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1.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2001  xxi, 634 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 66
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2.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2000  xxv, 613 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 65
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目次情報: 続きを見る
Symposium Participants
Foreword
Mutation Response and Error Bypass
Understanding the Complexity of an Organism's Responses to DNA Damage / G.C. Walker
DNA Repair Systems and Bacterial Evolution / M. Radman ; F. Taddei ; I. Matic
Adaptive Mutation in Escherichia coli / P.L. Foster
The Biochemical Basis and In Vivo Regulation of SOS-induced Mutagenesis Promoted by Escherichia coli DNA Polymerase V (UmuD'[subscript 2]C) / M.F. Goodman ; R. Woodgate
Human DNA Polymerase [kappa] A Novel DNA Polymerase of Unknown Biological Function Encoded by the DINBI Gene / V.L. Gerlach ; W.J. Feaver ; P.L. Fischhaber ; J.A. Richardson ; L. Aravind ; E.V. Koonin ; K. Bebenek ; T.A. Kunkel ; E.C. Friedberg
Role of Yeast and Human DNA Polymerase [eta] in Error-free Replication of Damaged DNA / S. Prakash ; R.E. Johnson ; M.T. Washington ; L. Haracska ; C.M. Kondratick ; L. Prakash
Roles of DNA Polymerase [xi] and Rev1 Protein in Eukaryotic Mutagenesis and Translesion Replication / C.W. Lawrence ; P.E.M. Gibbs ; R.S. Murante ; X.-D. Wang ; Z. Li ; T.P. McManus ; W.G. McGregor ; J.R. Nelson ; D.C. Hinkle ; V.M. Maher
Xeroderma Pigmentosum Variant: From a Human Genetic Disorder to a Novel DNA Polymerase / C. Masutani ; R. Kusumoto ; A. Yamada ; M. Yuasa ; M. Araki ; T. Nogimori ; M. Yokoi ; T. Eki ; S. Iwai ; F. Hanaoka
Streisinger Revisited: DNA Synthesis Errors Mediated by Substrate Misalignments
Base Recognition and Excision Repair
Roles of Watson-Crick and Minor Groove Hydrogen Bonds in DNA Replication / E.T. Kool
Structural and Mechanistic Studies on Repair of 8-Oxoguanine in Mammalian Cells / S.D. Bruner ; D.P.G. Norman ; J.C. Fromme ; G.L. Verdine
Envisioning the Fourth Dimension of the Genetic Code: The Structural Biology of Macromolecular Recognition and Conformational Switching in DNA Repair / K.-P. Hopfner ; S.S. Parikh ; J.A. Tainer
Repair of Endogenous DNA Damage / T. Lindahl ; D.E. Barnes
Base Removers and Strand Scissors: Different Strategies Employed in Base Excision and Strand Incision at Modified Base Residues in DNA / E. Seeberg ; L. Luna ; I. Morland ; L. Eide ; B. Johnsen ; E. Larsen ; I. Alseth ; F. Dantzer ; K. Baynton ; R. Aamodt ; K.I. Kristiansen ; T. Rognes ; A. Klungland ; M. Bjoras
DNA Polymerase [beta] and Mammalian Base Excision Repair / S.H. Wilson ; R.W. Sobol ; W.A. Beard ; J.K. Horton ; R. Prasad ; B.J. Vande Berg
Photolyase/Cryptochrome Family Blue-light Photoreceptors Use Light Energy to Repair DNA or Set the Circadian Clock / A. Sancar ; C. Thompson ; R.J. Thresher ; F. Araujo ; J. Mo ; S. Ozgur ; E. Vagas ; L. Dawut ; C.P. Selby
Nucleotide Excision Repair
DNA Damage Recognition and Nucleotide Excision Repair in Mammalian Cells / R.D. Wood ; S.J. Araujo ; R.R. Ariza ; D.P. Batty ; M. Biggerstaff ; E. Evans ; P.-H. Gaillard ; D. Gunz ; B. Koberle ; I. Kuraoka ; J.G. Moggs ; J.K. Sandall ; M.K.K. Shivji
Regulation of Nucleotide Excision Repair in Bacteria and Mammalian Cells / P.C. Hanawalt ; D.J. Crowley ; J.M. Ford ; A.K. Ganesan ; D.R. Lloyd ; T. Nouspikel ; C.A. Smith ; G. Spivak ; S. Tornaletti
Three-dimensional Structure and Function of Replication Protein A / G. Mer ; A. Bochkarev ; W.J. Chazin ; A.M. Edwards
Transcription-coupled Repair of Oxidative DNA Damage in Human Cells: Mechanisms and Consequences / S. Tsutakawa ; P.K. Cooper
Mismatch Repair
Signaling Mismatch Repair: The Mechanics of an Adenosine-Nucleotide Molecular Switch / R. Fishel ; S. Acharya ; M. Berardini ; T. Bocker ; N. Charbonneau ; A. Cranston ; S. Gradia ; S. Guerrette ; C.D. Heinen ; A. Mazurek ; T. Snowden ; C. Schmutte ; K.-S. Shim ; G. Tombline ; T. Wilson
