Preface |
Organization and Features of The Cell |
Acknowledgments |
Reviewers |
Supplements to Accompany The Cell |
Introduction / Part I: |
An Overview of Cells and Cell Research / 1: |
The Origin and Evolution of Cells |
Cells as Experimental Models |
Tools of Cell Biology |
The Chemistry of Cells / 2: |
The Molecular Composition of Cells |
The Central Role of Enzymes as Biological Catalysts |
Metabolic Energy |
The Biosynthesis of Cell Constituents |
Cell Membranes |
Fundamentals of Molecular Biology / 3: |
Heredity, Genes, and DNA |
Expression of Genetic Information |
Recombinant DNA |
Detection of Nucleic Acids and Proteins |
Gene Function in Eukaryotes |
The Flow of Genetic Information / Part II: |
The Organization of Cellular Genomes / 4: |
The Complexity of Eukaryotic Genomes |
Chromosomes and Chromatin |
The Sequences of Complete Genomes |
The Human Genome |
Replication, Maintenance, and Rearrangements of Genomic DNA / 5: |
DNA Replication |
DNA Repair |
Recombination Between Homologous DNA Sequences |
DNA Rearrangements |
RNA Synthesis and Processing / 6: |
Transcription in Prokaryotes |
Eukaryotic RNA Polymerases and General Transcription Factors |
Regulation of Transcription in Eukaryotes |
RNA Processing and Turnover |
Protein Synthesis, Processing, and Regulation / 7: |
Translation of mRNA |
Protein Folding and Processing |
Regulation of Protein Function |
Protein Degradation |
Cell Structure and Function / Part III: |
The Nucleus / 8: |
The Nuclear Envelope and Traffic Between the Nucleus and Cytoplasm |
Internal Organization of the Nucleus |
The Nucleolus |
The Nucleus During Mitosis |
Protein Sorting and Transport: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes / 9: |
The Endoplasmic Reticulum |
The Golgi Apparatus |
The Mechanism of Vesicular Transport |
Lysosomes |
Bioenergetics and Metabolism: Mitochondria, Chloroplasts, and Peroxisomes / 10: |
Mitochondria |
The Mechanism of Oxidative Phosphorylation |
Chloroplasts and other Plastids |
Photosynthesis |
Peroxisomes |
The Cytoskeleton and Cell Movement / 11: |
Structure and Organization of Actin Filaments |
Actin, Myosin, and Cell Movement |
Intermediate Filaments |
Microtubules |
Microtubule Motors and Movements |
The Cell Surface / 12: |
Structure of the Plasma Membrane |
Transport of Small Molecules |
Endocytosis |
Cell Walls and the Extracellular Matrix |
Cell-Cell Interactions |
Cell Regulation / Part IV: |
Cell Signaling / 13: |
Signaling Molecules and Their Receptors |
Functions of Cell Surface Receptors |
Pathways of Intracellular Signal Transduction |
Signal Transduction and the Cytoskeleton |
Signaling in Development and Differentiation |
Regulation of Programmed Cell Death |
The Cell Cycle / 14: |
The Eukaryotic Cell Cycle |
Regulators of Cell Cycle Progression |
The Events of M Phase |
Meiosis and Fertilization |
Cell Proliferation in Development and Differentiation |
Cancer / 15: |
The Development and Causes of Cancer |
Tumor Viruses |
Oncogenes |
Tumor Suppressor Genes |
Applications of Molecular Biology to Cancer Prevention and Treatment |
Answers to Questions |
Glossary |
Index |
Preface |
Organization and Features of The Cell |
Acknowledgments |