Introduction and Background / Part I: |
Life / Chapter 1: |
Prokaryotes / 1.: |
Partial table of contents: Life |
Aqueous Solutions / 2.: |
Biomolecules |
Eukaryotes |
Amino Acids |
Techniques of Protein Purification / 3.: |
Covalent Structures of Proteins |
Biochemistry: A Prologue |
Hemoglobin: Protein Function in Microcosm |
Lipids and Membranes / 4.: |
Mechanisms Of Enzyme Action |
Genetics: A Review |
Rates of Enzymatic Reactions |
Enzymatic Catalysis / 5.: |
Metabolism |
The Origin of Life |
Glycolysis |
Glycogen Metabolism / 6.: |
Transport Through Membranes |
The Biochemical Literature |
Citric Acid Cycle |
Electron Transport and Oxidative Phosphorylation / Chapter 2: |
Photosynthesis |
Lipid Metabolism |
Nucleotide Metabolism |
The Expression And Transmission Of Genetic Information |
Properties of Water |
DNA: The Vehicle of Inheritance |
Nucleic Acid Structures and Manipulation |
Translation |
Acids, Bases, and Buffers |
DNA Replication, Repair, and Recombination |
Eukaryotic Gene Expression / Chapter 3: |
Molecular Physiology |
Thermodynamic Principles: A Review |
Index |
First Law of Thermodynamics: Energy Is Conserved |
Second Law of Thermodynamics: The Universe Tends toward Maximum Disorder |
Free Energy: The Indicator of Spontaneity |
Chemical Equilibria |
Concentration Dependence of Free Energy / Appendix: |
The Amino Acids of Proteins / Part II: |
Optical Activity |
"Nonstandard" Amino Acids |
Nucleic Acids, Gene Expression, and Recombinant DNA Technology / Chapter 5: |
Nucleotides and Nucleic Acids |
DNA Is the Carrier of Genetic Information |
Double Helical DNA |
Gene Expression and Replication: An Overview |
Molecular Cloning |
Techniques of Protein and Nucleic Acid Purification / Chapter 6: |
Protein Isolation |
Solubilities of Proteins |
Chromatographic Separations |
Electrophoresis |
Ultracentrifugation |
Nucleic Acid Fractionation |
Covalent Structures of Proteins and Nucleic Acids / Chapter 7: |
Primary Structure Determination of Proteins |
Nucleic Acid Sequencing |
Chemical Evolution |
Bioinformatics: An Introduction |
Chemical Synthesis of Polypeptides |
Chemical Synthesis of Oligonucleotides |
Three-Dimensional Structures of Proteins / Chapter 8: |
Secondary Structure |
Fibrous Proteins |
Globular Proteins |
Protein Stability |
Quaternary Structure |
Viewing Stereo Pictures |
Protein Folding, Dynamics, and Structural Evolution / Chapter 9: |
Protein Folding: Theory and Experiment |
Folding Accessory Proteins |
Protein Structure Prediction and Design |
Protein Dynamics |
Conformational Diseases: Amyloids and Prions |
Structural Evolution |
Hemoglobin Function / Chapter 10: |
Structure and Mechanism |
Abnormal Hemoglobins |
Allosteric Regulation |
Derivation of Symmetry Model Equations |
Sugars and Polysaccharides / Chapter 11: |
Monosaccharides |
Polysaccharides |
Glycoproteins |
Lipid Classification / Chapter 12: |
Properties of Lipid Aggregates |
Biological Membranes |
Membrane Assembly and protein Targeting |
Lipoproteins |
Mechanisms of Enzyme Action / Part III: |
Introduction to Enzymes / Chapter 13: |
Historical Perspective |
Substrate Specificity |
Coenzymes |
Regulation of Enzymatic Activity |
A Primer of Enzyme Nomenclature |
Chemical Kinetics / Chapter 14: |
Enzyme Kinetics |
Inhibition |
Effects of pH |
Bisubstrate Reactions |
Derivations of Michaelis-Menten Equation Variants |
Catalytic Mechanisms / Chapter 15: |
Lysozyme |
Serine Proteases |
Drug Design |
Introduction to Metabolism / Part IV: |
Metabolic Pathways |
Organic Reaction Mechanisms |
