close
1.

図書

図書
edited by Helmut Sies, Lester Packer ; editorial advisory board, Bob Buchanan ... [et al.]
出版情報: San Diego ; Tokyo : Academic Press, c2002  xxxvi, 511 p. ; 24 cm
シリーズ名: Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan ; v. 347 . Protein sensors and reactive oxygen species ; pt. A
所蔵情報: loading…
2.

図書

図書
edited by Helmut Sies, Lester Packer ; editorial advisory board, Bob Buchanan ... [et al.]
出版情報: San Diego ; Tokyo : Academic Press, c2002  xxxiv, 404 p. ; 24 cm
シリーズ名: Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan ; v. 348 . Protein sensors and reactive oxygen species ; pt. B
所蔵情報: loading…
3.

図書

図書
edited by Robert K. Poole
出版情報: Amsterdam ; Tokyo : Elsevier Academic Press, c2008  2 v. ; 24 cm
シリーズ名: Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan ; v. 436-437
所蔵情報: loading…
目次情報: 続きを見る
Nitric Oxide: Chemical and Analytical Methods / Section I:
The Chemistry of Nitric Oxide and Related Species / Martin H. HughesChapter 1:
Delivery of nitric oxide for analysis of the function of cytochrome / c. Lindsay J. Cole ; Wilhelmina M. Huston ; James W.B. MoirChapter 2:
The preparation and purification of NO gas and the use of NO releasers / Chapter 3:
The application of NO donors and other agents of nitrosative stress in biological systems / Rubina G. Aga ; Martin N. Hughes
The Chemistry of Peroxynitrite Implications for Biological Activity / Sara Goldstein ; Gabor Mereacute;nyiChapter 4:
Nitric Oxide (NO) Selective Electrodes / Ian R. Davies ; Xueji ZhangChapter 5:
NO, N2O and O2 Reaction Kinetics: Scope and Limitations of the / Clark Electrode L.A.M. Pouvreau ; M. J. F. Strampraad ; S. Van Berloo ; J. H. Kattenberg ; S. de VriesChapter 6:
Chemiluminescence quantification of Nitric oxide and its derivatives in liquid samples / Jay R. Laver ; Tacirc;nia M. Stevanin ; Robert C. ReadChapter 7:
Bacterial and Archaeal Hemoglobins / Section II:
Interactions of nitric oxide with hemoglobin: from microbes to man / Michael Angelo ; Alfred Hausladen ; Jonathan S. StamlerChapter 8:
Expression and purification of / E. coli Hmp Robert K. PooleChapter 9:
Alberto Boffi / Chapter 10:
Liacute;gia M. Saraiva / Chapter 11:
Paul R. Gardner / Chapter 12:
Alessandra Bonamore / Chapter 13:
Assessment of Biotechnologically Relevant Characteristics of Heterologous Hemoglobins in Escherichia coli / Pauli T. Kallio ; Christian J. T. Bollinger ; Taija Koskenkorva ; Alexander D. FreyChapter 14:
Guo-Qiang CHEN / Chapter 15:
Robert K. Poole / Chapter 16:
Martino Bolognesi / Chapter 17:
Paolo Visca / Chapter 18:
Other Hemoglobins / Section III:
Kirsten Mees / Laurent Coger ; Christophe Lechauve ; Michael C. Marden ; Alexandra Pesce ; Martino Bolognesi ; Luc MoneesChapter 19:
Measurement of distal histidine coordination equilibrium and kinetics in hexacoordinate hemoglobins / Benoit J. Smagghe ; Puspita Halder ; Mark S. HargroveChapter 20:
Purification of Class 1 Plant Hemoglobins and Examination of their Functional Properties / Abir U. Igamberdiev ; Robert D. HillChapter 21:
Use of in silico (computer) methods to predict and analyze the tertiary structure of plant hemoglobins / Sabarinathan Kuttalingam Gopalasubramaniam ; Veroacute;nica Garrocho-Villegas ; Genoveva Bustos Rivera ; Nina Pastor ; Rauacute;l Arredondo-PeterChapter 22:
A Self-induction Method to Produce High Quantities of Recombinant Functional Flavo-Leghemoglobin Reductase / Estibaliz Urarte ; Intilde;igo Auzmendi ; Selene Rol ; Idoia Ariz ; Pedro Aparicio-Tejo ; Jose F. MoranChapter 23:
Spectroscopic and crystallographic characterization of bis-histidyl adducts in tetrameric hemoglobins / Alessandro Vergara ; Luigi VitaglianoChapter 24:
Contributors
Preface
Volumes in Series
Nitric Oxide-Metabolising and Detoxifying Enzymes
Structural Studies on Flavodiiron Proteins / Joao B. Vicente ; Maria Armenia Carrondo ; Miguel Teixeira ; Carlos Frazao1:
Introduction
Crystallization of Flavodiiron Proteins / 2:
Diffraction Data Collection, Structure Determination, and Refinement / 3:
Overall Description of Structures / 4:
Conclusion / 5:
References
Biochemical, Spectroscopic, and Thermodynamic Properties of Flavodiiron Proteins / Marta C. Justino ; Vera L. Goncalves ; Ligia M. Saraiva
Cloning of Genes Encoding Flavodiiron Proteins and Their Truncated Domains
Production and Purification of Recombinant Flavodiiron Proteins
Biochemical Characterization of Flavodiiron Proteins
Spectroscopic Properties
Redox Properties / 6:
Conclusions / 7:
Acknowledgments
Kinetic Characterization of the Escherichia coli Nitric Oxide Reductase Flavorubredoxin / Francesca M. Scandurra ; Elena Forte ; Maurizio Brunori ; Paolo Sarti ; Alessandro Giuffre
Amperometric Measurements
Spectroscopic Measurements
Escherichia coli Cytochrome c Nitrite Reductase NrfA / Thomas A. Clarke ; Paul C. Mills ; Susie R. Poock ; Julea N. Butt ; Myles R. Cheesman ; Jeffrey A. Cole ; Jay C. D. Hinton ; Andrew M. Hemmings ; Gemma Kemp ; Christopher A. G. Soderberg ; Stephen Spiro|cJessica Van Wonderen ; David J. Richardson
Measurement of Cytochrome c Nitrite Reductase-Dependent Consumption of Nitric Oxide in Whole Cells
Growth of E. coli Optimized for Cytochrome c Nitrite Reductase Production for Use in Enzyme Purification
Purification of Cytochrome c Nitrite Reductase
Assaying the Cytochrome c Nitrite Reductase
Crystallization of E. coli Cytochrome c Nitrite Reductase
Concluding Remarks
The Respiratory Nitric Oxide Reductase (NorBC) from Paracoccus denitrificans / Sarah J. Field ; Faye H. Thorndycroft ; Andrey D. Matorin ; Nicholas J. Watmough
Purification of Native NorBC from Paracoccus denitrificans
Purification of Recombinant NorBC
Amperometric Assays of NO Consumption
Pseudoazurin as an Electron Donor in Assays of NorBC
Preparation of NOR for Spectroscopic Investigation
Electron Paramagnetic Resonance Spectroscopy
Redox-Controlled Dinitrosyl Formation at the Diiron-Oxo Center of NorA / Rainer Cramm ; Katja Strube8:
Genetic Context and Expression of the NorA Gene in R. eutropha
Purification of NorA
Disulfide Bridges in NorA
Iron Analysis and Preparation of Apo-NorA
Interconversion of Redox Forms of NorA
Generation of NorA-DNIC In Vitro
Preparation of NorA-DNIC Formed In Vivo
Quantification of NO from NorA-DNIC / 9:
Outlook / 10:
Purification and Functional Analysis of Fungal Nitric Oxide Reductase Cytochrome P450nor / Li Zhang ; Hirofumi Shoun
Screening of P450nor Activity
Gas Analysis
Purification of P450nor
Nitric Oxide Reductase Activity Assay
Protein Sequencing
Isolation of cDNA
Subcellular Fractionation of T. cutaneum
Site-Directed Mutagenesis
Expression of Recombinant Proteins
Purification of Recombinant Proteins / 11:
Titration of NAD Analogs / 12:
Stopped-Flow Rapid Scan Analysis / 13:
Other Analysis / 14:
A Quantitative Approach to Nitric Oxide Inhibition of Terminal Oxidases of the Respiratory Chain / Maria G. Mason ; Rebecca S. Holladay ; Peter Nicholls ; Mark Shepherd ; Chris E. Cooper15:
Evaluation of Current Techniques for Measuring pNO, pO[subscript 2], and K[subscript M] (O[subscript 2])
Nitric Oxide Donor Compounds
Nitric Oxide Kinetics
Oxygen Kinetics
Optical Detection of Enzyme Intermediates in the Presence of Oxygen and NO
Appendices
Sensor Proteins
Cloning, Expression, and Purification of the N-terminal Heme-Binding Domain of Globin-Coupled Sensors / Jennifer A. Saito ; Tracey Allen K. Freitas ; Maqsudul Alam
Bioinformatic Search of Globin-Coupled Sensors
Functional Analysis of Globin-Coupled Sensors
Oxygen-Sensing Histidine-Protein Kinases: Assays of Ligand Binding and Turnover of Response-Regulator Substrates / Marie-Alda Gilles-Gonzalez ; Gonzalo Gonzalez ; Eduardo Henrique Silva Sousa ; Jason Tuckerman
Assays
Reactions of Nitric Oxide and Oxygen with the Regulator of Fumarate and Nitrate Reduction, a Global Transcriptional Regulator, during Anaerobic Growth of Escherichia coli / Jason C. Crack ; Nick E. Le Brun ; Andrew J. Thomson ; Jeffrey Green ; Adrian J. Jervis
Production of 4Fe-FNR Protein