DNA Mismatch Repair: From Structure to Mechanism / W. Yang ; M.S. Junop ; C. Ban ; G. Obmolova ; P. Hsieh
New Recognition Mode for a TG Mismatch: The Atomic Structure of a Very Short Patch Repair Endonuclease-DNA Complex / S.E. Tsutakawa ; K. Morikawa
Temporary and Permanent Mutators Lacking the Mismatch Repair System: The Enhancement of Mutators in Cell Populations / J.H. Miller ; A. Yeung ; P. Funchain ; E. Mao ; J. Stewart ; W.M. Clendenin ; M.M. Slupska
Telomeres and the Stability of DNA Ends
Molecular Manifestations and Molecular Determinants of Telomere Capping / E.H. Blackburn ; S. Chan ; J. Chang ; T.B. Fulton ; A. Krauskopf ; M. McEachern ; J. Prescott ; J. Roy ; C. Smith ; H. Wang
A New Connection at Human Telomeres: Association of the Mre11 Complex with TRF2 / T. de Lange ; J.H.J. Petrini
Telomere Length, Telomere-binding Proteins, and DNA Damage Signaling / M.T. Hemann ; J. Hackett ; A. IJpma ; C.W. Greider
All Things Must End: Telomere Dynamics in Yeast / M.L. DuBois ; S.J. Diede ; A.E. Stellwagen ; D.E. Gottschling
Sir2: An NAD-dependent Histone Deacetylase That Connects Chromatin Silencing, Metabolism, and Aging / S. Imai ; F.B. Johnson ; R.A. Marciniak ; M. McVey ; P.U. Park ; L. Guarente
Arrest, Adaptation, and Recovery following a Chromosome Double-strand Break in Saccharomyces cerevisiae / S.E. Lee ; A. Pellicioli ; J. Demeter ; M.P. Vaze ; A.P. Gasch ; A. Malkova ; P.O. Brown ; D. Botstein ; T. Stearns ; M. Foiani ; J.E. Haber
Double-strand Break Repair in Human Cells / S.C. West ; C. Chappell ; L.A. Hanakahi ; J.-Y. Masson ; M.J. McIlwraith ; E. Van Dyck
Damage Control during Replication and Mitosis
Controlling S-phase Onset in Fission Yeast / Z. Lygerou ; P. Nurse
Coping with and Recovering from Hydroxyurea-induced Replication Fork Arrest in Budding Yeast / J.F.X. Diffley ; K. Bousset ; K. Labib ; E.A. Noton ; C. Santocanale ; J.A. Tercero
Damage Response and dNTP Regulation: The Interaction between Ribonucleotide Reductase and Its Inhibitor, Sml1 / B. Georgieva ; X. Zhao ; R. Rothstein
Is Rad9p Upstream or Downstream from mec1p? / E.J. Foss
DNA Damage Checkpoint Control of Mitosis in Fission Yeast / N. Rhind ; B.A. Baber-Furnari ; A. Lopez-Girona ; M.N. Boddy ; J.-M. Brondello ; B. Moser ; P. Shanahan ; A. Blasina ; C. McGowan ; P. Russell
Mitotic Checkpoints, Genetic Instability, and Cancer / M. Dobles ; P.K. Sorger
Microscopy-induced Radiation Damage, Microtubules, and Progression through the Terminal Stage of G[subscript 2] (Prophase) in Vertebrate Somatic Cells / C.L. Rieder ; R. Cole
Genome Stability and Checkpoint Control
Complexity of Damage Produced by Ionizing Radiation / J.F. Ward
Complex Transcriptional Responses to Macromolecular Damaging Agents: Regulatory Responses Specific for S[subscript N]2 Alkylation and the MAG1 Gene / T.J. Begley ; S.A. Jelinsky ; L.D. Samson
The Interplay between Nonhomologous End-joining and Cell Cycle Checkpoint Factors in Development, Genomic Stability, and Tumorigenesis / D.O. Ferguson ; J.M. Sekiguchi ; K.M. Frank ; Y. Gao ; N.E. Sharpless ; Y. Gu ; J. Manis ; R.A. DePinho ; F.W. Alt
S-phase Functions of the Mre11 Complex
The FHA Domain, a Phosphoamino Acid Binding Domain Involved in the DNA Damage Response Pathway / M. Huang ; S.J. Elledge
The FHA Domain in DNA Repair and Checkpoint Signaling / D. Durocher ; S.J. Smerdon ; M.B. Yaffe ; S.P. Jackson
Details and Concerns Regarding the G[subscript 2]/M DNA Damage Checkpoint in Budding Yeast / T. Weinert ; E. Little ; L. Shanks ; A. Admire ; R. Gardner ; C. Putnam ; R. Michelson ; K. Nyberg ; P. Sundareshan
Establishment of and Recovery from Damage Checkpoint Requires Sequential Interactions of Crb2 with Protein Kinases Rad3, Chk1, and Cdc2 / F. Esashi ; S. Mochida ; T. Matsusaka ; T. Obara ; A. Ogawa ; K. Tamai ; M. Yanagida
Analysis of the Fission Yeast Checkpoint Rad Proteins / T. Caspari ; C. Davies ; A.M. Carr
A Conserved Role for the Hus1 Checkpoint Protein in Eukaryotic Genome Maintenance / R.S. Weiss ; P. Leder ; T. Enoch
