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1.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c2002  lix, 810 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 39
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Preface to the Series
Preface to Volume 39
In Memoriam of Professor Robert C. Bray
Contributors
Contents of Previous Volumes
Handbook on Toxicity of Inorganic Compounds
Handbook on Metals in Clinical and Analytical Chemistry
Handbook on Metalloproteins
The Biogeochemistry of Molybdenum and Tungsten / Edward I. StiefelChapter 1:
Introduction / 1.:
Molybdenum and Tungsten in the Environment / 2.:
The Nitrogen Cycle / 3.:
Sulfur Metabolism and the Sulfur Cycle / 4.:
Carbon Metabolism / 5.:
Arsenic, Selenium, and Chlorine Metabolism / 6.:
Conclusion / 7.:
Acknowledgment
Abbreviations
References
Transport, Homeostasis, Regulation, and Binding of Molybdate and Tungstate to Proteins / Richard N. Pau ; David M. LawsonChapter 2:
Competition with Iron(III)
Transport Systems
Cytoplasmic Molybdate-Binding Proteins
Conclusions
Acknowledgments
Abbreviations and Definitions
Molybdenum Nitrogenases: A Crystallographic and Mechanistic View / Barry E. SmithChapter 3:
The Nitrogenases
The Molybdenum-Iron Protein
The Iron Protein
Mechanistic Studies
The Nitrogenase Complex
The Active Site
Chemical Dinitrogen Fixation by Molybdenum and Tungsten Complexes: Insights From Coordination Chemistry / Masanobu Hidai ; Yasushi Mizobe8.:
Preparation and Structures of Dinitrogen Complexes
Reactions of Coordinated Dinitrogen
Biosynthesis of the Nitrogenase Iron-Molybdenum-Cofactor From Azotobacter Vinelandii / Jeverson Frazzon ; Dennis R. DeanChapter 5:
Biochemical Genetic Analysis of FeMo Cofactor Biosynthesis
A General Model for FeMo Cofactor Biosynthesis
Mobilization of Iron and Sulfur
NifB Cofactor
The NifEN Complex
Homocitrate Formation and Molybdenum Insertion
Role of Intermediate Carriers in FeMo Cofactor Biosynthesis
Role of the Iron Protein in Cofactor Assembly / 9.:
Summary and Future Prospects / 10.:
Molybdenum Enzymes Containing the Pyranopterin Cofactor: an Overview / Russ HilleChapter 6:
Classification of the Mononuclear Molybdenum Enzymes
Consideration of Selected Enzymes Not Covered in Other Chapters
Mechanistic Considerations
Concluding Remarks
The Molybdenum and Tungsten Cofactors: A Crystallographic View / Holger Dobbek ; Robert HuberChapter 7:
Structure of the Mo/W Cofactor
Moco-Containing Enzyme Families
Limitations of a Crystallographic Model
Models for the Pyranopterin-Containing Molybdenum and Tungsten Cofactors / Berthold Fischer ; Sharon J. Nieter BurgmayerChapter 8:
Early Models
Model Complexes of 1,2-Ene-Dithiolates
Metal Complexes of Pterins
Models with All Three Redox Sites
Biosynthesis and Molecular Biology of the Molybdenum Cofactor (Moco) / Ralf R. Mendel ; Gunter SchwarzChapter 9:
Genetics of the Molybdenum Cofactor
Biosynthesis of the Molybdenum Cofactor
Regulation of Molybdenum Cofactor Synthesis
Molybdenum in Nitrate Reductase and Nitrite Oxidoreductase / Peter M. H. Kroneck ; Dietmar J. AbtChapter 10:
Bacterial Respiratory Chains, Metalloenzymes, and Bioenergetics
Nitrate Reductase
Nitrite Oxidoreductase
Environmental Aspects and Biosensors
The Molybdenum-Containing Hydroxylases of Nicotinate, Isonicotinate, and Nicotine / Jan R. Andreesen ; Susanne FetznerChapter 11:
Hydroxylations of Nicotinate and Derivatives