Determination of Iron and Acid-Labile Sulfide Content of FNR
UV-Visible Absorbance Spectra of FNR
Cluster Reaction with Nitric Oxide and Oxygen
Purification of 2Fe-FNR
Detection of Other Reaction Products
Genome-Wide Identification of Binding Sites for the Nitric Oxide-Sensitive Transcriptional Regulator NsrR / Sam Efromovich ; David Grainger ; Diane Bodenmiller ; Stephen Spiro
Strain Construction
Reference and Control Samples
Culture Conditions
Immunoprecipitation of DNA Targets Associated with NsrR
DNA Labeling, Microarray Hybridization, and Processing
Visualization and Analysis of DNA Microarray Data
A New Statistical Methodology for Treatment of Chip-on-Chip Data
Characterization of the Nitric Oxide-Reactive Transcriptional Activator NorR / Benoit D'Autreaux ; Nick Tucker ; Ray Dixon
Measurement of NorR Activity In Vivo
Measurement of Transcriptional Activation by NorR In Vitro
Detection of the Ferrous-Nitrosyl Form of NorR by In Vivo Electron Paramagnetic Resonance (EPR)
In Vitro Reconstitution of the Iron Center in NorR
Measurement of NO Affinity
Standardization of the NO Electrode
Determination of NorRFe(NO) K[subscript d]
Acknowledgment
Advanced Spectroscopic Methods
Hemoglobins from Mycobacterium tuberculosis and Campylobacter jejuni: A Comparative Study with Resonance Raman Spectroscopy / Changyuan Lu ; Tsuyoshi Egawa ; Masahiro Mukai ; Robert K. Poole ; Syun-Ru Yeh
Hemoglobin Superfamily: An Overview
Microbial Hemoglobins
Resonance Raman Spectroscopy: Applications in Hemeproteins
Structures and Functions of Microbial Hemoglobins
Closing Remarks
The Power of Using Continuous-Wave and Pulsed Electron Paramagnetic Resonance Methods for the Structure Analysis of Ferric Forms and Nitric Oxide-Ligated Ferrous Forms of Globins / Sabine Van Doorslaer ; Filip Desmet
Electron Paramagnetic Resonance in a Nutshell
EPR Studies of NO-Ligated Globins
EPR Studies of Ferric globins
Spin-Labeling Heme Proteins
Future Challenges and Possibilities
Oxygen Binding to Heme Proteins in Solution, Encapsulated in Silica Gels, and in the Crystalline State / Luca Ronda ; Stefano Bruno ; Serena Faggiano ; Stefano Bettati ; Andrea Mozzarelli16:
Oxygen-Binding Curves to Heme Proteins
Determination of OBCs for Hemoglobin in Solution
Determination of K[subscript 1] for Hemoglobin in Solution in the Absence of Allosteric Effectors
Determination of OBCs for T State Hemoglobin Gels in the Absence and Presence of Allosteric Effectors
Determination of OBCs for T State Hemoglobin Crystals
Determination of OBCs for Hemocyanin in Solution and in Silica Gels
Characterization of Ligand Migration Mechanisms inside Hemoglobins from the Analysis of Geminate Rebinding Kinetics / Stefania Abbruzzetti ; Elena Grandi ; Cristiano Viappiani17:
Principles of Nanosecond Laser Flash Photolysis
Basic Experimental Layouts
Encapsulation of Hbs in Silica Gels
Enhancement of Geminate Rebinding and Advantages of Gel Encapsulation
Extraction of Kinetic Information
Ligand Dynamics in Heme Proteins Observed by Fourier Transform Infrared Spectroscopy at Cryogenic Temperatures / Karin Nienhaus ; G. Ulrich Nienhaus18:
Materials
Fourier Transform Infrared Cryospectroscopy
Low-Temperature FTIR Spectroscopy on NO-Ligated Heme Proteins
Time-Resolved X-Ray Crystallography of Heme Proteins / Vukica Srajer ; William E. Royer, Jr.19:
Experiment
Data Processing and Analysis
A Case Study: Scapharca Dimeric Hemoglobin
Structural Dynamics of Myoglobin / M. Brunori ; D. Bourgeois ; B. Vallone20:
Background
Crystallographic Studies of Myoglobin States
Experimental Approaches
Use of the Conjugate Peak Refinement Algorithm for Identification of Ligand-Binding Pathways in Globins / Stephen D. Golden ; Kenneth W. Olsen21:
Exploration of Oxygen-Binding Pathways in Myoglobin
Theoretical Models
Potential Energy Function
Transition Pathways
Methods
Results
Finding Gas Migration Pathways in Proteins Using Implicit Ligand Sampling / Jordi Cohen ; Klaus Schulten22:
Example Calculation: Truncated Hemoglobin (trHb) from Paramecium caudatum
