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1.

図書

図書
edited by Hans G. Seiler and Helmut Sigel ; with the assistance of Astrid Sigel
出版情報: New York : Dekker, c1988  xxiv, 1069 p. ; 26 cm
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2.

図書

図書
edited by Helmut Sigel ; with the assistance of Astrid Sigel
出版情報: New York : M. Dekker, c1983  xxv, 397 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 16
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3.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : M. Dekker, c2000  xlvi, 761 p. ; ill. : 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 37
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Preface to the Series
Preface to Volume 37
Contributors
Contents of Previous Volumes
Handbook on Toxicity of Inorganic Compounds
Handbook on Metals in Clinical and Analytical Chemistry
Manganese in Natural Waters and Earth's Crust: Its Availability to Organisms / James J. MorganChapter 1:
Introduction / 1.:
Chemical Properties / 2.:
Rates of Manganese Reactions in Water / 3.:
Manganese Profiles in the Oceans / 4.:
Freshwaters / 5.:
Concluding Remarks / 6.:
Acknowledgments
References
Manganese Transport in Microorganisms / Valeria Cizewski CulottaChapter 2:
Introduction and Overview
Biochemical Studies in Bacteria
Genes Controlling Manganese Accumulation in Bacteria
Genes Controlling Manganese Accumulation in Yeast
Genes Controlling the Intracellular Transport and Trafficking of Manganese Ions in Yeast
Conclusions and Directions for the Future
Abbreviations
Manganese Uptake and Transport in Plants / Zdenko RengelChapter 3:
Availability of Manganese in the Rhizosphere
Uptake of Manganese by Plant Cells
Transport of Manganese in Xylem and Phloem
Loading of Manganese into Developing Grain
Genotypic Differences in Manganese Uptake and Utilization
Conclusions / 7.:
Manganese Metabolism in Animals and Humans Including the Toxicity of Manganese / Carl L. Keen ; Jodi L. Ensunsa ; Michael S. CleggChapter 4:
Chemical and Physical Properties
Analysis
Physiological Role
Manganese Deficiency
Manganese Toxicity
Assessment of Manganese Status
Summary and Future Directions / 8.:
Acknowledgment
Interrelations Between Manganese and Other Metal Ions in Health and Disease / James C. K. Lai ; Margaret J. Minski ; Alex W. K. Chan ; Louis LimChapter 5:
Interdependence Between Manganese and Other Metals in Absorption
Interrelations Between Manganese and Other Metals in Peripheral Organs
Interrelations Between Manganese and Other Metals in Brain
Interrelations Between Manganese and Other Metals in Brain in Human Health and Diseases
Conclusions and Prospects for Future Studies
The Use of Manganese as a Probe for Elucidating the Role of Magnesium Ions in Ribozymes / Andrew L. FeigChapter 6:
Use of Mn[superscript 2+] in Biochemical Studies of Phosphorothioate-Containing Ribozymes
Use of Mn[superscript 2+] in Crystallographic Experiments to Find Mg[superscript 2+] Binding Sites
Use of Mn[superscript 2+] in Magnetic Resonance Experiments to Study Metal Binding Sites
Mn[superscript 2+] as a Probe of Divalent Metal Ion Binding and Function in Enzymes and Other Proteins / George H. Reed ; Russell R. PoynerChapter 7:
Survey of Coordination Properties and Tendencies
CW EPR Properties
Ligand Superhyperfine Splittings and Structure Determinations
ENDOR and ESEEM Methods
Electron Spin-Spin Coupling and Multinuclear Metal Centers
Enzymes and Proteins Containing Manganese: an Overview / James D. Crowley ; Deborah A. Traynor ; David C. WeatherburnChapter 8:
Oxidoreductases
Transferases
Hydrolases
Lyases
Isomerases
Ligases
Proteins Containing Bound Manganese
Manganese(II) in Concanavalin a and Other Lectin Proteins / A. Joseph Kalb(Gilboa) ; Jarjis Habash ; Nicola S. Hunter ; Helen J. Price ; James Raftery ; John R. Helliwell9.:
Introduction: The Biology and Molecular Biology of Concanavalin A
Isolation and Characterization
Spectroscopic Studies
Crystals of Concanavalin A: Introduction and Early History
Ultrahigh-Resolution X-Ray Protein Crystallography
Manganese Multiwavelength Anomalous Dispersion Protein Crystallography
Neutron Laue Diffraction
Role of Manganese in Saccharide Binding in Concanavalin A and Other Legume Lectins
Manganese-Activated Phosphatases / Frank RusnakChapter 10:
Introduction: Phosphate Esters in Biological Systems
Classification of Metal-Activated Phosphatases