Catabolism of Isonicotinate and Derivatives
Nicotine Catabolism: Enzymes and Genes Involved in Aerobic Transformations
Biotechnological Potentials and Medical Implications
The Molybdenum-Containing Xanthine Oxidoreductases and Picolinate Dehydrogenases / Emil F. Pai ; Takeshi NishinoChapter 12:
Xanthine Dehydrogenase/Xanthine Oxidase
Picolinate Dehydrogenase
Enzymes of the Xanthine Oxidase Family: the Role of Molybdenum / David J. LoweChapter 13:
The Reactions Catalyzed
Spectroscopic Investigations
Kinetic Studies
Theoretical Calculations
Discussion
The Molybdenum-Containing Hydroxylases of Quinoline, Isoquinoline, and Quinaldine / Reinhard Kappl ; Jurgen HuttermannChapter 14:
Biochemical and Genetic Characterization
Structural Features of Related Enzymes
EPR and ENDOR Characterization of Redox Centers
Molybdenum Enzymes in Reactions Involving Aldehydes and Acids / Maria Joao Romao ; Carlos A. Cunha ; Carlos D. Brondino ; Jose J. G. MouraChapter 15:
Enzymes of the Xanthine Oxidase Family
Enzymes of the Aldehyde Oxidoreductase Family
Molybdenum and Tungsten Enzymes in C1 Metabolism / Julia A. Vorholt ; Rudolf K. ThauerChapter 16:
Formate Dehydrogenase
Formylmethanofuran Dehydrogenase
Carbon Monoxide Dehydrogenase
Formaldehyde Dehydrogenases
Molybdenum Enzymes and Sulfur Metabolism / John H. Enemark ; Michele Mader CosperChapter 17:
Sulfite Oxidase
Dimethyl Sulfoxide Reductase
Biotin Sulfoxide Reductase
Polysulfide Reductase
Comparison of Selenium-Containing Molybdoenzymes / Vadim N. GladyshevChapter 18:
Overview of Selenium-Containing Molybdoenzymes
Incorporation of Selenium into Molybdoenzymes
Selenium Versus Sulfur in Catalysis
Evolution of Selenocysteine-Containing Molybdoenzymes
Tungsten-Dependent Aldehyde Oxidoreductase: A New Family of Enzymes Containing the Pterin Cofactor / Roopali Roy ; Michael W. W. AdamsChapter 19:
Classification of Tungstoenzymes
Aldehyde Ferredoxin Oxidoreductase
Carboxylic Acid Reductase and Aldehyde Dehydrogenase
Formaldehyde Ferredoxin Oxidoreductase
Glyceraldehyde-3-Phosphate Ferredoxin Oxidoreductase
Hypothetical Tungstoenzymes--WOR4 and WOR5
Tungsten Versus Molybdenum in the AOR Family
Tungsten-Substituted Molybdenum Enzymes / C. David Garner ; Lisa J. StewartChapter 20:
Molybdenum and Tungsten Chemistry: Similarities and Differences
Molybdenum and Tungsten Geochemistry and Link to Bioavailability
Early Attempts to Substitute Tungsten for Molybdenum
Molybdenum-Substituted Tungsten Acetylene Hydratase
Molybdenum Metabolism and Requirements in Humans / Judith R. TurnlundChapter 21:
Essentiality of Molybdenum in Humans
Dietary Intake and Bioavailability of Molybdenum
Molybdenum Deficiency and Toxicity
Stable Isotope Studies of Molybdenum Metabolism
Metabolism and Toxicity of Tungsten in Humans and Animals / Florence Lagarde ; Maurice LeroyChapter 22:
Metabolism of Tungsten
Toxicity of Tungsten
Subject Index
Preface to the Series
Preface to Volume 39
In Memoriam of Professor Robert C. Bray
2.

図書

図書
edited by Astrid Sigel, Helmut Sigel and Roland K.O. Sigel
出版情報: Boca Raton, Fla. : Taylor & Francis, 2005  xlv, 301 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 43
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3.

図書

図書
edited by Astrid Sigel, Helmut Sigel and Roland K.O. Sigel
出版情報: Boca Raton, Fla. : Taylor & Francis, 2005  xlv, 298 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 44
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4.

