Preface |
Abbreviations |
Introduction / 1: |
The Significance of Chirality and Stereoisomeric Discrimination / 1.1: |
Asymmetry / 1.2: |
Conditions for Asymmetry / 1.2.1: |
Nomenclature / 1.2.2: |
Determining Enantiomer Composition / 1.3: |
Measuring Specific Rotation / 1.3.1: |
The Nuclear Magnetic Resonance Method / 1.3.2: |
Some Other Reagents for Nuclear Magnetic Resonance Analysis / 1.3.3: |
Determining the Enantiomer Composition of Chiral Glycols or Cyclic Ketones / 1.3.4: |
Chromatographic Methods Using Chiral Columns / 1.3.5: |
Capillary Electrophoresis with Enantioselective Supporting Electrolytes / 1.3.6: |
Determining Absolute Configuration / 1.4: |
X-Ray Diffraction Methods / 1.4.1: |
Chiroptical Methods / 1.4.2: |
The Chemical Interrelation Method / 1.4.3: |
Prelog's Method / 1.4.4: |
Horeau's Method / 1.4.5: |
Nuclear Magnetic Resonance Method for Relative Configuration Determination / 1.4.6: |
General Strategies for Asymmetric Synthesis / 1.5: |
"Chiron" Approaches / 1.5.1: |
Acyclic Diastereoselective Approaches / 1.5.2: |
Double Asymmetric Synthesis / 1.5.3: |
Examples of Some Complicated Compounds / 1.6: |
Some Common Definitions in Asymmetric Synthesis and Stereochemistry / 1.7: |
References / 1.8: |
[alpha]-Alkylation and Catalytic Alkylation of Carbonyl Compounds / 2: |
Chirality Transfer / 2.1: |
Intra-annular Chirality Transfer / 2.2.1: |
Extra-annular Chirality Transfer / 2.2.2: |
Chelation-Enforced Intra-annular Chirality Transfer / 2.2.3: |
Preparation of Quaternary Carbon Centers / 2.3: |
Preparation of [alpha]-Amino Acids / 2.4: |
Nucleophilic Substitution of Chiral Acetal / 2.5: |
Chiral Catalyst-Induced Aldehyde Alkylation: Asymmetric Nucleophilic Addition / 2.6: |
Catalytic Asymmetric Additions of Dialkylzinc to Ketones: Enantioselective Formation of Tertiary Alcohols / 2.7: |
Asymmetric Cyanohydrination / 2.8: |
Asymmetric [alpha]-Hydroxyphosphonylation / 2.9: |
Summary / 2.10: |
Aldol and Related Reactions / 2.11: |
Substrate-Controlled Aldol Reaction / 3.1: |
Oxazolidones as Chiral Auxiliaries: Chiral Auxiliary-Mediated Aldol-Type Reactions / 3.2.1: |
Pyrrolidines as Chiral Auxiliaries / 3.2.2: |
Aminoalcohols as the Chiral Auxiliaries / 3.2.3: |
Acylsultam Systems as the Chiral Auxiliaries / 3.2.4: |
[alpha]-Silyl Ketones / 3.2.5: |
Reagent-Controlled Aldol Reactions / 3.3: |
Aldol Condensations Induced by Chiral Boron Compounds / 3.3.1: |
Aldol Reactions Controlled by Corey's Reagents / 3.3.2: |
Aldol Condensations Controlled by Miscellaneous Reagents / 3.3.3: |
Chiral Catalyst-Controlled Asymmetric Aldol Reaction / 3.4: |
Mukaiyama's System / 3.4.1: |
Asymmetric Aldol Reactions with a Chiral Ferrocenylphosphine-Gold(I) Complex / 3.4.2: |
Asymmetric Aldol Reactions Catalyzed by Chiral Lewis Acids / 3.4.3: |
Catalytic Asymmetric Aldol Reaction Promoted by Bimetallic Catalysts: Shibasaki's System / 3.4.4: |
Double Asymmetric Aldol Reactions / 3.5: |