Phosphatase Structure and Active Site Metal Ion Geometry
Mechanisms of Hydrolysis
Manganese(II) as a Probe for the Mechanism and Specificity of Restriction Endonucleases / Geoffrey S. Baldwin ; Niall A. Gormely ; Stephen E. HalfordChapter 11:
DNA Recognition and Cleavage
Restriction Endonucleases with Manganese
Abbreviations and Definitions
Role of the Binuclear Manganese(II) Site in Xylose Isomerase / Ralf Bogumil ; Reinhard Kappl ; Jurgen HuttermannChapter 12:
X-Ray Crystal Structures of Xylose Isomerase
The Two Metal Binding Sites
EPR Studies on Manganese-Substituted Xylose Isomerase
The Catalytic Mechanism and the Role of the Binuclear Center
Arginase: a Binuclear Manganese Metalloenzyme / David E. Ash ; J. David Cox ; David W. ChristiansonChapter 13:
Enzymology and Bioinorganic Chemistry
Arginase Structure and Mechanism
Related Binuclear Manganese Metalloenzymes
The Use of Model Complexes to Elucidate The Structure and Function of Manganese Redox Enzymes / Vincent L. Pecoraro ; Wen-Yuan HsiehChapter 14:
Manganese Catalases
The Oxygen Evolving Complex
The Energetics of Water Oxidation and the Role of Protons
Toward a Unified View of Biological Water Oxidation Chemistry
Conclusion
Manganese(II)-Dependent Extradiol-Cleaving Catechol Dioxygenases / Lawrence Que, Jr. ; Mark F. ReynoldsChapter 15:
The Intradiol Cleavage Precedent
Fe(II)-Dependent Extradiol-Cleaving Dioxygenases
Mn(II)-Dependent Dioxygenases
Reactivity / Derek W. Yoder ; Jungwon Hwang ; James E. Penner-HahnChapter 16:
Spectroscopy
Structural Characterization
Mechanism
Manganese Peroxidase / Michael H. Gold ; Heather L. Youngs ; Maarten D. Sollewijn GelpkeChapter 17:
General Properties of Mn Peroxidase
Reactions Catalyzed by Mn Peroxidase
Biophysical Studies of Mn Peroxidase
Mn Peroxidase cDNA and Genomic Sequences
Crystal Structure of Mn Peroxidase
Structure-Function Studies of Mn Peroxidase
Regulation of Mn Peroxidase Gene Expression
Manganese Superoxide Dismutase / James W. WhittakerChapter 18:
Molecular Structure
Ligand Interactions
Mutagenic Dissection of the Active Site
Metal Specificity: The Irony of Mn Superoxide Dismutase
Superoxide Dismutase as a One-Electron Redox Engine
Mechanistic Aspects of the Tyrosyl Radical-Manganese Complex in Photosynthetic Water Oxidation / Curtis W. Hoganson ; Gerald T. BabcockChapter 19:
Structure of the Catalytic Site
Water Binding and Exchange
Proton Release
Mechanisms for Oxygen Production
The Nature of S-State Cycle Intermediates
The Polypeptides of Photosystem II and Their Influence on Manganotyrosyl-Based Oxygen Evolution / Richard J. DebusChapter 20:
The Polypeptides of Photosystem II
The Environments of the Redox-Active Tyrosine Residues
The Environment of the Manganese Cluster
Subject Index
Preface to the Series
Preface to Volume 37
Contributors
4.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : M. Dekker, c1999  xlvii, 797 p. ; ill. : 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 36
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Preface to the Series
Preface to Volume 36
Contributors
Contents of Previous Volumes
Handbook on Toxicity of Inorganic Compounds
Handbook on Metals in Clinical and Analytical Chemistry
The Mechanism of "Fenton-Like" Reactions and Their Importance for Biological Systems. A Biologist's View / Stefan I. LiochevChapter 1:
Introduction / 1.:
The Fenton Reaction and Fenton-Like Reactions / 2.:
Significance of the Fenton-Like Reactions in vivo / 3.:
Conclusions / 4.:
Acknowledgments
Abbreviations
References
Reactions of Aliphatic Carbon-Centered and Aliphatic-Peroxyl Radicals with Transitionmetal Complexes as a Plausible Source for Biological Damage Induced by Radical Processes / Dan MeyersteinChapter 2:
Sources of Radicals in Biological Systems
Redox Properties of Alkyl and Alkyl-Peroxyl Radicals
The Role of Transition Metal Complexes in Radical-Induced Biological Deleterious Processes
The "Site-Specific" Mechanism / 5.:
Reactions of Aliphatic Carbon-Centered Radicals with Transition Metal Complexes in Aqueous Solutions / 6.:
Mechanisms of Decomposition of the Transient Complexes, L[subscript m]M[superscript n+1]-R / 7.:
Reactions of Alkyl-Peroxyl Radicals with Transition Metal Complexes in Aqueous Solution / 8.:
Mechanisms of Decomposition of the Transient Complexes, L[subscript m]M[superscript n+1]-OOR / 9.:
Concluding Remarks / 10.:
Free Radicals as a Result of Dioxygen Metabolism / Bruce P. BranchaudChapter 3:
Redox Chemistry, Acid-Base Chemistry and Bond Energies of Dioxygen and Reactive Oxygen Species
Major Radical Reactions of Dioxygen and Reactive Oxygen Species
Lipid Peroxidation, an Especially Facile and Major Type of Radical Chain Autoxidation
Lipid Hydroperoxides as a Major Source of Radicals
Production of Reactive Oxygen Species by Respiratory Burst of Phagocytes
Free Radicals as a Source of Uncommon Oxidation States of Transition Metals / George V. Buxton ; Quinto G. Mulazzani7:
Properties of Free Radicals
Generation of Free Radicals
Measurement of Reaction Rates
Interaction of Free Radicals with Simple Transition Metal Ions
Interaction of Free Radicals with Complexed Transition Metal Ions
Biological Chemistry of Copper-Zinc Superoxide Dismutase and Its Link to Amyotrophic Lateral Sclerosis / Thomas J. Lyons ; Edith Butler Gralla ; Joan Selverstone ValentineChapter 5:
Biophysical Properties of Wild-Type Superoxide Dismutase
Enzymatic Activity
Evidence Concerning Biological Function
Role of Mutant Human CuZn Superoxide Dismutase in Amyotrophic Lateral Sclerosis
DNA Damage Mediated by Metal Ions with Special Reference to Copper and Iron / Jose-Luis SagripantiChapter 6:
Binding of Metal Ions to DNA
DNA Lesions
Biological Implications of Metal-DNA Damage
Conclusion
Radical Migration Through the DNA Helix: Chemistry at a Distance / Shana O. Kelley ; Jacqueline K. BartonChapter 7:
Charge Transport in DNA: Chemical and Biological History
DNA as a Bridge for Long-Range Charge Transport
DNA as a Reactant in Long-Range Charge Transfer Reactions
Involvement of Metal Ions in Lipid Peroxidation: Biological Implications / Odile Sergent ; Isabelle Morel ; Josiane CillardChapter 8:
Outline of the Mechanism of Lipid Peroxidation
Involvement of Metal Ions in Various Stages of the Lipid Peroxidation Process
Biological Examinations of the Effect of Metal Ions on Lipid Peroxidation
Considerations on Tissue Damage
Formation of Methemoglobin and Free Radicals in Erythrocytes / Hans Nohl ; Klaus StolzeChapter 9:
ESR Detection of Free Radical Intermediates
Chemiluminescence Detection of the Ferryl Hemoglobin Protein Radical
Spin Labeling of the Erythrocyte Membrane
Iron Liberation
Reactions Involving Thiol Groups (R-SH)
Electrophoresis of Membranes with SDS-PAGE
Role of Free Radicals and Metal Ions in the Pathogenesis of Alzheimer's Disease / Craig S. Atwood ; Xudong Huang ; Robert D. Moir ; Rudolph E. Tanzi ; Ashley I. BushChapter 10:
Normal Cerebral Transition Metal Ion Homeostasis and Oxidative Metabolism
Altered Cerebral Metal Ion and Oxidative Metabolism in Alzheimer's Disease
Cerebral Amyloid Deposition in Neurological Diseases and Aging
Neurochemical Factors that Precipitate Alzheimer A[beta] Protein
Sources of Neuronal Free Radicals
Neurochemical Environments Leading to Amyloid Deposition and Neuronal Death in Alzheimer's Disease
Metal Binding and Radical Generation of Proteins in Human Neurological Diseases and Aging / Gerd Multhaup ; Colin L. MastersChapter 11:
Introduction: Transition Metal Ions in Biological Systems
Free Radicals and Human Diseases
Superoxide Dismutase in Familial Amyotrophic Lateral Sclerosis: A Gain of Function
Radical Generation of Amyloid Precursor Protein in Alzheimer's Disease
Involvement of Oxygen Radicals in A[beta] Amyloid Formation
Oxidative Stress and Antioxidants
Thiyl Radicals in Biochemically Important Thiols in the Presence of Metal Ions / Hans-Jurgen Hartmann ; Christian Sievers ; Ulrich WeserChapter 12:
Thiyl Radicals
Thiyl Radicals in the Presence of Iron, Cobalt, Nickel, Manganese, Chromium, and Vanadium
Copper(I)-Stabilized Thiyl Radicals
Improved Stabilization of Copper(I)-Thiyl Radicals Embedded in Inorganic and Biological Matrices
Methylmercury-Induced Generation of Free Radicals: Biological Implications / Theodore A. SarafianChapter 13:
Introduction: The Toxicity and Pathology of Mercury
Mercury Chemistry
Mercurial-Induced Oxidative Stress in Biological Systems
Protective Mechanisms Against Mercury Toxicity
Biological Implications
Role of Free Radicals in Metal-Induced Carcinogenesis / Joseph R. LandolphChapter 14:
The Role of Free Radicals in Chromium Carcinogenesis
The Role of Free Radicals in Nickel Carcinogenesis
The Possible Role of Free Radicals in Arsenic Carcinogenesis
Beryllium Pulmonary Fibrosis and Carcinogenesis: Is There a Role for Free Radicals?
Iron and Free Radicals: Is There a Role in Carcinogenesis or Tumor Promotion?