Experimental Approaches to the Study of Metabolism |
Thermodynamics of Phosphate Compounds |
Oxidation-Reduction Reactions |
Thermodynamics of Life |
The Glycolytic Pathway / Chapter 17: |
The Reactions of Glycolysis |
Fermentation: The Anaerobic Fate of Pyruvate |
Metabolic Regulation and Control |
Metabolism of Hexoses Other than Glucose |
Glycogen Breakdown / Chapter 18: |
Glycogen Synthesis |
Control of Glycogen Metabolism |
Glycogen Storage Diseases |
Signal Transduction / Chapter 19: |
Hormones |
Heterotrimeric G Proteins |
Tyrosine Kinase-Based Signaling |
The Phosphoinositide Cascade |
Transport through Membranes / Chapter 20: |
Thermodynamics of Transport |
Kinetics and Mechanisms of Transport |
ATP-Driven Active Transport |
Ion Gradient-Driven Active Transport |
Neurotransmission |
Cycle Overview / Chapter 21: |
Metabolic Sources of Acetyl-Coenzyme A |
Enzymes of the Citric Acid Cycle |
Regulation of the Citric Acid Cycle |
The Amphibolic Nature of the Citric Acid Cycle |
The Mitochondrion / Chapter 22: |
Electron Transport |
Oxidative Phosphorylation |
Control of ATP Production |
Other Pathways of Carbohydrate Metabolism / Chapter 23: |
Gluconeogenesis |
The Glyoxylate Cycle |
Biosynthesis of Oligosaccharides and Glycoproteins |
The Pentose Phosphate Pathway |
Chloroplasts / Chapter 24: |
Light Reactions |
Dark Reactions |
Lipid Digestion, Absorption, and Transport / Chapter 25: |
Fatty Acid Oxidation |
Ketone Bodies |
Fatty Acid Biosynthesis |
Regulation of Fatty Acid Metabolism |
Cholesterol Metabolism |
Eicosanoid Metabolism: Prostaglandins, Prostacyclins, Thromboxanes, Leukotrienes, and Lipoxins / 7.: |
Phospholipid and Glycolipid Metabolism / 8.: |
Amino Acid Metabolism / Chapter 26: |
Amino Acid Deamination |
The Urea Cycle |
Metabolic Breakdown of Individual Amino Acids |
Amino Acids as Biosynthetic Precursors |
Amino Acid Biosynthesis |
Nitrogen Fixation |
Energy Metabolism: Integration and Organ Specialization / Chapter 27: |
Major Pathways and Strategies of Energy Metabolism: A Summary |
Organ Specialization |
Metabolic Homeostasis: Regulation of Appetite, Energy Expenditure, and Body Weight |
Metabolic Adaptation |
Synthesis of Purine Ribonucleotides / Chapter 28: |
Synthesis of Pyrimidine Ribonucleotides |
Formation of Deoxyribonucleotides |
Nucleotide Degradation |
Biosynthesis of Nucleotide Coenzymes |
Expression and Transmission of Genetic Information / Part V: |
Nucleic Acid Structures / Chapter 29: |
Double Helical Structures |
Forces Stabilizing Nucleic Acid Structures |
Supercoiled DNA |
DNA Replication: An Overview / Chapter 30: |
Enzymes of Replication |
Prokaryotic Replication |
Eukaryotic Replication |
Repair of DNA |
Recombination and Mobile Genetic Elements |
DNA Methylation and Trinucleotide Repeat Expansions |
Transcription / Chapter 31: |
The Role of RNA in Protein Synthesis |
RNA Polymerase |
Control of Transcription in Prokaryotes |
Posttranscriptional Processing |
The Genetic Code / Chapter 32: |
Transfer RNA and Its Aminoacylation |
Ribosomes and Polypeptide Synthesis |
Control of Eukaryotic Translation |
Posttranslational Modification |
Protein Degradation |
Viruses: Paradigms for Cellular Function / Chapter 33: |
Tobacco Mosaic Virus |
Icosahedral Viruses |
Bacteriophage [lambda] |
Influenza Virus |
Chromosome Structure / Chapter 34: |
Genomic Organization |
Control of Expression |
Cell Differentiation and Growth |
Blood Clotting / Chapter 35: |
Immunity |
Motility: Muscles, Cilia, and Flagella |
Introduction and Background / Part I: |
Life / Chapter 1: |
Prokaryotes / 1.: |