| List of contributors |
| Preface |
| Assessing and utilizing the diagnostic or prognostic power of biomarkers / Part 1： |
| Evidence-based medicine: evaluation of biomarkers / R. Andrew Moore1： |
| Development of biomarkers: the industrial perspective / Andy Bufton2： |
| Statistical approaches to rational biomarker selection / Linda D. Sharples3： |
| Using intelligent systems in clinical decision support / Richard Jones4： |
| Biomarkers of kidney disease and dysfunction / Part 2： |
| Biomarkers in renal disease / Christopher P. Price5： |
| The genetics of renal disease / Jean-Pierre Grunfeld ; Bertrand Knebelmann6： |
| Early markers of nephrotoxicity for environmental and occupational monitoring / Robert G. Price7： |
| The early detection of renal impairment in diabetes mellitus. The case for microalbuminuria and other biomarkers / Carl E. Mogensen8： |
| Biomarkers of bone disease and dysfunction / Part 3： |
| Bone turnover markers in clinical practice / Richard Eastell ; Sheila Hart9： |
| Biomarkers of bone formation / Juha Risteli ; Saila Kauppila ; Arja Jukkola ; Eevastiina Marjoniemi ; Jukka Melkko ; Leila Risteli10： |
| Biochemical markers of bone resorption / Simon P. Robins11： |
| The clinical application of biomarkers in osteoporosis / Patrick Garnero12： |
| Sources of preanalytical variability in the measurement of biochemical markers of bone turnover / Markus J. Seibel13： |
| Genetic approaches to the study of complex diseases: osteoporosis / Andre G. Uitterlinden14： |
| Biomarkers of liver disease and dysfunction / Part 4： |
| Biomarkers of hepatic disease / Michael Oellerich15： |
| The immunogenetics of metabolic liver disease / Peter T. Donaldson16： |
| Toxicogenetic markers of liver dysfunction / J. Michael Tredger17： |
| Prognosis and management of patients with acute liver failure / Fin Stolze Larsen18： |
| Biomarkers in artificial and bioartificial liver support / Robin D. Hughes19： |
| Prognostic markers in liver disease / Martin Burdelski20： |
| Apoptosis: biomarkers and the key role of mitochondria / Kelvin Cain21： |
| Liver regeneration: mechanisms and markers / Nelson Fausto ; Jean Campbell22： |
| Determinants of responses to viruses and self in liver disease / Michael P. Manns ; Petra Obermayer-Straub23： |
| IL-6-type cytokines and signalling in inflammation / Peter C. Heinrich ; Johannes G. Bode ; Lutz Graeve ; Serge Haan ; Astrid Martens ; Gerhard Muller-Newen ; Ariane Nimmesgern ; Fred Schaper ; Jochen Schmitz ; Elmar Siewert24： |
| Biomarkers of gastrointestinal disease and dysfunction / Part 5： |
| Biomarkers in gastrointestinal disease / Humphrey J. F. Hodgson25： |
| Tumour markers in gastrointestinal disease / Anthony J. FitzGerald ; Nicholas A. Wright26： |
| Markers of malabsorption: coeliac disease / H. Julia Ellis ; Jocelyn S. Fraser ; Paul J. Ciclitira27： |
| Biomarkers in toxicology / Part 6： |
| Genomics and biomarkers in toxicology / Jonathan D. Tugwood ; Katherine M. Beckett28： |
| Protein profiling and proteomic databases / Julio E. Celis ; Pavel Gromov ; Morten Ostergarrd ; Hildur Palsdottir ; Irina Gromova29： |
| Biomarkers for evaluating the safety of genetically modified foods / Ad A. C. M. Peijnenburg ; Hubert P. J. M. Noteborn ; Harry A. Kuiper30： |
| Biomarkers of cardiovascular disease and dysfunction / Part 7： |
| The impact of biochemical tests on patient management / Paul O. Collinson31： |
| Cardiac natriuretic peptides in risk assessment of patients with acute myocardial infarction or congestive heart failure / Johannes Mair32： |
| Serum markers of inflammation and cardiovascular risk / Juan Carlos Kaski33： |
| The clinical significance of markers of coagulation in acute coronary syndromes / Lina Badimon ; Antonio Bayes-Genis34： |
| Endothelin: what does it tell us about myocardial and endothelial dysfunction? / John Pernow35： |
| Homocysteine: a reversible risk factor for coronary heart disease / John C. Chambers36： |
| Matrix metalloproteinases and their tissue inhibitors / Peter M. Timms ; Stewart Campbell ; Vinijar Srikanthan37： |
| Biomarkers of neurological disease and dysfunction / Part 8： |
| Biomarkers of neurodegenerative disorders / John M. Land38： |
| Traumatic brain injury: assessment by biochemical serum markers / Tor Ingebrigtsen ; Bertil Romner39： |
| An overview of S-100[beta] as a clinically useful biomarker of brain tissue damage / John Azami ; Basil F. Matta40： |
| Biomarkers in transplantation / Part 9： |
| Monitoring heart and lung transplant patients / Marlene L. Rose41： |
| Monitoring liver transplant recipients / Andrew Trull42： |
| Chronic allograft damage index as a surrogate marker for chronic allograft rejection / Serdar Yilmaz ; Mark Nutley ; Eero Taskinen ; Timo Paavonen ; Pekka Hayry43： |
| Advances in pharmacodynamic biomarkers for monitoring the response to immunosuppressive drug therapy / Victor W. Armstrong44： |
| The use of biomarkers for monitoring the response to immunosuppressive drug therapy / Atholl Johnston45： |
| Post-transplantation bone disease / Juliet E. Compston46： |
| Molecular diagnosis of cytomegalovirus disease / Aycan F. Hassan-Walker ; Vincent C. Emery ; Paul D. Griffiths47： |
| Diagnosis and monitoring of inflammatory events in transplant recipients / Claus Hammer ; Gudrun Hobbel ; Stephanie Hammer ; Peter Fraunberger ; Bruno Meiser48： |
| Index |
| Assessing and Utilising the Diagnostic and Prognostic Power of Biomarkers / Part I： |
| Biomarkers of Kidney Disease and Dysfunction / Part II： |
| Biomarkers of Bone Disease and Dysfunction / Part III： |
| Biomarkers of Liver Disease and Dysfunction / Part IV： |
| Biomarkers of Gastrointestinal Disease and Dysfunction / Part V： |
| Biomarkers in Toxicology / Part VI： |
| Biomarkers of Cardiovascular Disease and Dysfunction / Part VII： |
| Biomarkers of Neurological Disease and Dysfunction / Part VIII： |
| Biomarkers in Transplantation / Part IX： |
| List of contributors |
| Preface |
| Assessing and utilizing the diagnostic or prognostic power of biomarkers / Part 1： |
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