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1.

図書

図書
Ronald L. Fournier
出版情報: Boca Raton : CRC Press, Taylor & Francis Group, c2018  xxix, 626 p. ; 27 cm
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図書

図書
edited by Antonio Trincone
出版情報: Boca Raton : CRC Press, c2019  xxiii, 527 p. ; 26 cm
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3.

図書

図書
editor, Donglu Shi
出版情報: New Jersey : World Scientific, c2015  xx, 236 p. ; 26 cm
シリーズ名: Frontiers in nanobiomedical research ; 4
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4.

図書

図書
edited by Marc Lamy de la Chapelle, Annemarie Pucci
出版情報: Singapore : Pan Stanford, c2013  xviii, 417 p., 16 p. of plates ; 24 cm
シリーズ名: Pan Stanford series on the high-tech of biotechnology ; v. 1
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目次情報: 続きを見る
Raman Spectroscopy Applied to Biomolecules Characterisation / C. Man
Biomedical Vibration Spectroscopy / W. Pietrich
Bioreceptor Functionalization of Gold-Coated Sensor Surfaces / R. Marks ; D. Prilutsky
Magnetic Nanoparticle Surface Functionalization for Biomedical applications / F. Geinguenaud, et al.
Plasmons in Low-Dimension Structures / T. Nagao
Antenna Interaction in the Infrared / D. Weber
Enhanced Spectroscopies and Surface Plasmon Thin Film Sensors / I. Abdulalhim
Nanostructures for Plasmonics: Design, Fabrication and Characterization / A. Toma, et al.
Surface Enhanced Infrared Spectroscopy / F. Neubrech ; A. Pucci
Surface Enhanced Raman Scattering: Application to Molecular Sensing / N. Felidj ; M. Lamy de la Chapelle
The SPR Biosensors / D. Barchiesi
Coherent Anti-Stokes Raman Scattering(CARS Microscopy) / N. Djaker
Multi-Signal Processing Biosensors and Bioactuators Based on Biocomputing Concept / E. Katz
Raman Spectroscopy Applied to Biomolecules Characterisation / C. Man
Biomedical Vibration Spectroscopy / W. Pietrich
Bioreceptor Functionalization of Gold-Coated Sensor Surfaces / R. Marks ; D. Prilutsky
5.