DNA-damage-induced Checkpoint Pathways in the Nematode Caenorhabditis elegans / E.R. Hofmann ; S. Milstein ; M.O. Hengartner
@p53 and the DNA Damage Response
The Transcriptional Program following p53 Activation / R. Zhao ; K. Gish ; M. Murphy ; Y. Yin ; D. Notterman ; W.H. Hoffman ; E. Tom ; D.H. Mack ; A.J. Levine
Regulation of p53 after Different Forms of Stress and at Different Cell Cycle Stages / V. Gottifredi ; S.Y. Shieh ; C. Prives
The DNA Damage Checkpoint and Human Cancer / L.B. Schultz ; N.H. Chehab ; A. Malikzay ; R.A. DiTullio, Jr. ; E.S. Stavridi ; T.D. Halazonetis
DNA Damage Responses and Chemosensitivity in the E[mu]-myc Mouse Lymphoma Model / C.A. Schmitt ; R.R. Wallace-Brodeur ; C.T. Rosenthal ; M.E. McCurrach ; S.W. Lowe
Genetic Instability, Oncogenes, and the p53 Pathway / G. Wahl ; O. Vafa
DNA Damage and Cancer Progression
Multiple Signaling Pathways Involving ATM / M.B. Kastan ; D.-S. Lim ; S.-T. Kim ; B. Xu ; C. Canman
ATM: Sounding the Double-strand Break Alarm / Y. Shiloh
Interactions of the Nijmegen Breakage Syndrome Protein with ATM and BRCA1 / X. Wu ; G. Rathbun ; W.S. Lane ; D.T. Weaver ; D.M. Livingston
The Function of BRCA1 in DNA Damage Response / J.-S. Lee ; K. Collins ; A. Brown ; C.-H. Lee ; J.H. Chung
Recombination between Two Chromosomes: Implications for Genomic Integrity in Mammalian Cells / C. Richardson ; M. Jasin
Transcription-coupled Repair: A Multifunctional Signaling Pathway / S.A. Leadon
Chromosomal Instability and Cancer Predisposition: Insights from Studies on the Breast Cancer Susceptibility Gene, BRCA2 / A.R. Venkitaraman
Roles of RecQ Family Helicases in the Maintenance of Genome Stability / L. Wu ; S.L. Davies ; I.D. Hickson
Role of DNA Break-sensing Molecule Poly(ADP-ribose) Polymerase (PARP) in Cellular Function and Radiation Toxicity / W.-M. Tong ; D. Galendo ; Z.-Q. Wang
Summary: Biological Responses to DNA Damage: A Perspective in the New Millennium
Author Index
Subject Index
Symposium Participants
Foreword
Mutation Response and Error Bypass
3.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: New York : Cold Spring Harbor Laboratory Press, 2004  xxvii, 532 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 69
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4.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Woodbury, N.Y. : Cold Spring Harbor Laboratory Press, 2009  xxiii, 485 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 74
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5.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Plainview, N.Y. : Cold Spring Harbor Laboratory Press, 1998  xxxx, 679 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 63
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6.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: New York : Cold Spring Harbor Laboratory Press, 2003  xxv, 512 p ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; 68
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7.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Plainview, N.Y. : Cold Spring Harbor Laboratory Press, 1999  xxvi, 621 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 64
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目次情報: 続きを見る
Symposium Participants
Foreword
Lymphocyte Development
Lymphoid Development from Stem Cells and the Common Lymphocyte Progenitors / K. Akashi ; M. Kondo ; S. Cheshier ; J. Shizuru ; K. Gandy ; J. Domen ; R. Mebius ; D. Traver ; I.L. Weissman
PU.1, a Shared Transcriptional Regulator of Lymphoid and Myeloid Cell Fates / H. Singh ; R.P. DeKoter ; J.C. Walsh
Differentiation, Dedifferentiation, and Redifferentiation of B-lineage Lymphocytes: Roles of the Surrogate Light Chain and the Pax5 Gene / A. Rolink ; S. Nutt ; M. Busslinger ; E. ten Boekel ; T. Seidl ; J. Andersson ; F. Melchers
Notch and the CD4 Versus CD8 Lineage Decision / P. Valdez ; E. Robey
Consequences of Notch-mediated Inhibition of the Transcription Factor E47 / W. Pear ; Z. Tang ; S. DeRocco ; D. Allman ; R. Hardy ; J. Pui ; L. Xu ; F. Karnell ; J. Aster ; T. Kadesch
