Shibata ; Mitsuho Sasaki
Experimental Models of Neurodegeneration
Measurements of Neuron Death
Assessing Metabolic Stress and Autophagy Status in Epithelial Tumors / Robin Mathew ; Vassiliki Karantza-Wadsworth ; Eileen White
Mouse Epithelial Cell Models for Studying the Role of Autophagy in Cancer
Protocols for Monitoring Autophagy in iBMK Cells and iMMECs In Vitro
Protocols for Monitoring Autophagy in Tumors In Vivo
Monitoring Chromosomal Instability Due to Autophagy Defects
Concluding Remarks and Future Perspectives
Autophagic Clearance of Aggregate-Prone Proteins Associated with Neurodegeneration / Sovan Sarkar ; Brinda Ravikumar ; David C. Rubinsztein
Aggregate-Prone Intracytoplasmic Proteins Associated with Neurodegenerative Disorders are Autophagy Substrates
Assays for the Clearance of Aggregate-Prone Proteins
Measurement of Autophagic Flux Using Bafilomycin A1
Concluding Remarks
Acknowledgements
Monitoring Autophagy in Alzheimer's Disease and Related Neurodegenerative Diseases / Dun-Sheng Yang ; Ju-Hyun Lee ; Ralph A. Nixon
General Approaches to Investigations of Human Neurodegeneration
Characterization of Autophagic Vacuoles, Evaluation of Autophagosome and Autolysosome Formation, and Autolysosomal Clearance
Metabolic Analyses of Autophagy in Neuronal and Nonneuronal Cell Models
Isolation and Characterization of Autophagic Vacuoles and Lysosomes from Cell Cultures and Brain Tissue
Western Blot Analysis of Autophagy Components and Substrates
Live-Cell Imaging of Autophagy Induction and Autophagosome-Lysosome Fusion in Primary Cultured Neurons / Mona Bains ; Kim A. Heidenreich
Cultured Cerebellar Purkinje Neurons as a Model to Study Neuronal Autophagy
Characterization of Autophagic Vacuole Size and Number in Purkinje Neurons
Using Colocalization of Fluorescent Tags to Measure Autophagosome-Lysosome Fusion
Using Genetic Mouse Models to Study the Biology and Pathology of Autophagy in the Central Nervous System / Zhenyu Yue ; Gay R. Holstein ; Brian T. Chait ; Qing Jun Wang8:
Methods
Analysis of GFP-LC3 Expression and Subcellular Localization in the CNS
Analysis of p62/SQSTM1 and Ubiquitinated Protein Inclusions in the CNS
Transmission Electron Microscopy (TEM) Analysis of Autophagosomes
Biochemical and Morphological Detection of Inclusion Bodies in Autophagy-Deficient Mice / Satoshi Waguri ; Masaaki Komatsu9:
Detection of Ubiquitinated Proteins and p62 in Autophagy-Deficient Mice by Western Blot Analysis
Detection of Ubiquitinated Proteins and p62 in Cultured Hepatocytes Derived from Autophagy-Deficient Mice
Detection of Ubiquitin-and p62-Positive Inclusions at the Light Microscopy Level
Detection of Ubiquitin-and p62-Positive Inclusions at the Electron Microscopy Level
Analyzing Autophagy in Clinical Tissues of Lung and Vascular Diseases / Hong Pyo Kim ; Zhi-Hua Chen ; Augustine M. K. Choi ; Stefan W. Ryter10:
Methods for Preparation of Lung and Vascular Cells
Analysis of Autophagy
Chromatin Immunoprecipitation
Conclusions
Autophagy in Neurite Injury and Neurodegeneration: In Vitro and In Vivo Models / Charleen T. Chu ; Edward D. Plowey ; Ruben K. Dagda ; Robert W. Hickey ; Salvatore J. Cherra ; Robert S. B. Clark11:
Studying Neuronal Autophagy In Vitro
Studying Brain Autophagy In Vivo
Future Perspectives and Challenges
Monitoring the Autophagy Pathway in Cancer / Frank C. Dorsey ; Meredith A. Steeves ; Stephanie M. Prater ; Thomas Schröter ; John L. Cleveland12:
LC3: A Phenotypic and Functional Marker of Autophagy
Assessing the Role of Autophagy in E&umu;-Myc-Driven Lymphoma
Autophagy Pathways in Glioblastoma / Hong Jiang ; Erin J. White ; Charles Conrad ; Candelaria Gomez-Manzano ; Juan Fueyo13:
Introduction: Autophagy and Gliomas
Prioritization of Methods to Characterize Autophagy in Gliomas
In Vitro Cellular Markers
In Vitro Biochemical Markers
Electron Microscopy to Monitor the Autophagic Vacuoles
In Vivo Analysis of Biochemical Markers
Autophagy Indicators as Surrogate Markets of Treatment Effect in Clinical Trials
Future Directions
Autophagy in Lung Cancer / Jerry J. Jaboin ; Misun Hwang ; Bo Lu14:
Signal-Dependant Control of Autophagy-Related Gene Expression / Fulvio Chiacchiera ; Cristiano Simone15:
Overview: Signal Transduction and Chromatin-Associated Kinases
The p38 Pathway in Colorectal Cancer Cells
Methods to Test Kinase Activity
Profiling Gene Expression Pattern
Transcriptional Control of ATG Genes
Analysis of Transcriptional Multiprotein Complexes
Novel Methods for Measuring Cardiac Autophagy In Vivo / Cynthia N. Perry ; Shiori Kyoi ; Nirmala Hariharan ; Hiromitsu Takagi ; Junichi Sadoshima ; Roberta A. Gottlieb16:
In Vivo Models of Autophagy in the Myocardium
Discussion
Autophagy in Load-Induced Heart Disease / Hongxin Zhu ; Beverly A. Rothermel ; Joseph A. Hill17:
Mouse Models of Load-Induced Heart Disease
Analysis of Ventricular Remodeling
In Vitro Models of Load-Induced Hypertrophy
Techniques to Analyze Cardiomyocyte Autophagy
Immunohistochemistry for LAMP-1 or Cathepsin D to Monitor Changes in Lysosomal Abundance
Isolation of LC3 Proteins from NRVM in Culture
Isolation of LC3 Protein from Heart of Skeletal Muscle Tissue
Soluble/Insoluble Fractionation of NRVM
Perspective
Evaluation of Cell Death Markers in Severe Calcified Aortic Valves / Wilhelm Mistiaen ; Michiel Knaapen18:
Clinical Importance of Degenerative Aortic Valve Disease
Pathological Appearances of AVD
Mechanism of Progression of AVD
Autophagy: Major Player in the Progression of Aortic Valve Disease?
Methods for Detection of Cell Death Markers in the Degenerated Aortic Valve
Methods for Quantification of Calcified Aortic Valves
Prospects and Concluding Remarks
Monitoring Autophagy in Muscle Diseases / May Christine V. Malicdan ; Satoru Noguchi ; Ichizo Nishino19:
Histological Observation of Skeletal Muscles
Measuring Autophagy by Protein Quantification
Monitoring Autophagy in Cultured Skeletal Myocytes
Electron Microscopy Observation of Skeletal Muscles
Immunoelectron Microscopy
Analyzing Macroautophagy in Hepatocytes and the Liver / Wen-Xing Ding ; Xiao-Ming Yin20:
The Pathophysiological Relevance of Macroautophagy in the Liver
Analysis of Autophagy in Isolated Hepatocytes
Analysis of Autophagy in the Liver
Summary
Monitoring Autophagy in Lysosomal Storage Disorders / Nina Raben ; Lauren Shea ; Victoria Hill ; Paul Plotz21:
General Techniques to Monitor Autophagy In LSDs
LSDs Analyzed for Autophagic Involvement
Author Index
Subject Index
Contributors
Preface
Volumes in Series
15.

