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1.

図書

図書
Isaac S. Kohane, Alvin T. Kho, and Atul J. Butte
出版情報: Cambridge, Mass. ; London : MIT Press, c2003  xviii, 306 p ; 24 cm
シリーズ名: Computational molecular biology
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目次情報: 続きを見る
Foreword
Preface
Acknowledgments
Introduction / 1:
The Future Is So Bright... / 1.1:
Functional Genomics / 1.2:
Informatics and advances in enabling technology / 1.2.1:
Why do we need new techniques? / 1.2.2:
Missing the Forest for the Dendrograms / 1.3:
Sociology of a functional genomics pipeline / 1.3.1:
Functional Genomics, Not Genetics / 1.4:
In silico analysis will never substitute for in vitro and in vivo / 1.4.1:
Basic Biology / 1.5:
Biological caveats in mRNA measurements / 1.5.1:
Sequence-level genomics / 1.5.2:
Proteomics / 1.5.3:
Experimental Design / 2:
The Safe Conception of a Functional Genomic Experiment / 2.1:
Experiment design space / 2.1.1:
Expression space / 2.1.2:
Exercising the expression space / 2.1.3:
Discarding data and low-hanging fruit / 2.1.4:
Gene-Clustering Dogma / 2.2:
Supervised versus unsupervised learning / 2.2.1:
Figure of merit: The elusive gold standard in functional genomics / 2.2.2:
Microarray Measurements to Analyses / 3:
Generic Features of Microarray Technologies / 3.1:
Robotically spotted microarrays / 3.1.1:
Oligonucleotide microarrays / 3.1.2:
Replicate Experiments, Reproducibility, and Noise / 3.2:
What is a replicate experiment? A reproducible experimental outcome? / 3.2.1:
Reproducibility across repeated microarray experiments: Absolute expression level and fold difference / 3.2.2:
Cross-platform (technology) reproducibility / 3.2.3:
Pooling sample probes and PCR for replicate experiments / 3.2.4:
What is noise? / 3.2.5:
Sources and examples of noise in the generic microarray experiment / 3.2.6:
Biological variation as noise: The Human Genome Project and irreproducibility of expression measurements / 3.2.7:
Managing noise / 3.2.8:
Prototypical Objectives and Questions / 3.3:
Two examples: Inter-array and intra-array / 3.3.1:
Preprocessing: Filters and Normalization / 3.4:
Normalization / 3.4.1:
Background on Fold / 3.5:
Fold calculation and significance / 3.5.1:
Fold change may not mean the same thing in different expression measurement technologies / 3.5.2:
Dissimilarity and Similarity Measures / 3.6:
Linear correlation / 3.6.1:
Entropy and mutual information / 3.6.2:
Dynamics / 3.6.3:
Genomic Data-Mining Techniques / 4:
What Can Be Clustered in Functional Genomics? / 4.1:
What Does it Mean to Cluster? / 4.3:
Hierarchy of Bioinformatics Algorithms / 4.4:
Data Reduction and Filtering / 4.5:
Variation filter / 4.5.1:
Low entropy filter / 4.5.2:
Minimum expression level filter / 4.5.3:
Target ambiguity filter / 4.5.4:
Self-Organizing Maps / 4.6:
K-means clustering / 4.6.1:
Finding Genes That Split Sets / 4.7:
Phylogenetic-Type Trees / 4.8:
Two-dimensional dendrograms / 4.8.1:
Relevance Networks / 4.9:
Other Methods / 4.10:
Which Technique Should I Use? / 4.11:
Determining the Significance of Findings / 4.12:
Permutation testing / 4.12.1:
Testing and training sets / 4.12.2:
Performance metrics / 4.12.3:
Receiver operating characteristic curves / 4.12.4:
Genetic Networks / 4.13:
What is a genetic network? / 4.13.1:
Reverse-engineering and modeling a genetic network using limited data / 4.13.2:
Bayesian networks for functional genomics / 4.13.3:
Bio-Ontologies, Data Models, Nomenclature / 5:
Ontologies / 5.1:
Bio-ontology projects / 5.1.1:
Advanced knowledge representation systems for bio-ontology / 5.1.2:
Expressivity versus Computability / 5.2:
Ontology versus Data Model versus Nomenclature / 5.3:
Exploiting the explicit and implicit ontologies of the biomedical literature / 5.3.1:
Data Model Introduction / 5.4:
Nomenclature / 5.5:
The unique gene identifier / 5.5.1:
Postanalysis Challenges / 5.6:
Linking to downstream biological validation / 5.6.1:
Problems in determining the results / 5.6.2:
From Functional Genomics to Clinical Relevance / 6:
Electronic Medical Records / 6.1:
Standardized Vocabularies for Clinical Phenotypes / 6.2:
Privacy of Clinical Data / 6.3:
Anonymization / 6.3.1:
Privacy rules / 6.3.2:
Costs of Clinical Data Acquisition / 6.4:
The Near Future / 7:
New Methods for Gene Expression Profiling / 7.1:
Electronic positioning of molecules: Nanogen / 7.1.1:
Ink-jet spotting of arrays: Agilent / 7.1.2:
Coded microbeads bound to oligonucleotides: Illumina / 7.1.3:
Serial Analysis of Gene Expression (SAGE) / 7.1.4:
Parallel signature sequencing on microbead arrays: Lynx / 7.1.5:
Gel pad technology: Motorola / 7.1.6:
Respecting the Older Generation / 7.2:
The generation gap / 7.2.1:
Separating the wheat from the chaff / 7.2.2:
A persistent problem / 7.2.3:
Selecting Software / 7.3:
Investing in the Future of the Genomic Enterprise / 7.4:
Glossary
Foreword
Preface
Acknowledgments
2.