Role of Helix-Loop-Helix Proteins in Lymphocyte Development / C. Murre
Controlling Lymphopoiesis with a Combinatorial E-protein Code / R.J. Barndt ; Y. Zhuang
The Molecular Basis of B-cell Lineage Commitment / S.L. Nutt ; A.G. Rolink
Role of B-lymphocyte-induced Maturation Protein-1 in Terminal Differentiation of B Cells and Other Cell Lineages / C. Angelin-Duclos ; G. Cattoretti ; D.H. Chang ; K.-I. Lin ; Y. Lin ; J. Yu ; K. Calame
The Lymphochip: A Specialized cDNA Microarray for the Genomic-scale Analysis of Gene Expression in Normal and Malignant Lymphocytes / A. Alizadeh ; M. Eisen ; R.E. Davis ; C. Ma ; H. Sabet ; T. Tran ; J.I. Powell ; L. Yang ; G.E. Marti ; D.T. Moore ; J.R. Hudson, Jr. ; W.C. Chan ; T. Greiner ; D. Weisenburger ; J.O. Armitage ; I. Lossos ; R. Levy ; D. Botstein ; P.O. Brown ; L.M. Staudt
Transcription Factors and the Control of Lymphocyte Development
Ikaros Chromatin Remodeling Complexes in the Control of the Differentiation of the Hemo-lymphoid System / J. Koipally ; J. Kim ; B. Jones ; A. Jackson ; N. Avitahl ; S. Winandy ; M. Trevisan ; A. Nichogiannopoulou ; C. Kelley ; K. Georgopoulos
Mechanisms of Transcriptional Regulation in Lymphocyte Progenitors: Insight from an Analysis of the Terminal Transferase Promoter / P. Ernst ; K. Hahm ; B.S. Cobb ; K.E. Brown ; L.A. Trinh ; A.S. McCarty ; M. Merkenschlager ; C.A. Klug ; A.G. Fisher ; S.T. Smale
Mechanisms of [mu] Enhancer Regulation in B Lymphocytes / B.S. Nikolajczyk ; W. Dang ; R. Sen
Differential Regulation of Immunoglobulin Gene Transcription via Nuclear Matrix-associated Regions / C. Webb ; R.-T. Zong ; D. Lin ; Z. Wang ; M. Kaplan ; Y. Paulin ; E. Smith ; L. Probst ; J. Bryant ; A. Goldstein ; R. Scheuermann ; P. Tucker
B-cell-specific Coactivator OCA-B: Biochemical Aspects, Role in B-Cell Development and Beyond / Y. Luo ; R.G. Roeder
Control of Lymphocyte Differentiation by the LEF-1/TCF Family of Transcription Factors / T. Reya ; R. Okamura ; R. Grosschedl
Activation and Repression of Wingless/Wnt Target Genes by the TCF/LEF-1 Family of Transcription Factors / H.C. Korswagen ; H.C. Clevers
The INF-[beta] Enhancer: A Paradigm for Understanding Activation and Repression of Inducible Gene Expression / N. Munshi ; J. Yie ; M. Merika ; K. Senger ; S. Lomvardas ; T. Agalioti ; D. Thanos
Recombination and Allelic Exclusion
V(D)J Recombination: Links to Transposition and Double-strand Break Repair / M. Gellert ; J.E. Hesse ; K. Hiom ; M. Melek ; M. Modesti ; T.T. Paull ; D.A. Ramsden ; D.C. van Gent
Nonhomologous End-joining Proteins Are Required for V(D)J Recombination, Normal Growth, and Neurogenesis / J.M. Sekiguchi ; Y. Gao ; Y. Gu ; K. Frank ; Y. Sun ; J. Chaudhuri ; C. Zhu ; H.-L. Cheng ; J. Manis ; D. Ferguson ; L. Davidson ; M.E. Greenberg ; F.W. Alt
Regulation of Chromatin Accessibility for V(D)J Recombination / C. Hernandez-Munain ; M. Taylor McMurry ; M.S. Krangel
What Prevents Intermolecular V(D)J Recombination? / L.E. Huye ; J.-O. Han ; D.B. Roth
Demethylation and the Establishment of [kappa] Allelic Exclusion / R. Mostoslavsky ; A. Kirillov ; Y.-H. Ji ; M. Goldmit ; M. Holzmann ; T. Wirth ; H. Cedar ; Y. Bergman
RAG Expression in B Cells in Secondary Lymphoid Tissues / W. Yu ; H. Nagaoka ; Z. Misulovin ; E. Meffre ; H. Suh ; M. Jankovic ; N. Yannoutsos ; R. Casellas ; E. Besmer ; F. Papavasiliou ; X. Qin ; M.C. Nussenzweig
Antibody Diversification and Selection in the Mature B-Cell Compartment / M.S. Neuberger ; A. Lanoue ; M.R. Ehrenstein ; F.D. Batista ; J.E. Sale ; G.T. Williams
Molecular Mechanism of Immunoglobulin Class Switch Recombination / K. Kinoshita ; C.-G. Lee ; J. Tashiro ; M. Muramatsu ; X.-C. Chen ; K. Yoshikawa ; T. Honjo
Molecular Aspects of Somatic Hypermutation of Immunoglobulin Genes / U. Storb ; A. Peters ; N. Kim ; H.M. Shen ; G. Bozek ; N. Michael ; J. Hackett, Jr. ; E. Klotz ; J.D. Reynolds ; L.A. Loeb ; T.E. Martin
T-cell Activation and Receptor Signaling