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Nejat DÃ〓zgÃ〓neÅ
出版情報: Elsevier ScienceDirect Books , Elsevier LTD., 2009
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Contributors
Preface
Volumes in Series
Bioactive Liposomes / Section I:
Tubular Liposomes with Variable Permeability for Reconstitution of FtsZ Rings / Masaki Osawa ; Harold P. Erickson1:
Introduction
Reagents / 2:
Bacterial Expression of Membrane Targeting FtsZ / 3:
Purification of FtsZ-mts and FtsZ-YFP-mts / 4:
Renatured Preparation of FtsZ-YFP-mts / 5:
Tubular Multilamellar Liposome Preparation / 6:
Permeability of the Multilamellar Liposomes / 7:
Z-ring Formation in Liposomes / 8:
A Crude Flow Chamber to Exchange Buffer Outside Liposomes / 9:
Factors Affecting Z-ring Formation in Liposomes / 10:
Utility of the Liposomes Beyond FtsZ / 11:
References
Detection and Analysis of Protein Synthesis and RNA Replication in Giant Liposomes / Takeshi Sunami ; Hiroshi Kita ; Kazufumi Hosoda ; Tomoaki Matsuura ; Hiroaki Suzuki ; Tetsuya Yomo
Methods
Analysis of the FACS Data
Conclusions
Acknowledgments
Construction of Cell-Sized Liposomes Encapsulating Actin and Actin-Cross-Linking Proteins / Kingo Takiguchi ; Ayako Yamada ; Makiko Negishi ; Makoto Honda ; Yohko Tanaka-Takiguchi ; Kenichi Yoshikawa
Experimental Section
Morphogenesis of Giant Liposomes Encapsulating Actin and Its Cross-linking Proteins
Concluding Remarks
Reconstitution of Membrane Budding with Unilamellar Vesicles / Anna V. Shnyrova ; Joshua Zimmerberg
M Protein Purification
Evaluation of the Membrane Activity of M Protein Through its Interaction with Intermediate-Sized Unilamellar Liposomes
Reconstitution of M-Protein-Driven Membrane Budding on GUVs
Liposomes and Nanotechnology / Section II:
Detection of Antimycolic Acid Antibodies by Liposomal Biosensors / Y. Lemmer ; S. T. Thanyani ; P. J. Vrey ; C. H. S. Driver ; L. Venter ; S. van Wyngaardt ; A. M. C. ten Bokum ; K. I. Ozoemena ; L. A. Pilcher ; D. G. Fernig ; A. C. Stoltz ; H. S. Swai ; J. A. Verschoor
Experimental
Conclusion
Solid Lipid Nanoparticle Formulations: Pharmacokinetic and Biopharmaceutical Aspects in Drug Delivery / Eliana B. Souto ; Slavomira Doktorovová
Production of SLN
Pharmacokinetics and Pharmacodynamics
Modified Release Profile
Biopharmaceutical Aspects of Administration Routes
Clinical Pharmacology
Preparation of Complexes of Liposomes with Gold Nanoparticles / Chie Kojima ; Yusuke Hirano ; Kenji Kono
Preparation of Complexes of EYPC Liposomes with Au NPs
Time-Dependent SPR of the Complexes
TEM Analysis of the Complexes
DLS Analysis of the Complexes
Calcein Release from the Complexes
Estimation of Numbers of the Au NP and the Liposome in the Complexes
Optimization of Lipid Components of the Complexes
Acknowledgment
Bio-Nanocapsule-Liposome Conjugates for In Vivo Pinpoint Drug and Gene Delivery / Takeshi Kasuya ; Joohee Jung ; Rie Kinoshita ; Yasumasa Goh ; Takashi Matsuzaki ; Masumi lijima ; Nobuo Yoshimoto ; Katsuyuki Tanizawa ; ShunÆichi Kuroda
First-Generation Bio-Nanocapsules
Second-Generation BNCs
Retargeting of BNC-LP Conjugates
Overexpression of BNCs in S. cerevisiae
Conjugation of BNCs with LPs
Preparation of Antibody-Displaying BNC-LP Conjugates
Preparation of Biotin-Displaying BNC-LP Conjugates
Nanoliposomal Dry Powder Formulations / Gaurang Patel ; Mahavir Chougule ; Mandip Singh ; Ambikanandan Misra
Preparation of Nanoliposomal DPFs
Physicochemical Characterization of NLDPFs
Lanthanide-Loaded Paramagnetic Liposomes as Switchable Magnetically Oriented Nanovesicles / Silvio Aime ; Daniela Delli Castelli ; Enzo Terreno
Paramagnetic Ln(III)-Based Shift Reagents
Preparation of Osmotically Shrunken Liposomes
NMR Characterization of Magnetically Oriented Nonspherical Liposomes
Sample Experiments
Reconstitution of Membrane Proteins in Phospholipid Bilayer Nanodiscs / T. K. Ritchie ; Y. V. Grinkova ; T. H. Bayburt ; I. G. Denisov ; J. K. Zolnerciks ; W. M. Atkins ; S. G. Sligar
Overview of Nanodisc Technology
Reconstitution Considerations
Optimizing the Reconstitution for P-glycoprotein
DMA-Controlled Assembly of Liposomes in Diagnostics / 12:
Ulla Jakobsen and Stefan Vogel
Probe Design
General Description of Materials and Techniques
Soft Hybrid Nanostructures Composed of Phospholipid Liposomes Decorated with Oligonucleotides / Martina Banchelli ; Francesca Baldelli Bombelli ; Debora Berti ; Piero Baglioni13:
Materials
Liposome Preparation and Determination of Lipid Content
Incorporation of Oligonucleotides
Characterization of the Soft Hybrid Nanostructure
Applications of Oligo-Decorated Liposomes
Challenges and Perspectives
Synthesis, Characterization, and Optical Response of Gold Nanoshells Used to Trigger Release from Liposomes / Guohui Wu ; Alexander Mikhailovsky ; Htet A. Khant ; Joseph A. Zasadzinski14:
Synthesis of HGNs
Optimization of HGN Dimensions for Maximum Absorption in the NIR
HGN Response to Femtosecond NIR Laser Pulses
Coupling HGN to Liposomes
Liposome Disruption and CF Release Due to Pulsed Laser Irradiation
Mechanism of Triggered Liposome Release
Effect of Proximity of HGNs to Liposomes
Complex Nanotube-Liposome Networks / Aldo Jesorka ; Owe Orwar15:
Network Fabrication Protocols
Complexity and Topology
Internal and Membrane Functionalization
Transport Phenomena and Controlled Mixing Procedures
Enzymatic Reactions in NVN
Bionanotubules Formed from Liposomes / Josemar A. Castillo ; Mark A. Hayes16:
Bionanotubule Formation by Applying Electric Fields to Surface-Attached Liposomes
Bionanotubular Formation from Liposomes in Solution Using Electric Fields
Other Methods of Bionanotubular Formation from Liposomes
Engineering Cationic Liposome: siRNA Complexes for In Vitro and In Vivo Delivery / Jennifer E. Podesta ; Kostas Kostarelos17:
Cationic Liposome Systems for siRNA Delivery
Experimental Methods
Troubleshooting
Author Index
Subject Index
Contributors
Preface
Volumes in Series
16.

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Michael L. John, Ludwig Brand, Michael L. Johnson
出版情報: Elsevier ScienceDirect Books , Elsevier Science & Technology, 2009
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Contributors
Preface
Volumes in Series
Correlation Analysis: A Tool for Comparing Relaxation-Type Models to Experimental Data / Maurizio Tomaiuolo ; Joel Tabak ; Richard Bertram1:
Introduction
Scatter Plots and Correlation Analysis / 2:
Example 1: Relaxation Oscillations / 3:
Example 2: Square Wave Bursting / 4:
Example 3: Elliptic Bursting / 5:
Example 4: Using Correlation Analysis on Experimental Data / 6:
Summary / 7:
Acknowledgments
References
Trait Variability of Cancer Cells Quantified by High-Content Automated Microscopy of Single Cells / Vito Quaranta ; Darren R. Tyson ; Shawn P. Garbett ; Brandy Weidow ; Mark P. Harris ; Walter Georgescu
Background
Experimental and Computational Workflow
Application to Traits Relevant to Cancer Progression
Conclusions
Matrix Factorization for Recovery of Biological Processes from Microarray Data / Andrew V. Kossenkov ; Michael F. Ochs
Overview of Methods
Application to the Rosetta Compendium
Results of Analyses
Discussion
Modeling and Simulation of the Immune System as a Self-Regulating Network / Peter S. Kim ; Doron Levy ; Peter P. Lee
Mathematical Modeling of the Immune Network
Two Examples of Models to Understand T Cell Regulation
How to Implement Mathematical Models in Computer Simulations
Concluding Remarks
Acknowledgmentss
Entropy Demystified: The ôThermoö-dynamics of Stochastically Fluctuating Systems / Hong Qian
Energy
Entropy and ôThermoö-dynamics of Markov Processes
A Three-State Two-Cycle Motor Protein
Phosphorylation-Dephosphorylation Cycle1 Kinetics
Summary and Challenges
Effect of Kinetics on Sedimentation Velocity Profiles and the Role of Intermediates / John J. Correia ; P. Holland Alday ; Peter Sherwood ; Walter F. Stafford
Methods
ABCD Systems
Monomer-Tetramer Model
Algebraic Models of Biochemical Networks / Reinhard Laubenbacher ; Abdul Salam Jarrah
Computational Systems Biology
Network Inference
Reverse-Engineering of Discrete Models: An Example
High-Through put Computing in the Sciences / Mark Morgan ; Andrew Grimshaw8:
What is an HTC Application?