図書

図書
edited by Astrid Sigel, Helmut Sigel, and Roland K.O. Sigel
出版情報: Cambridge, UK : Royal Society of Chemistry, c2011  xxxi, 422 p. ; 24 cm
シリーズ名: Metal ions in life sciences ; v. 8
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Historical Development and Perspectives of the Series
Preface to Volume 8
Contributors to Volume 8
Titles of Volumes 1-44 in the Metal Ions in Biological Systems Series
Contents of Volumes in the Metal Ions in Life Sciences Series
Understanding Combined Effects for Metal Co-Exposure in Ecotoxicology / Rolf Altenburger1:
Abstract
Ecotoxicity from Mixture Exposure
Combination Effect Analysis / 2:
Interactions During Exposure / 3:
Joint Action in Toxicodynamics / 4:
Interaction with Organic Compounds / 5:
Outlook / 6:
Acknowledgments
Abbreviations
References
Human Risk Assessment of Heavy Metals: Principles and Applications / Jean-Lou C. M. Dorne ; George E. N. Kass ; Luisa R. Bordajandi ; Billy Amzal ; Ulla Bertelsen ; Anna F. Castoldi ; Claudia Heppner ; Mari Eskola ; Stefan Fabiansson ; Pietro Ferrari ; Elena Scaravelli ; Eugenia Dogliotti ; Peter Fuerst ; Alan R. Boobis ; Philippe Verger
Introduction
Principles of Chemical Risk Assessment
Toxicology of Heavy Metals
Analytical Techniques and Exposure Assessment of Heavy Metals
Applications to the Human Risk Assessment of Heavy Metals and Metalloids
Conclusions and Future Perspectives
Abbreviations and Definitions
Mixtures and Their Risk Assessment in Toxicology / Moiz M. Mumtaz ; Hugh Hansen ; Hana R. Pohl
Predictions of Toxicity Outcomes
Weight-of-Evidence Evaluations
Experimental Validations
Conclusion
Metal Ions Affecting the Pulmonary and Cardiovascular Systems / Massino Corradi ; Antonio Mutti
Aluminum
Arsenic
Beryllium
Copper
Cadmium
Chromium / 7:
Cobalt / 8:
Lead / 9:
Manganese / 10:
Nickel / 11:
Zinc / 12:
Concluding Remarks / 13:
Metal Ions Affecting the Gastrointestinal System Including the Liver / Declan P. Naughton ; Tamás Nepusz ; Andrea Petroczi
Exposure to Metal Ions in the Gastrointestinal Tract and Liver
Estimation of Toxicity Associated with Metal Ions in the Gastrointestinal Tract and Liver
Metal Ion-Molecular Interactions: Effects on Oxidative Damage
Concluding Remarks and Future Directions
Metal Ions Affecting the Kidney / Bruce A. Fowler
Exposure to Metal Ions in Air, Food, and Water
Transport of Metals/Metalloids in the Circulation
Mechanisms of Metal and Metalloid Uptake by the Kidney
Effects of Metals/Metalloids on the Kidney
Mechanisms of Renal Cell Injury
Renal Biomarkers
Metal/Metalloid Interactions in the Kidney
Metal Ions Affecting the Hematological System / Nickolette Roney ; Henry G. Abadin ; Bruce Fowler
Exposure to Metals and Their Mixtures
Metals Affecting the Hematological System
Binary Interactions of Metals and Hematological Effects
Interaction of Metals with other Chemicals
Conclusions
Metal Ions Affecting the Immune System / Irina Lehmann ; Ulrich Sack ; Jörg Lehmann
Immunotoxicity and Immunomodulation
Effect of Heavy Metals on Innate Immunity
Effect of Heavy Metals on Adaptive Immunity
Mechanisms of Heavy Metal-Induced Immunotoxic/Immunomodulatory Effects
Influence of Heavy Metals on the Resistance Toward Infections
Chronic Inflammation and Autoimmunity
Metal Ions Affecting the Skin and Eyes / Alan B. G. Lansdown
Metal Ions and Metal Ion Gradients in the Physiology and Homeostasis of Mammalian Skin
Xenobiotic Metal Ions
Carcinogenicity of Metal Ions in the Skin
The Eye
General Conclusions
Metal Ions Affecting the Neurological System
Metals Affecting the Neurological System
Interaction of Metals and Neurological Effects
Interactions of Metals with Other Chemicals
Metal Ions Affecting Reproduction and Development / Pietro Apostoli ; Simona Catalani