Structural, Biochemical, and Biophysical Studies of HLA-A2/Altered Peptide Ligands Binding to Viral-peptide-specific Human T-cell Receptors / B.M. Baker ; Y.-H. Ding ; D.N. Garboczi ; W.E. Biddison ; D.C. Wiley
Visualizing T-cell Recognition / M.M. Davis ; C. Wulfing ; M.F. Krummel ; P.A. Savage ; J. Xu ; C. Sumen ; M.L. Dustin ; Y.-H. Chien
Three Signals and a Master Switch in the Regulation of T-cell Immunity / A. Lanzavechia
Studies on the Adapter Molecule LAT / L.E. Samelson ; S.C. Bunnell ; R.P. Trible ; T. Yamazaki ; W. Zhang
The Adapter Proteins LAT and SLP-76 Are Required for T-cell Activation / T.S. Finco ; D. Yablonski ; J. Lin ; A. Weiss
Signaling in Primary Thymocytes after Presentation of Altered Peptide Ligands by Antigenpresenting Cells or MHC-peptide Tetramers / L.A. Smyth ; L. Reynolds ; R. Tyrrell ; O. Williams ; T. Norton ; T. Schumacher ; V. Tybulewicz ; S.C. Ley ; D. Kioussis
The Impact of Pre-T-cell Receptor Signals on Gene Expression in Developing T Cells / H. von Boehmer ; I. Aifantis ; O. Azogui ; C. Saint-Ruf ; F. Grassi
The PTK-STAT Signaling Pathway Has Essential Roles in T-cell Activation in Response to Antigen Stimulation / T. Welte ; D. Leitenberg ; B.N. Dittel ; B. K. al-Ramadi ; W.R. Hansen ; B. Xie ; C.A. Janeway, Jr. ; A.L.M. Bothwell ; K. Bottomly ; X.-Y. Fu
CTLA-4--The Costimulatory Molecule That Doesn't: Regulation of T-cell Responses by Inhibition / C.A. Chambers ; J.P. Allison
B-cell Activation and Receptor Signaling
Mechanisms of Self-tolerance and Autoimmunity: From Whole-animal Phenotypes to Molecular Pathways / C.C. Goodnow ; R. Glynne ; D. Mack ; B. Weintraub ; J. Rathmell ; J.I. Healy ; S. Chaudhry ; L. Miosge ; A. Loy ; L. Wilson
The Maintenance and the Activation Signal of the B-cell Antigen Receptor / M. Reth ; J. Wienands
Inhibitory Receptors and Their Modes of Action / D.C. Fong ; J.C. Cambier
Cell Death and Survival in the Immune System
Genetic Analysis of Apoptotic and Survival Signals / T.W. Mak ; W.-C. Yeh
Death and Survival Signals Determine Active/Inactive Conformations of Pro-apoptotic BAX, BAD, and BID Molecules / S.J. Korsmeyer ; A. Gross ; H. Harada ; J. Zha ; K. Wang ; X.-M. Yin ; M. Wei ; S. Zinkel
Control of Apoptosis in Hematopoietic Cells by the Bcl-2 Family of Proteins / J.M. Adams ; D.C.S. Huang ; H. Puthalakath ; P. Bouillet ; G. Vairo ; K. Moriishi ; G. Hausmann ; L. O'Reilly ; K. Newton ; S. Ogilvy ; M.L. Bath ; C.G. Print ; A.W. Harris ; A. Strasser ; S. Cory
RIPs: An Emerging Family of Kinases Involved in Pro-inflammatory and Apoptotic Signaling / V.M. Dixit
Receptor-mediated Apoptosis in T Lymphocytes / J. Zhang ; A. DeYoung ; H.G. Kasler ; N.H. Kabra ; A.A. Kuang ; G. Diehl ; S.J. Sohn ; C. Bishop ; A. Winoto
Role of the Nuclear Hormone Receptor ROR[gama] in Transcriptional Regulation, Thymocyte Survival, and Lymphoid Organogenesis / D.R. Littman ; Z. Sun ; D. Unutmaz ; M.J. Sunshine ; H.T. Petrie ; Y.-R. Zou
What Keeps a Resting T Cell Alive? / C.B. Thompson ; J.C. Rathmell ; K.A. Frauwirth ; T. Lindsten ; C.M. Rudin ; J.T. Opferman ; P.G. Ashton-Rickardt ; M.H. Harris ; N.S. Chandel ; P.T. Schumacker ; M.G. Vander Heiden
Cytokine Signaling and Responses
Differential Roles of Cytokine Signaling during T-cell Development / R. Moriggl ; J.-C. Marine ; D.J. Topham ; S. Teglund ; V. Sexl ; C. McKay ; R. Piekorz ; D. Wang ; E. Parganas ; A. Yoshimura ; J.N. Ihle
Negative Regulation of Cytokine Signaling by the SOCS Proteins / N.A. Nicola ; S.E. Nicholson ; D. Metcalf ; J.-G. Zhang ; M. Baca ; A. Farley ; T.A. Willson ; R. Starr ; W. Alexander ; D.J. Hilton
IL-4 Signaling Is Regulated through the Recruitment of Phosphatases, Kinases, and SOCS Proteins to the Receptor Complex / J. Losman ; X.P. Chen ; H. Jiang ; P.-Y. Pan ; M. Kashiwada ; C. Giallourakis ; S. Cowan ; K. Foltenyi ; P. Rothman
Signaling via the IL-2 and IL-7 Receptors from the Membrane to the Nucleus / W.J. Leonard ; K. Imada ; H. Nakajima ; A. Puel ; E. Soldaini ; S. John
Potential Roles of Stat1 and Stat3 in Cellular Transformation / J.F. Bromberg ; J.E. Darnell, Jr.