HTC Technologies
High-Throughput Computing Examples
Advanced Topics
Large Scale Transcriptome Data Integration Across Multiple Tissues to Decipher Stem Cell Signatures / Ghislain Bidaut ; Christian J. Stoeckert9:
Systems and Data Sources
Data Integration
Artificial Neural Network Training and Validation
Future Development and Enhancement Plans
DynaFit-A Software Package for Enzymology / Petr Kuzmiĉ10:
Equilibrium Binding Studies
Initial Rates of Enzyme Reactions
Time Course of Enzyme Reactions
General Methods and Algorithms
Discrete Dynamic Modeling of Cellular Signaling Networks / Réka Albert ; Rui-Sheng Wang11:
Cellular Signaling Networks
Boolean Dynamic Modeling
Variants of Boolean Network Models
Application Examples
Conclusion and Discussion
The Basic Concepts of Molecular Modeling / Akansha Saxena ; Diana Wong ; Karthikeyan Diraviyam ; David Sept12:
Homology Modeling
Molecular Dynamics
Molecular Docking
Deterministic and Stochastic Models of Genetic Regulatory Networks / Ilya Shmulevich ; John D. Aitchison13:
Boolean Networks
Differential Equation Models
Probabilistic Boolean Networks
Stochastic Differential Equation Models
Bayesian Probability Approach to ADHD Appraisal / Raina Robeva ; Jennifer Kim Penberthy14:
Bayesian Probability Algorithm
The Value of Bayesian Probability Approach as a Meta-Analysis Tool
Discussion and Future Directions
Simple Stochastic Simulation / Maria J. Schilstra ; Stephen R. Martin15:
Understanding Reaction Dynamics
Graphical Notation
Reactions
Reaction Kinetics
Transition Firing Rules
Notes
Monte Carlo Simulation in Establishing Analytical Quality Requirements for Clinical Laboratory Tests: Meeting Clinical Needs / James C. Boyd ; David E. Bruns16:
Modeling Approach
Methods for Simulation Study
Results
Nonlinear Dynamical Analysis and Optimization for Biological/Biomedical Systems / Amos Ben-Zvi ; Jong Mm Lee17:
Hypothalamic-Pituitary-Adrenal Axis System
Development of a Clinically Relevant Performance-Assessment Tools
Dynamic Programming
Computation of Optimal Treatments for HPA Axis System
Modeling of Growth Factor-Receptor Systems: From Molecular-Level Protein Interaction Networks to Whole-Body Compartment Models / Florence T. H. Wu ; Marianne O. Stefanini ; Feilim Mac Gabhann ; Aleksander S. Popel18:
Molecular-Level Kinetics Models: Simulation of In Vitro Experiments
Mesoscale Single-Tissue 3D Models: Simulation of In Vivo Tissue Regions
Single-Tissue Compartmental Models: Simulation at In Vivo Tissue
Multitissue Compartmental Models: Simulation of Whole Body
The Least-Squares Analysis of Data from Binding and Enzyme Kinetics Studies: Weights, Bias, and Confidence Intervals in Usual and Unusual Situations / Joel Tellinghuisen19:
Least Squares Review
Statistics of Reciprocals
Weights When y is a True Dependent Variable
Unusual Weighting: When x is the Dependent Variable
Assessing Data Uncertainty: Variance Function Estimation
Conclusion
Nonparametric Entropy Estimation Using Kernel Densities / Douglas E. Lake20:
Motivating Application: Classifying Cardiac Rhythms
Renyi Entropy and the Friedman-Tukey Index
Kernel Density Estimation
Mean-Integrated Square Error
Estimating the FT Index
Connection Between Template Matches and Kernel Densities
Summary and Future Work
Pancreatic Network Control of Glucagon Secretion and Counterregulation / Leon S. Farhy ; Anthony L. McCall21:
Mechanisms of Glucagon Counterregulation (GCR) Dysregulation in Diabetes
Interdisciplinary Approach to Investigating the Defects in the GCR
Initial Qualitative Analysis of the GCR Control Axis
Mathematical Models of the GCR Control Mechanisms in STZ-Treated Rats
Approximation of the Normal Endocrine Pancreas by a Minimal Control Network (MCN) and Analysis of the GCR Abnormalities in the Insulin Deficient Pancreas
Advantages and Limitations of the Interdisciplinary Approach
Enzyme Kinetics and Computational Modeling for Systems Biology / Pedro Mendes ; Hanan Messiha ; Naglis Malys ; Stefan Hoops22:
Computational Modeling and Enzyme Kinetics
Yeast Triosephosphate Isomerase (EC 5.3.1.1)
Initial Rate Analysis
Progress Curve Analysis
Fitting Enzyme Kinetic Data with KinTek Global Kinetic Explorer / Kenneth A. Johnson23:
Challenges of Fitting by Simulation
Progress Curve Kinetics
Fitting Full Progress Curves
Slow Onset Inhibition Kinetics
Author Index
Subject Index
Contributors
Preface
Volumes in Series
17.

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Daniel Herschlag
出版情報: Elsevier ScienceDirect Books , Elsevier Science, 2009
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A Chemical and Enzymatic Footprinting of RNA Structure
Equilibrium hydroxyl radical footprinting / 1:
Bench-top time-resolved hydroxyl radical footprinting / 2:
Analysis of hydroxyl radical footprinting gels 'SAFA' / 3:
Kinetic modeling of reaction pathways from hydroxyl radical data / 4:
"BABE" mapping of protein/RNA position / 5:
Multiplexed..(MOHCA) / 6:
SHAPE / 7:
"In-line Probing" / 8:
NAIM / 9:
Other NAIM / 10:
Purification of T7 RNA Polymerase / 11:
Purification of T4 RNA ligase / 12:
In vitro transcription of RNA / 13:
32P-labeling of RNA B. BIOPHYSICAL TECHNIQUES / 14:
Fluorescent labeling of RNAs / 15:
Assembly of complex RNAs by 'Moore-Sharp' ligations / 16:
General considerations for smFRET with RNA samples / 17:
Ion counting / 19:
ASAXS / 20:
NLPB / 21:
smNLPB / 22:
Gel mobility mapping of junction structure / 23:
Temperature gradient gels / 24:
Melting studies / 25:
Co-transcriptional folding studies / 26:
Activity assays to follow folding processes / 27:
2AP fluorescence / 28:
EPR measurements of RNA dynamics / 29:
FPA measurements of RNA dynamics / 30:
EPR methods to study specific metal ion binding sites in RNA / 32:
Thermodynamic study of site-specific metal ion binding sites in RNA / 33:
Oligonucleotide hybridization studies of RNA folding pathways / 34:
Native gel shifts / 35:
Tiling arrays to assess RNA structure / 36:
EPR distance measurements in RNA / 37:
RNA folding in vivo / 38:
Cleavage of RNAs with 'restriction DNAzymes' / 39:
A Chemical and Enzymatic Footprinting of RNA Structure
Equilibrium hydroxyl radical footprinting / 1:
Bench-top time-resolved hydroxyl radical footprinting / 2:
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Nejat DÃ〓zgÃ〓neÅ
出版情報: Elsevier ScienceDirect Books , Elsevier Science, 2009
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Contributors
Preface
Volumes in Series
Advances in Liposome Formation and Characterization / Section I:
Spontaneously Formed Unilamellar Vesicles / Mu-Ping Nieh ; Norbert Kucerka ; John Katsaras1:
Introduction
Preparation of Spontaneously Forming ULVs / 2:
Characteriiation of ULVs / 3:
ULV Stability / 4:
Parameters Affecting ULVs / 5:
Mechanism of ULV Formation / 6:
Encapsulation and Controlled Release Mechanism of Spontaneously Formed ULVs / 7:
Application / 8:
Concluding Remarks / 9:
Acknowledgement
References
Use of Acoustic Sensors to Probe the Mechanical Properties of Liposomes / Kathryn Melzak ; Achilleas Tsortos ; Electra Gizeli
Acoustic Measurements
Experimental Procedures
Change in ?Ph and ?A for Adsorbed Vesicles as a Function of Cholesterol Content
Comparison of the Results to Various Model Systems
Can the Response Be Explained in Terms of Variable Slip at the Surface?
