Preface |
Note to the reader |
Glossary |
Chemiosmotic Energy Transduction / 1: |
Introduction / 1.1: |
The chemiosmotic theory: fundamentals / 1.2: |
The basic morphology of energy-transducing membranes / 1.3: |
Overview / 1.4: |
Ion Transport Across Energy-Conserving Membranes / 2: |
The classification of ion transport / 2.1: |
Bilayer-mediated transport / 2.3: |
Protein-catalysed transport / 2.4: |
Swelling and the co-ordinate movement of ions across membranes / 2.5: |
Quantitative Bioenergetics: the Measurement of Driving Forces / 3: |
Gibbs energy and displacement from equilibrium / 3.1: |
Oxidation-reduction (redox) potentials / 3.3: |
Ion electrochemical potential differences / 3.4: |
Photons / 3.5: |
Bioenergetic interconversions and thermodynamic constraints on their stoichiometries / 3.6: |
The equilibrium distributions of ions, weak acids and weak bases / 3.7: |
Membrane potentials, diffusion potentials, Donnan potentials and surface potentials / 3.8: |
The Chemiosmotic Proton Circuit / 4: |
The measurement of protonmotive force / 4.1: |
The stoichiometry of proton extrusion by the respiratory chain / 4.3: |
The stoichiometry of proton uptake by the ATP synthase / 4.4: |
Proton current and respiratory control / 4.5: |
Proton conductance / 4.6: |
Mitochondrial respiration rate and metabolic control analysis / 4.7: |
Overall parameters of energy transduction / 4.8: |
Reversed electron transfer and the proton circuit driven by ATP hydrolysis / 4.9: |
ATP synthesis driven by an artificial protonmotive force / 4.10: |
Kinetic competence of [Delta]p in the proton circuit / 4.11: |
Light-dependent ATP synthesis by bovine heart ATP synthase / 4.12: |
Respiratory Chains / 5: |
Components of the mitochondrial respiratory chain / 5.1: |
The sequence of redox carriers in the respiratory chain / 5.3: |
The mechanism of electron transfer / 5.4: |
Proton translocation by the respiratory chain: 'loops', 'conformation pumps' or both? / 5.5: |
Complex I (NADH-UQ oxidoreductase) / 5.6: |
Delivering electrons to ubiquinone without proton translocation / 5.7: |
Ubiquinone and complex III (bc[subscript 1] or UQ-cyt c oxidoreductase) / 5.8: |
Cytochrome c and complex IV (cytochrome c oxidase; ferrocytochrome c: O[subscript 2] oxidoreductase) / 5.9: |
Overall proton and charge movements catalysed by the respiratory chain: correlation with the P/O ratio / 5.10: |
Superoxide production by complexes I and III / 5.11: |
Oxidative stress / 5.12: |
The nicotinamide nucleotide transhydrogenase / 5.13: |
Electron transport in mitochondria of non-mammalian cells / 5.14: |
Bacterial respiratory chains / 5.15: |
Photosynthetic Generators of Protonmotive Force / 6: |
The light reaction of photosynthesis in Rhodobacter sphaeroides and related organisms / 6.1: |
The generation by illumination or respiration of [Delta]p in photosynthetic bacteria / 6.3: |
The electron-transfer and light-capture pathway in green plants and algae / 6.4: |
Bacteriorhodopsin and halorhodopsin / 6.5: |
The ATP Synthase / 7: |
F[subscript 1] and F[subscript o] / 7.1: |
The subunits of the F[subscript 1].F[subscript o]-ATPase / 7.3: |
The structure of F[subscript 1].F[subscript o] / 7.4: |
Enzymology of ATP synthase / 7.5: |
Relating the structure to function for ATP synthase / 7.6: |
Non-thermodynamic regulation of the ATP synthase / 7.7: |
Proton translocation by other ATPases and pyrophosphatases / 7.8: |
Metabolite and Ion Transport / 8: |
Mitochondrial cation transporters / 8.1: |
Mitochondrial metabolite transporters / 8.3: |
The transfer of electrons from cytoplasmic NADH to the respiratory chain / 8.4: |
The phosphate and adenine nucleotide transporters / 8.5: |
The uncoupling protein family / 8.6: |
Bacterial transport / 8.7: |
Transport (movement) of bacterial cells / 8.8: |
Transport of macromolecules across bacterial membranes / 8.9: |
Mitochondria in the Cell / 9: |
Monitoring [Delta psi subscript m] and ATP synthesis in intact cells / 9.1: |
Mitochondria and cellular Ca[superscript 2+] homeostasis / 9.3: |
Mitochondria and programmed cell death / 9.4: |
Mitochondria and necrotic cell death / 9.5: |
The mitochondrial genome / 9.6: |
Import and assembly of mitochondrial proteins / 9.7: |
Mitochondrial genetic diseases / 9.8: |
Mitochondrial involvement in neurodegenerative diseases / 9.9: |
References |
Protein structures / Appendix: |
Index |