Innate Immune Induction of the Adaptive Immune Response / R. Medzhitov
Attenuation of Tumor Necrosis Factor [alpha] Gene Transcription in Macrophages by an Autocrine Factor / M. Baer ; S. Nedospasov ; P.F. Johnson
Mechanism of Chromatin Recognition and Transcriptional Regulation by LEF-1 and the Wnt/Wg-responsive LEF-1:[beta]-Catenin Complex / A. Tutter ; G.S. McAlpine ; K.A. Jones
HIV and SIV Nef Modulate Signal Transduction and Protein Sorting in T Cells / J. Skowronski ; M. Lock ; R. Mariani ; S. Salghetti ; T. Swigut ; A.J. Iafrate
Transcrption Factor IRF-1 and Its Family Members in the Regulation of Host Defense / T. Taniguchi ; N. Tanaka ; K. Ogasawara ; S. Taki ; M. Sato ; A. Takaoka
NF-[kappa]B/NF-AT/TRAF
NF-[kappa]B Activation by Tumor Necrosis Factor and Interleukin-1 / Z. Cao ; M. Tanaka ; C. Regnier ; M. Rothe ; A. Yamit-hezi ; J.D. Woronicz ; M.E. Fuentes ; M.H. Durnin ; S.A. Dalrymple ; D.V. Goeddel
Role of NF-[kappa]B in T-lymphocyte Development / R.E. Voll ; S. Ghosh
The I[kappa]B Kinase: A Master Regulator of NF-[kappa]B, Innate Immunity, and Epidermal Differentiation / M. Delhase ; M. Karin
Signaling through Calcium, Calcineurin, and NF-AT in Lymphocyte Activation and Development / K. Stankunas ; I.A. Graef ; J.R. Neilson ; S.-H. Park ; G.R. Crabtree
NF-AT5: The NF-AT Family of Transcription Factors Expands in a New Direction / C. Lopez-Rodriguez ; J. Aramburu ; A.S. Rakeman ; N.G. Copeland ; D.J. Gilbert ; S. Thomas ; C. Disteche ; N.A. Jenkins ; A. Rao
Signal Integration by Transcription-factor Assemblies: Interactions of NFAT1 and AP-1 on the IL-2 Promoter / L. Chen ; S.C. Harrison
Structure and Mechanism in NF-[kappa]B/I[kappa]B Signaling / T. Huxford ; S. Malek ; G. Ghosh
Structural Studies of Human TRAF2 / H. Wu ; Y.C. Park ; H. Ye ; L. Tong
Structural and Biochemical Analysis of Signal Transduction by the TRAF Family of Adapter Proteins / S.M. McWhirter ; S.S. Pullen ; B.G. Werneburg ; M.E. Labadia ; R.H. Ingraham ; J.J. Crute ; M.R. Kehry ; T. Alber
T-cell Differentiation
Molecular Basis of T-cell Differentiation / R.A. Flavell ; B. Li ; C. Dong ; H.-T. Lu ; D.D. Yang ; H. Enslen ; C. Tournier ; A. Whitmarsh ; M. Wysk ; D. Conze ; M. Rincon ; R.J. Davis
Tissue-specific Regulation of Cytokine Gene Expression / I.-C. Ho ; J.I. Kim ; S.J. Szabo ; L.H. Glimcher
Bi-stable Transcriptional Circuitry and GATA-3 Auto-activation in Th2 Commitment / K.M. Murphy ; W. Ouyang ; S. Ranganath ; T.L. Murphy
Multiple Levels of Regulation of Th2 Cytokine Gene Expression / N. Arai ; H.J. Lee ; I. Ferber ; H. Kurata ; A. O'Garra
Bias in the Expression of IL-4 Alleles: The Use of T Cells from a GFP Knock-in Mouse / C. Pannetier ; J. Hu-Li ; W.E. Paul
Summary: Signals and Beyond
Author Index
Subject Index
Symposium Participants
Foreword
Lymphocyte Development
8.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology
出版情報: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, 2002  xxi, 566 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 67
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Symposium Participants
Foreword
Development of the Cardiovascular System
Cardiogenesis in the Drosophila Model: Control Mechanisms during Early Induction and Diversification of Cardiac Progenitors / S. Zaffran ; X. Xu ; P.C.H. Lo ; H.-H. Lee ; M. Frasch
Regulation of Cardiac Muscle Differentiation in Xenopus laevis Embryos / T. Mohun ; B. Latinkic ; N. Towers ; S. Kotecha
Genetic Regulation of Cardiac Patterning in Zebrafish / D. Yelon ; J.L. Feldman ; B.R. Keegan
Zebrafish Hearts and Minds: Nodal Signaling in Cardiac and Neural Left-Right Asymmetry / S. Long ; N. Ahmad ; M. Rebagliati
Cardiac Left-Right Development: Are the Early Steps Conserved? / K.L. Kramer ; H.J. Yost
Erythropoietin and Retinoic Acid Signaling in the Epicardium Is Required for Cardiac Myocyte Proliferation / I. Stuckmann ; A.B. Lassar
Endocardial Cushion Formation in Zebrafish / D.Y.R. Stainier ; D. Beis ; B. Jungblut ; T. Bartman
Neural Crest Migration and Mouse Models of Congenital Heart Disease / A.D. Gitler ; C.B. Brown ; L. Kochilas ; J. Li ; J.A. Epstein
Transcription Factors in Cardiovascular Development