Discussion
Identification of Ligand-Binding Pathways in Truncated Hemoglobins Using Locally Enhanced Sampling Molecular Dynamics / 23:
Molecular Dynamics
Locally Enhanced Sampling Molecular Dynamics
Nitric Oxide Reactivity with Globins as Investigated Through Computer Simulation / Marcelo A. Marti ; Luciana Capece ; Axel Bidon-Chanal ; Alejandro Crespo ; Victor Guallar ; F. Javier Luque ; Dario A. Estrin24:
Molecular Dynamics (MD) Methods
Quantum Mechanical-Molecular Mechanical Methods
Illustrative Examples
Ligand Migration Profiles from MSMD and PELE Simulations: Exploring Ligand Entry Pathways in M. tuberculosis trHbN
Microbial Responses to Nitric Oxide and Nitrosative Stress: Growth, "Omic," and Physiological Methods / Steven T. Pullan ; Claire E. Monk ; Lucy Lee25:
Nitric Oxide, NO-Releasing Agents, and Nitrosating Agents
Illustrative Results from Applications of These Methods
Analysis of Nitric Oxide-Dependent Antimicrobial Actions in Macrophages and Mice / Andres Vazquez-Torres ; Tania Stevanin ; Jessica Jones-Carson ; Margaret Castor ; Ferric C. Fang26:
NO.-Dependent Antimicrobial Actions of Murine Macrophages
NO.-Dependent Antimicrobial Actions of Human Macrophages
NO.-dependent Antimicrobial Actions in Laboratory Mice
Measuring Nitric Oxide Metabolism in the Pathogen Neisseria meningitidis / Melanie J. Thomson ; Tania M. Stevanin ; James W. B. Moir27:
Safety Aspects of Handling N. meningitidis in the Laboratory
Metabolism of Neisseria sp.
Experimental Approaches to Analyzing Nitrogen Metabolism Relevant to NO
Simultaneous Measurement of Oxygen and NO during Pure Culture of N. meningitidis
Measurement of NO Production/Disappearance in Tissue Culture Using Human Monocyte-Derived Macrophages
Localization of S-Nitrosothiols and Assay of Nitric Oxide Synthase and S-Nitrosoglutathione Reductase Activity in Plants / Francisco J. Corpas ; Alfonso Carreras ; Francisco J. Esteban ; Mounira Chaki ; Raquel Valderrama ; Luis A. Del Rio ; Juan B. Barroso28:
Determination of L-Arginine-Dependent NOS Activity by Ozone Chemiluminescence in Plant Tissues
Assay of GSNOR Activity
Localization of S-Nitrosothiols and S-Nitrosoglutathione in Plant Tissues by Confocal Laser-Scanning Microscopy (CLSM)
Methods for Nitric Oxide Detection during Plant-Pathogen Interactions / E. Vandelle ; M. Delledonne29:
Nitric Oxide Detection by Mass Spectrometry
Nitric Oxide Detection by Laser Photoacoustic Spectroscopy
Nitric Oxide Detection by Chemiluminescence
Nitric Oxide Detection by Hemoglobin Conversion
Nitric Oxide Detection by Electron Paramagnetic Resonance (EPR) Spin Trap
Nitric Oxide Detection Using Diaminofluoresceins
Bioimaging Techniques for Subcellular Localization of Plant Hemoglobins and Measurement of Hemoglobin-Dependent Nitric Oxide Scavenging In Planta / Kim H. Hebelstrup ; Erik Ostergaard-Jensen30:
Measuring Hemoglobin-Dependent NO Scavenging
Techniques for Determination of Subcellular Localization of Plant Hemoglobins
Imaging of Hemoglobin-Dependent NO Scavenging in Arabidopsis Plants
Engineering of GLB1-GFP/GLB2-GFP Constructs and Microscopic Analysis of A. thaliana Plants Expressing GFP-Tagged Hemoglobin
Use of Recombinant Iron-Superoxide Dismutase as A Marker of Nitrative Stress / Estibaliz Larrainzar ; Inigo Auzmendi ; Cesar Arrese-Igor ; Esther M. Gonzalez31:
Immunodetection of Nitrated Proteins: Metal-Mediated Tyrosine Nitration of BSA
Tyrosine Nitration of Purified Recombinant Vu_FeSOD Affects its Enzymatic Activity
Tyrosine Nitration in Vu_FeSOD can be Estimated Using Antibodies Against 3-Nitrotyrosine
SIN-1-Dependent Vu_FeSOD Nitration can be Detected by the Loss of Enzymatic Activity
Author Index
Subject Index
Nitric Oxide: Chemical and Analytical Methods / Section I:
The Chemistry of Nitric Oxide and Related Species / Martin H. HughesChapter 1:
Delivery of nitric oxide for analysis of the function of cytochrome / c. Lindsay J. Cole ; Wilhelmina M. Huston ; James W.B. MoirChapter 2:
4.

