| Hemocyanins / K.E. van Holde and K.I. Miller |
| Molten Globule and Protein Folding / O.B. Ptitsyn |
| Enthalpic Contribution to Protein Stability: Insights from Atom-Based Calculations and Statistical Mechanics / T. Lazaridis ; G. Archontis ; M. Karplus |
| Energetics of Protein Structure / G.I. Makhatadze ; P.L. Privalov |
| Chapter References |
| Author Index |
| Subject Index |
| Preface |
| Structural Basis of Effector Regulation and Signal Termination in Heterotrimeric G[alpha] Proteins / Stephen R. Sprang ; Zhe Chen ; Xinlin Du |
| Introduction and Scope / I： |
| A Selective Survey of G[alpha]Protein Structurc and Function / II： |
| Mechanisms of Effector Recognition and Regulation by G[alpha]GTP / III： |
| Signal Termination: The Mechanism of GTP Hydrolysis and Conformational Deactivation / IV： |
| Signal Termination Through GAPs and Effector GAP Domains / V： |
| Conclusions / VI： |
| References |
| Receptors Activate G Proteins? / William M. Oldham ; Heidi E. HammHow Do： |
| Introduction |
| Toward a Model of the Receptor-G Protein Complex |
| Molecular Basis for G Protein Activation |
| Summary and Conclusions |
| Some Mechanistic Insights into GPCR Activation from Detergent-Solubilized Ternary Complexes on Beads / Tione Buranda ; Anna Waller ; Yang Wu ; Peter C. Simons ; Sean Biggs ; Eric R. Prossnitz ; Larry A. Sklar |
| Perspectives |
| Survey of Experimental Approaches and Representative Data |
| Analysis of Soluble Receptor Ternary Complex Assemblies |
| Guanine Nucleotide Activation of Ternary Complex: Some Dynamic Aspects of Structure and Reactivity |
| Activation of G Protein-Coupled Receptors / Xavier Deupi ; Brian Koblika |
| Structural and Mechanistic Homology Among GPCRs |
| Conformational States |
| Activation by Agonists |
| Concluding Remarks |
| Kinetic Analysis of G Protein-Coupled Receptor Signaling Using Fluorescence Resonance Energy Transfer in Living Cells / Martin J. Lohse ; Carsten Hoffmann ; Viacheslav O. Nikolaev ; Jean-Pierre Vilardaga ; Moritz Bunemann |
| Assays and Methods |
| Results and Discussion |
| Regulation of Rho Guanine Nucleotide Exchange Factors by G Proteins / Paul C. Sternweis ; Angela M. Carter ; Shahab M. Danesh ; Ying-Fan Hsiung ; William D. Singer |
| RGS-RhoGEFs |
| Mechanisms of Regulation |
| Physiological Function of the RGS-RhoGEFs |
| Structure and Catalytic Mechanism of Secretory Phospholipases / D.L. Scott ; P.B. Sigler |
| Lipid-Binding Proteins: A Family of Fatty Acid and Retinoid Transport Proteins / L. Banaszak ; N. Winter ; Z. Xu ; D.A. Bernlohr ; S. Cowan ; T.A. Jones |
| Structure of Serum Albumin / D.C. Carter ; J.X. Ho |
| Apolipoprotein B. and Low-Density Lipoprotein Structure: Implications for Biosynthesis of Triglyceride-Rich Lipoproteins / V.N. Schumaker ; M.L. Phillips ; J.E. Chatterton |
| Apolipoprotein E: Structure-Function Relationships / K.H. Weisgraber |
| The Amphipathic-Helix: A Multifunctional Structural Motif in Plasma Apolipoproteins / J.P. Segrest ; D.W. Garber ; C.B. Brouillette ; S.C. Harvey ; G.M. Ananntharamaiah |
| Lipophorin: The Structure of an Insect Lipoprotein and Its Role in Lipid Transport in Insects / J.L. Soulages ; M.A. Wells |
| Hsien Wu and the First Theory of Protein Denaturation (1931) / J.T. Edsall |
| Studies on Denaturation of Proteins XIII: A Theory of Denaturation / H. Wu |
| Free Energy Balance in Protein Folding / B. Honig ; A.-S. Yang |
| Modeling Protein Stability as Heteropolymer Collapse / K.A. Dill ; D. Stigter |
| Protein Destabilization at Low Temperatures / F. Franks |
| Stability of (-Helices / A. Chakrabartty ; R.L. Baldwin |
| Engineering the Stability and Function of Gene V Protein / T.C. Terwilliger |
| Staphylococcal Nuclease: A Showcase of m-Value Effects / D. Shortle |
| Studies on Protein Stability with T4 Lysozyme / B.W. Matthews |
| Structure and Stability of Membrane Proteins / M.H.B. Stowell and D.C. Rees |
| Hemocyanins / K.E. van Holde and K.I. Miller |
| Molten Globule and Protein Folding / O.B. Ptitsyn |
| Enthalpic Contribution to Protein Stability: Insights from Atom-Based Calculations and Statistical Mechanics / T. Lazaridis ; G. Archontis ; M. Karplus |
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