Time and Duration of Exposure
Mechanisms of Action
Reproductive Effects
Abortions and Other Pregnancy Effects
Prenatal Exposure and Developmental Effects
Early Postnatal Exposure and Developmental Effects
Concluding Remarks and Needs for Further Research
Are Cadmium and Other Heavy Metal Compounds Acting as Endocrine Disrupters? / Andreas Kortenkamp
A Model for Estrogen Receptor Activation by Cadmium
Cadmium Exposure and Cancer Risks in Endocrine-Sensitive Tissues
In Vivo Studies of Estrogenic Effects of Cadmium
Cadmium and Other Heavy Metals in In Vitro Cell-Based Assays of Estrogenicity
Weight of Evidence and Implications for Human Risk Assessment
Genotoxicity of Metal Ions: Chemical Insights / Wojciech Bal ; Anna Maria Protas ; Kazimierz S. Kasprzak
Overview of Chemical and Biochemical Processes Leading to Genotoxic Lesions
Mechanisms of Metal Ion Genotoxicity
Genotoxic Properties of Selected Metals
Critical Overview of the Experimental Methods for Studying the Genotoxic Potential of Metals
Metal Ions in Human Cancer Development / Erik J. Tokar ; Lamia Benbrahim-Tallaa ; Michael P. Waalkes14:
Known Human Metallic Carcinogens
Probable and Possible Metallic Carcinogens
Potential Mechanisms of Metallic Carcinogens
Periods of Particular Sensitivity to Inorganic Carcinogens
Future Issues in Metal Carcinogenesis
Subject Index
Historical Development and Perspectives of the Series
Preface to Volume 8
Contributors to Volume 8
5.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : M. Dekker, c1999  xlvii, 797 p. ; ill. : 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 36
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Preface to the Series
Preface to Volume 36
Contributors
Contents of Previous Volumes
Handbook on Toxicity of Inorganic Compounds
Handbook on Metals in Clinical and Analytical Chemistry
The Mechanism of "Fenton-Like" Reactions and Their Importance for Biological Systems. A Biologist's View / Stefan I. LiochevChapter 1:
Introduction / 1.:
The Fenton Reaction and Fenton-Like Reactions / 2.:
Significance of the Fenton-Like Reactions in vivo / 3.:
Conclusions / 4.:
Acknowledgments
Abbreviations
References
Reactions of Aliphatic Carbon-Centered and Aliphatic-Peroxyl Radicals with Transitionmetal Complexes as a Plausible Source for Biological Damage Induced by Radical Processes / Dan MeyersteinChapter 2:
Sources of Radicals in Biological Systems
Redox Properties of Alkyl and Alkyl-Peroxyl Radicals
The Role of Transition Metal Complexes in Radical-Induced Biological Deleterious Processes
The "Site-Specific" Mechanism / 5.:
Reactions of Aliphatic Carbon-Centered Radicals with Transition Metal Complexes in Aqueous Solutions / 6.:
Mechanisms of Decomposition of the Transient Complexes, L[subscript m]M[superscript n+1]-R / 7.:
Reactions of Alkyl-Peroxyl Radicals with Transition Metal Complexes in Aqueous Solution / 8.:
Mechanisms of Decomposition of the Transient Complexes, L[subscript m]M[superscript n+1]-OOR / 9.:
Concluding Remarks / 10.:
Free Radicals as a Result of Dioxygen Metabolism / Bruce P. BranchaudChapter 3:
Redox Chemistry, Acid-Base Chemistry and Bond Energies of Dioxygen and Reactive Oxygen Species
Major Radical Reactions of Dioxygen and Reactive Oxygen Species
Lipid Peroxidation, an Especially Facile and Major Type of Radical Chain Autoxidation
Lipid Hydroperoxides as a Major Source of Radicals
Production of Reactive Oxygen Species by Respiratory Burst of Phagocytes
Free Radicals as a Source of Uncommon Oxidation States of Transition Metals / George V. Buxton ; Quinto G. Mulazzani7:
Properties of Free Radicals
Generation of Free Radicals
Measurement of Reaction Rates
Interaction of Free Radicals with Simple Transition Metal Ions
Interaction of Free Radicals with Complexed Transition Metal Ions