Displacements Associated with the Liposomes
Acknowledgments
Liposome Characterization by Quartz Crystal Microbalance Measurements and Atomic Force Microscopy / Patrick Vermette
Liposomes Assessed by AFM
QCM Measurements of Intact Liposomes
Surface-Bound Liposomes in Perspective and General Conclusions
Mixing Solutions in Inkjet Formed Vesicles / Thomas H. Li ; Jeanne C. Stachowiak ; Daniel A. Fletcher
Unilamellar Vesicle Formation by Microfluidic Encapsulation
Determination of Encapsulation Fraction within Vesicles
Recombinant Proteoliposomes Prepared Using Baculovirus Expression Systems / Kanta Tsumoto ; Tetsuro Yoshimura
Principles of Recombinant Proteoliposome Preparation
Construction of Recombinant AcNPVs
Expression of Recombinant Proteins on BV Envelopes
Preparation of Proteoliposomes by Fusion of BVs with Liposomes
Block Liposomes: Vesicles of Charged Lipids with Distinctly Shaped Nanoscale Sphere-, Pear-, Tube-, or Rod-Segments / Alexandra Zidovska ; Kai K. Ewert ; Joel Quispe ; Bridget Carragher ; Clinton S. Potter ; Cyrus R. Safinya
Liposome Preparation
Microscopy
Design and Synthesis of MVLBG2
Phase Behavior of MVLBG2/DOPC Lipid Mixtures
Microfluidic Methods for Production of Liposomes / Bo Yu ; Robert J. Lee ; L. James Lee
Conventional Technologies for Production of Liposomes
Microfluidic Technologies for Synthesis of Nanoparticles
Microfluidic Technologies for Production of Liposomes
Constructing Size Distributions of Liposomes from Single-Object Fluorescence Measurements / Christina Lohr ; Andreas H. Kunding ; Vikram K. Bhatia ; Dimitrios Stamou
How Particle Size can be Obtained from Intensity Distributions
Vesicle Preparation and Immobilization
Image Acquisition
Image Processing
Intensity and Size Distributions
Multilamellarity Assay
Measuring Membrane-Curvature Selective Protein Binding
Giant Unilamellar Vesicle Electroformation: From Lipid Mixtures to Native Membranes Under Physiological Conditions / Philippe Meleard ; Luis A. Bagatolli ; Tanja Pott
General GUV Electroformation Protocol
Methods for GUV Electroformation from Lipid Mixtures, Liposomes, and Native Membranes
Liposomes in Therapeutics / Section II:
Liposomal Boron Delivery for Neutron Capture Therapy / Hiroyuki Nakamura10:
Boron-Encapsulation Approach
Boron Lipid-Liposome Approach
nido-Carborane Lipid Liposomes
Transferrin-Conjugated nido-Carborane Lipid Liposomes
closo-Dodecaborate Lipid Liposomes
Production of Recombinant Proteoliposomes for Therapeutic Uses / Lavinia Liguori ; Jean Luc Lenormand11:
Expression of Bak Protein Using a Bacterial Cell-Free Expression System
Scale-Up Production of Bak Proteoliposomes
Bak Proteoiiposome Production
Proteoiiposome Purification
Analysis of the Purified Bak Proteoliposomes
Transmission Electron Microscopy
Apoptosis Induction in Cancer Cell Lines: Caspase 9 Activation
Liposome-Mediated Therapy of Neuroblastoma / Daniela Di Paolo ; Monica Loi ; Fabio Pastorino ; Chiara Brignole ; Danilo Marimpietri ; Pamela Becherini ; Irene Caffa ; Alessia Zorzoli ; Renato Longhi ; Cristina Gagliani ; Carlo Tacchetti ; Angelo Corti ; Theresa M. Allen ; Mirco Ponzoni ; Gabriella Pagrian12:
Materials
Untargeted Liposomes Entrapping Doxorubicin
Tumor-Targeted Liposomal Chemotherapy
Vascular-Targeted Liposomal Chemotherapy
Liposomes Entrapping Fenretinide (HPR)
Antisense Oligonucleotide-Entrapped Liposomes
Gold-Containing Liposomes
Tumor-Specific Liposomal Drug Release Mediated by Liposomase / Ian Cheong ; Shibin Zhou13:
Tumor Models
Generation of C. novyi Spores and C. novyi-NT
Preparation of Liposomal Formulations
Combination Therapy with C. novyi-NT Spores and Liposomes
Purification and Identification of Liposomase
Conclusion and Future Perspectives
Targeted Lipoplexes for siRNA Delivery / Ana Cardoso ; Sara Trabulo ; João Nuno Moreira ; Nejat Düzgünes ; Maria C. Pedroso de Lima14:
Liposome and Complex Preparation
Physicochemical Characterization of the Complexes
Assessment of siRNA Protection
Assessment of Lipoplex Internalization and Biological Activity In Vitro
Cell Viability Studies
Mucosal Delivery of Liposome-Chitosan Nanoparticle Complexes / Edison L. S. Carvalho ; Ana Grenha ; Carmen Remuñán-Lápez ; Maria José Alonso ; Begoña Seijo15:
Preparation of Liposome-Chitosan Nanoparticle (L/CS-NP) Complexes
Characterization of (L/CS-NP) Complexes
Results
Conclusions and Prospects
Acknowledgment
Antiangiogenic Photodynamic Therapy with Targeted Liposomes / Naoto Oku ; Takayuki Ishil16:
PDT with PEG-Coated Liposomal BPD-MA
PDT with Polycation-Coated Liposomal BPD-MA
PDT with Tumor Angiogenic Vessel-Targeted Liposomal BPD-MA
Usefulness of Antiangiogenic PDT with Neovessel-Targeted Liposomes
Controlling the In Vivo Activity of Wnt Liposomes / L. Zhao ; S. M. Rooker ; N. Morrell ; P. Leucht ; D. Simanovskii ; A. Helms17:
Materials, Methods, and Results
Concluding Remarks 343 References
Convection-Enhanced Delivery of Liposomes to Primate Brain / Michal T. Krauze ; John Forsayeth ; Dali Yin ; and Krystof S. Bankiewicz18:
Quantification of Liposome-Entrapped Gadoteridol by Magnetic Resonance Imaging
Experimental Subjects
Infusion Catheter Design and Infusion Procedure
Distribution of Liposomes Within Anatomic Structures of the Primate Brain
Volumetric Calculations of Liposomal Distribution in Primate CNS
Future and Outlook of CED to Brain
Hemoglobin-Vesicles as an Artificial Oxygen Carrier / Hiromi Sakai ; Keitaro Sou ; Eishun Tsuchida19:
Introduction: Encapsulated Hemoglobin as an Artificial Oxygen Carrier
Encapsulation of Concentrated Hb in Liposomes
Source of Hb and Its Purification
Regulation of Oxygen Affinity
Structural Stabilization of Liposome-Encapsulated Hb
Blood Compatibility of LEH and HbV
Regulation of Osmotic Pressure and Suspension Rheology to Mimic and Overwhelm the Function of Blood
Author Index
Subject Index
Contributors
Preface
Volumes in Series
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International Conference on Optical Instruments and Technology, Yanbiao Liao, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Zhaoying Zhou, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Yunlong Sheng, Kimio Tatsuno, Yongtian Wang, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Xiaocong Yuan, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Xuping Zhang, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Tiegen Liu, Cunlin Zhang, Zhongguo yi qi yi biao xue hui.
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International Conference on Optical Instruments and Technology, Jun Ni, Shenghua Ye, Guangjun Zhang, Zhongguo yi qi yi biao xue hui.
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International Symposium on Advanced Optical Manufacturing and Testing Technologies, Li Yang, Zhongguo guang xue xue hui.
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International Symposium on Advanced Optical Manufacturing and Testing Technologies
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International Symposium on Advanced Optical Manufacturing and Testing Technologies
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International Symposium on Advanced Optical Manufacturing and Testing Technologies, Yudong Zhang, Zhongguo guang xue xue hui.