図書

図書
edited by Jan Sedzik, Paolo Riccio
出版情報: New Jersey : World Scientific, c2009  xi, 352 p. ; 24 cm
所蔵情報: loading…
目次情報: 続きを見る
Preface
From Kuru to Nucleation, Aggregation, Polymerization and Crystallization in Biology and Medicine / D. Carleton Gajdusek1:
Gels Mimicking Antibodies in Their Selective Recognition of Proteins and Its Potential Use for Protein Crystallization / Jan Sedzik ; Nasim Ghasemzadeh ; Fred Nyberg ; Stellan Hjertén2:
Bioinformatics of Myelin Membrane Proteins / Gunnar von Heijne3:
Biomolecular Mass Spectrometry: Applications to Proteins and Peptides / Leopold L. Ilag ; Gianluca Maddalo4:
Myelin: A One-Dimensional Biological "Crystal" for X-Ray and Neutron Scattering / Hideyo Inouye ; Daniel A. Kirschner5:
Two-Dimensional Crystallization of Biological Macromolecules / Hans Hebert6:
Crystallization of Proteins: Principles and Methods / Lata Govada7:
The Role of Oil in Protein Crystallization / Naomi E. Chayen8:
Introduction to Crystallization of Fine Chemicals and Pharmaceuticals / Ã…ke C. Rasmuson9:
Myelin Basic Protein, A Saucy Molecule With High Responsiveness to the Environment or Just an Unusual Membrane Protein? / Paolo Riccio10:
The Use of a Magnetic Field and Magnetic Force as a Means to Improve the Quality of Protein Crystals / Mitsuo Ataka11:
Interactive Crystallomic / 12:
Virtual Molecule: P0 Myelin Glycoprotein. I. Homology Modeling and Prediction of the Secondary and Tertiary Structure / Jan Pawel Jastrzebski13:
In meso Approaches to Membrane Protein Crystallization / Valentin I. Gordeliy ; Ekaterina S. Moiseeva14:
Amyloid, The Amyloid ?-Peptide and Alzheimer's Disease: Structural Considerations / Lars O. Tjernberg15:
Recent Advances in Structural Basis for Molecular Mimicry in Inflammatory Autoimmune Demyelinating Polyneuropathy / Xin Yang16:
Fresh Water Pearls of Wisdom on Protein Crystallization / 17:
Glossary
Index
Preface
From Kuru to Nucleation, Aggregation, Polymerization and Crystallization in Biology and Medicine / D. Carleton Gajdusek1:
Gels Mimicking Antibodies in Their Selective Recognition of Proteins and Its Potential Use for Protein Crystallization / Jan Sedzik ; Nasim Ghasemzadeh ; Fred Nyberg ; Stellan Hjertén2:
5.

図書

図書
edited by Tom W. Muir, John N. Abelson
出版情報: Amsterdam ; Tokyo : Academic Press, 2009  xliii, 264 p., [8] p. of plates ; 24 cm
シリーズ名: Methods in enzymology / editors in chief, Sidney P. Colowick, Nathan O. Kaplan ; v. 462
所蔵情報: loading…
目次情報: 続きを見る
(Tentative)
Protein Engineering with the Traceless Staudinger Ligation / Ronald T. Raines ; Annie Tam1:
Mechanistic studies of RNR using unnatural amino acids and semisynthesis / Joann Stubbe2:
Using Expressed Protein Ligation to Probe the Substrate Specificity of Lantibiotic Synthetases / Wilfred van der Donk ; Xingang Zhang3:
Protein Phosphorylation by Semisynthesis: From Paper to Practice / Phlip A. Cole,Lawrence M. Szewczuk ; Mary Katherine Tarrant4:
Mechanistic studies of semisynthetic ion channels / Francis Valiyaveetil5:
Semi-synthesis of proteins using split inteins / Henning D. Mootz ; Christina Ludwig ; Joachim Zettler ; Daniel Garbe6:
Segmental Isotopic Labeling of Proteins for Nuclear Magnetic Resonance / David Cowburn ; Dongsheng Liu ; Rong Xu7:
Use of intein-mediated protein ligation strategies for the fabrication of functional protein arrays / Shao Q Yao ; Souvik Chattopadhaya ; Farhana B. Abu Bakar8:
Expressed Protein Ligation for Metalloprotein Design and Engineering / Yi Lu ; Kenneth Clark9:
(Tentative)
Protein Engineering with the Traceless Staudinger Ligation / Ronald T. Raines ; Annie Tam1:
Mechanistic studies of RNR using unnatural amino acids and semisynthesis / Joann Stubbe2:
6.