Biological Chemistry of Copper-Zinc Superoxide Dismutase and Its Link to Amyotrophic Lateral Sclerosis / Thomas J. Lyons ; Edith Butler Gralla ; Joan Selverstone ValentineChapter 5:
Biophysical Properties of Wild-Type Superoxide Dismutase
Enzymatic Activity
Evidence Concerning Biological Function
Role of Mutant Human CuZn Superoxide Dismutase in Amyotrophic Lateral Sclerosis
DNA Damage Mediated by Metal Ions with Special Reference to Copper and Iron / Jose-Luis SagripantiChapter 6:
Binding of Metal Ions to DNA
DNA Lesions
Biological Implications of Metal-DNA Damage
Conclusion
Radical Migration Through the DNA Helix: Chemistry at a Distance / Shana O. Kelley ; Jacqueline K. BartonChapter 7:
Charge Transport in DNA: Chemical and Biological History
DNA as a Bridge for Long-Range Charge Transport
DNA as a Reactant in Long-Range Charge Transfer Reactions
Involvement of Metal Ions in Lipid Peroxidation: Biological Implications / Odile Sergent ; Isabelle Morel ; Josiane CillardChapter 8:
Outline of the Mechanism of Lipid Peroxidation
Involvement of Metal Ions in Various Stages of the Lipid Peroxidation Process
Biological Examinations of the Effect of Metal Ions on Lipid Peroxidation
Considerations on Tissue Damage
Formation of Methemoglobin and Free Radicals in Erythrocytes / Hans Nohl ; Klaus StolzeChapter 9:
ESR Detection of Free Radical Intermediates
Chemiluminescence Detection of the Ferryl Hemoglobin Protein Radical
Spin Labeling of the Erythrocyte Membrane
Iron Liberation
Reactions Involving Thiol Groups (R-SH)
Electrophoresis of Membranes with SDS-PAGE
Role of Free Radicals and Metal Ions in the Pathogenesis of Alzheimer's Disease / Craig S. Atwood ; Xudong Huang ; Robert D. Moir ; Rudolph E. Tanzi ; Ashley I. BushChapter 10:
Normal Cerebral Transition Metal Ion Homeostasis and Oxidative Metabolism
Altered Cerebral Metal Ion and Oxidative Metabolism in Alzheimer's Disease
Cerebral Amyloid Deposition in Neurological Diseases and Aging
Neurochemical Factors that Precipitate Alzheimer A[beta] Protein
Sources of Neuronal Free Radicals
Neurochemical Environments Leading to Amyloid Deposition and Neuronal Death in Alzheimer's Disease
Metal Binding and Radical Generation of Proteins in Human Neurological Diseases and Aging / Gerd Multhaup ; Colin L. MastersChapter 11:
Introduction: Transition Metal Ions in Biological Systems
Free Radicals and Human Diseases
Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis: A Gain of Function
Radical Generation of Amyloid Precursor Protein in Alzheimer's Disease
Involvement of Oxygen Radicals in A[beta] Amyloid Formation
Oxidative Stress and Antioxidants
Thiyl Radicals in Biochemically Important Thiols in the Presence of Metal Ions / Hans-Jurgen Hartmann ; Christian Sievers ; Ulrich WeserChapter 12:
Thiyl Radicals
Thiyl Radicals in the Presence of Iron, Cobalt, Nickel, Manganese, Chromium, and Vanadium
Copper(I)-Stabilized Thiyl Radicals
Improved Stabilization of Copper(I)-Thiyl Radicals Embedded in Inorganic and Biological Matrices
Methylmercury-Induced Generation of Free Radicals: Biological Implications / Theodore A. SarafianChapter 13:
Introduction: The Toxicity and Pathology of Mercury
Mercury Chemistry
Mercurial-Induced Oxidative Stress in Biological Systems
Protective Mechanisms Against Mercury Toxicity
Biological Implications
Role of Free Radicals in Metal-Induced Carcinogenesis / Joseph R. LandolphChapter 14:
The Role of Free Radicals in Chromium Carcinogenesis
The Role of Free Radicals in Nickel Carcinogenesis
The Possible Role of Free Radicals in Arsenic Carcinogenesis
Beryllium Pulmonary Fibrosis and Carcinogenesis: Is There a Role for Free Radicals?
Iron and Free Radicals: Is There a Role in Carcinogenesis or Tumor Promotion?