Copper and Free Radicals: Is There a Role in Carcinogenesis?
pH-Dependent Organocobalt Sources for Active Radical Species: a New Type of Anticancer Agents / Mark E. Vol'pin ; Ilia Ya. Levitin ; Sergei P. OsinskyChapter 15:
Introduction: Prerequisites for the Search for Potential Anticancer Drugs Among Organocobalt Complexes
Alkylcobalt(III) Chelates with Tridentate Schiff Bases
Biomedical Examinations
Conclusion and Outlook
Detection of Chromatin-Associated Hydroxyl Radicals Generated by DNA-Bound Metal Compounds and Antitumor Antibiotics / G. Mike MakrigiorgosChapter 16:
Chromatin-Associated Hydroxyl Radicals
Detection of Chromatin-Associated Hydroxyl Radicals
Methods for Attaching SECCA to In Vitro Chromatin Models
Metal Compounds and Antitumor Antibiotics that Generate Chromatin-Associated HO
Nitric Oxide (No): Formation and Biological Roles in Mammalian Systems / Jon M. Fukuto ; David A. WinkChapter 17:
Biologically Relevant Chemistry of Nitric Oxide
Nitric Oxide Biosynthesis
Physiology and Pathophysiology of Nitric Oxide: A Chemical Perspective
Chemistry of Peroxynitrite and Its Relevance to Biological Systems / Willem H. KoppenolChapter 18:
Introduction and Brief Historical Overview
Is Peroxynitrite Formed in vivo?
Syntheses
Properties, Isomerization, and Decomposition
Reactions that Are First Order in Peroxynitrous Acid
Biomolecular Reactions
Superoxide Dismutase and Peroxynitrite
Peroxynitrite or Hydroxyl Radical?
Note Added in Proof
Novel Nitric Oxide-Liberating Heme Proteins from the Saliva of Bloodsucking Insects / F. Ann Walker ; Jose M. C. Ribeiro ; William R. MontfortChapter 19:
Strategies Used by Bloodsucking Insects to Ensure that They Obtain a Sufficient Blood Meal
Properties of Nitric Oxide
Spectroscopy of the Nitrophorins of Rhodnius prolixus in Comparison to Other Heme Proteins
Redox Chemistry of Nitric Oxide-Heme Systems and the Nitrophorins of Rhodnius prolixus
X-Ray Crystallography
Other Metal-Nitric Oxide Complexes of Importance in Inorganic Chemistry and Biochemistry
Summary
Nitrogen Monoxide-Related Disease and Nitrogen Monoxide Scavengers as Potential Drugs / Simon P. FrickerChapter 20:
Nitric Oxide and Disease
Therapeutic Strategies
Organic Molecules as Nitric Oxide Scavengers
Inorganic Molecules as Scavengers
Ruthenium Complexes
Therapeutics of Nitric Oxide Modulation / Ho-Leung Fung ; Brian P. Booth ; Mohammad Tabrizi-FardChapter 21:
Diversity of Molecular Forms of Nitric Oxide
Interactions Between Nitric Oxide and Calcitonin-Gene Related Peptide (CGRP)
Therapeutics of Nitric Oxide Enhancement
Therapeutics of Nitric Oxide Inhibition
Subject Index
Preface to the Series
Preface to Volume 36
Contributors
5.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, 1998  xlii, 775 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 35
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Biological cycling of iron in the sea
microbial iron transport - iron acquisition by pathogenic microorganisms
bacterial iron transport - mechanisms, genetics and regulation
molecular biology of iron transport in fungi
soil microorganisms and iron uptake by higher plants
iron transport in gaminaceous plants
the coordination chemistry of siderophores - thermodynamics and kinetics of iron chelation and release
biomimetic siderophores - from structural probes to diagnostic tools
Biological cycling of iron in the sea
microbial iron transport - iron acquisition by pathogenic microorganisms
bacterial iron transport - mechanisms, genetics and regulation
6.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c1997  xlii, 604 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 34
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Analytical methods for the determination of mercury (II) and methylmercury compounds - the problem of specification
mercury in lakes and rivers
biogeochemical cycling of mercury in the marine environment
catchments as a source of mercury/methylmercury in boreal surface waters
gold rushes and mercury pollution
accumulation of mercury in soil and effects on the soil biota
biogeochemistry of mercury in the air-soil-plant system
microbial transformation of mercury species and their
Analytical methods for the determination of mercury (II) and methylmercury compounds - the problem of specification
mercury in lakes and rivers
biogeochemical cycling of mercury in the marine environment
7.