図書

図書
edited by Andrew B. Hughes
出版情報: Weinheim : Wiley-VCH, c2009  xix, 701 p. ; 25 cm
シリーズ名: Amino acids, peptides and proteins in organic chemistry / edited by Andrew B. Hughes ; v. 1
所蔵情報: loading…
目次情報: 続きを見る
Amino Acid Origins
Primitive Amino Acid Chemistry Extraterrestrial Amino Acids Terrestrial Amino Acids and Their Evolution
The Common alpha-Amino Acids; Proteinogenic Amino Acid Biosynthesis Uncommon alpha-Amino Acid;
Non-Proteinogenic Amino Acid Biosynthesis beta-Amino Acid Biosynthesis
Synthesis Of Amino Acids
Common or Proteinogenic alpha-Amino Acids Fermentation Production of alpha-Amino Acids Radical Synthetic
Methods for alpha-Amino Acids Uncommon or Non-Proteinogenic alpha-Amino Acids Synthesis of Non-Coding
Amino Acids Synthesis of N-Alkyl Amino Acids Synthesis of beta-Amino Acids Synthesis of Alicyclic beta-Amino Acids
Synthesis of alpha,beta-Diamino Acids Synthesis of Halogenated Amino Acids Synthesis of Isotopically Labelled Amino
Acids Synthesis of Unnatural/Non-proteinogenic alpha-Amino Acids Synthesis of gamma- and delta-Amino Acids Synthesis of GABA and Amino Acid-Based
GABA analogues Synthesis and Chemistry of alpha,beta-Dehydroamino Acids Synthesis and Chemistry of Hydrazino Acids Synthesis and Chemistry of Hydroxamic
Acids (N-Hydroxy Amino Acids) Chemistry of Aminoboronic Acids Chemistry of alpha-Aminophosphonic Acids and Phosphonopeptides
Chemistry of alpha-Silyl Amino Acids Use of Enzymes in Synthesis of Amino Acids
Amino Acid Origins
Primitive Amino Acid Chemistry Extraterrestrial Amino Acids Terrestrial Amino Acids and Their Evolution
The Common alpha-Amino Acids; Proteinogenic Amino Acid Biosynthesis Uncommon alpha-Amino Acid;
7.

図書

図書
edited by Andrew B. Hughes
出版情報: Weinheim : Wiley-VCH, c2009  xxii, 683 p. ; 25 cm
シリーズ名: Amino acids, peptides and proteins in organic chemistry / edited by Andrew B. Hughes ; v. 2
所蔵情報: loading…
目次情報: 続きを見る
Amino Acid Organocatalysis
Catalysis of Reactions by Amino Acids
Catalysis of Reactions by Small Peptides
Enzymes
Enzymic Mechanisms of Catalysis
The Chemistry of Proteases
Semi-Synthetic Enzymes
Non-Enzymic Mechanisms of Catalysis
Substrate Recognition
Protein Recognition
Non-Ribosomal Peptide Synthesis
Amino Acid Organocatalysis
Catalysis of Reactions by Amino Acids
Catalysis of Reactions by Small Peptides
8.