Hey bHLH Factors in Cardiovascular Development / A. Fischer ; C. Leimeister ; C. Winkler ; N. Schumacher ; B. Klamt ; H. Elmasri ; C. Steidl ; M. Maier ; K.-P. Knobeloch ; K. Amann ; A. Helisch ; M. Sendtner ; M. Gessler
Molecular Mechanisms of Chamber-specific Myocardial Gene Expression: Transgenic Analysis of the ANF Promoter / E.M. Small ; P.A. Krieg
Pitx Genes during Cardiovascular Development / C. Kioussi ; P. Briata ; S.H. Baek ; A. Wynshaw-Boris ; D.W. Rose ; M.G. Rosenfeld
Pitx2 and Cardiac Development: A Molecular Link between Left/Right Signaling and Congenital Heart Disease / M. Campione ; L. Acosta ; S. Martinez ; J.M. Icardo ; A. Aranega ; D. Franco
Regulation of Cardiac Growth and Development by SRF and Its Cofactors / D. Wang ; R. Passier ; Z.-P. Liu ; C.H. Shin ; Z. Wang ; S. Li ; L.B. Sutherland ; E. Small ; E.N. Olson
Homeodomain Factor Nkx2-5 in Heart Development and Disease / R.P. Harvey ; D. Lai ; D. Elliott ; C. Biben ; M. Solloway ; O. Prall ; F. Stennard ; A. Schindeler ; N. Groves ; L. Lavulo ; C. Hyun ; T. Yeoh ; M. Costa ; M. Furtado ; E. Kirk
Causes of Clinical Diversity in Human TBX5 Mutations / T. Huang ; J.E. Lock ; A.C. Marshall ; C. Basson ; J.G. Seidman ; C.E. Seidman
Molecular Mechanisms of Ventricular Hypoplasia / D. Srivastava ; P.D. Gottlieb
Hypoxia, HIFs, and Cardiovascular Development / M.C. Simon ; D. Ramirez-Bergeron ; F. Mack ; C.-J. Hu ; Y. Pan ; K. Mansfield
Quiescent Hypervascularity Mediated by Gain of HIF-1[alpha] Function / J.M. Arbeit
Vascular Biology
The Diverse Roles of Integrins and Their Ligands in Angiogenesis / R.O. Hynes ; J.C. Lively ; J.H. McCarty ; D. Taverna ; S.E. Francis ; K. Hodivala-Dilke ; Q. Xiao
Arteries, Veins, Notch, and VEGF / B.M. Weinstein ; N.D. Lawson
Cell Cycle Signaling and Cardiovascular Disease / E.G. Nabel ; M. Boehm ; L.M. Akyurek ; T. Yoshimoto ; M.F. Crook ; M. Olive ; H. San ; X. Qu
Selective Functions of Angiopoietins and Vascular Endothelial Growth Factor on Blood Vessels: The Concept of "Vascular Domain" / T.N. Sato ; S. Loughna ; E.C. Davis ; R.P. Visconti ; C.D. Richardson
Survival Mechanisms of VEGF and PlGF during Microvascular Remodeling / J.N. Upalakalin ; I. Hemo ; C. Dehio ; E. Keshet ; L.E. Benjamin
Molecular Mechanisms of Lymphangiogenesis / T. Makinen ; K. Alitalo
Protease-activated Receptors in the Cardiovascular System / S.R. Coughlin
Migration of Monocytes/Macrophages In Vitro and In Vivo Is Accompanied by MMP12-dependent Tunnel Formation and by Neovascularization / M. Anghelina ; A. Schmeisser ; P. Krishnan ; L. Moldovan ; R.H. Strasser ; N.I. Moldovan
The Role of EG-VEGF in the Regulation of Angiogenesis in Endocrine Glands / J. LeCouter ; R. Lin ; N. Ferrara
Profiling the Molecular Diversity of Blood Vessels / R. Pasqualini ; W. Arap
Tumor Angiogenesis
VEGF-A Induces Angiogenesis, Arteriogenesis, Lymphangiogenesis, and Vascular Malformations / J.A. Nagy ; E. Vasile ; D. Feng ; C. Sundberg ; L.F. Brown ; E.J. Manseau ; A.M. Dvorak ; H.F. Dvorak
Angiogenesis and Lymphangiogenesis in Tumors: Insights from Intravital Microscopy / R.K. Jain
A Genetic Approach to Understanding Tumor Angiogenesis / R. Benezra ; P. de Candia ; H. Li ; E. Romero ; D. Lyden ; S. Rafii ; M. Ruzinova
Discovery of Type IV Collagen Non-collagenous Domains as Novel Integrin Ligands and Endogenous Inhibitors of Angiogenesis / R. Kalluri
Complementary and Coordinated Roles of the VEGFs and Angiopoietins during Normal and Pathologic Vascular Formation / N.W. Gale ; G. Thurston ; S. Davis ; S.J. Wiegand ; J. Holash ; J.S. Rudge ; G.D. Yancopoulos
Involvement of G Proteins in Vascular Permeability Factor/Vascular Endothelial Growth Factor Signaling / D. Mukhopadhyay ; H. Zeng
Targeted Delivery of Mutant Raf Kinase to Neovessels Causes Tumor Regression / J.D. Hood ; D.A. Cheresh
Combining Antiangiogenic Agents with Metronomic Chemotherapy Enhances Efficacy against Late-stage Pancreatic Islet Carcinomas in Mice / G. Bergers ; D. Hanahan
Genetics and Genomics of the Cardiovascular System
Zebrafish: The Complete Cardiovascular Compendium / C.A. MacRae ; M.C. Fishman
Consomic Rats for the Identification of Genes and Pathways Underlying Cardiovascular Disease / R.J. Roman ; A.W. Cowley, Jr. ; A. Greene ; A.E. Kwitek ; P.J. Tonellato ; H.J. Jacob