図書

図書
林典夫, 廣野治子編集
出版情報: 東京 : 南江堂, 2003.2  xi, 391p ; 26cm
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3.

図書

図書
田中ナルミ, 阿部忠光著
出版情報: 東京 : ソフトバンクパブリッシング, 2003.2  xvi, 402p ; 24cm
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4.

図書

図書
池田玲子[ほか]著
出版情報: 東京 : 丸善, 2003.2  xii, 286p ; 26cm
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5.

図書

図書
北山俊哉, 真渕勝, 久米郁男著
出版情報: 東京 : 有斐閣, 2003.2  xiv, 245p ; 19cm
シリーズ名: 有斐閣アルマ ; Interest
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6.

図書

図書
Shahar Mendelson, Alexander J. Smola (eds.)
出版情報: Berlin ; Tokyo : Springer, c2003  257 p. ; 24 cm
シリーズ名: Lecture notes in computer science ; 2600 . Lecture notes in artificial intelligence
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7.

図書

図書
Ivan Dimov ... [et al.] (eds.)
出版情報: Berlin ; Tokyo : Springer, c2003  xii, 574 p. ; 24 cm
シリーズ名: Lecture notes in computer science ; 2542
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8.

図書

図書
Hakan Erdogmus, Tao Weng (eds.)
出版情報: Berlin ; Tokyo : Springer, c2003  xviii, 260 p. ; 24 cm
シリーズ名: Lecture notes in computer science ; 2580
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目次情報: 続きを見る
Protective Wrapper Development: A Case Study / Tom Anderson ; Mei Feng ; Steve Riddle ; Alexander Romanovsky
Establishing Trust in COTS Components / Adnan Bader ; Christine Mingins ; David Bennett ; Sita Ramakrishan
Incorporation of Test Functionality into Software Components / Franck Barbier ; Nicolas Belloir ; Jean-Michel Bruel
Not All CBS Are Created Equally: COTS-Intensive Project Types / Barry W. Boehm ; Dan Port ; Ye Yang ; Jesal Bhuta
Defining a Quality Model for Mail Servers / Juan Pablo Carvallo ; Xavier Franch ; Carme Quer
Classifying Interoperability Conflicts / L. Davis ; D. Flagg ; R. Gamble ; C. Karatas
COTS Software Quality Evaluation / Ljerka Beus-Dukic ; Jørgen Bøegh
Modelling Component Dependencies to Inform Their Selection / N.A.M. Maiden
The Space Shuttle and GPS: A Safety-Critical Navigation Upgrade / John L. Goodman
A Model for Recording Early-Stage Proposals and Decisions on Using COTS Components in Architecture / Tuomas Ihme
Designing Secure Integration Architectures / G. Jonsdottir
Coordination in COTS-Based Development / Moshe Krieger ; Mark Vigder ; John C. Dean ; Muddassir Siddiqui
COTS Integration in Safety Critical Systems Using RTCA/DO-178B Guidelines / Burke Maxey
Techniques for Embedding Executable Specifications in Software Component Interfaces / Ross McKegney ; Terry Shepard
eCots Platform: An Inter-industrial Initiative for COTS-Related Information Sharing / Jean-Christophe Mielnik ; Bernard Lang ; Stephane Lauriere ; Jean-Georges Schlosser ; Vincent Bouthors
COTS-Based Development: Taking the Pulse of a Project / Ed Morris ; Cecilia Albert ; Lisa Brownsword
Estimating the Cost of Security for COTS Software / Donald J. Reifer ; Murali Gangadharan
Bringing COTS Information Technology into Small Manufacturing Enterprises / John Robert ; Charles Buhman ; Suzanne Garcia ; David Allinder
COTS Acquisition Evaluation Process: The Preacher's Practice / Vijay Sai
BiCom: An Evaluation Framework for COTS Components / Fadrian Sudaman
Assessment of Reusable COTS Attributes / Marco Torchiano, Letizia Jaccheri
Implications of Using the Capability Maturity Model Integration (CMMI © ) for COTS-Based Systems / Barbara Tyson
Evaluating COTS Based Architectures / Toby McClean ; Francis Bordeleau
UML-Based Integration Testing for Component-Based Software / Ye Wu ; Mei-Hwa Chen ; Jeff Offutt
Author Index
Protective Wrapper Development: A Case Study / Tom Anderson ; Mei Feng ; Steve Riddle ; Alexander Romanovsky
Establishing Trust in COTS Components / Adnan Bader ; Christine Mingins ; David Bennett ; Sita Ramakrishan
Incorporation of Test Functionality into Software Components / Franck Barbier ; Nicolas Belloir ; Jean-Michel Bruel
9.

図書

図書
Stan Matwin, Claude Sammut (eds.)
出版情報: Berlin ; Tokyo : Springer, c2003  x, 349 p. ; 24 cm
シリーズ名: Lecture notes in computer science ; 2583 . Lecture notes in artificial intelligence
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10.

図書

図書
Alexander Gelbukh (ed.)
出版情報: Berlin ; Tokyo : Springer, c2003  xv, 648 p. ; 24 cm
シリーズ名: Lecture notes in computer science ; 2588
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