Copper and Free Radicals: Is There a Role in Carcinogenesis?
pH-Dependent Organocobalt Sources for Active Radical Species: a New Type of Anticancer Agents / Mark E. Vol'pin ; Ilia Ya. Levitin ; Sergei P. OsinskyChapter 15:
Introduction: Prerequisites for the Search for Potential Anticancer Drugs Among Organocobalt Complexes
Alkylcobalt(III) Chelates with Tridentate Schiff Bases
Biomedical Examinations
Conclusion and Outlook
Detection of Chromatin-Associated Hydroxyl Radicals Generated by DNA-Bound Metal Compounds and Antitumor Antibiotics / G. Mike MakrigiorgosChapter 16:
Chromatin-Associated Hydroxyl Radicals
Detection of Chromatin-Associated Hydroxyl Radicals
Methods for Attaching SECCA to In Vitro Chromatin Models
Metal Compounds and Antitumor Antibiotics that Generate Chromatin-Associated HO
Nitric Oxide (No): Formation and Biological Roles in Mammalian Systems / Jon M. Fukuto ; David A. WinkChapter 17:
Biologically Relevant Chemistry of Nitric Oxide
Nitric Oxide Biosynthesis
Physiology and Pathophysiology of Nitric Oxide: A Chemical Perspective
Chemistry of Peroxynitrite and Its Relevance to Biological Systems / Willem H. KoppenolChapter 18:
Introduction and Brief Historical Overview
Is Peroxynitrite Formed in vivo?
Syntheses
Properties, Isomerization, and Decomposition
Reactions that Are First Order in Peroxynitrous Acid
Biomolecular Reactions
Superoxide Dismutase and Peroxynitrite
Peroxynitrite or Hydroxyl Radical?
Note Added in Proof
Novel Nitric Oxide-Liberating Heme Proteins from the Saliva of Bloodsucking Insects / F. Ann Walker ; Jose M. C. Ribeiro ; William R. MontfortChapter 19:
Strategies Used by Bloodsucking Insects to Ensure that They Obtain a Sufficient Blood Meal
Properties of Nitric Oxide
Spectroscopy of the Nitrophorins of Rhodnius prolixus in Comparison to Other Heme Proteins
Redox Chemistry of Nitric Oxide-Heme Systems and the Nitrophorins of Rhodnius prolixus
X-Ray Crystallography
Other Metal-Nitric Oxide Complexes of Importance in Inorganic Chemistry and Biochemistry
Summary
Nitrogen Monoxide-Related Disease and Nitrogen Monoxide Scavengers as Potential Drugs / Simon P. FrickerChapter 20:
Nitric Oxide and Disease
Therapeutic Strategies
Organic Molecules as Nitric Oxide Scavengers
Inorganic Molecules as Scavengers
Ruthenium Complexes
Therapeutics of Nitric Oxide Modulation / Ho-Leung Fung ; Brian P. Booth ; Mohammad Tabrizi-FardChapter 21:
Diversity of Molecular Forms of Nitric Oxide
Interactions Between Nitric Oxide and Calcitonin-Gene Related Peptide (CGRP)
Therapeutics of Nitric Oxide Enhancement
Therapeutics of Nitric Oxide Inhibition
Subject Index
Preface to the Series
Preface to Volume 36
Contributors
6.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : M. Dekker, c2000  xlvi, 761 p. ; ill. : 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 37
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Preface to the Series
Preface to Volume 37
Contributors
Contents of Previous Volumes
Handbook on Toxicity of Inorganic Compounds
Handbook on Metals in Clinical and Analytical Chemistry
Manganese in Natural Waters and Earth's Crust: Its Availability to Organisms / James J. MorganChapter 1:
Introduction / 1.:
Chemical Properties / 2.:
Rates of Manganese Reactions in Water / 3.:
Manganese Profiles in the Oceans / 4.:
Freshwaters / 5.:
Concluding Remarks / 6.:
Acknowledgments
References
Manganese Transport in Microorganisms / Valeria Cizewski CulottaChapter 2:
Introduction and Overview
Biochemical Studies in Bacteria
Genes Controlling Manganese Accumulation in Bacteria
Genes Controlling Manganese Accumulation in Yeast
Genes Controlling the Intracellular Transport and Trafficking of Manganese Ions in Yeast
Conclusions and Directions for the Future
Abbreviations
Manganese Uptake and Transport in Plants / Zdenko RengelChapter 3:
Availability of Manganese in the Rhizosphere
Uptake of Manganese by Plant Cells
Transport of Manganese in Xylem and Phloem
Loading of Manganese into Developing Grain
Genotypic Differences in Manganese Uptake and Utilization