図書

図書
edited by Richard H. Templar and Robin Leatherbarrow
出版情報: Cambridge : Royal Society of Chemistry, 2002  ix, 280 p ; 24 cm.
所蔵情報: loading…
目次情報: 続きを見る
Probing Biological Molecules: Theory and Experiment / I:
Flow Oriented Linear Dichroism to Probe Protein Orientation in Membrane Environments / A. Rodger ; J. Rajendra ; R. Mortimer ; T. Andrews ; J.D. Hirst ; A.T.B. Gilbert ; R. Marrington ; T.R. Dafforn ; D.J. Halsall ; M. Ardhammar ; B. Norden ; C.A. Woolhead ; C. Robinson ; T.J.T. Pinheiro ; J. Kazlauskaite ; M. Seymour ; N. Perez ; M.J. Hannon
Quantitative Protein Circular Dichroism Calculations / N.A. Besley
Probing Cellular Structure and Function by Atomic Force Microscopy / M.A. Horton ; P.P. Lehenkari ; G.T. Charras
Physical Characterization of Wild Type and mnn9 Mutant Cells of Saccharomyces cerevisiae by Atomic Force Microscopy (AFM) / A. Mendez-Vilas ; I. Corbacho ; M.L. Gonzalez-Martin ; M.J. Nuevo
Probing Supramolecular Organisation at Immune Synapses / F.E. McCann ; K. Suhling ; L.M. Carlin ; K. Eleme ; K. Yanagi ; P.M.W. French ; D. Phillips ; D.M. Davis
Probing the Structure of Viral Ion Channel Proteins: A Computational Approach / W.B. Fischer ; M.S.P. Sansom
The Impact of H[subscript 2]O[subscript 2] on the Structure of Catalases by Molecular Modelling Methods / S.G. Kalko ; J.Ll. Gelpi ; M. Orozco
Entropy in the Alignment and Dimerization of Class C G-Protein Coupled Receptors / M.K. Dean ; C. Higgs ; R.E. Smith ; P.D. Scott ; R.P. Bywater ; T.J. Howe ; C.A. Reynolds
Electrostatic Stability of Wild Type and Mutant Transthyretin Oligomers / S. Skoulakis ; J.M. Goodfellow
Simulations of Human Lysozyme: Conformations Triggering Amyloidosis in 156T Mutant / G. Moraitakis
Collective Excitation Dynamics in Molecular Aggregates: Exciton Relaxation, Self-Trapping and Polaron Formation / M. Dahlbom ; W. Beenken ; V. Sundstrom ; T. Pullerits
Surprising Electro-magnetic Properties of Close Packed Organized Organic Layers--Magnetization of Chiral Monolayers of Polypeptide / I. Carmeli ; V. Shakalova ; R. Naaman ; Z. Vager
Barrier Crossing by a Flexible Long Chain Molecule--The Kink Mechanism / K.L. Sebastian
Proteins, Lipids and Their Interactions / II:
Lipid Interaction with Cytidylyltransferase Regulates Membrane Synthesis / S. Jackowski ; I. Baburina
Models and Measurements on the Monolayer Bending Energy of Inverse Lyotropic Mesophases / A.M. Squires ; J.M. Seddon ; R.H. Templer
Hemolytic and Antibacterial Activities of LK Peptides of Various Topologies: A Monolayer and PM-IRRAS Approach / S. Castano ; B. Desbat ; H. Wroblewski ; J. Dufourcq
A Novel Approach for Probing Protein--Lipid Interactions of MscL, a Membrane-Tension-Gated Channel / P.C. Moe ; P. Blount
Folding of The [alpha]-Helical Membrane Proteins DsbB and NhaA / D.E. Otzen
FhuA, an Escherichia coli Transporter and Phage Receptor / P. Boulanger ; L. Plancon ; M. Bonhivers ; L. Letellier
Morpholgical Aspects of in cubo Protein Crystallisation / C. Sennoga ; B. Hankamer ; A. Heron ; J. Barber
Mobility of Proteins and Lipids in the Photosynthetic Membranes of Cyanobacteria / C.W. Mullineaux ; M. Sarcina
Partitioning and Thermodynamics of Chlordiazepoxide in n-Octanol/Buffer and Liposome System / C. Rodrigues ; P. Gameiro ; S. Reis ; J.L.F.C. Lima ; B. De Castro
Distribution of Vitamin E in Model Membranes / P.J. Quinn
Theory on Opening-up of Liposomal Membranes by Adsorption of Talin / Y. Suezaki
Differential Scanning Calorimetry and X-Ray Diffraction Studies of Glycolipid Membranes / O. Ces ; D.A. Mannock ; R.N. McElhaney
Subject Index
Probing Biological Molecules: Theory and Experiment / I:
Flow Oriented Linear Dichroism to Probe Protein Orientation in Membrane Environments / A. Rodger ; J. Rajendra ; R. Mortimer ; T. Andrews ; J.D. Hirst ; A.T.B. Gilbert ; R. Marrington ; T.R. Dafforn ; D.J. Halsall ; M. Ardhammar ; B. Norden ; C.A. Woolhead ; C. Robinson ; T.J.T. Pinheiro ; J. Kazlauskaite ; M. Seymour ; N. Perez ; M.J. Hannon
Quantitative Protein Circular Dichroism Calculations / N.A. Besley
9.