図書

図書
edited by Zhongwei Gu
出版情報: Weinheim : Wiley-VCH, c2015  xxi, 337 p. ; 25 cm
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List of Contributors
Preface
Backbone Degradable and Coiled-Coil Based Macromolecular Therapeutics / Jiyuan Yang ; Jindrich Kopecek1:
Introduction / 1.1:
Water-Soluble Polymers as Carriers of Anticancer Drugs / 1.2:
First Generation Conjugates - Design, Synthesis, and Activity / 1.2.1:
Analysis of Design Factors That Need Attention / 1.2.2:
Design of Conjugates for the Treatment of Noncancerous Diseases / 1.2.2.1:
Combination Therapy Using Polymer-Bound Therapeutics / 1.2.2.2:
New Targeting Strategies / 1.2.2.3:
Relationship Between Detailed Structure of the Conjugates and Their Properties / 1.2.2.4:
Impact of Binding a Drug to a Polymer on the Mechanism of Action / 1.2.2.5:
Mechanism of Internalization and Subcellular Trafficking / 1.2.2.6:
Relationship Between the Molecular Weight of the Carrier and the Efficacy of the Conjugate / 1.2.2.7:
Design of Second Generation Conjugates - Long-Circulating and Backbone Degradable / 1.2.3:
RAFT Copolymerization for the Synthesis of Conjugates / 1.2.3.1:
Click Reactions for Chain Extension into Multiblock Copolymers / 1.2.3.2:
Biological Properties of Long-Circulating Macromolecular Therapeutics / 1.2.3.3:
Summary of Part 2 and Future Prospects / 1.2.4:
Drug-Free Macromolecular Therapeutics - A New Paradigm in Drug Delivery / 1.3:
Biorecognition in Hybrid Polymer Systems / 1.3.1:
Coiled-Coils in Biomedical Systems / 1.3.2:
Coiled-Coil Based Drug-Free Macromolecular Therapeutics: Design, In Vitro, and In Vivo Activity / 1.3.3:
Potential, Limitations, and Future Prospect of Drug-Free Macromolecular Therapeutics / 1.3.4:
General Summary and Outlook / 1.4:
Acknowledgments
References
Dendritic Polymers as Targeting Nanoscale Drug Delivery Systems for Cancer Therapy / Kui Luo ; Zhongwei Gu2:
Functional Dendritic Polymers Based Drug Delivery Vehicles for Targeting Tumor Therapy via EPR Effect / 2.1:
Functional Dendritic Polymers for Encapsulation of Anticancer Drugs / 2.2.1:
Chemical Conjugation Functional Dendritic Polymers as Drug Delivery Systems / 2.2.2:
Tumor Targeting Moieties Functionalized Dendritic Drug Delivery Vehicles for Cancer Therapy / 2.3:
Conclusion / 2.4:
Composite Colloidal Nanosystems for Targeted Delivery and Sensing / Pilar Rivera Gil ; Moritz Nazarenus ; Wolfgang J. Parak3:
Working Toolkit / 3.1:
Engineering a Multifunctional Carrier / 3.1.2:
Objective / 3.2:
Cellular Behavior of the Carrier / 3.3:
Intracellular Fate / 3.3.1:
Biocompatibility / 3.3.2:
Applications / 3.4:
Delivery with Multifunctional PEM Capsules / 3.4.1:
Magnetic Targeting and Magnetofection / 3.4.1.1:
Strategies for Controlled Opening / 3.4.1.2:
Intracellular Ion Sensing / 3.4.2:
Conclusions / 3.5:
Abbreviations
Polymeric Micelles for Cancer-Targeted Drug Delivery / Huabing Chen ; Zhishen Ge ; Kazunori Kataoka4:
Micelle Formulations in Clinical Development / 4.1:
Particle Size of Micelles / 4.3:
Morphology of Micelles / 4.4:
Targeting Design of Micelles for Enhanced Accumulation and Cell Internalization / 4.5:
Functional Designs of Micelles / 4.6:
Design of Micelles for Gene Delivery / 4.7:
Challenge and Future Perspective 103 / 4.8:
Biomimetic Polymers for in Vivo Drug Delivery / Wenping Wang ; Kinam Park5:
Commonly Used Biomimetic Polymers and Their Applications in DDS / 5.1:
Polylactones and Their Modifications / 5.2.1:
Poly(lactic acid) (PLA) / 5.2.1.1:
Poly(lactic-co-glycolic acid) (PLGA) / 5.2.1.2:
Poly(ε-caprolactone) (PCL) / 5.2.1.3:
Dendrimer / 5.2.2:
Structure and Properties of Dendrimers / 5.2.2.1:
Types of Dendrimers / 5.2.2.2:
Applications of Dendrimers as Carriers in Drug Delivery Systems / 5.2.2.3:
Synthetic Polypeptides / 5.2.3:
Challenges and Perspectives / 5.3:
Drug Delivery from Protein-Based Nanoparticles / Dan Ding ; Xiqun Jiang6:
Preparation of Protein-Based Nanoparticles / 6.1:
Desolvation / 6.2.1:
Emulsification / 6.2.2:
Coacervation / 6.2.3:
Polymer-Monomer Pair Reaction System / 6.2.4:
Drug Delivery from Albumin-Based Nanoparticles / 6.3:
Albumin-Based Nanoparticles as Drug Carriers / 6.3.1:
Targeting Ligand-Functionalized Albumin-Based Nanoparticles / 6.3.2:
Nanoparticle Albumin-Bound (nab) Technology / 6.3.3:
Drug Delivery from Gelatin-Based Nanoparticles / 6.4:
Gelatin-Based Nanoparticles as Drug Carriers / 6.4.1:
Targeting Ligand-Functionalized Gelatin-Based Nanoparticles / 6.4.2:
Site-Specific Drug Delivery System / 6.4.3:
Drug Delivery from Other Protein-Based Nanoparticles / 6.5:
Polymeic Gene Carriers / Xuesi Chen ; Huayu Tian ; Xiuwen Guan7:
Gene Therapy and Gene Carriers / 7.1:
Gene Therapy / 7.1.1:
The Concept of Gene Therapy / 7.1.1.1:
Development and the Present Situation of Gene Therapy / 7.1.1.2:
Methods and Strategies of Gene Therapy / 7.1.1.3:
Research Contents and Challenges of Gene Therapy / 7.1.1.4:
Gene Carriers / 7.1.2:
The Concept of Gene Carrier / 7.1.2.1:
The Necessity of the Gene Carrier / 7.1.2.2:
Requirements of Gene Carrier / 7.1.2.3:
Classification of Gene Carrier / 7.1.2.4:
Polymeric Gene Carriers / 7.2:
Cationic Polymer Gene Carriers / 7.2.1:
Process of the Polycation Vector Mediated Gene Delivery / 7.2.1.1:
Categories and Research Situation of the Cationic Polymer Gene Vector / 7.2.1.2:
PEI Grafting Modification Polymeric Gene Carriers / 7.3:
Amino Acid Derivatives Modified Polymeric Gene Carriers / 7.3.1:
Poly(glutamic acid) Derivatives Modified PEI / 7.3.1.1:
Polyphenyialanine Derivatives Modified PEI / 7.3.1.2:
PEG Modified Hyperbranched PEI / 7.3.2:
Low Molecular Weight (LWM) PEI Base Polymeric Gene Carriers / 7.4:
Crosslinked Polycations / 7.4.1:
Crosslinlced Polycation OEI-CBA / 7.4.1.1:
Crosslinked Polycation OEI-PBLG-PEGDA / 7.4.1.2:
Hexachlorotriphosphazene Crosslinked Polycation / 7.4.1.3:
Grafted Polycations / 7.4.2:
Grafted Cationic Polymer MP-g-OEI / 7.4.2.1:
Graft Cationic Polymer N-PAE-g-OEI / 7.4.2.2:
Graft Cationic Polymer mPEGT-PMCC-g-OEI / 7.4.2.3:
Targeted Shielding System for Polymeric Gene Carriers / 7.5:
Static Shielding System / 7.5.1:
Poly(glutamine acid) Shielding System and PEGylations / 7.5.1.1:
Sulfonamides Related Shielding System / 7.5.1.2:
Other Design Strategies of Cationic Gene Carrier / 7.5.2:
pH-Sensitive Polymeric Nanoparticles as Carriers for Cancer Therapy and Imaging / Yi Li ; Guang Hui Gao ; Ick Chan Kwon ; Doo Sung Lee7.6:
pH-Sensitive Polymers / 8.1:
pH-Sensitive Anionic Polymers / 8.2.1:
pH-Sensitive Cationic Polymers / 8.2.2:
pH-Sensitive Neutral Polymers / 8.2.3:
pH-Sensitive Polymers as Drug Carriers / 8.3:
pH-Sensitive Polymer-Drug Conjugates / 8.3.1:
pH-Sensitive Polymeric Micelles / 8.3.2:
pH-Sensitive Polymersomes / 8.3.3:
pH-Sensitive Polymer-Inorganic Hybrid Nanoparticles / 8.3.4:
pH-Sensitive Dendrimers / 8.3.5:
pH-Sensitive Polymers for Bioimaging / 8.4:
Charge-Reversal Polymers for Biodelivery / Bo Zhan ; Kai Wang ; Jingxing Si ; Meihua Sui ; Youqing Shen8.5:
Applications of Cationic Polymers in Biodelivery / 9.1:
Barriers for Cationic Polymers in In vitro and In vivo Applications / 9.2:
Characteristic pH Gradients in Tumor Interstitium and Endo/Lyso somes / 9.3:
Chemistry of Charge-Reversal Polymers Based on Acid-Labile Amides / 9.4:
pHe-Triggered Charge-Reversal / 9.4.1:
pHL-Triggered Charge-Reversal / 9.4.2:
Applications of Charge-Reversal Polymers in Biodelivery Systems / 9.5:
Charge-Reversal in Cancer Drug Delivery / 9.5.1:
Charge-Reversal in Gene Delivery / 9.5.2:
Charge-Reversal in Protein Delivery / 9.5.3:
Charge-Reversal Incorporated with Inorganic Materials / 9.5.4:
Perspectives / 9.6:
Phenylbaronic Acid-Containing Glucose-Responsive Polymer Materials: Synthesis and Applications in Drug Delivery / Rujiang Ma ; Linqi Shi10:
PBA-Containing Polymers Operating Under Physiological Conditions / 10.1:
Chemically Crosslinked PBA-Based Gels / 10.3:
Self-Assembled PBA-Based Polymer Micelles / 10.4:
Self-Assembled PBA-Based Polymersomes / 10.5:
Extracellular pH-Activated Nanocarriers for Enhanced Drug Delivery to Tumors / You-Yong Yuan ; Cheng-Qiong Mao ; Jin-Zhi Du ; Xian-Zhu Yang ; Jun Wang10.6:
Passive and Active Tumor Targeting / 11.1:
Targeting the Extracellular pH (pHe) in Tumors / 11.3:
Extracellular pH-Induced Drug Delivery to Tumors / 11.4:
Ligand Exposure by a Shielding/Deshielding Method / 11.5:
Surface Charge Reversing Nanoparticles / 11.6:
Enhanced Cellular Uptake by Surface Charge Reversing Nanoparticles / 11.6.1:
Overcoming MDR by Surface Charge Reversing Nanoparticles / 11.6.2:
Enhanced Delivery of siRNA by Surface-Charge Reversing Nanoparticles / 11.6.3:
Stimulation-Sensitive Drug Delivery Systems / Xintao Shuai ; Du Cheng11.7:
pH-Sensitive Delivery Systems / 12.1:
pH-Sensitive Micellar Delivery Systems / 12.2.1:
pH-Sensitive Liposomes / 12.2.2:
Thermo-Sensitive Delivery Systems / 12.3:
Biomolecule-Sensitive Delivery Systems / 12.4:
Enzyme-Sensitive Nanocarriers / 12.4.1:
Reduction-Responsive Conjugates / 12.4.2:
Other Environmentally Sensitive Nanocarriers / 12.5:
Outlook / 12.6:
Index
List of Contributors
Preface
Backbone Degradable and Coiled-Coil Based Macromolecular Therapeutics / Jiyuan Yang ; Jindrich Kopecek1:
6.