Conclusions / 7.:
Manganese Metabolism in Animals and Humans Including the Toxicity of Manganese / Carl L. Keen ; Jodi L. Ensunsa ; Michael S. CleggChapter 4:
Chemical and Physical Properties
Analysis
Physiological Role
Manganese Deficiency
Manganese Toxicity
Assessment of Manganese Status
Summary and Future Directions / 8.:
Acknowledgment
Interrelations Between Manganese and Other Metal Ions in Health and Disease / James C. K. Lai ; Margaret J. Minski ; Alex W. K. Chan ; Louis LimChapter 5:
Interdependence Between Manganese and Other Metals in Absorption
Interrelations Between Manganese and Other Metals in Peripheral Organs
Interrelations Between Manganese and Other Metals in Brain
Interrelations Between Manganese and Other Metals in Brain in Human Health and Diseases
Conclusions and Prospects for Future Studies
The Use of Manganese as a Probe for Elucidating the Role of Magnesium Ions in Ribozymes / Andrew L. FeigChapter 6:
Use of Mn[superscript 2+] in Biochemical Studies of Phosphorothioate-Containing Ribozymes
Use of Mn[superscript 2+] in Crystallographic Experiments to Find Mg[superscript 2+] Binding Sites
Use of Mn[superscript 2+] in Magnetic Resonance Experiments to Study Metal Binding Sites
Mn[superscript 2+] as a Probe of Divalent Metal Ion Binding and Function in Enzymes and Other Proteins / George H. Reed ; Russell R. PoynerChapter 7:
Survey of Coordination Properties and Tendencies
CW EPR Properties
Ligand Superhyperfine Splittings and Structure Determinations
ENDOR and ESEEM Methods
Electron Spin-Spin Coupling and Multinuclear Metal Centers
Enzymes and Proteins Containing Manganese: an Overview / James D. Crowley ; Deborah A. Traynor ; David C. WeatherburnChapter 8:
Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases
Proteins Containing Bound Manganese
Manganese(II) in Concanavalin a and Other Lectin Proteins / A. Joseph Kalb(Gilboa) ; Jarjis Habash ; Nicola S. Hunter ; Helen J. Price ; James Raftery ; John R. Helliwell9.:
Introduction: The Biology and Molecular Biology of Concanavalin A
Isolation and Characterization
Spectroscopic Studies
Crystals of Concanavalin A: Introduction and Early History
Ultrahigh-Resolution X-Ray Protein Crystallography
Manganese Multiwavelength Anomalous Dispersion Protein Crystallography
Neutron Laue Diffraction
Role of Manganese in Saccharide Binding in Concanavalin A and Other Legume Lectins
Manganese-Activated Phosphatases / Frank RusnakChapter 10:
Introduction: Phosphate Esters in Biological Systems
Classification of Metal-Activated Phosphatases
Phosphatase Structure and Active Site Metal Ion Geometry
Mechanisms of Hydrolysis
Manganese(II) as a Probe for the Mechanism and Specificity of Restriction Endonucleases / Geoffrey S. Baldwin ; Niall A. Gormely ; Stephen E. HalfordChapter 11:
DNA Recognition and Cleavage
Restriction Endonucleases with Manganese
Abbreviations and Definitions
Role of the Binuclear Manganese(II) Site in Xylose Isomerase / Ralf Bogumil ; Reinhard Kappl ; Jurgen HuttermannChapter 12:
X-Ray Crystal Structures of Xylose Isomerase
The Two Metal Binding Sites
EPR Studies on Manganese-Substituted Xylose Isomerase
The Catalytic Mechanism and the Role of the Binuclear Center
Arginase: a Binuclear Manganese Metalloenzyme / David E. Ash ; J. David Cox ; David W. ChristiansonChapter 13:
Enzymology and Bioinorganic Chemistry
Arginase Structure and Mechanism
Related Binuclear Manganese Metalloenzymes
The Use of Model Complexes to Elucidate The Structure and Function of Manganese Redox Enzymes / Vincent L. Pecoraro ; Wen-Yuan HsiehChapter 14:
Manganese Catalases
The Oxygen Evolving Complex
The Energetics of Water Oxidation and the Role of Protons
Toward a Unified View of Biological Water Oxidation Chemistry
Conclusion
Manganese(II)-Dependent Extradiol-Cleaving Catechol Dioxygenases / Lawrence Que, Jr. ; Mark F. ReynoldsChapter 15:
The Intradiol Cleavage Precedent
Fe(II)-Dependent Extradiol-Cleaving Dioxygenases
Mn(II)-Dependent Dioxygenases
Reactivity / Derek W. Yoder ; Jungwon Hwang ; James E. Penner-HahnChapter 16:
Spectroscopy
Structural Characterization
Mechanism
Manganese Peroxidase / Michael H. Gold ; Heather L. Youngs ; Maarten D. Sollewijn GelpkeChapter 17:
General Properties of Mn Peroxidase
Reactions Catalyzed by Mn Peroxidase
Biophysical Studies of Mn Peroxidase
Mn Peroxidase cDNA and Genomic Sequences
Crystal Structure of Mn Peroxidase
Structure-Function Studies of Mn Peroxidase
Regulation of Mn Peroxidase Gene Expression
Manganese Superoxide Dismutase / James W. WhittakerChapter 18:
Molecular Structure
Ligand Interactions
Mutagenic Dissection of the Active Site
Metal Specificity: The Irony of Mn Superoxide Dismutase
Superoxide Dismutase as a One-Electron Redox Engine
Mechanistic Aspects of the Tyrosyl Radical-Manganese Complex in Photosynthetic Water Oxidation / Curtis W. Hoganson ; Gerald T. BabcockChapter 19:
Structure of the Catalytic Site
Water Binding and Exchange
Proton Release
Mechanisms for Oxygen Production
The Nature of S-State Cycle Intermediates
The Polypeptides of Photosystem II and Their Influence on Manganotyrosyl-Based Oxygen Evolution / Richard J. DebusChapter 20:
The Polypeptides of Photosystem II
The Environments of the Redox-Active Tyrosine Residues
The Environment of the Manganese Cluster
Subject Index
Preface to the Series
Preface to Volume 37
Contributors
7.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, 1998  xlii, 775 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 35
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Biological cycling of iron in the sea
microbial iron transport - iron acquisition by pathogenic microorganisms
bacterial iron transport - mechanisms, genetics and regulation
molecular biology of iron transport in fungi
soil microorganisms and iron uptake by higher plants
iron transport in gaminaceous plants
the coordination chemistry of siderophores - thermodynamics and kinetics of iron chelation and release
biomimetic siderophores - from structural probes to diagnostic tools
Biological cycling of iron in the sea
microbial iron transport - iron acquisition by pathogenic microorganisms
bacterial iron transport - mechanisms, genetics and regulation
8.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c1996  xli, 678 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 33
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Molecular modelling of transition metal adducts with nucleic acids and their constituents
zinc complexes as targeting agents for nucleic acids
metallocene interactions with DNA and DNA processing enzymes
evidences for a catalytic activity of the DNA double helix in the reactions between DNA, platinum (II) and intercalators
trans-diammineplatinum (II) - what makes it different from CIS-DDP?
coordination chemistry of a neglected relative of cisplatin and its interaction with nucleic
Molecular modelling of transition metal adducts with nucleic acids and their constituents
zinc complexes as targeting agents for nucleic acids
metallocene interactions with DNA and DNA processing enzymes
9.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c2003  lvii, 799 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 40
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10.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c2004  liii, 519 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 41
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Speciation Dependent Intake and Uptake of Essential Elements
Magnesium in Human Therapy
Calcium Status and Supplementation
Zinc Deficiency: Its Characteristics and Treatment
The Use and Role of Zinc and Its Compounds in Wound Healing
Iron Chelators and Their Therapeutic Potential
Vanadium Compounds in the Treatment of Diabetes
Copper and Zinc Complexes as Anti-Inflammatory Drugs
Gold Complexes in the Treatment of Rheumatoid Arthritis
The Medical Use of Lithium
Bismuth in
Speciation Dependent Intake and Uptake of Essential Elements
Magnesium in Human Therapy
Calcium Status and Supplementation
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