図書

図書
edited by Helmut Sigel and Astrid Sigel
出版情報: New York : Marcel Dekker, c1995  xxxix, 779 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 31
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Inorganic considerations on the function of vanadium in biological systems
solution properties of vanadium(III) with regard to biological systems
the vanadyl ion - molecular structure of co-ordinating ligands by electron paramagnetic resonance and electron nuclear resonance-spectroscopy
vanadyl(IV) complexes of nucleotides
interactions of vanadates(V) with biogenic ligands
use of vanadate-induced photocleavage for detecting phosphate-binding sites in proteins
vanadium-protein by
Inorganic considerations on the function of vanadium in biological systems
solution properties of vanadium(III) with regard to biological systems
the vanadyl ion - molecular structure of co-ordinating ligands by electron paramagnetic resonance and electron nuclear resonance-spectroscopy
8.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c1996  xxxix, 814 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 32
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Phosphate-metal ion interactions of nucleotides and polynucleotides
sugar-metal ion interactions
dichotomy of metal ion binding to N1 and N7 of purines
general conclusions from sold state studies of nucleotide-metal ion complexes
solution studies of nucleotide-metal ion complexes - isomeric equilibria
stacking interactions involving nucleotides and metal ion complexes
the effect of metal ions on hydrolytic reactions of nucleotides and their phosphoesters
metal complexes of from
Phosphate-metal ion interactions of nucleotides and polynucleotides
sugar-metal ion interactions
dichotomy of metal ion binding to N1 and N7 of purines
9.

図書

図書
edited by Astrid Sigel and Helmut Sigel
出版情報: New York : Marcel Dekker, c1996  xli, 678 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 33
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Molecular modelling of transition metal adducts with nucleic acids and their constituents
zinc complexes as targeting agents for nucleic acids
metallocene interactions with DNA and DNA processing enzymes
evidences for a catalytic activity of the DNA double helix in the reactions between DNA, platinum (II) and intercalators
trans-diammineplatinum (II) - what makes it different from CIS-DDP?
coordination chemistry of a neglected relative of cisplatin and its interaction with nucleic
Molecular modelling of transition metal adducts with nucleic acids and their constituents
zinc complexes as targeting agents for nucleic acids
metallocene interactions with DNA and DNA processing enzymes
10.

図書

図書
edited by Helmut Sigel with the assistance of Astrid Sigel
出版情報: New York : M. Dekker, c1984  xxiii, 532 p. ; 24 cm
シリーズ名: Metal ions in biological systems / edited by Helmut Sigel ; v. 17
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