図書

図書
Steven Ripp, Theodore B. Henry, editor[s] ; sponsored by the ACS Division of Agrochemicals
出版情報: Washington, DC : American Chemical Society , [New York] : Distributed in print by Oxford University Press, c2011  x, 190 p. ; 24 cm
シリーズ名: ACS symposium series ; 1079
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7.

図書

図書
edited by Valery A. Petrenko, George P. Smith
出版情報: Cambridge, UK : RSC Publishing, c2011  xiv, 273 p. ; 24 cm
シリーズ名: RSC nanoscience & nanotechnology ; no. 17
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目次情報: 続きを見る
The Phage Nanoparticle Toolkit / George P. SmithChapter 1:
Introduction / 1.1:
Virion Structure and Purification / 1.2:
Intrusion / 1.3:
DNA Replication Cycle and Gene Expression / 1.4:
Extrusion of Progeny Virions / 1.5:
Display of Guest Peptides / 1.6:
The Engineer's Toolkit / 1.7:
Acknowledgements
References
The Roles of Structure, Dynamics and Assembly in the Display of Peptides on Filamentous Bacteriophage / Stanley J. OpellaChapter 2:
Molecular and Structural Biology of Filamentous Bacteriophage / 2.1:
Packaging of the Genome into Filamentous Bacteriophage / 2.2:
Structural Form of the Major Coat Protein / 2.3:
Membrane-bound Form of Filamentous Bacteriophage Coat Proteins / 2.4:
Assembly / 2.5:
Phage Display / 2.6:
Conclusion / 2.7:
Quantitative Analysis of Peptide Libraries / Lee MakowskiChapter 3:
Assessing the Quality of a Phage-displayed Library / 3.1:
Peptide Sequence Censorship / 3.2.1:
Experimental Measures / 3.2.2:
Conceptual Measures / 3.2.3:
Quantitative Measures / 3.2.4:
Assessing the Quality of an Affinity Screen Experiment / 3.3:
Change in Diversity / 3.3.1:
Change in Information / 3.3.2:
Identification of Motifs in a Peptide Population / 3.4:
Similarity Matrices / 3.5:
Identification of Binding Sites in Proteins / 3.6:
Identification of Binding Proteins in a Proteome / 3.7:
Relic / 3.8:
Discussion
Phage-mediated Drug Delivery / Valery A. Petrenko ; Prashanth K. JayannaChapter 4:
Targeting of Drugs/Drug Carrier Systems / 4.1:
Targeting Ligands / 4.3:
Phage-displayed Libraries as a Source of Peptide Targeting Ligands / 4.4:
Bacteriophage Capsid-mediated Drug Delivery / 4.5:
Drug-bearing Filamentous Phage as Targeted Chemotherapeutics / 4.6:
Phage Fusion Proteins as Targeting Ligands for Nanomedicines / 4.7:
Imaging with Bacteriophage-derived Probes / Susan L. Deutscher ; Kimberly A. Kelly4.8:
Selection of Bacteriophage as Imaging Probes / 5.1:
Imaging Agents / 5.1.1:
Phage Nanoparticles / 5.1.2:
Phage Display for Imaging Probe Discovery / 5.1.3:
Radiolabled Phage as Imaging Agents / 5.2:
Optical Molecular Imaging with Phage / 5.3:
Phage-based Pathogen Biosensors / Suiqiong Li ; Ramji S. Lakshmanan ; Bryan A. Chin5.4:
Threat of Pathogenic Microorganisms / 6.1:
Pathogen Detection Techniques / 6.1.2:
Current Trends and Existing Methodologies for Pathogen Detection / 6.2:
Conventional Pathogen Detection Techniques / 6.2.1:
Polymerase Chain Reaction (PCR) / 6.2.2:
Enzyme-linked Immunosorbent Assay (ELISA) / 6.2.3:
Biosensor Techniques / 6.2.4:
Biomolecular Recognition Element / 6.2.5:
Whole Filamentous Bacteriophage Particles as a Biorecognition Probe / 6.3:
Phage Immobilization on Biosensor Platforms / 6.3.1:
Current Trends in Development of Phage-based Biosensors / 6.3.2:
Phage-based Magnetoelastic Particle Resonator Biosensors / 6.4:
Magnetoelastic (ME) Particle Resonator Sensor Platform / 6.4.1:
Fabrication of the Sensor Platform / 6.4.2:
ME Biosensor Assembly / 6.4.3:
Performance of Phage-based ME Biosensors / 6.4.4:
Phage-mediated Detection of Biological Threats / Steven Ripp6.5:
Phage Typing Schemes / 7.1:
Exploiting Phage Specificity for Bacterial Detection / 7.3:
Labeled Phage / 7.3.1:
Reprter Phage / 7.3.2:
Phage Amplification / 7.3.3:
Electrochemical-based Sensing Assays / 7.3.4:
Surface Plasmon Resonance-based Sensing Assays / 7.3.5:
The Phage-mediated Adenylate Kinase Assay / 7.3.6:
Genetically Engineered Virulent Phage Banks for the Detection and Control of Bacterial Biosecurity Threats / Francois Iris ; Flqvie Pouillot ; Helene Blois ; Manuel Geo ; Paul-Henri Lampe7.4:
Host Range engineering / 8.1:
Production of a Genetically Engineered T4 Phage Bank with Vastly Increased Host Range / 8.3:
Reversible Inhibition of the T4 Lytic Cycle Within the Bacterial Host / 8.4:
Large-scale Recombinations into the Genomes of an Infective Wild-type T4 Population / 8.5:
Construction of a T4 Bank of Host Range Variants / 8.6:
Conclusion and Perspectives / 8.7:
Methods / 8.9:
High-fidelity PCR / 8.9.1:
Error-prone PCR / 8.9.2:
Selective High-fidelity Amplification of Desired Fragments / 8.9.3:
Reconstruction of Sequence Through PCR / 8.9.4:
DNA Sequencing and Analysis / 8.9.5:
Production and Expression of Non-functional E. coli Rho Genes / 8.9.6:
Construction and Expression of the Heat-inducible Red-Recombinase System / 8.9.7:
Site-directed Chemical Modification of Phage Particles / Lana Saleh ; Christopher J. NorenChapter 9:
Unique Chemical Properties of Selenocysteine Compared with Cysteine / 9.1:
In vivo Incorporation of Sec by E. coli / 9.3:
Construction of Selenopeptide-displayed Phage Libraries / 9.4:
Applications Using Selenopeptide Phage Display / 9.5:
Screening for Sec Insertion in vivo: Investigating the Stringency of E. coli SECIS Requirements Using Phage Display / 9.5.1:
Catalysis-based Selection of Novel Enzyme Activities from Substrate-appended Phage Libraries / 9.5.2:
Mechanical Manipulation of M13 Phage / 9.5.3:
Filamentous Fhage-templated Synthesis and Assembly of Inorganic Nanomaterials / Binrui Cao ; Chuanbin Mao9.6:
Virion Structure and Phage Display / 10.1:
Biology / 10.2.1:
Chemistry / 10.2.2:
Site-specific Engineering of the Virion Surface / 10.2.3:
Liquid Crystalline Behavior / 10.2.4:
Exploiting Phage Display to Alter Surface Chemistry by Selection Rather Than Rational Design225 / 10.3:
Random Peptide Libraries225 / 10.3.1:
Affinity Selection ('Biopanning')226 / 10.3.2:
Synthesis and Assembly of Inorganic Materials on Individual Virions / 10.4:
Synthesis and Assembly of Inorganic Materials on a Self-assembled Phage Scaffold / 10.5:
Applications of Phage-templated Nanomaterials / 10.6:
Summary and Outlook / 10.7:
Phage Vaccines and Phage Therapy / Karen ManoutcharianChapter 11:
Introduction to Phage / 11.1:
Phage Immunogens / 11.2:
Epitope Discovery with Phage Libraries and Phage Vaccines / 11.3:
Autoimmune Disorders / 11.4:
Cancer / 11.5:
Neurological Disorders / 11.6:
Other Diseases / 11.7:
Antibacterial Therapy / 11.8:
Subject Index
The Phage Nanoparticle Toolkit / George P. SmithChapter 1:
Introduction / 1.1:
Virion Structure and Purification / 1.2:
8.

図書

図書
Xuefei Huang, Joseph J. Barchi, Jr., editor[s] ; sponsored by the ACS Division of Carbohydrate Chemistry
出版情報: Washington, DC : American Chemical Society , [New York] : Distributed in print by Oxford University Press, c2011  xi, 227p. ; 24 cm
シリーズ名: ACS symposium series ; 1091
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図書

図書
Bernd H.A. Rehm
出版情報: Norfolk : Caister Academic Press, c2013  viii, 309, 17 p ; 24 cm
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10.

図書

図書
edited by Challa S. S. R. Kumar
出版情報: Weinheim : Wiley-VCH, c2010  xxii, 564 p. ; 25 cm
シリーズ名: Nanomaterials for the life sciences / edited by Challa S.S.R. Kumar ; v. 7
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