Asymmetric Allylation Reactions / 3.6: |
The Roush Reaction / 3.6.1: |
The Corey Reaction / 3.6.2: |
Other Catalytic Asymmetric Allylation Reactions / 3.6.3: |
Asymmetric Allylation and Alkylation of Imines / 3.7: |
Other Types of Addition Reactions: Henry Reaction / 3.8: |
Asymmetric Oxidations / 3.9: |
Asymmetric Epoxidation of Allylic Alcohols: Sharpless Epoxidation / 4.1: |
The Characteristics of Sharpless Epoxidation / 4.1.1: |
Mechanism / 4.1.2: |
Modifications and Improvements of Sharpless Epoxidation / 4.1.3: |
Selective Opening of 2,3-Epoxy Alcohols / 4.2: |
External Nucleophilic Opening of 2,3-Epoxy Alcohols / 4.2.1: |
Opening by Intramolecular Nucleophiles / 4.2.2: |
Opening by Metallic Hydride Reagents / 4.2.3: |
Opening by Organometallic Compounds / 4.2.4: |
Payne Rearrangement and Ring-Opening Processes / 4.2.5: |
Asymmetric Desymmetrization of meso-Epoxides / 4.2.6: |
Asymmetric Epoxidation of Symmetric Divinyl Carbinols / 4.3: |
Enantioselective Dihydroxylation of Olefins / 4.4: |
Asymmetric Aminohydroxylation / 4.5: |
Epoxidation of Unfunctionalized Olefins / 4.6: |
Catalytic Enantioselective Epoxidation of Simple Olefins by Salen Complexes / 4.6.1: |
Catalytic Enantioselective Epoxidation of Simple Olefins by Porphyrin Complexes / 4.6.2: |
Chiral Ketone-Catalyzed Asymmetric Oxidation of Unfunctionalized Olefins / 4.6.3: |
Catalytic Asymmetric Epoxidation of Aldehydes / 4.7: |
Asymmetric Oxidation of Enolates for the Preparation of Optically Active [alpha]-Hydroxyl Carbonyl Compounds / 4.8: |
Substrate-Controlled Reactions / 4.8.1: |
Reagent-Controlled Reactions / 4.8.2: |
Asymmetric Aziridination and Related Reactions / 4.9: |
Asymmetric Aziridination / 4.9.1: |
Regioselective Ring Opening of Aziridines / 4.9.2: |
Asymmetric Diels-Alder and Other Cyclization Reactions / 4.10: |
Chiral Dienophiles / 5.1: |
Acrylate / 5.1.1: |
[alpha], [beta]-Unsaturated Ketone / 5.1.2: |
Chiral [alpha], [beta]-Unsubstituted N-Acyloxazolidinones / 5.1.3: |
Chiral Alkoxy Iminium Salt / 5.1.4: |
Chiral Sulfinyl-Substituted Compounds as Dienophiles / 5.1.5: |
Chiral Dienes / 5.2: |
Double Asymmetric Cycloaddition / 5.3: |
Chiral Lewis Acid Catalysts / 5.4: |
Narasaka's Catalyst / 5.4.1: |
Chiral Lanthanide Catalyst / 5.4.2: |
Bissulfonamides (Corey's Catalyst) / 5.4.3: |
Chiral Acyloxy Borane Catalysts / 5.4.4: |
Bronsted Acid-Assisted Chiral Lewis Acid Catalysts / 5.4.5: |
Bis(Oxazoline) Catalysts / 5.4.6: |
Amino Acid Salts as Lewis Acids for Asymmetric Diels-Alder Reactions / 5.4.7: |
Hetero Diels-Alder Reactions / 5.5: |
Oxo Diels-Alder Reactions / 5.5.1: |
Aza Diels-Alder Reactions / 5.5.2: |
Formation of Quaternary Stereocenters Through Diels-Alder Reactions / 5.6: |
Intramolecular Diels-Alder Reactions / 5.7: |
Retro Diels-Alder Reactions / 5.8: |
Asymmetric Dipolar Cycloaddition / 5.9: |
Asymmetric Cyclopropanation / 5.10: |
Transition Metal Complex-Catalyzed Cyclopropanations / 5.10.1: |