A Mouse Model of Congenital Heart Disease: Cardiac Arrhythmias and Atrial Septal Defect Caused by Haploinsufficiency of the Cardiac Transcription Factor Csx/Nkx2.5 / M. Tanaka ; C.I. Berul ; M. Ishii ; P.Y. Jay ; H. Wakimoto ; P. Douglas ; N. Yamasaki ; T. Kawamoto ; J. Gehrmann ; C.T. Maguire ; M. Schinke ; Y. Kurachi ; S. Izumo
Genetic Dissection of the DiGeorge Syndrome Phenotype / F. Vitelli ; E.A. Lindsay ; A. Baldini
A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine-induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel / M. Eldar ; E. Pras ; H. Lahat
Regulation of the Heart
Calcium-dependent Gene Regulation in Myocyte Hypertrophy and Remodeling / R.S. Williams ; P. Rosenberg
A Gradient of Myosin Regulatory Light-chain Phosphorylation across the Ventricular Wall Supports Cardiac Torsion / J.S. Davis ; S. Hassanzadeh ; S. Winitsky ; H. Wen ; A. Aletras ; N.D. Epstein
Molecular and Functional Maturation of the Murine Cardiac Conduction System / S. Rentschler ; G.E. Morley ; G.I. Fishman
The Yin/Yang of Innate Stress Responses in the Heart / D.L. Mann
Regulatory Networks Controlling Mitochondrial Energy Production in the Developing, Hypertrophied, and Diabetic Heart / B.N. Finck ; J.J. Lehman ; P.M. Barger ; D.P. Kelly
Heart Disease and Failure
Molecular Epidemiology of Hypertrophic Cardiomyopathy / H. Morita ; S.R. DePalma ; M. Arad ; B. McDonough ; S. Barr ; C. Duffy ; B.J. Maron
The Sarcoglycan Complex in Striated and Vascular Smooth Muscle / M.T. Wheeler ; M.J. Allikian ; A. Heydemann ; E.M. McNally
The MLP Family of Cytoskeletal Z Disc Proteins and Dilated Cardiomyopathy: A Stress Pathway Model for Heart Failure Progression / M. Hoshijima ; M. Pashmforoush ; R. Knoll ; K.R. Chien
From Sarcomeric Mutations to Heart Disease: Understanding Familial Hypertrophic Cardiomyopathy / A. Maass ; J.P. Konhilas ; B.L. Stauffer ; L.A. Leinwand
Vascular Endothelium in Tissue Remodeling: Implications for Heart Failure / S.M. Dallabrida ; M.A. Rupnick
Using a Gene-switch Transgenic Approach to Dissect Distinct Roles of MAP Kinases in Heart Failure / B.G. Petrich ; P. Liao ; Y. Wang
G-Protein-coupled Receptor Function in Heart Failure / S.V. Naga Prasad ; J. Nienaber ; H.A. Rockman
Hypertension, Atherosclerosis, and Lipid Homeostasis
Salt and Blood Pressure: New Insight from Human Genetic Studies / R.P. Lifton ; F.H. Wilson ; K.A. Choate ; D.S. Geller
Gene-targeting Studies of the Renin--Angiotensin System: Mechanisms of Hypertension and Cardiovascular Disease / S.B. Gurley ; T.H. Le ; T.M. Coffman
Modulation of Endothelial NO Production by High-density Lipoprotein / C. Mineo ; P.W. Shaul
Plaque Angiogenesis: Its Functions and Regulation / K.S. Moulton
Extracellular Superoxide Dismutase, Uric Acid, and Atherosclerosis / H.U. Hink ; T. Fukai
SREBPs: Transcriptional Mediators of Lipid Homeostasis / J.D. Horton ; J.L. Goldstein ; M.S. Brown
Genetic Defenses against Hypercholesterolemia / H.H. Hobbs ; G.A. Graf ; L. Yu ; K.R. Wilund ; J.C. Cohen
Repairing the Cardiovascular System
Insulin-like Growth Factor Isoforms in Skeletal Muscle Aging, Regeneration, and Disease / N. Winn ; A. Paul ; A. Musaro ; N. Rosenthal
Cellular Therapies for Myocardial Infarct Repair / C.E. Murry ; M.L. Whitney ; M.A. Laflamme ; H. Reinecke ; L.J. Field
Gene Therapy for Cardiac Arrhythmias / E. Marban ; H.B. Nuss ; J.K. Donahue
Myocardial Disease in Failing Hearts: Defective Excitation--Contraction Coupling / X.H.T. Wehrens ; A.R. Marks
Summary: The Coming of Age of Cardiovascular Science
Author Index
Subject Index
Symposium Participants
Foreword
Development of the Cardiovascular System
9.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology ; Cold Spring Harbor Laboratory
出版情報: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory, 1987  xix, 955 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 52
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10.

図書

図書
Cold Spring Harbor Symposium on Quantitative Biology ; Cold Spring Harbor Laboratory of Quantitative Biology
出版情報: Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory , Tokyo : University of Tokyo Press, 1973  xii, 706 p. ; 28 cm
シリーズ名: Cold Spring Harbor symposia on quantitative biology ; v. 37
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