図書

図書
David Whitford
出版情報: Chichester : Wiley, c2005  xiv, 528 p. ; 27 cm
所蔵情報: loading…
目次情報: 続きを見る
Preface
An introduction to protein structure and function / 1:
An Introduction to protein structure and function
Amino acids: the building blocks of proteins / 2:
A brief and very selective historical perspective
The three-dimensional structure of proteins / 3:
The biological diversity of proteins
The structure and function of fibrous proteins / 4:
Proteins and the sequencing of the human and other genomes
The structure and function of membrane proteins / 5:
Why study proteins?
The diversity of proteins / 6:
Enzyme kinetics, structure, function and catalysis / 7:
The 20 amino acids found in proteins / 8:
Protein synthesis, processing and turnover
The acid-base properties of amino acids / 9:
Protein expression, purification and characterization
Stereochemical representations of amino acids / 10:
Physical methods of determining the three-dimensional structure of proteins
Peptide bonds / 11:
Protein folding in vivo and in vitro
The chemical and physical properties of amino acids / 12:
Protein structure and a molecular approach to medicine
Epilogue
Detection, identification and quantification of amino acids and proteins
Glossary
Appendices
Stereoisomerism
Bibliography
References
Non-standard amino acids
Index
Summary
Problems
Primary structure or sequence
Secondary structure
Tertiary structure
Quaternary structure
The globin family and the role of quaternary structure in modulating activity
Immunoglobulins
Cyclic proteins
The amino acid composition and organization of fibrous proteins
Keratins
Fibroin
Collagen
The molecular organization of membranes
Membrane protein topology and function seen through organization of the erythrocyte membrane
Bacteriorhodopsin and the discovery of seven transmembrane helices
The structure of the bacterial reaction centre
Oxygenic photosynthesis
Photosystem I
Membrane proteins based on transmembrane [beta] barrels
Respiratory complexes
Complex III, the ubiquinol-cytochrome c oxidoreductase
Complex IV or cytochrome oxidase
The structure of ATP synthetase
ATPase family
Prebiotic synthesis and the origins of proteins
Evolutionary divergence of organisms and its relationship to protein structure and function
Protein sequence analysis
Protein databases
Gene fusion and duplication
Secondary structure prediction
Genomics and proteomics
Enzyme kinetics, structure, function, and catalysis
Enzyme nomenclature
Enzyme co-factors
Chemical kinetics
The transition state and the action of enzymes
The kinetics of enzyme action
Catalytic mechanisms
Enzyme structure
Lysozyme
The serine protease
Triose phosphate isomerase
Tyrosyl tRNA synthetase
EcoRI restriction endonuclease
Enzyme inhibition and regulation
Irreversible inhibition of enzyme activity
Allosteric regulation
Covalent modification
Isoenzymes or isozymes
Cell cycle
The structure of Cdk and its role in the cell cycle
Cdk-cyclin complex regulation
DNA replication
Transcription
Eukaryotic transcription factors: variation on a 'basic' theme
The spliceosome and its role in transcription
Translation
Transfer RNA (tRNA)
The composition of prokaryotic and eukaryotic ribosomes
A structural basis for protein synthesis
An outline of protein synthesis
Antibiotics provide insight into protein synthesis
Affinity labelling and RNA 'footprinting'
Structural studies of the ribosome
Post-translational modification of proteins
Protein sorting or targeting
The nuclear pore assembly
Protein turnover
Apoptosis
The isolation and characterization of proteins
Recombinant DNA technology and protein expression
Purification of proteins
Centrifugation
Solubility and 'salting out' and 'salting in'
Chromatography
Dialysis and ultrafiltration
Polyacrylamide gel electrophoresis
Mass spectrometry
How to purify a protein?
Introduction
The use of electromagnetic radiation
X-ray crystallography
Nuclear magnetic resonance spectroscopy
Cryoelectron microscopy
Neutron diffraction
Optical spectroscopic techniques
Vibrational spectroscopy
Raman spectroscopy
ESR and ENDOR
Factors determining the protein fold
Factors governing protein stability
Folding problem and Levinthal's paradox
Models of protein folding
Amide exchange and measurement of protein folding
Kinetic barriers to refolding
In vivo protein folding
Membrane protein folding
Protein misfolding and the disease state
Sickle cell anaemia
Viruses and their impact on health as seen through structure and function
HIV and AIDS
The influenza virus
p53 and its role in cancer
Emphysema and [alpha subscript 1]-antitrypsin
Preface
An introduction to protein structure and function / 1:
An Introduction to protein structure and function
文献の複写および貸借の依頼を行う
 文献複写・貸借依頼