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Steven L. Chodos, William E. Thompson, SPIE (Society)
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Philip R. Hemmer, John R. Lowell, Selim M. Shahriar, SPIE (Society)
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R. Barry Johnson, Virendra N. Mahajan, Pantazis Mouroulis, SPIE (Society)
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Saša Bajt, Libor Juha, Ryszard H. Sobierajski, SPIE (Society)
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Toshio; Ishii, Yoshiharu Yanagida, Yoshiharu Ishii, Toshio Yanagida
出版情報: Wiley Online Library Online Books , 2009
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A Road Map to Single Molecule Dynamics Single Molecule
Study for Elucidating the Mechanism used by Biosystems to Utilize
Thermal Fluctuations Imaging and Molecular Motors
Ion Channel Signal Transduction across the Plasma
Membrane Dynamics of Membrane Receptors
Single Molecule Tracking of Quantum Dot Liganded
Epidermal Growth Factor Studying
Dynamics of Ligand-Receptor Complexes by Single-Molecule
Techniques RNA in Cells Protein
Dynamics and Interactions Two Rotary Motors of ATP
Synthase Single Molecule FRET
Studies of Helicases and Holliday
Junctions High-speed Atomic Force
Microscopy for Nano-visualization of Biomolecular
Processes Force-clamp Spectroscopy of Single Proteins
A Road Map to Single Molecule Dynamics Single Molecule
Study for Elucidating the Mechanism used by Biosystems to Utilize
Thermal Fluctuations Imaging and Molecular Motors
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Codd, Sarah Codd, Sarah L. Codd, Joseph D. Seymour, Sarah L.; Seymour, Joseph D. Codd
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Methods
Single Shot Imaging
Time of Flight 2D T2-T2
Exchange Shim Pulses
Materials
Building Materials
Paintings Textiles
Biopolymeric
Gels Food Plants Fuel Cells
Low Fields
Earths
Field Squids
Ultra Low Fields
Sensitivity DNP / Non-Equilibrium Polarisation:
Hyperpolarised
Gas Parahydrogen
Hardware
Magnet
Design
Innovations for Large Samples
Applications
Geophysics
Chemical Engineering
Reaction Kinetics
Electro-Osmotic
Flow Microfluids and Porous Media Biomedical
Dental Biofilms Freezing Processes
Mobile NMR
Compact MRI
Portable
Imaging
Single Sided
Spectroscopy
Methods
Single Shot Imaging
Time of Flight 2D T2-T2
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Woll, Christof Woll
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Coffee Table book of more than 300 large scale, dutone photographs of Nobel Prize
Winners such as / Nelson Mandela ; Dalai Lama ; John M. Coetzee ; Roy J. Glauber ; James
Watson or Jimmy Carter, each accompanied by a short biography written / Chris Richmond.
With an epilogue by Wim Wenders. Includes - as opposed to the former edition - the portraits of the 11 Nobel
Laureates of 2007. Accompanying texts: Alfred Nobel - the Will and the Prize (Anders Bßrßny, Deputy Director of the Nobel Museum, Stockholm)
The Lindau Meetings of Nobel Laureates - International Young Scientists Meet Nobel Laureates (Nikolaus Turner, Member of the Board of the "Council for the Lindau Nobel Laureate Meetings")
Coffee Table book of more than 300 large scale, dutone photographs of Nobel Prize
Winners such as / Nelson Mandela ; Dalai Lama ; John M. Coetzee ; Roy J. Glauber ; James
Watson or Jimmy Carter, each accompanied by a short biography written / Chris Richmond.
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Andre Moliton
出版情報: Wiley Online Library Online Books , Hoboken : John Wiley & Sons, Inc., 2009
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Peter Comba, Trevor W. Hambley, Bodo Martin
出版情報: Wiley Online Library Online Books , 2009
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Theory Introduction Molecular Modeling Methods in Brief Parameterization, Approximations and Limitations of Molecular Mechanics Computation
The Multiple Minima Problem Conclusions
Applications Structural Aspects Stereoselectivities
Metal Ion Selectivity Spectroscopy Electron Transfer Electronic Effects Bioinorganic Chemistry Organometallics Compounds with s,p and f Elements
Practice of Molecular Mechanics and DFT The Model, the Rules and the Pitfalls Tutorial References Appendices + CD with full software version and tutorial supplements
Theory Introduction Molecular Modeling Methods in Brief Parameterization, Approximations and Limitations of Molecular Mechanics Computation
The Multiple Minima Problem Conclusions
Applications Structural Aspects Stereoselectivities
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Kazunori Ozawa
出版情報: Wiley Online Library Online Books , 2009
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Preface
List of Contributors
General Concepts / Kenzo Matsuki ; Kazunori Ozawa1:
Brief Outline of Batteries / 1.1:
Galvanic Cell System - Aqueous Electrolyte System / 1.1.1:
Lithium-Cell System - Nonaqueous Electrolyte System / 1.1.2:
Early Development of Lithium-Ion Batteries / 1.2:
Ceramics Production Capability / 1.2.1:
Coating Technology / 1.2.2:
LiPF6 as a Salt for Electrolytes / 1.2.3:
Graphite Conductor in the Cathode / 1.2.4:
Using Hard Carbon for the Anode / 1.2.5:
Nonwoven Shut-down Separator / 1.2.6:
Ni-Plated Fe Can / 1.2.7:
Toward a Realistic Goal / 1.3:
References
Lithium Insertion Materials Having Spinel-Framework Structure for Advanced Batteries / Kingo Ariyoshi ; Yoshinari Makimura ; Tsutomu Ohzuku2:
Introduction / 2.1:
Structural Description of Spinel / 2.2:
Derivatives of Spinel-Framework Structure / 2.3:
Superlattice Structures Derived from "Spinel" / 2.3.1:
Examples of Superstructure Derived from "Spinel" / 2.3.2:
Electrochemistry of Lithium Insertion Materials Having Spinel-Framework Structure / 2.4:
Lithium Manganese Oxides (LMO) / 2.4.1:
Lithium Titanium Oxide (LTO) / 2.4.2:
Lithium Nickel Manganese Oxide (LiNiMO) / 2.4.3:
An Application of Lithium Insertion Materials Having Spinel-Framework Structure to 12 V "Lead-Free" Accumulators / 2.5:
Twelve-Volt Batteries Consisting of Lithium Titanium Oxide (LTO) and Lithium Manganese Oxide (LMO) / 2.5.1:
Twelve-Volt Batteries Consisting of Lithium Titanium Oxide (LTO) and Lithium Nickel Manganese Oxide (LiNiMO) / 2.5.2:
Concluding Remarks / 2.6:
Overlithiated Li1+x(Niz Co1-2ZMnz)1-xO2 as Positive Electrode Materials for Lithium-Ion Batteries / Naoaki Kumagai ; Jung-Min Kim3:
Co-Free Li1+x (Ni1/2Mn1/2)1-xO2 / 3.1:
Li1+x (Ni1/3Co1/3Mn1/3)1-xO2 / 3.3:
Other Li1+x(NizCo1-2zMnz)1-xO2 Materials / 3.4:
Conclusion / 3.5:
Iron-Based Rare-Metal-Free Cathodes / Shigeto Okada ; Jun-ichi Yamaki4:
2D Layered Rocksalt-Type Oxide Cathode / 4.1:
3D NASICON-Type Sulfate Cathode / 4.3:
3D Olivine-Type Phosphate Cathode / 4.4:
3D Calcite-Type Borate Cathode / 4.5:
3D Perovskite-Type Fluoride Cathode / 4.6:
Summary / 4.7:
Thermodynamics of Electrode Materials for Lithium-Ion Batteries / Rachid Yazami5:
Experimental / 5.1:
The ETMS / 5.2.1:
Electrochemical Cells: Construction and Formation Cycles / 5.2.2:
Thermodynamics Data Acquisition / 5.2.3:
Results / 5.3:
Carbonaceous Anode Materials / 5.3.1:
Pre-coke (HTT < 500 C) / 5.3.1.1:
Cokes HTT 900-1700°C / 5.3.1.2:
Cokes HTT 2200 and 2600°C / 5.3.1.3:
Natural Graphite / 5.3.1.4:
Entropy and Degree of Graphitization / 5.3.1.5:
Cathode Materials / 5.3.2:
LiCoO2 / 5.3.2.1:
LiMn2O4 / 5.3.2.2:
Effect of Cycling on Thermodynamics / 5.3.2.3:
Raman Investigation of Cathode Materials for Lithium Batteries / Rita Baddour-Hadjean ; Jean-Pierre Pereira-Ramos5.4:
Raman Microspectrometry: Principle and Instrumentation / 6.1:
Principle / 6.2.1:
Instrumentation / 6.2.2:
Transition Metal-Oxide-Based Compounds / 6.3:
LiNiO2 and Its Derivative Compounds LiNi1-yCoyO2 (0 < y < 1) / 6.3.1:
Manganese Oxide-Based Compounds / 6.3.3:
MnO2-Type Compounds / 6.3.3.1:
Ternary Lithiated LixMnOy Compounds / 6.3.3.2:
V2O5 / 6.3.4:
V2O5 Structure / 6.3.4.1:
Structural Features of the LixV2O5 Phases / 6.3.4.2:
Titanium Dioxide / 6.3.5:
Phospho-Olivine LiMPO4 Compounds / 6.4:
General Conclusion / 6.5:
Development of Lithium-Ion Batteries: From the Viewpoint of Importance of the Electrolytes / Masaki Yoshio ; Hiroyoshi Nakamura ; Nikolay Dimov7:
General Design to Find Additives for Improving the Performance of LIB / 7.1:
A Series of Developing Processes to Find Novel Additives / 7.3:
Cathodic and the Other Additives for LIBs / 7.4:
Conditioning / 7.5:
Inorganic Additives and Electrode Interface / Shinichi Komaba8:
Transition Metal Ions and Cathode Dissolution / 8.1:
Mn(II) Ion / 8.2.1:
Co(II) Ion / 8.2.2:
Ni(II) Ion / 8.2.3:
How to Suppress the Mn(II) Degradation / 8.3:
LiI, LiBr, and NH4I / 8.3.1:
2-Vinylpyridine / 8.3.2:
Alkali Metal Ions / 8.4:
Na+ Ion / 8.4.1:
K+ Ion / 8.4.2:
Alkali Salt Coating / 8.5:
Characterization of Solid Polymer Electrolytes and Fabrication of all Solid-State Lithium Polymer Secondary Batteries / Masataka Wakihara ; Masanobu Nakayama ; Yuki Kato8.6:
Molecular Design and Characterization of Polymer Electrolytes with Li Salts / 9.1:
Solid Polymer Electrolytes with Plasticizers / 9.1.1:
Preparation of SPE Films with B-PEG and Al-PEG Plasticizers / 9.1.3:
Evaluation of SPE Films with B-PEG Plasticizers / 9.1.4:
Ionic Conductivity of SPE Films with B-PEG Plasticizers / 9.1.5:
Transport Number of Lithium Ions / 9.1.6:
Electrochemical Stability / 9.1.7:
Fabrication of All-Solid-State Lithium Polymer Battery / 9.1.8:
Required Ionic Conductivity of SPE / 9.2.1:
Difference between Conventional Battery with Liquid Electrolyte and All-Solid-State LPB / 9.2.3:
Fabrication and Electrochemical Performance of LPBs Using SPE with B-PEG and/or Al-PEG Plasticizers / 9.2.4:
Fabrication of a Nonflammable Lithium Polymer Battery and Its Electrochemical Evaluation / 9.2.5:
Thin-Film Metal-Oxide Electrodes for Lithium Microbatteries / 9.2.6:
Lithium Cobalt Oxide Thin Films / 10.1:
Sputtered LiCoO2 Films / 10.2.1:
Liquid Electrolyte / 10.2.1.1:
Solid-State Electrolyte / 10.2.1.2:
PLD LiCoO2 Films / 10.2.2:
CVD LiCoO2 Films / 10.2.3:
LiCoO2 Films Prepared by Chemical Routes / 10.2.4:
LiNiO2 and Its Derivatives Compounds LiNi1-xMO2 / 10.2.5:
Li - Ni - Mn Films / 10.3.1:
LiMn2O4 Films / 10.3.4:
Sputtered LiMn2O4 Films / 10.4.1:
PLD LiMn2O4 Films / 10.4.2:
ESD LiMn2O4 Films / 10.4.3:
LiMn2O4 Films Prepared Through Chemical Routes / 10.4.4:
Substituted LiMn2-xMxO4 Spinel Films / 10.4.5:
V2O5 Thin Films / 10.4.6:
Sputtered V2O5 Thin Films / 10.5.1:
PLD V2O5 Thin Films / 10.5.1.1:
CVD V2O5 Films / 10.5.3:
V2O5 Films Prepared by Evaporation Techniques / 10.5.4:
V2O5 Films Prepared by Electrostatic Spray Deposition / 10.5.5:
V2O5 Films Prepared via Solution Techniques / 10.5.6:
MoO3 Thin Films / 10.5.7:
Solid State Electrolyte / 10.6.1:
General Conclusions / 10.6.3:
Research and Development Work on Advanced Lithium-Ion Batteries for High-Performance Environmental Vehicles / Hideaki Horie11:
Energy Needed to Power an EV / 11.1:
Quest for a High-Power Characteristic in Lithium-Ion Batteries / 11.3:
Cell Thermal Behavior and Cell System Stability / 11.4:
Further Reading
Index
Preface
List of Contributors
General Concepts / Kenzo Matsuki ; Kazunori Ozawa1:
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Kharton, Vladislav V. Kharton
出版情報: Wiley Online Library Online Books , 2009
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Preface
Fundamentals, Applications And Perspectives Of Solid State Electrochemistry -
A Synopsis
Solid vs. Liquid State
Thermodynamics and Kinetics of Charge Carriers
Usefulness of Electrochemical Cells
Materials Research Strategies: Bulk Defect Chemistry
Materials Research Strategy: Boundary Defect Chemistry
Nanoionics
Superionic Materials: Structural Aspects
Techniques
Families of Superionic Conductors
Current Status and Future Prospects
Defect Equilibria In Solids And Related Properties: An Introduction
Defect Structure of Solids: Thermodynamic Approach
Basic Relationships between the Defect Equilibria and Charge Tranfer in Solids
Examples of Functional Materials with Different Defect Structures
Ion-Conducting Nanocrystals: Theory, Methods And Applications
Theoretical Aspects
Applications and Perspectives
Experimental Methods
Review of the Current Experimental Data and their Agreement with Theory
Overview and Areas for Future Development
The Fundamentals And Advances Of Solid State Electrochemistry: Intercalation (Insertion) And Deintercalataion (Extraction) In Solid State Electrodes
Thermodynamics of Intercalation and Deintercalation
Kinetics of Intercalation and Deintercalation
Methodological Overview
Solid State Electrochemical Reactions Of Electroactive Micro- And Nanoparticles In A Liquid Electrolyte Environment
Methodological Aspects
Theory
Examples and Applications
Alkali Metal Cation And Proton Conductors: Relationships Between Composition, Crystal Structure And Properties
Principles of Classification and General Comments
Crystal-Chemistry Factors Affecting Cationic Conductivity
Crystal Structural Screening and Studies of the Conduction Paths
Conductors with Large Alkaline Ions
Lithium Ion Conductors
Proton Conductors
Conducting Solids: In The Search For Multivalent Cation Transport
Analysis of Trivalent Cation Transport
Search for Tetravalent Cation Conductors
Oxygen Ion-Conducting Materials
Oxygen Ionic Transport in Acceptor-Doped Oxide Phases: Relevant Trends
Stabilized Zirconia Electrolytes
Doped Ceria
Anion Conductors Based on Bi2O3
Transport Properties of Other Fluorite-Related Phases: Selected Examples
Perovskite-Type LnBO3 (B=Ga,, Al, In, Sc, Y) and their Derivatives
Perovskite-Related Mixed Conductors: A Short Overview
La2Mo2O9-Based Electrolytes
Solid Electrolytes with Apatite Structure
Polymer And Hybrid Materials, Their Electrochemistry And Applications
Introduction
Fundamentals
Fluorinated Ionomer Membranes
Non-Fluorinated Ionomer Membranes
High Temperature PEMs
Conclusion
Electronically Conducting Polymers
Solid Organic and Inorganic Electrochemically Active Materials for Galvanic Cells Operating at Moderate Temperatures
General Features of Doping-Induced Changes in Pi-Conjugated Polymers
High-Temperature Applications Of Solid Electrolytes: Gas Analysis, Pumping And Conversion
Characteristics of a Current-Carrying Electrode on an Oxide Electrolyte
Operating Modes
Cell Materials
Cell Designs
Examples of Applications
Electrochemical Sensors: Fundamentals, Key Materials And Applications
Operation Principles
Materials Challenges
Applications
Preface
Fundamentals, Applications And Perspectives Of Solid State Electrochemistry -
A Synopsis
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Antonio Facchetti, Antonio Facchetti, Tobin J. Marks
出版情報: Wiley Online Library Online Books , Chichester : John Wiley & Sons, Inc., 2009
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Preface
List of Contributors
Combining optical transparency with electrical conductivity: challenges and prospects / Julia Medvedeva1:
Introduction / 1.1:
Electronic Properties of Conventional TCO Hosts / 1.2:
Carrier Generation in Conventional TCO Hosts / 1.3:
Magnetically Mediated TCO / 1.4:
Multicomponent TCO Hosts / 1.5:
Electronic Properties of Light Metal Oxides / 1.6:
Carrier Delocalization in Complex Oxides / 1.7:
An Outlook: Toward an Ideal TCO / 1.8:
References