The Catalytic Asymmetric Simmons-Smith Reaction / 5.10.2: |
Asymmetric Catalytic Hydrogenation and Other Reduction Reactions / 5.11: |
Chiral Phosphine Ligands for Homogeneous Asymmetric Catalytic Hydrogenation / 6.1: |
Asymmetric Catalytic Hydrogenation of C=C Bonds / 6.1.2: |
Asymmetric Reduction of Carbonyl Compounds / 6.2: |
Reduction by BINAL-H / 6.2.1: |
Transition Metal-Complex Catalyzed Hydrogenation of Carbonyl Compounds / 6.2.2: |
The Oxazaborolidine Catalyst System / 6.2.3: |
Asymmetric Reduction of Imines / 6.3: |
Asymmetric Transfer Hydrogenation / 6.4: |
Asymmetric Hydroformylation / 6.5: |
Applications of Asymmetric Reactions in the Synthesis of Natural Products / 6.6: |
The Synthesis of Erythronolide A / 7.1: |
The Synthesis of 6-Deoxyerythronolide / 7.2: |
The Synthesis of Rifamycin S / 7.3: |
Kishi's Synthesis in 1980 / 7.3.1: |
Kishi's Synthesis in 1981 / 7.3.2: |
Masamune's Synthesis / 7.3.3: |
The Synthesis of Prostaglandins / 7.4: |
Three-Component Coupling / 7.4.1: |
Synthesis of the [omega]-Side Chain / 7.4.2: |
The Enantioselective Synthesis of (R)-4-Hydroxy-2-Cyclopentenone / 7.4.3: |
The Total Synthesis of Taxol--A Challenge and Opportunity for Chemists Working in the Area of Asymmetric Synthesis / 7.5: |
Synthesis of Baccatin III, the Polycyclic Part of Taxol / 7.5.1: |
Asymmetric Synthesis of the Taxol Side Chain / 7.5.2: |
Enzymatic Reactions and Miscellaneous Asymmetric Syntheses / 7.6: |
Enzymatic and Related Processes / 8.1: |
Lipase/Esterase-Catalyzed Reactions / 8.1.1: |
Reductions / 8.1.2: |
Enantioselective Microbial Oxidation / 8.1.3: |
Formation of C-C Bond / 8.1.4: |
Biocatalysts from Cultured Plant Cells / 8.1.5: |
Miscellaneous Methods / 8.2: |
Asymmetric Synthesis Catalyzed by Chiral Ferrocenylphosphine Complex / 8.2.1: |
Asymmetric Hydrosilylation of Olefins / 8.2.2: |
Synthesis of Chiral Biaryls / 8.2.3: |
The Asymmetric Kharasch Reaction / 8.2.4: |
Optically Active Lactones from Metal-Catalyzed Baeyer-Villiger-Type Oxidations Using Molecular Oxygen as the Oxidant / 8.2.5: |
Recent Progress in Asymmetric Wittig-Type Reactions / 8.2.6: |
Asymmetric Reformatsky Reactions / 8.2.7: |
Catalytic Asymmetric Wacker Cyclization / 8.2.8: |
Palladium-Catalyzed Asymmetric Alkenylation of Cyclic Olefins / 8.2.9: |
Intramolecular Enyne Cyclization / 8.2.10: |
Asymmetric Darzens Reaction / 8.2.11: |
Asymmetric Conjugate Addition / 8.2.12: |
Asymmetric Synthesis of Fluorinated Compounds / 8.2.13: |
New Concepts in Asymmetric Reaction / 8.3: |
Ti Catalysts from Self-Assembly Components / 8.3.1: |
Desymmetrization / 8.3.2: |
Cooperative Asymmetric Catalysis / 8.3.3: |
Stereochemical Nonlinear Effects in Asymmetric Reaction / 8.3.4: |
Chiral Poisoning / 8.3.5: |
Enantioselective Activation and Induced Chirality / 8.3.6: |
Chiral Amplification, Chiral Autocatalysis, and the Origin of Natural Chirality / 8.4: |
Index / 8.5: |