Transparent Oxide Semiconductors: fundamentals and recent progress / Hideo Hosono2:
Electronic structure in oxides: carrier transport paths in semiconductors / 2.1:
Materials design of p-type TOSs[23,26] / 2.3:
Layered oxychalcogenides: improved p-type conduction and room-temperature stable excitons [26,32,33] / 2.4:
Nano-porous crystal, C12A7: new functions created by subnanometre cages and clathrated anions [39,40] / 2.5:
Transparent amorphous oxide semiconductors (TAOS) and their TFT applications / 2.6:
Perspective / 2.7:
p-Type Wide-Band-Gap Semiconductors for Transparent Electronics / Janet Tate ; Douglas A. Keszler3:
Applications / 3.1:
Challenges Associated with p-Type Wide-Gap Semiconductors / 3.3:
Materials / 3.4:
Outlook and Prospects / 3.5:
Lead Oxide, Synthesis and Applications / Dale L. Perry4:
Overview of synthetic methods and approaches / 4.1:
Synthesis of lead oxides / 4.3:
Applications of lead oxides / 4.4:
Summary / 4.5:
Acknowledgments
Deposition and Performance Challenges of Transparent Conductive Oxides (TCO) on Plastic Substrates / Clark I. Bright5:
Challenges with Plastic Substrate / 5.1:
TCO Performance Comparison - Glass Versus Plastics Substrates / 5.3:
Conductivity Mechanisms in TCO / 5.4:
Qualitative TCO Doping Model / 5.5:
Industrial TCO Deposition Methods on Plastic Substrates / 5.6:
Developing a TCO Deposition Process / 5.7:
Controlling TCO E/O Properties / 5.8:
TSO for Transparent Oxide Electronics / 5.9:
p-Type TCO and TSO / 5.10:
Chapter Key Points and Summary / 5.11:
Oxide semiconductors: from materials to devices / Elvira Fortunato ; Pedro Barquinha ; Gonçalo Gonçalves ; Luís Pereira ; Rodrigo Martins6:
Historical background: From FETs to TFTs / 6.1:
Transparent oxide semiconductors / 6.3:
Emerging devices based on cellulose paper: paper FETs / 6.4:
Conclusions and outlook / 6.5:
Acknowledgements / 6.6:
Carbon Nanotube Transparent Electrodes / Teresa M. Barnes ; Jeffrey L. Blackburn7:
Chirality and Band Structure of SWCNTs / 7.1:
Synthesis, Purification, and Dispersion of SWCNTs / 7.3:
Deposition of SWCNT Networks / 7.4:
Effects of Chemical Doping / 7.5:
Optical Properties of SWCNTs and SWCNT Networks / 7.6:
Electrical Properties of SWCNT Networks / 7.7:
Sheet Resistance and Transport Measurements / 7.8:
Morphology of SWCNT Networks / 7.9:
Literature Results on Transparent SWCNT Networks / 7.10:
Conclusions / 7.11:
Application of transparent amorphous oxide TFT to electronic paper / Manabu Ito8:
Microencapsulated Electrophoretic Display / 8.1:
Flexible Electronic Paper / 8.3:
Application of Transparent Electronics / 8.4:
Conclusion / 8.5:
Solution-processed electronics based on transparent conductive oxides / Vivek Subramanian9:
The case for printed electronics / 9.1:
The case for solution-processed transparent conductive oxides / 9.3:
Transparent Metal Oxide Nanowire Electronics / Rocío Ponce Ortiz ; Antonio Facchetti ; Tobin J. Marks10:
Nanowire Transistors / 10.1:
Transparent Nanowire Circuits and Displays / 10.3:
Application of transparent oxide semiconductors for flexible electronics / Peter F. Carcia10.4:
Zinc Oxide / 11.1:
Indium Oxide / 11.3:
SnO2 thin film transistors / 11.4:
Gate Dielectrics / 11.5:
Transistors on plastic substrates / 11.6:
Patterning / 11.7:
Transparent OLED Displays / Thomas Riedl11.8:
Transparent OLEDs / 12.1:
Transparent Thin Film Transistors / 12.3:
Transparent Active Matrix OLED Displays / 12.4:
Oxide-Based Electrochromics / Claes G. Granqvist12.5:
Transparent solar cells based on organic polymers / Jinsong Huang ; Gang Li ; Walker Li ; Raymond Chen ; Yang Yang14:
Organic Electro-Optic Modulators with Substantially Enhanced Performance based on Transparent Electrodes / Fei Yi ; Seng-Tiong Ho ; Tobin Marks15:
Naphthalenetetracarboxylic Dimides as Transparent Organic Semiconductors / Kevin Cua See ; Howard E. Katz16:
Transparent metal oxide semiconductors as gas sensors / Camilla Baratto ; Elisabetta Comini ; Guido Faglia ; Matteo Ferroni ; Andrea Ponzoni ; Alberto Vomiero ; Giorgio Sberveglieri17:
Index
Electrochromic Devices / Gonalo Gonalves ; Lus Pereira ; Roco Ponce Ortiz13.1:
Some Recent Research Results / 13.3:
Summary and Concluding Remarks / 13.4:
Transparent Solar Cells Based on Organic Polymers / Juo-Hao Li ; Li-Min Chen
Multiple Metal Layer Structure as Transparent Cathode / 14.1:
Transparent Metal Oxide for Anode of High Performance Transparent Solar Cell / 14.3:
Transparent Solar Cell Fabricated by Lamination / 14.4:
Conclusion and Remarks / 14.5:
Organic Electro-Optic Modulators with Substantially Enhanced Performance Based on Transparent Electrodes
TC-Based Low-Voltage, High-Speed Organic EO Modulators / 15.1:
Full Design: A Detailed Example of High-Frequency Modulator Design / 15.3:
Experimental Realization of a TC-Based Organic EO Modulator and Measurement Result / 15.4:
Naphthalenetetracarboxylic Diimides as Transparent Organic Semiconductors
Initial Demonstration of NTCDI Semiconductor FETs / 16.1:
Further Structural Elaboration of NTCDI Molecular Semiconductors / 16.3:
Use of NTCDI Semiconductors in Multifunctional Transistors / 16.4:
Transparent Metal Oxide Semiconductors as Gas Sensors / 16.5:
Sensing with Nanostructures / 17.1:
Synthesis of Nanostructures for Sensing / 17.3:
Gas Sensing with Nanowires / 17.4:
Chemoresistive Sensing Properties of In2O3 Nanowires / 17.5:
Preface
List of Contributors
Combining optical transparency with electrical conductivity: challenges and prospects / Julia Medvedeva1:
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David J. Willock
出版情報: Wiley Online Library Online Books , 2009
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Preface
Symmetry Elements and Operations / 1:
Introduction / 1.1:
The Plane of Symmetry: ? / 1.2:
The Inversion Centre: i / 1.2.3:
Examples of the Impact of Geometric Symmetry on Chemistry / 1.3:
Oxygen Transfer via Metal Porphyrins / 1.3.1:
Nuclear Magnetic Resonance: Chemical Equivalence / 1.3.2:
Summary / 1.4:
Self-Test Questions / 1.5:
Further Reading
More Symmetry Operations and Products of Operations / 2:
Background to Point Groups / 2.1:
Closed Groups and New Operations / 2.3:
Products of Operations / 2.3.1:
Fixed Symmetry Elements / 2.3.2:
Equivalences for Improper Rotation Operations / 2.3.3:
Properties of Symmetry Operations / 2.4:
Equivalent Operations and Equivalent Atoms / 2.4.1:
The Inverse of an Operation / 2.4.2:
The Order of the Product; Operations that Commute / 2.4.3:
Chirality and Symmetry / 2.5:
Completed Multiplication Tables / 2.6:
The Point Groups Used with Molecules / 2.8:
Molecular Classification Using Symmetry Operations / 3.1:
Constructing Reference Models with Idealized Symmetry / 3.3:
Assigning Point Groups to Molecules / 3.4:
Example Point Group Assignments / 3.11:
Example 1: Conformations of Cyclohexane / 3.11.1:
Example 2: Six-Coordinate Metal Complexes / 3.11.2:
Point Group Representations, Matrices and Basis Sets / 3.12:
Symmetry Representations and Characters / 4.1:
Direct Products / 4.2.1:
Multiplication Tables for Character Representations / 4.3:
Matrices and Symmetry Operations / 4.4:
Diagonal and Off-Diagonal Matrix Elements / 4.5:
The Trace of a Matrix as the Character for an Operation / 4.5.1:
Noninteger Characters / 4.7:
Reducible Representations / 4.7.1:
Classes of Operations / 4.8.1:
Degenerate Irreducible Representations / 4.9.1:
The Labelling of Irreducible Representations / 4.10.1:
Completed Tables / 4.12:
Reducible and Irreducible Representations / 4.14:
Irreducible Representations and Molecular Vibrations / 5.1:
Finding Reducible Representations / 5.3:
Properties of Point Groups and Irreducible Representations / 5.4:
The Reduction Formula / 5.5:
Applying the Reduction Formula / 5.5.1:
Choosing the Basis Set / 5.6:
The d-Orbitals in Common Transition Metal Complex Geometries / 5.7.1:
Linear Molecules: Groups of Infinite Order / 5.8.1:
Applications in Vibrational Spectroscopy / 5.10:
Selection Rules / 6.1:
Infrared Spectroscopy / 6.2.1:
Infrared Absorption and the Greenhouse Gases / 6.2.2:
Raman Spectroscopy / 6.2.3:
Comparison of Infrared and Raman Selection Rules / 6.2.5:
General Approach to Analysing Vibrational Spectroscopy / 6.3:
Example: the C-H Stretch Bands of 1,4-Difluorobenzene / 6.3.1:
Symmetry-Adapted Linear Combinations / 6.4:
Normalization / 6.5:
The Projection Operator Method / 6.6:
Projection Operator Applied to the C-H Stretches of 1,4-Difluorobenzene / 6.6.1:
The Projection Operator and Degenerate Representations / 6.6.2:
Linking Results for Symmetry-Inequivalent Sets of Atoms / 6.7:
Sets of Atoms Differing in Mass or Chemical Bond Strength / 6.7.1:
Additional Examples / 6.8:
The fac and mer Isomers of Transition Metal Complexes / 6.8.1:
Symmetry in Chemical Bonding / 6.9:
Wave Phenomena and Interference / 7.1:
The Born Interpretation of the Wavefunction / 7.1.2:
Bond Energies / 7.2:
The Chemical Bond Energy from Molecular Orbitals / 7.2.1:
The Molecular Orbital Energy / 7.2.3:
Bond Order / 7.2.4:
The Relative Energies of Hydrogen-Like Atomic Orbitals / 7.3:
Radial Behaviour of Atomic Orbitals / 7.3.1:
The Relative Energies of Atomic Orbitals in Different Elements / 7.3.2:
The Relative Energies of Atomic Orbitals from Electronegativity / 7.3.3:
The Molecules Formed by Other Second-Row Elements with Hydrogen / 7.4:
The Second-Row Diatomic Molecules / 7.4.1:
Homonuclear Diatomics / 7.5.1:
Heteronuclear Diatomics of Second-Row Elements / 7.5.2:
More Complex Polyatomic Molecules / 7.6:
Ethene / 7.6.1:
Metal Complexes / 7.7:
Complexes Containing ?-Donor Ligands / 7.7.1:
The Jahn-Teller Effect / 7.7.2:
Complexes Containing Ligand Orbitals of ?-Symmetry / 7.7.3:
Appendices / 7.8:
Assignment of Chiral Centre Handedness using Cahn-Ingold-Prelog Rules / Appendix 1:
Model of a Tetrahedron and the Related Cube / Appendix 3:
Model of an Octahedron / Appendix 4:
Matrices and Determinants / Appendix 5:
Matrices as Representations of Symmetry Operators / A5.1:
Products of Matrices / A5.1.1:
Products of Matrices, Expressed as Summations / A5.1.2:
Matrices for Solving Sets of Linear Equations / A5.2:
The Mathematical Background to Infrared Selection Rules / Appendix 6:
Model Based on Classical Mechanics / A6.1:
Model Based on Quantum Mechanics / A6.2:
Excited Vibrational States / A6.3:
Vibrational Modes for Polyatomic Molecules / A6.4:
Generalization to Arbitrary Transitions / A6.5:
Summary of Selection Rules / A6.6:
The Franck-Condon Principle / Appendix 7:
Classical Treatment of Stokes/Anti-Stokes Absorption / Appendix 8:
The Atomic Orbitals of Hydrogen / Appendix 9:
Choice of Coordinate System / A9.1:
Separation of Variables / A9.2:
The Angular Equation / A9.3:
Physical Interpretation of the Angular Equation Solutions / A9.4:
Angular Momentum / A9.5:
The Radial Equation / A9.6:
The Complete Atomic Orbitals / A9.7:
Expectation Values / A9.8:
Real Combinations to Form the Familiar Atomic Orbitals / A9.9:
Cartesian Forms of the Real Angular Functions / A9.10:
Endnote on Imaginary Numbers / A9.11:
The Origin of Chemical Bonding in H2+ / Appendix 10:
Chemical Bond Formation / A10.1:
The Virial Theorem / A10.2:
The Chemical Bond Formation Energy Based on Rigid Atomic Orbitals / A10.4:
Optimal Radial Decay of Molecular Orbitals / A10.9:
Character Tables / Appendix 11:
Non-Axial Groups / A12.1:
Axial Groups / A12.2:
Cubic Groups / A12.2.1:
Groups for Linear Molecules / A12.3.1:
Index
The Nonaxial Groups: Cs,Ci,C1
The Cyclic Groups: Cn, Sn
Axial Groups Containing Mirror Planes: Cnh and Cnv
Examples of Axial Groups Containing Mirror Planes: Cnh and Cnv
Axial Groups with Multiple Rotation Axes: Dn, Dnd and Dnh
Special Groups for Linear Molecules: Cv and Dh
The Cubic Groups: Td and Oh
A Complete Set of Vibrational Modes for H2O
The Projector Operator Method
H2O Models for Identifying the Results of Symmetry Operation Products
The Origin of Chemical Bonding in H+2
H2O Molecular Orbital Calculation in C2v Symmetry
Preface
Symmetry Elements and Operations / 1:
Introduction / 1.1:
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Bikramjit Basu, Dhirendra Katti, Dhirendra S. Katti, Ashok Kumar
出版情報: Wiley Online Library Online Books , Hoboken : John Wiley & Sons, Inc., 2009
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Foreword / Larry L. Hench
Preface
Contributors
About the Editors
Fundamentals of Biomaterials and Biocompatibility / Bikramjit Basu ; Shekhar NathSection I:
Fundamentals of Hydroxyapatite and Related Calcium Phosphates / Racquel Zapanta LeGeros ; Atsuo Ito ; Kunio Ishikawa ; Toshiro Sakae ; John P. LeGeros2:
Materials for Orthopedic Applications / 3:
The Micro Macroporous Biphasic Calcium Phosphate Concept for Bone Reconstruction and Tissue Engineering / Guy Daculsi ; Franck Jegoux ; Pierre Layrolle4:
Science and Technology Integrated Titanium Dental Implant Systems / Yoshiki Oshida ; Elif Bahar Tuna5:
Injectable Hydrogels as Biomaterials / Lakshmi S. Nair ; Cato T. Laurencin ; Mayank Tandon6:
Nanomaterials for Improved Orthopedic and Bone Tissue Engineering Applications / Lijie Zhang ; Sirinrath Sirivisoot ; Ganesh Balasundaram ; Thomas J. Webster7:
Introduction To Processing of Biomaterials / Dhirendra S. Katti ; Shaunak Pandya ; Meghali Bora ; Rakesh MahidaSection II:
Laser Processing of Orthopedic Biomaterials / Rajarshi Banerjee ; Soumya Nag9:
Functionally Graded All Ceramic Hip Joint / Omer Van der Biest ; Guy Anné ; Kim Vanmeensel ; Jef Vleugels10:
Medical Devices Based On Bioinspired Ceramics / Pío González ; Julián Martínez-Fernández ; Antonio R. De Arellano-López ; Mrityunjay Singh11:
Ionomer Glasses: Design and Characterization / Artemis Stamboulis ; Fei Wang12:
Designing Nanofibrous Scaffolds for Tissue Engineering / Neha Arya ; Poonam Sharma13:
Design of Supermacroporous Biomaterials Via Gelation At Subzero Temperatures-Cryogelation / Fatima M. Plieva ; Ashok Kumar ; Igor Yu ; Galaev ; Bo Mattiasson14:
Biomaterial Applications / Akshay Srivastava ; Era JainSection III:
Cell-Based Nanocomposites and Biomolecules for Bone Tissue Engineering / Michelle Ngiam ; Susan Liao ; Casey Chan ; S. Ramakrishna16:
Orthopedic Interface Tissue Engineering: Building The Bridge to Integrated Musculoskeletal Tissue Systems / Helen H. Lu ; Kristen L. Moffat ; Jeffrey P. Spalazzi17:
Cells of The Nervous System and Electrical Stimulation / Carols Atico Ariza ; Surya K. Mallapragada18:
Placental Umbilical Cord Blood: A True Blood Substitute / Niranjan Bhattacharya19:
Supported Cell Mimetic Monolayers and Their Blood Compatibility / K. Kaladhar ; Chandra P. Sharma20:
Titanium Nitride and Diamond Like Carbon Coatings for Cardiovascular Applications / C.V. Muraleedharan ; G.S. Bhuvaneshwar21:
Index
Foreword / Larry L. Hench
Preface
Contributors
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Association for Computing Machinery-Digital Library.
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90.

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Tomas Skopal, Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
出版情報: ACM Digital Library Proceedings , IEEE, 2009
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Kazutoshi Wakabayashi, Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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Association for Computing Machinery-Digital Library.
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